TNSN88096A1 - Nouveau n-(1-alkyl-3-hydroxy-4-piperidyl) - Google Patents
Nouveau n-(1-alkyl-3-hydroxy-4-piperidyl)Info
- Publication number
- TNSN88096A1 TNSN88096A1 TNTNSN88096A TNSN88096A TNSN88096A1 TN SN88096 A1 TNSN88096 A1 TN SN88096A1 TN TNSN88096 A TNTNSN88096 A TN TNSN88096A TN SN88096 A TNSN88096 A TN SN88096A TN SN88096 A1 TNSN88096 A1 TN SN88096A1
- Authority
- TN
- Tunisia
- Prior art keywords
- piperidyl
- hydroxy
- alkyl
- new
- motility
- Prior art date
Links
- 210000005095 gastrointestinal system Anatomy 0.000 abstract 2
- 230000004899 motility Effects 0.000 abstract 2
- 241001465754 Metazoa Species 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 229940054066 benzamide antipsychotics Drugs 0.000 abstract 1
- 150000003936 benzamides Chemical class 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000004936 stimulating effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/42—Oxygen atoms attached in position 3 or 5
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Nutrition Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
L'INVENTION CONCERNE DES N-(1-ALKYL-3- HYDROXY-4-PIPERIDYL) BENZAMIDES SUBSTITUES, LES N-OXYDES, LES SELS D'ADDITION D'ACIDES CONVENANT EN PHARMACIE ET LES FORMES ISOMERES STEREOCHIMIQUES CORRESPONDANTS QUI SONT UTILES COMME MEDICAMENTS, NOTAMMENT POUR STIMULER LA MOTILITE DU SYSTEME GASTRO-INTESTINAL, UN PROCEDE POUR LEUR PREPARATION ET UN PROCEDE DE TRAITEMENT D'ANIMAUX A SANG CHAUD ATTEINTS DE TROUBLES DE LA MOTILITE DU SYSTEME GASTRO- INTESTINAL LES UTILISANT
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10111587A | 1987-09-25 | 1987-09-25 |
Publications (1)
Publication Number | Publication Date |
---|---|
TNSN88096A1 true TNSN88096A1 (fr) | 1990-07-10 |
Family
ID=22283104
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TNTNSN88096A TNSN88096A1 (fr) | 1987-09-25 | 1988-09-23 | Nouveau n-(1-alkyl-3-hydroxy-4-piperidyl) |
Country Status (24)
Country | Link |
---|---|
EP (1) | EP0309043B1 (fr) |
JP (1) | JP2830936B2 (fr) |
KR (1) | KR0124054B1 (fr) |
CN (2) | CN1021652C (fr) |
AT (1) | ATE113936T1 (fr) |
AU (1) | AU610241B2 (fr) |
BG (1) | BG60560B1 (fr) |
CA (1) | CA1317940C (fr) |
DE (1) | DE3852085T2 (fr) |
DK (1) | DK529888A (fr) |
ES (1) | ES2066781T3 (fr) |
FI (1) | FI94129C (fr) |
GR (1) | GR3014972T3 (fr) |
HU (1) | HU203724B (fr) |
IE (1) | IE64980B1 (fr) |
IL (1) | IL87847A0 (fr) |
MA (1) | MA21381A1 (fr) |
NO (1) | NO172580C (fr) |
NZ (1) | NZ226125A (fr) |
PH (1) | PH25504A (fr) |
PT (1) | PT88577B (fr) |
SU (1) | SU1625331A3 (fr) |
TN (1) | TNSN88096A1 (fr) |
ZA (1) | ZA887157B (fr) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ225152A (en) * | 1987-07-17 | 1990-04-26 | Janssen Pharmaceutica Nv | Heterocyclically substituted piperidinyl benzamides as pharmaceuticals |
US5019583A (en) * | 1989-02-15 | 1991-05-28 | Glaxo Inc. | N-phenyl-N-(4-piperidinyl)amides useful as analgesics |
US5374637A (en) * | 1989-03-22 | 1994-12-20 | Janssen Pharmaceutica N.V. | N-(3-hydroxy-4-piperidinyl)(dihydrobenzofuran, dihydro-2H-benzopyran or dihydrobenzodioxin)carboxamide derivatives |
GB9005014D0 (en) | 1990-03-06 | 1990-05-02 | Janssen Pharmaceutica Nv | N.(4.piperidinyl)(dihydrobenzofuran or dihydro.2h.benzopyran)carboxamide derivatives |
US5438064A (en) * | 1991-12-23 | 1995-08-01 | American Home Products Corporation | Derivatives of 4-anilinoquinoline-3-carboxamide as analgesic agents |
TW294595B (fr) * | 1992-11-20 | 1997-01-01 | Janssen Pharmaceutica Nv | |
JP3719612B2 (ja) * | 1993-06-14 | 2005-11-24 | 塩野義製薬株式会社 | ヘテロ環を含有する尿素誘導体 |
CA2200579C (fr) * | 1994-09-27 | 2006-07-04 | Georges Henri Paul Van Daele (Deceased) | Derives benzoates bicycliques de phenyl-oxo-alkyl-(4-piperidinyle) |
JP3953097B2 (ja) * | 1994-09-27 | 2007-08-01 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | N−置換ピペリジニル二環式ベンゾエート誘導体 |
