TR199600970A2 - CDCH'nin yeni kristal modifikasyonu, bunun hazirlanmasi icin bir islem ve bu modifikasyonu iceren farmasotik formülasyonlar. - Google Patents

CDCH'nin yeni kristal modifikasyonu, bunun hazirlanmasi icin bir islem ve bu modifikasyonu iceren farmasotik formülasyonlar.

Info

Publication number
TR199600970A2
TR199600970A2 TR96/00970A TR9600970A TR199600970A2 TR 199600970 A2 TR199600970 A2 TR 199600970A2 TR 96/00970 A TR96/00970 A TR 96/00970A TR 9600970 A TR9600970 A TR 9600970A TR 199600970 A2 TR199600970 A2 TR 199600970A2
Authority
TR
Turkey
Prior art keywords
modification
cdch
preparation
pharmaceutical formulations
formulations containing
Prior art date
Application number
TR96/00970A
Other languages
English (en)
Turkish (tr)
Inventor
Dr Alfons Grunenberg
Dr Patrick Bosche
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7779831&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TR199600970(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of TR199600970A2 publication Critical patent/TR199600970A2/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
TR96/00970A 1995-12-12 1996-12-05 CDCH'nin yeni kristal modifikasyonu, bunun hazirlanmasi icin bir islem ve bu modifikasyonu iceren farmasotik formülasyonlar. TR199600970A2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19546249A DE19546249A1 (de) 1995-12-12 1995-12-12 Neue Kristallmodifikation des 1-Cyclopropyl-7-([S,S]-2,8-diazabicyclo[4,3,0]non-8-yl)-6-fluor-1,4-dihydro-8-methoxy-4-oxo-3-chinolincarbonsäure Hydrochlorid (CDCH), Verfahren zu dessen Herstellung und diese enthaltende pharmazeutische Zubereitungen

Publications (1)

Publication Number Publication Date
TR199600970A2 true TR199600970A2 (tr) 1997-06-21

Family

ID=7779831

Family Applications (1)

Application Number Title Priority Date Filing Date
TR96/00970A TR199600970A2 (tr) 1995-12-12 1996-12-05 CDCH'nin yeni kristal modifikasyonu, bunun hazirlanmasi icin bir islem ve bu modifikasyonu iceren farmasotik formülasyonlar.

Country Status (42)

Country Link
US (1) US5849752A (OSRAM)
EP (1) EP0780390B1 (OSRAM)
JP (1) JP4104687B2 (OSRAM)
KR (1) KR100525146B1 (OSRAM)
CN (1) CN1061348C (OSRAM)
AR (1) AR005009A1 (OSRAM)
AT (1) ATE221531T1 (OSRAM)
AU (1) AU708006B2 (OSRAM)
BG (1) BG62258B1 (OSRAM)
BR (1) BR9605968A (OSRAM)
CA (1) CA2192418C (OSRAM)
CO (1) CO4480105A1 (OSRAM)
CU (1) CU22774A3 (OSRAM)
CZ (1) CZ288657B6 (OSRAM)
DE (2) DE19546249A1 (OSRAM)
DK (1) DK0780390T3 (OSRAM)
EE (1) EE03474B1 (OSRAM)
ES (1) ES2179910T3 (OSRAM)
HR (1) HRP960558B1 (OSRAM)
HU (1) HU226521B1 (OSRAM)
ID (1) ID22625A (OSRAM)
IL (1) IL119795A (OSRAM)
IN (1) IN185805B (OSRAM)
MA (1) MA24342A1 (OSRAM)
MY (1) MY117492A (OSRAM)
NL (1) NL300109I1 (OSRAM)
NO (1) NO306725B1 (OSRAM)
NZ (1) NZ299905A (OSRAM)
PL (1) PL184885B1 (OSRAM)
PT (1) PT780390E (OSRAM)
RO (1) RO119782B1 (OSRAM)
RU (1) RU2162468C2 (OSRAM)
SA (1) SA96170492B1 (OSRAM)
SG (1) SG47201A1 (OSRAM)
SI (1) SI0780390T1 (OSRAM)
SK (1) SK282805B6 (OSRAM)
SV (1) SV1996000109A (OSRAM)
TR (1) TR199600970A2 (OSRAM)
TW (1) TW411340B (OSRAM)
UA (1) UA35638C2 (OSRAM)
YU (1) YU49485B (OSRAM)
ZA (1) ZA9610405B (OSRAM)

