TR200102386T2 - Yüksek tansiyon tedavisi için ilaç. - Google Patents

Yüksek tansiyon tedavisi için ilaç.

Info

Publication number
TR200102386T2
TR200102386T2 TR2001/02386T TR200102386T TR200102386T2 TR 200102386 T2 TR200102386 T2 TR 200102386T2 TR 2001/02386 T TR2001/02386 T TR 2001/02386T TR 200102386 T TR200102386 T TR 200102386T TR 200102386 T2 TR200102386 T2 TR 200102386T2
Authority
TR
Turkey
Prior art keywords
blood pressure
treatment
high blood
medication
relates
Prior art date
Application number
TR2001/02386T
Other languages
English (en)
Inventor
R. Wilkins Martin
Thorm�Hlen Dirk
Waldeck Harald
Original Assignee
Solvay Pharmaceuticals Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Solvay Pharmaceuticals Gmbh filed Critical Solvay Pharmaceuticals Gmbh
Publication of TR200102386T2 publication Critical patent/TR200102386T2/tr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Abstract

Eldeki bulus azot atomuna alfa pozisyonunda bir okso grubu içeren ve 3 pozisyonunda 1-(karboksi alkil)-siklo pentil-karbonil-amino artigi ile ikame edilen benzazepin-N-asetik asit türevlerinin ve tuzlarinin ve biyolabil esterlerinin yüksek tansiyon tedavisinde, özellikle sekonder yüksek tansiyonun belirli türlerinin tedavisinde büyük memeli hayvanlarda ve özellikle insanlarda ve bu tedavi için uygun ilaçlarin imalatinda kullanilmasi ile ilgilidir. Tedavi edilmesi gereken yüksek tansiyonun nedeni burada farkli olusumlara dayanir. Bulus özellikle sekonder yüksek tansiyonun kardiyal olmayan degisik hastaliklardan dolayi olusan türleriyle ilgilidir.
TR2001/02386T 1999-02-16 2000-02-10 Yüksek tansiyon tedavisi için ilaç. TR200102386T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19906310A DE19906310A1 (de) 1999-02-16 1999-02-16 Arzneimittel zur Behandlung von Bluthochdruck

Publications (1)

Publication Number Publication Date
TR200102386T2 true TR200102386T2 (tr) 2002-01-21

Family

ID=7897580

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2001/02386T TR200102386T2 (tr) 1999-02-16 2000-02-10 Yüksek tansiyon tedavisi için ilaç.

Country Status (28)

Country Link
US (1) US6482820B2 (tr)
EP (1) EP1154777B1 (tr)
JP (1) JP2002537258A (tr)
KR (2) KR100797665B1 (tr)
CN (1) CN1198619C (tr)
AR (1) AR036864A1 (tr)
AT (1) ATE295174T1 (tr)
AU (1) AU773240C (tr)
BR (1) BR0008260A (tr)
CA (1) CA2362273C (tr)
CZ (1) CZ301499B6 (tr)
DE (2) DE19906310A1 (tr)
DZ (1) DZ3014A1 (tr)
ES (1) ES2238268T3 (tr)
HK (1) HK1042247B (tr)
HU (1) HUP0105491A3 (tr)
IL (1) IL144622A (tr)
NO (1) NO329588B1 (tr)
NZ (1) NZ514058A (tr)
PL (1) PL195283B1 (tr)
PT (1) PT1154777E (tr)
RU (1) RU2270679C2 (tr)
SK (1) SK287254B6 (tr)
TR (1) TR200102386T2 (tr)
TW (1) TWI221770B (tr)
UA (1) UA63032C2 (tr)
WO (1) WO2000048601A1 (tr)
ZA (1) ZA200105828B (tr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19932555A1 (de) * 1999-07-13 2001-01-18 Solvay Pharm Gmbh Arzneimittel mit protektiver Wirkung gegen oxidativ-toxische und insbesondere gegen kardiotoxische Substanzen
DE60040089D1 (de) * 1999-11-19 2008-10-09 Solvay Pharm Bv Menschliches homolog aus der familie der metalloproteasen
ES2288899T3 (es) * 2000-10-04 2008-02-01 Astellas Pharma Inc. Uso de un antagonista de vasopresina tal como conivaptan en la fabricacion de un medicamento para el tratamiento de la hipertension pulmonar.
CN1520299A (zh) * 2001-05-18 2004-08-11 ������ҩ�����޹�˾ 具有nep/mp-联合抑制活性的化合物在制备药物中的用途
PT1448567E (pt) * 2001-09-10 2010-03-12 Tibotec Pharm Ltd Método de preparação de hexa-hidro-furo[2,3-b]furan-3-ol
JP4384495B2 (ja) * 2002-01-16 2009-12-16 ソルベイ・フアーマシユーチカルズ・ベー・ブイ 固体のベンズアゼピン化合物の塩および医薬化合物の調製におけるそれらの使用
AR038681A1 (es) * 2002-02-14 2005-01-26 Solvay Pharm Bv Formulacion oral de solucion solida de una sustancia activa pobremente soluble en agua
WO2004062692A1 (en) * 2003-01-13 2004-07-29 Solvay Pharmaceuticals B.V. Formulation of poorly water-soluble active substances
SA04250283B1 (ar) * 2003-09-26 2008-05-26 سولفاي فارماسيتيكالز جي أم بي أتش مشتقات من amidomethy1-substituted1-(carboxyalkyl)-cyclopentylcarbonylamino-benzazepine-N-acetic acid
US7262184B2 (en) 2003-09-26 2007-08-28 Solvay Pharmaceuticals Gmbh Amidomethyl-substituted 1-(carboxyalkyl) cyclopentyl-carbonylamino-benzazepine-N-acetic acid compounds, process and intermediate products for their preparation and pharmaceutical compositions containing them
US7427611B2 (en) 2003-09-26 2008-09-23 Solvay Pharmaceuticals Gmbh Amidomethyl-substituted 1-(carboxyalkyl)-cyclopentyl-carbonylamino-benzazepine-N-acetic acid compounds, process and intermediate products for their preparation and pharmaceutical compositions containing them
US7452875B2 (en) 2003-09-26 2008-11-18 Solvay Pharmaceuticals Gmbh Amidomethyl-substituted 1-(carboxyalkyl) cyclopentyl-carbonylamino-benzazepine-N-acetic acid compounds, process and intermediate products for their preparation and pharmaceutical compositions containing them
PL1687006T3 (pl) * 2003-11-18 2008-01-31 Solvay Pharm Gmbh Kompozycje farmaceutyczne do leczenia zaburzeń czynności nerek
US20050267124A1 (en) * 2004-05-14 2005-12-01 Solvay Pharmaceuticals Gmbh Pharmaceutical compositions comprising NEP-inhibitors, inhibitors of the endogenous producing system and PDEV inhibiitors
US20050267072A1 (en) * 2004-05-14 2005-12-01 Solvay Pharmaceuticals Gmbh Pharmaceutical compositions containing dually acting inhibitors of neutral endopeptidase for the treatment of sexual dysfunction
US20050288272A1 (en) * 2004-06-23 2005-12-29 Solvay Pharmaceuticals Gmbh Pharmaceutical compositions comprising NEP-inhibitors, inhibitors of the endogenous endothelin producing system and AT1 receptor antagonists
CN101080232A (zh) 2004-12-15 2007-11-28 索尔瓦药物有限公司 包含NEP－抑制剂、内源性内皮素产生系统的抑制剂和HMG CoA还原酶抑制剂的药物组合物
US20060205625A1 (en) * 2005-02-18 2006-09-14 Solvay Pharmaceuticals Gmbh Pharmaceutical compositions comprising NEP-inhibitors, inhibitors of the endogenous endothelin producing system and diuretics
US20070292503A1 (en) * 2006-06-16 2007-12-20 Gorissen Henricus R Oral pharmaceutical composition of poorly water-soluble active substance
US20070299054A1 (en) * 2006-06-22 2007-12-27 Rajesh Jain Oral pharmaceutical composition of a poorly water-soluble active agent
KR20100135729A (ko) * 2008-01-31 2010-12-27 반더빌트유니버시티 폐의 용태에 따른 치료 방법

