TR199801713T2 - Yeni eritromisin türevleri, bunlarin hazirlanmasina yönelik metodlar - Google Patents

Yeni eritromisin türevleri, bunlarin hazirlanmasina yönelik metodlar

Info

Publication number
TR199801713T2
TR199801713T2 TR1998/01713T TR9801713T TR199801713T2 TR 199801713 T2 TR199801713 T2 TR 199801713T2 TR 1998/01713 T TR1998/01713 T TR 1998/01713T TR 9801713 T TR9801713 T TR 9801713T TR 199801713 T2 TR199801713 T2 TR 199801713T2
Authority
TR
Turkey
Prior art keywords
preparation
methods
erythromycin derivatives
new erythromycin
formula
Prior art date
Application number
TR1998/01713T
Other languages
English (en)
Inventor
Agouridas Constantin
Chantot Jeon-Fran�Ois
Original Assignee
Hoechst Marion Roussel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel filed Critical Hoechst Marion Roussel
Publication of TR199801713T2 publication Critical patent/TR199801713T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

x'in bir CH2 veya SO2 radikali veya bir oksijen atomu, Y'nin bir (CH2)m-(CH=CH)n(CH2)o radikali,ve burada m+n+o <8, n = 0 veya 1'dir, Ar'nin bir aril radikali ve W'nin de hidrojen atomu veya bir karbamat fonksiyonu bakiyesi oldugu formül (I)'i havi bilesikler tarif edilmektedir. Formül (I)'i havi bilesikler degerli antibiyotik özellikleri sahiptir. FORMÜL.
TR1998/01713T 1996-02-28 1997-02-27 Yeni eritromisin türevleri, bunlarin hazirlanmasina yönelik metodlar TR199801713T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9602472A FR2745290B1 (fr) 1996-02-28 1996-02-28 Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments

Publications (1)

Publication Number Publication Date
TR199801713T2 true TR199801713T2 (tr) 1998-12-21

Family

ID=9489659

Family Applications (1)

Application Number Title Priority Date Filing Date
TR1998/01713T TR199801713T2 (tr) 1996-02-28 1997-02-27 Yeni eritromisin türevleri, bunlarin hazirlanmasina yönelik metodlar

Country Status (31)

Country Link
US (1) US6096714A (tr)
EP (1) EP0885234B1 (tr)
JP (1) JP4102440B2 (tr)
KR (1) KR100486053B1 (tr)
CN (1) CN1168734C (tr)
AP (1) AP952A (tr)
AR (1) AR005999A1 (tr)
AT (1) ATE217633T1 (tr)
AU (1) AU716204B2 (tr)
BG (1) BG63207B1 (tr)
BR (1) BR9707709B1 (tr)
CZ (1) CZ293893B6 (tr)
DE (1) DE69712610T2 (tr)
DK (1) DK0885234T3 (tr)
EA (1) EA001376B1 (tr)
EE (1) EE9800265A (tr)
ES (1) ES2176698T3 (tr)
FR (1) FR2745290B1 (tr)
HU (1) HU227567B1 (tr)
IL (1) IL125622A (tr)
NO (1) NO983955D0 (tr)
NZ (1) NZ331600A (tr)
OA (1) OA10845A (tr)
PL (1) PL191736B1 (tr)
PT (1) PT885234E (tr)
SK (1) SK118498A3 (tr)
TR (1) TR199801713T2 (tr)
UA (1) UA58504C2 (tr)
WO (1) WO1997031929A1 (tr)
YU (1) YU37098A (tr)
ZA (1) ZA971659B (tr)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA989835B (en) * 1997-10-29 1999-05-05 Taisho Pharmaceutical Co Ltd Erythromycin a derivatives
JP2004514643A (ja) * 1997-10-29 2004-05-20 大正製薬株式会社 エリスロマイシンａ誘導体
FR2792637B1 (fr) * 1999-04-26 2001-06-01 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
JP4573925B2 (ja) * 1998-07-09 2010-11-04 アベンティス・ファーマ・ソシエテ・アノニム 新規のエリスロマイシン誘導体、その製造方法及びその薬剤としての使用
FR2780977B1 (fr) * 1998-07-09 2000-09-01 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2781484B1 (fr) 1998-07-21 2001-08-10 Hoechst Marion Roussel Inc Nouveaux derives de la 6-deoxy erythromycine, leur procede de preparation et leur application comme medicaments
HUP0105190A3 (en) 1999-01-27 2003-03-28 Pfizer Prod Inc Ketolide antibiotics, medicaments containing them and their use
JP2003500414A (ja) * 1999-05-24 2003-01-07 ファイザー・プロダクツ・インク １３−メチルエリスロマイシン誘導体
AU6183800A (en) * 1999-08-06 2001-03-05 Taisho Pharmaceutical Co., Ltd. Erythromycin a derivatives
AU6316400A (en) * 1999-08-06 2001-03-05 Taisho Pharmaceutical Co., Ltd. Erythromycin a derivatives
WO2001010878A1 (fr) * 1999-08-06 2001-02-15 Taisho Pharmaceutical Co., Ltd. Derives d'erythromycine a
EP1146051A3 (en) * 2000-04-10 2001-10-31 Pfizer Products Inc. Erythromycin A derivatives
US20020115621A1 (en) * 2000-08-07 2002-08-22 Wei-Gu Su Macrolide antibiotics
ITMI20021726A1 (it) * 2002-08-01 2004-02-02 Zambon Spa Macrolidi ad attivita' antiinfiammatoria.
US7601695B2 (en) 2003-03-10 2009-10-13 Optimer Pharmaceuticals, Inc. Antibacterial agents
WO2005007143A2 (en) * 2003-07-14 2005-01-27 The Board Of Trustees Of The University Of Illinois Use of makrolides and ketolides for the treatment of tuberculosis
WO2007069264A2 (en) * 2005-12-15 2007-06-21 Alembic Limited Reference standards for determining the purity of telithromycin and processes therefor
WO2009055557A1 (en) 2007-10-25 2009-04-30 Cempra Pharmaceuticals, Inc. Process for the preparation of macrolide antibacterial agents
US8796232B2 (en) 2008-10-24 2014-08-05 Cempra Pharmaceuticals, Inc. Methods for treating resistant diseases using triazole containing macrolides
US9937194B1 (en) 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
JP5914335B2 (ja) 2009-09-10 2016-05-11 センプラ ファーマシューティカルズ，インコーポレイテッド マラリア、結核、及びｍａｃ病の治療方法
WO2011119604A1 (en) 2010-03-22 2011-09-29 Cempra Pharmaceuticals, Inc. Crystalline forms of a macrolide, and uses therefor
BR112012029586A2 (pt) 2010-05-20 2016-08-02 Cempra Pharmaceuticals Inc processos para preparar macrolídeos e cetolídeos e intermediários dos mesmos
KR20180110181A (ko) 2010-09-10 2018-10-08 셈프라 파마슈티컬스, 인크. 질환을 치료하기 위한 수소결합 형성 플루오로 케토라이드
CA2868262A1 (en) 2012-03-27 2013-10-03 Cempra Pharmaceuticals, Inc. Parenteral formulations for administering macrolide antibiotics
CN105163785A (zh) 2013-03-14 2015-12-16 森普拉制药公司 用于治疗呼吸道疾病的方法及其制剂
CA2907085A1 (en) 2013-03-15 2014-09-18 Cempra Pharmaceuticals, Inc. Convergent processes for preparing macrolide antibacterial agents

