TR201901862T4 - Antibiyotiğe karşı dirençli bakterilerin saptanmasına yönelik bir yöntem ve kit. - Google Patents
Antibiyotiğe karşı dirençli bakterilerin saptanmasına yönelik bir yöntem ve kit. Download PDFInfo
- Publication number
- TR201901862T4 TR201901862T4 TR2019/01862T TR201901862T TR201901862T4 TR 201901862 T4 TR201901862 T4 TR 201901862T4 TR 2019/01862 T TR2019/01862 T TR 2019/01862T TR 201901862 T TR201901862 T TR 201901862T TR 201901862 T4 TR201901862 T4 TR 201901862T4
- Authority
- TR
- Turkey
- Prior art keywords
- oxa
- kit
- group
- resistant bacteria
- detecting antibiotic
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 241000894006 Bacteria Species 0.000 title abstract 2
- 230000003115 biocidal effect Effects 0.000 title 1
- 239000003155 DNA primer Substances 0.000 abstract 1
- 101000740458 Enterobacter cloacae Imipenem-hydrolyzing beta-lactamase Proteins 0.000 abstract 1
- 101000740455 Klebsiella pneumoniae Metallo-beta-lactamase type 2 Proteins 0.000 abstract 1
- 101100337539 Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) gim-1 gene Proteins 0.000 abstract 1
- YZBQHRLRFGPBSL-RXMQYKEDSA-N carbapenem Chemical compound C1C=CN2C(=O)C[C@H]21 YZBQHRLRFGPBSL-RXMQYKEDSA-N 0.000 abstract 1
- 108010068385 carbapenemase Proteins 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/16—Primer sets for multiplex assays
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
Mevcut buluş, bakterilerde karbapenem direncine yol açan karbapenemaz dirençli genleri saptamaya yönelik bir yöntem ve kit ile ilgilidir. Buluş aynı zamanda, saptamada kullanılabilen, oligonükleotit primerleri sağlamaktadır. Yöntem, tek bir tepkimenin içinde OXA-48, SME, GIM-1, VIM 1-22, SPM, GES 1-10, KPC 1-7, IMI 5 1-3/NMC-A, IMP 1-24'ü ve başka bir tek bir tepkimenin içinde OXA-23 grubu, -OXA-24 grubu, ISabal promotöre sahip OXA-51 grubu, OXA-55, OXA-58, OXA-60, OXA-62, CMY 1,-10,-11 SFC-1, NDM-1, ve SIM-1'i saptamak için kullanılabilmektedir.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FI20095544A FI20095544A0 (fi) | 2009-05-15 | 2009-05-15 | Menetelmä ja kitti antibioottiresistenttien bakteerien tunnistusta varten |
Publications (1)
Publication Number | Publication Date |
---|---|
TR201901862T4 true TR201901862T4 (tr) | 2019-03-21 |
Family
ID=40680725
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2019/01862T TR201901862T4 (tr) | 2009-05-15 | 2010-05-17 | Antibiyotiğe karşı dirençli bakterilerin saptanmasına yönelik bir yöntem ve kit. |
Country Status (13)
Country | Link |
---|---|
US (1) | US9593381B2 (tr) |
EP (1) | EP2430188B1 (tr) |
JP (2) | JP6054178B2 (tr) |
CN (1) | CN102482712B (tr) |
AU (1) | AU2010247321B2 (tr) |
CA (1) | CA2761915C (tr) |
DK (1) | DK2430188T5 (tr) |
ES (1) | ES2711534T3 (tr) |
FI (1) | FI20095544A0 (tr) |
PL (1) | PL2430188T3 (tr) |
PT (1) | PT2430188T (tr) |
TR (1) | TR201901862T4 (tr) |
WO (1) | WO2010130882A1 (tr) |
Families Citing this family (33)
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US20130273535A1 (en) * | 2010-08-17 | 2013-10-17 | Smiths Detection-Watford Ltd. | Ndm-1 polymerase chain reaction (pcr) assay |
CN102002528B (zh) * | 2010-11-22 | 2012-09-26 | 浙江省疾病预防控制中心 | 一种抗生素耐药ndm-1基因的荧光检测试剂盒及检测方法 |
CN102533961B (zh) * | 2010-12-30 | 2016-03-02 | 上海星耀医学科技发展有限公司 | 用于检测新德里金属β内酰胺酶-1基因的靶序列与试剂盒 |
CN102719519B (zh) * | 2011-03-30 | 2014-07-02 | 北京鑫诺美迪基因检测技术有限公司 | 用于检测Ⅰ型新德里金属β-内酰胺酶基因的组合物和试剂盒 |