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0254032A3 (en) * 1986-06-20 1990-09-05 Schering Corporation Neutral metalloendopeptidase inhibitors in the treatment of hypertension
US4749688A (en) * 1986-06-20 1988-06-07 Schering Corporation Use of neutral metalloendopeptidase inhibitors in the treatment of hypertension
CA1337400C (en) * 1987-06-08 1995-10-24 Norma G. Delaney Inhibitors of neutral endopeptidase
US5362727A (en) * 1993-07-26 1994-11-08 Bristol-Myers Squibb Substituted azepino[2,1-a]isoquinoline compounds
DE19510566A1 (de) * 1995-03-23 1996-09-26 Kali Chemie Pharma Gmbh Benzazepin-, Benzoxazepin- und Benzothiazepin-N-essigsäurederivate sowie Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE19638020A1 (de) * 1996-09-18 1998-03-19 Solvay Pharm Gmbh Die gastrointestinale Durchblutung fördernde Arzneimittel

Also Published As

Publication number Publication date
CZ20012672A3 (cs) 2002-02-13
IL144622A (en) 2006-08-20
BR0008260A (pt) 2001-11-06
CN1198619C (zh) 2005-04-27
ZA200105828B (en) 2002-07-15
PT1154777E (pt) 2005-07-29
PL195283B1 (pl) 2007-08-31
KR20010101922A (ko) 2001-11-15
DZ3014A1 (fr) 2004-03-27
HUP0105491A2 (en) 2002-06-29
PL350167A1 (en) 2002-11-18
NO20013958L (no) 2001-10-15
ATE295174T1 (de) 2005-05-15
JP2002537258A (ja) 2002-11-05
AU2547600A (en) 2000-09-04
CA2362273C (en) 2010-05-25
CZ301499B6 (cs) 2010-03-24
HK1042247B (zh) 2005-09-23
CN1339966A (zh) 2002-03-13
UA63032C2 (en) 2004-01-15
HK1042247A1 (en) 2002-08-09
HUP0105491A3 (en) 2002-08-28
US6482820B2 (en) 2002-11-19
NO329588B1 (no) 2010-11-15
AU773240B2 (en) 2004-05-20
NO20013958D0 (no) 2001-08-15
US20020052361A1 (en) 2002-05-02
KR100797665B1 (ko) 2008-01-23
ES2238268T3 (es) 2005-09-01
EP1154777A1 (de) 2001-11-21
WO2000048601A1 (de) 2000-08-24
CA2362273A1 (en) 2000-08-24
AU773240C (en) 2004-11-18
NZ514058A (en) 2001-09-28
SK287254B6 (sk) 2010-04-07
SK10822001A3 (sk) 2002-03-05
DE19906310A1 (de) 2000-08-17
RU2270679C2 (ru) 2006-02-27
AR036864A1 (es) 2004-10-13
DE50010284D1 (de) 2005-06-16
TWI221770B (en) 2004-10-11
EP1154777B1 (de) 2005-05-11
KR20070027719A (ko) 2007-03-09

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