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US487411A (en) * 1892-12-06 Island
IL114589A (en) * 1990-11-21 1999-12-22 Roussel Uclaf Intermediates for the preparation of the history of erythromycin
US5444031A (en) * 1993-01-21 1995-08-22 Calgon Carbon Corporation Process for making catalytic carbon
FR2727969B1 (fr) * 1994-12-09 1997-01-17 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments

Also Published As

Publication number Publication date
BG63207B1 (bg) 2001-06-29
US6096714A (en) 2000-08-01
BR9707709A (pt) 1999-04-06
JP4102440B2 (ja) 2008-06-18
KR19990087324A (ko) 1999-12-27
PT885234E (pt) 2002-10-31
NO983955L (no) 1998-08-27
HUP9902576A1 (hu) 1999-12-28
WO1997031929A1 (fr) 1997-09-04
HUP9902576A3 (en) 2001-03-28
OA10845A (fr) 2003-02-05
EP0885234A1 (fr) 1998-12-23
EA001376B1 (ru) 2001-02-26
PL328608A1 (en) 1999-02-01
ATE217633T1 (de) 2002-06-15
FR2745290B1 (fr) 1998-04-03
ZA971659B (en) 1998-02-26
BR9707709B1 (pt) 2014-10-14
CN1212700A (zh) 1999-03-31
ES2176698T3 (es) 2002-12-01
DE69712610T2 (de) 2002-11-28
AP9801318A0 (en) 1998-09-30
AR005999A1 (es) 1999-07-21
DK0885234T3 (da) 2002-08-26
CZ293893B6 (cs) 2004-08-18
PL191736B1 (pl) 2006-06-30
EP0885234B1 (fr) 2002-05-15
FR2745290A1 (fr) 1997-08-29
BG102691A (en) 1999-06-30
AU1929897A (en) 1997-09-16
NZ331600A (en) 1999-08-30
AP952A (en) 2001-03-29
EE9800265A (et) 1999-02-15
CN1168734C (zh) 2004-09-29
IL125622A0 (en) 1999-04-11
UA58504C2 (uk) 2003-08-15
EA199800768A1 (ru) 1999-02-25
HU227567B1 (en) 2011-08-29
AU716204B2 (en) 2000-02-24
IL125622A (en) 2003-10-31
CZ258798A3 (cs) 1998-12-16
JP2000505469A (ja) 2000-05-09
KR100486053B1 (ko) 2005-06-16
SK118498A3 (en) 1999-07-12
DE69712610D1 (de) 2002-06-20
NO983955D0 (no) 1998-08-27
YU37098A (sh) 1999-07-28

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