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AU731693B2 (en) * 1997-09-25 2001-04-05 Bayer Intellectual Property Gmbh Drug formulation having controlled release of active compound
DE19751948A1 (de) * 1997-11-24 1999-05-27 Bayer Ag Verfahren zur Herstellung von 8-Methoxy-Chinoloncarbonsäuren
US6395746B1 (en) 1998-09-30 2002-05-28 Alcon Manufacturing, Ltd. Methods of treating ophthalmic, otic and nasal infections and attendant inflammation
US6716830B2 (en) 1998-09-30 2004-04-06 Alcon, Inc. Ophthalmic antibiotic compositions containing moxifloxacin
US6509327B1 (en) 1998-09-30 2003-01-21 Alcon Manufacturing, Ltd. Compositions and methods for treating otic, ophthalmic and nasal infections
ES2229786T3 (es) * 1998-11-10 2005-04-16 Bayer Healthcare Ag Preparacion farmaceutica de moxifloxacina.
DE19854357A1 (de) * 1998-11-25 2000-05-31 Bayer Ag Semi-Hydrochlorid von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo/4.3.0/ -nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19854355A1 (de) * 1998-11-25 2000-05-31 Bayer Ag Kristallmodifikation B von 8-Cyan-1-cyclopropyl-7-(1S, 6S-2,8-diazabicyclo-/4.3.O/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19854356A1 (de) * 1998-11-25 2000-05-31 Bayer Ag Kristallmodifikation A von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo-/4.3.0/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19908449A1 (de) * 1999-02-26 2000-08-31 Bayer Ag Kristallmodifikation C von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicylo-[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chino/incarbonsäure
EP1562942A1 (en) * 2002-10-31 2005-08-17 Ranbaxy Laboratories, Ltd. Amorphous moxifloxacin hydrochloride
ES2332367T5 (es) * 2003-04-09 2013-12-17 Dr. Reddy's Laboratories Ltd. Forma cristalina III de clorhidrato de moxifloxacina anhidro y su procedimiento de preparación
US20060264635A1 (en) * 2003-08-05 2006-11-23 Chava Satyanarayana Process for the preparation of moxifloxacin hydrochloride
ITMI20032259A1 (it) 2003-11-20 2005-05-21 Chemi Spa Nuovo polimorfo dell'acido 1-ciclopropil-7-(s,s-2,8-diazabciclo-4.3.0-non-8-il)-6-fluoro-1,4-diidro-8-metossi-4-oxo-chinolin carbossilico cloridrato e metodi per la sua preparazione
EP1685130B1 (en) * 2003-11-20 2008-12-10 CHEMI S.p.A. Polymorphs of 1-cyclopropyl-7-([s,s] - 2,8-diazadicyclo [4.3.0] non-8-yl) -6-fluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinoline carboxylic acid hydrochloride and methods for the preparation thereof
US7491725B2 (en) 2004-02-06 2009-02-17 Bristol-Myers Squibb Company Process for preparing 2-aminothiazole-5-aromatic carboxamides as kinase inhibitors
DE102004015981A1 (de) * 2004-04-01 2005-10-20 Bayer Healthcare Ag Neue kirstalline Form von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE102004063347A1 (de) * 2004-12-23 2006-07-13 Stada Arzneimittel Ag Gebrauchsfertige Gemcitabinlösungen und Gemcitabinlösungskonzentrate
WO2007033515A1 (fr) * 2005-09-21 2007-03-29 Shenzhen Tys R & D Co., Ltd. Formulation orale contenant de la moxifloxacine et son procédé de préparation
GB0612422D0 (en) * 2006-06-23 2006-08-02 Generics Uk Ltd Novel hydrate form
WO2008000418A2 (en) 2006-06-27 2008-01-03 Sandoz Ag New method for salt preparation
ES2303768B1 (es) * 2006-09-08 2009-06-05 Quimica Sintetica, S.A. Nueva forma cristalina de moxifloxacino clorhidrato.
KR101539561B1 (ko) * 2006-11-13 2015-07-27 씨아이피엘에이 엘티디. 목시플록사신 염산염의 합성방법
EP1992626A1 (en) * 2007-05-10 2008-11-19 Sandoz AG Process for the preparation of moxifloxacin hydrochloride
EP2083010A1 (en) * 2008-01-08 2009-07-29 Chemo Ibérica, S.A. Polymorphic Forms of Moxifloxacin hydrochloride and processes for preparation thereof
EP2154137A1 (en) 2008-08-04 2010-02-17 Chemo Ibérica, S.A. Crystalline form of moxifloxacin base
WO2010041100A1 (en) 2008-10-09 2010-04-15 Abdi Ibrahim Ilac Sanayi Ve Ticaret Anonim Sirketi Using of organic solvents in wet granulation of moxifloxacin
EP2342204A1 (en) * 2008-11-06 2011-07-13 Hetero Research Foundation Novel polymorph of moxifloxacin hydrochloride
EP2837376A3 (de) 2008-12-08 2015-03-25 ratiopharm GmbH Kompaktiertes Moxifloxacin
KR20120025519A (ko) 2009-05-15 2012-03-15 레드엑스 파마 리미티드 산화환원 약물 유도체
WO2011121596A2 (en) * 2010-04-01 2011-10-06 Neuland Laboratories Ltd. Crystal modification of moxifloxacin hydrochloride
BRPI1106900A2 (pt) 2011-12-26 2013-11-05 Ems Sa Composição farmacêutica sólida compreendendo antibótico da familia das quinolonas e processo de sua obtenção
FR2992218B1 (fr) 2012-06-22 2015-01-23 Rivopharm Sa Composition pharmaceutique de chlorhydrate de moxifloxacine et procede de preparation
CN102924449B (zh) * 2012-10-30 2015-08-12 重庆福安药业集团庆余堂制药有限公司 盐酸莫西沙星h晶型及其制备方法和药物组合物
EP2928892B1 (en) 2012-12-04 2018-03-21 Mankind Pharma Ltd. An improved process for the preparation of moxifloxacin hydrochloride
RU2561037C2 (ru) * 2013-02-07 2015-08-20 Открытое акционерное общество "Химико-фармацевтический комбинат "АКРИХИН" (ОАО "АКРИХИН") Антибактериальная фармацевтическая композиция и способ ее получения
EP2969004A4 (en) 2013-03-15 2016-09-21 Melinta Therapeutics Inc METHOD FOR THE TREATMENT OF INFECTIONS IN OVERWEIGHT AND ADIPOSIVE PATIENTS USING ANTIBIOTICS