CN102181543B (zh) * | 2011-04-08 | 2013-06-05 | 北京爱普益生物科技有限公司 | 用于检测blaNDM-1基因的引物、探针、试剂盒及其检测方法 |
CN102242197B (zh) * | 2011-05-19 | 2013-05-22 | 中国人民解放军疾病预防控制所 | 用于检测ndm-1基因的lamp试剂盒及其专用引物 |
WO2013011072A1 (en) * | 2011-07-20 | 2013-01-24 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Carbapenemase and antibacterial treatment |
KR101323575B1 (ko) | 2011-08-12 | 2013-10-30 | 연세대학교 산학협력단 | Ndm-1 유전자 및 x 유전자를 이용하여 항균 감수성 증강제를 스크리닝하는 방법 |
KR101323580B1 (ko) * | 2011-08-16 | 2013-10-30 | 연세대학교 산학협력단 | phnF 단백질 등을 이용하여 항균 감수성 증강제를 스크리닝하는 방법 |
CN102952875B (zh) * | 2011-08-31 | 2014-08-27 | 宁波市第二医院 | 细菌耐药基因检测方法、基因芯片和试剂盒 |
RU2012124221A (ru) * | 2012-06-13 | 2013-12-20 | Валерий Денисович Белокрылов | Способ и автоматизированное устройство для диагностики заболеваний пищевода, желудка и двенадцатиперстной кишки, инфицированных генами бактерий ndm-1 и их мутациями |
FR2993900B1 (fr) * | 2012-07-27 | 2016-03-25 | Biomerieux Sa | Procede de detection de bacteries productrices de carbapenemases de type oxa-48 |
CN102965377B (zh) * | 2012-08-30 | 2014-04-16 | 广东医学院 | 一种新德里金属β内酰胺酶1核酸适体及其筛选方法和应用 |
CN102899414A (zh) * | 2012-10-10 | 2013-01-30 | 南方医科大学 | 超级细菌ndm和kpc基因双重荧光定量pcr检测方法及其试剂盒 |
WO2014102761A2 (es) * | 2012-12-31 | 2014-07-03 | Conselleria De Sanitat | Cebadores para detección y tipificación de cepas bacterianas productoras de carbapenemasas, kit y método de detección |
CN103088144A (zh) * | 2013-01-30 | 2013-05-08 | 中国人民解放军军事医学科学院放射与辐射医学研究所 | 一种肺炎克雷伯菌kpc型碳青霉烯酶基因核酸检测试剂盒 |
CN103088146B (zh) * | 2013-02-06 | 2014-07-16 | 台州市立医院 | 一种检测含有kpc-15基因肺炎克雷伯菌的pcr试剂盒 |
KR20170026322A (ko) * | 2014-03-13 | 2017-03-08 | 옵젠, 인크. | 다제 내성균의 검출 방법 |
GB201419330D0 (en) * | 2014-10-30 | 2014-12-17 | Sec Dep For Health The | Detection method |
GB201503387D0 (en) * | 2015-02-27 | 2015-04-15 | ALERE TECHNOLOGIES GmbH | Anti-carbapenem antibodies and uses thereof |
WO2016094162A1 (en) | 2014-12-12 | 2016-06-16 | Elitechgroup B.V. | Methods and compositions for detecting antibiotic resistant bacteria |
WO2016094607A2 (en) * | 2014-12-12 | 2016-06-16 | Elitechgroup B.V. | Methods and compositions for detecting antibiotic resistant bacteria |
CN104774941A (zh) * | 2015-04-08 | 2015-07-15 | 中国人民解放军军事医学科学院放射与辐射医学研究所 | 碳青霉烯类抗生素耐药基因检测dna芯片的制备和用途 |
CN104774949B (zh) * | 2015-04-20 | 2017-08-11 | 海宁市疾病预防控制中心 | 一种肺炎克雷伯菌碳青霉烯酶基因型检测方法 |
CN104975087B (zh) * | 2015-06-23 | 2019-02-01 | 中山大学 | 一种快速检测细菌超广谱β-内酰胺酶耐药基因SME的诊断方法 |
DE202015103615U1 (de) | 2015-07-09 | 2015-10-20 | Valeriy D. Belokrylov | Automatisiertes Gerät für eine Diagnose und die primäre Therapie in Echtzeit der Erkrankungen des Mastdarms infiziert Bakterien, die das GEN NDM-1 umfassen |
CA3027953A1 (en) | 2016-06-15 | 2017-12-21 | Streck, Inc. | Assays and methods for determining microbial resistance |
JP6298112B2 (ja) * | 2016-07-26 | 2018-03-20 | サミー株式会社 | 遊技機 |
WO2018232028A1 (en) * | 2017-06-14 | 2018-12-20 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Detection of blaimp antibacterial resistance genes |
CN109628620B (zh) * | 2019-01-22 | 2023-05-05 | 南方医科大学南方医院 | 全序列荧光pcr检测oxa-23家族和oxa-51家族基因型的引物、方法及试剂盒 |
WO2020243644A1 (en) * | 2019-05-31 | 2020-12-03 | Streck, Inc. | Detection of antibiotic resistance genes |
CN111996271A (zh) * | 2020-09-18 | 2020-11-27 | 山东省兽药质量检验所(山东省畜产品质量检测中心) | 超级细菌耐药基因ndm-1的rpa检测引物组、试剂盒和方法 |
CN114755420B (zh) * | 2022-05-30 | 2023-02-03 | 广东聚诚生物技术有限公司 | 碳青霉烯酶联合检测试剂盒 |
