TR199902383T2 - Yeni pirimidin türevleri ve bunlarin hazirlanmasi için proses. - Google Patents

Yeni pirimidin türevleri ve bunlarin hazirlanmasi için proses.

Info

Publication number
TR199902383T2
TR199902383T2 TR1999/02383T TR9902383T TR199902383T2 TR 199902383 T2 TR199902383 T2 TR 199902383T2 TR 1999/02383 T TR1999/02383 T TR 1999/02383T TR 9902383 T TR9902383 T TR 9902383T TR 199902383 T2 TR199902383 T2 TR 199902383T2
Authority
TR
Turkey
Prior art keywords
pyrimidine derivatives
preparation
new pyrimidine
new
intermediates
Prior art date
Application number
TR1999/02383T
Other languages
English (en)
Inventor
Wook Lee Jong
Yong Lee Bong
Seop Kim Chang
Kyu Lee Seung
Seog Song Keun
Jin Lee Song
Jeon Shim Woo
Soon Hwang Man
Original Assignee
Yuhan Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yuhan Corporation filed Critical Yuhan Corporation
Publication of TR199902383T2 publication Critical patent/TR199902383T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Abstract

Bu bulus, mükemmel bir anti-salgilama faaliyeti olan yeni pirimidin türevleri ya da bunlarin farmasötik olarak kabul edilebilir tuzlari, bunlari aktif madde olarak içeren farmasötik terkipler, bunlarin yeni ara maddeleri ve hazirlanma prosesleri ile ilgilidir.
TR1999/02383T 1997-03-27 1998-03-24 Yeni pirimidin türevleri ve bunlarin hazirlanmasi için proses. TR199902383T2 (tr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR19970010862 1997-03-27
KR19970010863 1997-03-27
PCT/KR1998/000058 WO1998043968A1 (en) 1997-03-27 1998-03-24 Novel pyrimidine derivatives and processes for the preparation thereof

Publications (1)

Publication Number Publication Date
TR199902383T2 true TR199902383T2 (tr) 2000-06-21

Family

ID=26632616

Family Applications (1)

Application Number Title Priority Date Filing Date
TR1999/02383T TR199902383T2 (tr) 1997-03-27 1998-03-24 Yeni pirimidin türevleri ve bunlarin hazirlanmasi için proses.

Country Status (22)

Country Link
US (1) US6352993B1 (tr)
EP (1) EP1015444B1 (tr)
JP (1) JP3176379B2 (tr)
KR (1) KR100278857B1 (tr)
CN (1) CN1118464C (tr)
AR (1) AR012181A1 (tr)
AT (1) ATE241613T1 (tr)
AU (1) AU720385B2 (tr)
BR (1) BR9808070A (tr)
CA (1) CA2284795C (tr)
DE (1) DE69815126T2 (tr)
DK (1) DK1015444T3 (tr)
ES (1) ES2200324T3 (tr)
HK (1) HK1026418A1 (tr)
HU (1) HUP0000851A3 (tr)
IN (1) IN188411B (tr)
PT (1) PT1015444E (tr)
RU (1) RU2203894C2 (tr)
TR (1) TR199902383T2 (tr)
TW (1) TW542831B (tr)
UY (1) UY24938A1 (tr)
WO (1) WO1998043968A1 (tr)