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DE3601567A1 (de) * 1986-01-21 1987-07-23 Bayer Ag 7-(azabicycloalkyl)-chinoloncarbonsaeure- und -naphthyridon-carbonsaeure-derivate
CN1019114B (zh) * 1986-03-31 1992-11-18 三共株式会社 喹啉-3-羟酸衍生物的制备方法
AU609974B2 (en) * 1988-05-18 1991-05-09 Warner-Lambert Company Improved process for the preparation of 5-amino-7- (substituted amino)-quinoline-3-carboxylic acids
DE3910663A1 (de) * 1989-04-03 1990-10-04 Bayer Ag 5-alkylchinoloncarbonsaeuren
RO108347B1 (ro) * 1989-10-30 1994-04-28 Bellon Labor Sa Roger DERIVATI DE BENZO-(b)-NAFTIRIDIN-1,8 SI PROCEDEU DE PREPARARE A ACESTORA
TW209865B (OSRAM) 1992-01-10 1993-07-21 Bayer Ag
ATE207479T1 (de) * 1992-01-31 2001-11-15 Chugai Pharmaceutical Co Ltd Kristalle von derivaten von chinozon carbonsäure- hydraten
DE4234078A1 (de) * 1992-10-09 1994-04-14 Bayer Ag Chinoloncarbonsäuren
JP3268098B2 (ja) * 1992-12-25 2002-03-25 第一製薬株式会社 二環性環状アミン誘導体
ZA946853B (en) * 1993-09-10 1995-04-24 Daiichi Seiyaku Co Crystals of antimicrobial compound.
DE69504392T2 (de) * 1994-04-07 1999-02-11 Pfizer Inc., New York, N.Y. Verwendung von Trovafloxacin oder dessen Derivaten zur Herstellung eines Arzneimittels zur Behandlung von H.Pylori Infektionen

