TW200838551A - Methods for treating hypercholesterolemia - Google Patents
Methods for treating hypercholesterolemia Download PDFInfo
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- TW200838551A TW200838551A TW096145015A TW96145015A TW200838551A TW 200838551 A TW200838551 A TW 200838551A TW 096145015 A TW096145015 A TW 096145015A TW 96145015 A TW96145015 A TW 96145015A TW 200838551 A TW200838551 A TW 200838551A
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- C12N2310/30—Chemical structure
- C12N2310/34—Spatial arrangement of the modifications
- C12N2310/346—Spatial arrangement of the modifications having a combination of backbone and sugar modifications
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| US86739506P | 2006-11-27 | 2006-11-27 | |
| US91289207P | 2007-04-19 | 2007-04-19 | |
| US98628607P | 2007-11-07 | 2007-11-07 | |
| US98807407P | 2007-11-14 | 2007-11-14 |
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| TW096145015A TW200838551A (en) | 2006-11-27 | 2007-11-27 | Methods for treating hypercholesterolemia |
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| JP2009536222A (ja) | 2006-05-05 | 2009-10-08 | アイシス ファーマシューティカルズ， インコーポレーテッド | Ｐｃｓｋ９の発現を調節するための化合物および方法 |
| CN101484588B (zh) * | 2006-05-11 | 2013-11-06 | 阿尔尼拉姆医药品有限公司 | 抑制pcsk9基因表达的组合物和方法 |
| US7572618B2 (en) | 2006-06-30 | 2009-08-11 | Bristol-Myers Squibb Company | Polynucleotides encoding novel PCSK9 variants |
| CA2658183A1 (en) | 2006-07-17 | 2008-01-24 | Sirna Therapeutics Inc. | Rna interference mediated inhibition of proprotein convertase subtilisin kexin 9 (pcsk9) gene expression using short interfering nucleic acid (sina) |
| CA2666191C (en) | 2006-10-09 | 2017-07-11 | Santaris Pharma A/S | Rna antagonist compounds for the modulation of pcsk9 |
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| US8093222B2 (en) * | 2006-11-27 | 2012-01-10 | Isis Pharmaceuticals, Inc. | Methods for treating hypercholesterolemia |
| CA2670563A1 (en) | 2006-11-27 | 2008-06-05 | Isis Pharmaceuticals, Inc. | Methods for treating hypercholesterolemia |
| WO2008109369A2 (en) | 2007-03-02 | 2008-09-12 | Mdrna, Inc. | Nucleic acid compounds for inhibiting tnf gene expression and uses thereof |
| US20100105134A1 (en) | 2007-03-02 | 2010-04-29 | Mdrna, Inc. | Nucleic acid compounds for inhibiting gene expression and uses thereof |
| WO2009148605A2 (en) | 2008-06-04 | 2009-12-10 | Isis Pharmaceuticals, Inc. | Methods for treating hypercholesterolemia |
-
2007
- 2007-11-27 CA CA002670563A patent/CA2670563A1/en not_active Abandoned
- 2007-11-27 TW TW096145015A patent/TW200838551A/zh unknown
- 2007-11-27 JP JP2009539274A patent/JP2010510807A/ja active Pending
- 2007-11-27 EP EP11192464A patent/EP2453016A1/en not_active Withdrawn
- 2007-11-27 EP EP11192458A patent/EP2455471A3/en not_active Withdrawn
- 2007-11-27 AU AU2007325767A patent/AU2007325767A1/en not_active Abandoned
- 2007-11-27 US US12/516,457 patent/US8084437B2/en active Active
- 2007-11-27 MX MX2009005527A patent/MX2009005527A/es not_active Application Discontinuation
- 2007-11-27 WO PCT/US2007/024369 patent/WO2008066776A2/en not_active Ceased
- 2007-11-27 EA EA200900741A patent/EA200900741A1/ru unknown
- 2007-11-27 EP EP07862213A patent/EP2102340A2/en not_active Withdrawn
- 2007-11-27 KR KR1020097013295A patent/KR20090103894A/ko not_active Withdrawn
-
2009
- 2009-05-20 IL IL198851A patent/IL198851A0/en unknown
- 2009-06-03 NO NO20092150A patent/NO20092150L/no not_active Application Discontinuation
- 2009-06-26 CO CO09066682A patent/CO6241169A2/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| US8084437B2 (en) | 2011-12-27 |
| EP2455471A3 (en) | 2012-09-12 |
| AU2007325767A2 (en) | 2009-07-09 |
| IL198851A0 (en) | 2011-08-01 |
| WO2008066776A3 (en) | 2008-09-25 |
| WO2008066776A2 (en) | 2008-06-05 |
| JP2010510807A (ja) | 2010-04-08 |
| AU2007325767A1 (en) | 2008-06-05 |
| EP2102340A2 (en) | 2009-09-23 |
| NO20092150L (no) | 2009-07-31 |
| MX2009005527A (es) | 2009-06-08 |
| CA2670563A1 (en) | 2008-06-05 |
| EP2453016A1 (en) | 2012-05-16 |
| US20100144834A1 (en) | 2010-06-10 |
| EP2455471A2 (en) | 2012-05-23 |
| EA200900741A1 (ru) | 2010-04-30 |
| KR20090103894A (ko) | 2009-10-01 |
| CO6241169A2 (es) | 2011-01-20 |
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