Family Cites Families (11)
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AU2002312764A1 (en) * | 2001-03-15 | 2002-10-21 | Schrenzel, Jacques | Detection of methicillin-resistant staphylococcus aureus (mrsa) |
WO2003048377A2 (en) | 2001-11-30 | 2003-06-12 | University Of Rochester | Multiplex real-time quantitative pcr |
US7045291B2 (en) * | 2002-05-17 | 2006-05-16 | Creighton University | Multiplex PCR for the detection of AmpC beta-lactamase genes |
US7449293B2 (en) * | 2003-09-26 | 2008-11-11 | Children's Hospital & Research Center At Oakland | Methods and compositions for detecting Bacillus species |
JP4859088B2 (ja) * | 2004-10-25 | 2012-01-18 | 独立行政法人理化学研究所 | 2型糖尿病に関連するヒトwnt5b遺伝子多型の検出方法及びキット |
WO2007023461A2 (en) * | 2005-08-26 | 2007-03-01 | Philips Intellectual Property & Standards Gmbh | Method for detection of micro-organisms and antibiotic resistance markers and nucleic acid oligonucleotides therefor |
JP2007195421A (ja) | 2006-01-24 | 2007-08-09 | Eiken Chem Co Ltd | メタロ−β−ラクタマーゼ遺伝子検出用のプライマー、メタロ−β−ラクタマーゼ遺伝子の検出方法及びβ−ラクタム薬耐性菌の検出方法 |
CA2649456A1 (en) * | 2006-05-25 | 2007-12-06 | Creighton University | Primers for use in detecting metallo-beta-lactamases |
JP5184359B2 (ja) * | 2006-08-21 | 2013-04-17 | 満男 海老澤 | 半田鏝、それを用いて電子機器を製造する方法、及び製造装置 |
KR100868765B1 (ko) | 2006-09-29 | 2008-11-17 | 삼성전자주식회사 | 항생제 내성 박테리아의 표적 서열을 증폭시킬 수 있는프라이머 세트, 박테리아의 표적 서열에 특이적으로혼성화하는 프로브 세트, 상기 프로브 세트가 고정화되어있는 마이크로어레이 및 상기 프로브 세트를 이용하여박테리아의 존재를 검출하는 방법 |
ATE534753T1 (de) * | 2007-04-06 | 2011-12-15 | Becton Dickinson Co | Zusammensetzungen und verfahren zur identifikation eines carbapenemase-gens |
-
2009
- 2009-05-15 FI FI20095544A patent/FI20095544A0/fi not_active Application Discontinuation
-
2010
- 2010-05-17 PL PL10723161T patent/PL2430188T3/pl unknown
- 2010-05-17 AU AU2010247321A patent/AU2010247321B2/en active Active
- 2010-05-17 WO PCT/FI2010/050395 patent/WO2010130882A1/en active Application Filing
- 2010-05-17 TR TR2019/01862T patent/TR201901862T4/tr unknown
- 2010-05-17 CA CA2761915A patent/CA2761915C/en active Active
- 2010-05-17 DK DK10723161.5T patent/DK2430188T5/en active
- 2010-05-17 EP EP10723161.5A patent/EP2430188B1/en active Active
- 2010-05-17 CN CN201080021305.0A patent/CN102482712B/zh active Active
- 2010-05-17 PT PT10723161T patent/PT2430188T/pt unknown
- 2010-05-17 JP JP2012510325A patent/JP6054178B2/ja active Active
- 2010-05-17 ES ES10723161T patent/ES2711534T3/es active Active
-
2011
- 2011-11-15 US US13/297,020 patent/US9593381B2/en active Active
-
2016
- 2016-01-04 JP JP2016000276A patent/JP6258360B2/ja active Active
Also Published As
Publication number | Publication date |
---|---|
PL2430188T3 (pl) | 2019-07-31 |
CN102482712A (zh) | 2012-05-30 |
WO2010130882A1 (en) | 2010-11-18 |
PT2430188T (pt) | 2019-02-19 |
DK2430188T3 (en) | 2019-03-11 |
EP2430188A1 (en) | 2012-03-21 |
DK2430188T5 (en) | 2019-03-18 |
EP2430188B1 (en) | 2018-11-14 |
JP2012526540A (ja) | 2012-11-01 |
ES2711534T3 (es) | 2019-05-06 |
FI20095544A0 (fi) | 2009-05-15 |
JP2016146818A (ja) | 2016-08-18 |
US20120129180A1 (en) | 2012-05-24 |
JP6054178B2 (ja) | 2016-12-27 |
AU2010247321B2 (en) | 2016-05-19 |
CN102482712B (zh) | 2020-09-15 |
JP6258360B2 (ja) | 2018-01-10 |
CA2761915C (en) | 2019-01-08 |
AU2010247321A1 (en) | 2012-01-19 |
CA2761915A1 (en) | 2010-11-18 |
US9593381B2 (en) | 2017-03-14 |
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