Also Published As

Publication number Publication date
ID22625A (id) 1999-12-02
ES2179910T3 (es) 2003-02-01
HUP9603428A2 (en) 1997-08-28
JP4104687B2 (ja) 2008-06-18
PL317415A1 (en) 1997-06-23
US5849752A (en) 1998-12-15
CN1061348C (zh) 2001-01-31
HRP960558A2 (en) 1998-02-28
CZ364696A3 (en) 1997-07-16
NO306725B1 (no) 1999-12-13
KR100525146B1 (ko) 2006-01-27
AU708006B2 (en) 1999-07-29
CU22774A3 (es) 2002-07-24
CO4480105A1 (es) 1997-07-09
AU7421696A (en) 1997-06-19
BG101043A (en) 1998-04-30
DE19546249A1 (de) 1997-06-19
EE9600201A (et) 1997-06-16
HU9603428D0 (en) 1997-01-28
MY117492A (en) 2004-07-31
TW411340B (en) 2000-11-11
NL300109I1 (nl) 2003-02-03
PL184885B1 (pl) 2003-01-31
BR9605968A (pt) 1998-08-18
IL119795A (en) 1998-12-27
MA24342A1 (fr) 1998-07-01
CZ288657B6 (cs) 2001-08-15
KR970042550A (ko) 1997-07-24
JPH09169757A (ja) 1997-06-30
YU65096A (sh) 1998-12-23
UA35638C2 (uk) 2001-04-16
CN1160052A (zh) 1997-09-24
CA2192418C (en) 2001-06-12
YU49485B (sh) 2006-08-17
EP0780390B1 (de) 2002-07-31
DK0780390T3 (da) 2002-11-11
SV1996000109A (es) 1997-10-23
SG47201A1 (en) 1998-03-20
NZ299905A (en) 1998-09-24
HRP960558B1 (en) 2002-04-30
RU2162468C2 (ru) 2001-01-27
PT780390E (pt) 2002-11-29
HUP9603428A3 (en) 1997-10-28
IL119795A0 (en) 1997-03-18
SA96170492B1 (ar) 2006-05-23
SI0780390T1 (en) 2002-10-31
AR005009A1 (es) 1999-04-07
CA2192418A1 (en) 1997-06-13
DE59609501D1 (de) 2002-09-05
IN185805B (OSRAM) 2001-05-05
SK159196A3 (en) 1997-10-08
NO965298D0 (no) 1996-12-11
NO965298L (no) 1997-06-13
MX9606325A (es) 1997-10-31
ATE221531T1 (de) 2002-08-15
BG62258B1 (bg) 1999-06-30
EE03474B1 (et) 2001-08-15
ZA9610405B (en) 1997-06-23
RO119782B1 (ro) 2005-03-30
EP0780390A1 (de) 1997-06-25
SK282805B6 (sk) 2002-12-03
HU226521B1 (en) 2009-03-30

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