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US6852739B1 (en) 1999-02-26 2005-02-08 Nitromed Inc. Methods using proton pump inhibitors and nitric oxide donors
TW200302728A (en) 2002-02-01 2003-08-16 Novartis Ag Substituted amines as IgE inhibitors
EP1534278A4 (en) 2002-08-01 2006-09-06 Nitromed Inc NITROSED PROTONATE PUMP INHIBITORS, COMPOSITIONS AND USE METHOD
JP2006528640A (ja) * 2003-07-22 2006-12-21 ニューロジェン・コーポレーション 置換ピリジン−２−イルアミン類縁体
AU2004283751B2 (en) * 2003-10-24 2011-05-19 Exelixis, Inc. p70S6 kinase modulators and method of use
CN1874772A (zh) 2003-11-03 2006-12-06 阿斯利康(瑞典)有限公司 治疗隐匿性胃食管反流的咪唑并[1,2－a]吡啶衍生物
KR101122376B1 (ko) * 2005-03-09 2012-03-26 주식회사유한양행 신규의 5,6-다이메틸피리미딘 유도체 및 그의 제조방법
EP1940804A2 (en) * 2005-10-14 2008-07-09 NeuroSearch A/S Novel pyrimidine-2,4-diamine derivatives and their use as modulators of small-conductance calcium-activated potassium channels
US8367684B2 (en) * 2007-06-13 2013-02-05 Valeant Pharmaceuticals International Derivatives of 4-(N-azacycloalkyl) anilides as potassium channel modulators
WO2010016490A1 (ja) 2008-08-05 2010-02-11 第一三共株式会社 イミダゾピリジン－２－オン誘導体
GB0908394D0 (en) 2009-05-15 2009-06-24 Univ Leuven Kath Novel viral replication inhibitors
GB0913636D0 (en) 2009-08-05 2009-09-16 Univ Leuven Kath Novel viral replication inhibitors
CA2817165A1 (en) 2010-11-15 2012-05-24 Patrick Chaltin Novel antiviral compounds
PL2678332T3 (pl) 2011-02-25 2016-12-30 Pochodne diaminopirymidyny i sposoby ich wytwarzania
RU2014137448A (ru) * 2012-02-17 2016-04-10 Эббви Инк. Диаминопиримидины, пригодные в качестве ингибиторов респираторно-синцитиального вируса человека (rsv)
IN2014MN02314A (tr) 2012-05-29 2015-08-07 Momentive Performance Mat Inc
SG10201600149VA (en) 2012-11-21 2016-02-26 Ptc Therapeutics Inc Substituted reverse pyrimidine bmi-1 inhibitors
KR20150130491A (ko) 2013-03-13 2015-11-23 제넨테크, 인크. 피라졸로 화합물 및 그것의 용도
EP3039015B1 (en) 2013-08-30 2019-10-30 PTC Therapeutics, Inc. Substituted pyrimidine bmi-1 inhibitors
EP3055301B1 (en) 2013-10-07 2019-11-20 Kadmon Corporation, LLC (2-(5-isoindolin-2-yl)pyrimidin-4-yl)-amine derivatives as rho kinase inhibitors for treating autoimmune diseases
WO2015076800A1 (en) 2013-11-21 2015-05-28 Ptc Therapeutics, Inc. Substituted pyridine and pyrazine bmi-1 inhibitors
EP3209299A4 (en) * 2014-10-22 2018-04-04 The Board of Regents of The University of Texas System Small-molecule inhibitors targeting discoidin domain receptor 1 and uses thereof
CN105669642B (zh) * 2014-11-19 2020-06-09 江苏天士力帝益药业有限公司 一种盐酸洛氟普啶的制备方法
SG11201804789QA (en) * 2016-01-04 2018-07-30 ObsEva SA Alpha-amino esters of hydroxypropylthiazolidine carboxamide derivative and salt form, crystal polymorph thereof
CN110461833A (zh) * 2017-04-05 2019-11-15 拜耳作物科学股份公司 2-氨基-5-氧基烷基嘧啶衍生物及其用于防治不希望的植物生长的用途
CN114685369B (zh) * 2022-05-17 2024-02-02 河南省科学院高新技术研究中心 一种利用离子液体制备1-甲基-1,2,3,4-四氢异喹啉的方法

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GB8621425D0 (en) * 1986-09-05 1986-10-15 Smith Kline French Lab Compounds
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PT900214E (pt) * 1996-05-04 2002-03-28 Yuhan Corp Processo para a preparacao de derivados da pirimidina

Also Published As

Publication number Publication date
DK1015444T3 (da) 2003-08-18
CN1251586A (zh) 2000-04-26
AU6523998A (en) 1998-10-22
HK1026418A1 (en) 2000-12-15
DE69815126D1 (de) 2003-07-03
KR100278857B1 (ko) 2001-01-15
KR19980080789A (ko) 1998-11-25
WO1998043968A1 (en) 1998-10-08
EP1015444A1 (en) 2000-07-05
UY24938A1 (es) 2001-01-31
JP3176379B2 (ja) 2001-06-18
CN1118464C (zh) 2003-08-20
AR012181A1 (es) 2000-09-27
JP2000513014A (ja) 2000-10-03
CA2284795A1 (en) 1998-10-08
US6352993B1 (en) 2002-03-05
PT1015444E (pt) 2003-10-31
CA2284795C (en) 2004-01-20
ES2200324T3 (es) 2004-03-01
IN188411B (tr) 2002-09-21
EP1015444B1 (en) 2003-05-28
RU2203894C2 (ru) 2003-05-10
BR9808070A (pt) 2000-03-08
HUP0000851A3 (en) 2002-04-29
DE69815126T2 (de) 2004-04-08
HUP0000851A1 (hu) 2001-04-28
ATE241613T1 (de) 2003-06-15
TW542831B (en) 2003-07-21
AU720385B2 (en) 2000-06-01

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