TW201121966A - Fused heterocyclic compounds as orexin receptor modulators - Google Patents
Fused heterocyclic compounds as orexin receptor modulators Download PDFInfo
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- TW201121966A TW201121966A TW099136020A TW99136020A TW201121966A TW 201121966 A TW201121966 A TW 201121966A TW 099136020 A TW099136020 A TW 099136020A TW 99136020 A TW99136020 A TW 99136020A TW 201121966 A TW201121966 A TW 201121966A
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- diazabicyclo
- phenyl
- octane
- fluoro
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- 108050000742 Orexin Receptor Proteins 0.000 title abstract 2
- 102000008834 Orexin receptor Human genes 0.000 title abstract 2
- 150000002391 heterocyclic compounds Chemical class 0.000 title 1
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Landscapes
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| EA024106B1 (ru) | 2011-11-08 | 2016-08-31 | Актелион Фармасьютиклз Лтд. | Производные 2-(1,2,3-триазол-2-ил)бензамида и 3-(1,2,3-триазол-2-ил)пиколинамида |
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| RU2014136339A (ru) | 2012-02-07 | 2016-03-27 | Иолас Терапьютикс, Инк. | Замещенные пролины/пиперидины как антагонисты орексиновых рецепторов |
| PT2855453T (pt) | 2012-06-04 | 2017-03-09 | Actelion Pharmaceuticals Ltd | Derivados de benzimidazol-prolina |
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| CN103012293A (zh) * | 2012-12-13 | 2013-04-03 | 同济大学 | 一种抗失眠药物mk-4305中间体的合成方法 |
| WO2014113303A1 (en) * | 2013-01-16 | 2014-07-24 | Merck Sharp & Dohme Corp. | 4-fluoropiperidine orexin receptor antagonists |
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2010
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| EP2491034B1 (en) | 2013-12-18 |
| US8680275B2 (en) | 2014-03-25 |
| PE20110296A1 (es) | 2011-05-21 |
| EP2491034A1 (en) | 2012-08-29 |
| AR078733A1 (es) | 2011-11-30 |
| UY32968A (es) | 2011-04-29 |
| JP2013508404A (ja) | 2013-03-07 |
| WO2011050200A1 (en) | 2011-04-28 |
| CL2010001159A1 (es) | 2011-05-06 |
| HK1175461A1 (en) | 2013-07-05 |
| JP5847087B2 (ja) | 2016-01-20 |
| US20120202783A1 (en) | 2012-08-09 |
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