US6096761A (en) * | 1996-02-15 | 2000-08-01 | Janssen Pharmaceutica N.V. | Esters of 3-hydroxy-piperidinemethanol derivatives |
NZ330263A (en) * | 1996-02-15 | 1999-06-29 | Janssen Pharmaceutica Nv | Esters of 3-hydroxy-piperidinemethanol derivatives to improve gastric emptying |
TW548103B (en) | 1997-07-11 | 2003-08-21 | Janssen Pharmaceutica Nv | Bicyclic benzamides of 3- or 4-substituted 4-(aminomethyl)-piperidine derivatives |
CN1076173C (zh) * | 1998-05-29 | 2001-12-19 | 孙国文 | 香身茶剂 |
TW570920B (en) * | 1998-12-22 | 2004-01-11 | Janssen Pharmaceutica Nv | 4-(aminomethyl)-piperidine benzamides for treating gastrointestinal disorders |
WO2001093849A2 (fr) * | 2000-06-07 | 2001-12-13 | Aryx Therapeutics | Materiaux et methodes permettant de traiter le reflux gastro-oesophagien |
GB0211230D0 (en) | 2002-05-16 | 2002-06-26 | Medinnova Sf | Treatment of heart failure |
US8524736B2 (en) | 2004-01-07 | 2013-09-03 | Armetheon, Inc. | Stereoisomeric compounds and methods for the treatment of gastrointestinal and central nervous system disorders |
US8138204B2 (en) | 2004-01-07 | 2012-03-20 | Aryx Therapeutics, Inc. | Stereoisomeric compounds and methods for the treatment of gastrointestinal and central nervous system disorders |
BRPI0506736B1 (pt) * | 2004-01-07 | 2018-08-21 | Renexxion Llc | Compostos estereoisoéricos para o tratamento de distúrbios gastrointestinais e no sistema nervoso central, e composições |
MY150958A (en) * | 2005-06-16 | 2014-03-31 | Astrazeneca Ab | Compounds for the treatment of multi-drug resistant bacterial infections |
CA2620379C (fr) | 2005-08-31 | 2015-02-24 | Aryx Therapeutics, Inc. | Methodes synthetiques et intermediaires de composes stereoisomeres utiles dans le traitement des troubles gastro-intestinaux et du systeme nerveux central |
US20080085915A1 (en) * | 2006-06-23 | 2008-04-10 | Cyrus Becker | Compounds and methods for the treatment of gastrointestinal and central nervous system disorders |
KR100976063B1 (ko) * | 2007-03-16 | 2010-08-17 | 동아제약주식회사 | 신규한 벤즈아미드 유도체 화합물 및 그의 제조방법 |
AU2010232727A1 (en) | 2009-03-31 | 2011-10-20 | Arqule, Inc. | Substituted heterocyclic compounds |
KR101815123B1 (ko) * | 2010-09-01 | 2018-01-04 | 얀센 파마슈티카 엔.브이. | 5ht2b 수용체 길항제 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1183847A (fr) * | 1981-10-01 | 1985-03-12 | Georges Van Daele | N-(3-hydroxy-4-piperidinyl)benzamide; derives |
US4634704A (en) * | 1983-10-06 | 1987-01-06 | Janssen Pharmaceutica, N.V. | Anti-allergic five membered heterocyclic ring containing N-(bicyclic heterocycyl)-4-piperidinamines |
ZW12187A1 (en) * | 1986-07-03 | 1989-02-01 | Janssen Pharmaceutica Nv | 4-(aroylamino)piperidinebutanamide derivatives |
NZ225152A (en) * | 1987-07-17 | 1990-04-26 | Janssen Pharmaceutica Nv | Heterocyclically substituted piperidinyl benzamides as pharmaceuticals |
-
1988
- 1988-09-06 CA CA000576546A patent/CA1317940C/fr not_active Expired - Fee Related
- 1988-09-09 NZ NZ226125A patent/NZ226125A/xx unknown
- 1988-09-15 AT AT88202011T patent/ATE113936T1/de not_active IP Right Cessation
- 1988-09-15 EP EP88202011A patent/EP0309043B1/fr not_active Expired - Lifetime
- 1988-09-15 DE DE3852085T patent/DE3852085T2/de not_active Expired - Fee Related
- 1988-09-15 ES ES88202011T patent/ES2066781T3/es not_active Expired - Lifetime
- 1988-09-19 AU AU22322/88A patent/AU610241B2/en not_active Ceased
- 1988-09-21 MA MA21626A patent/MA21381A1/fr unknown
- 1988-09-22 NO NO884208A patent/NO172580C/no unknown
- 1988-09-23 PH PH37582A patent/PH25504A/en unknown
- 1988-09-23 IE IE288988A patent/IE64980B1/en not_active IP Right Cessation
- 1988-09-23 BG BG85500A patent/BG60560B1/bg unknown
- 1988-09-23 SU SU884356607A patent/SU1625331A3/ru active
- 1988-09-23 FI FI884375A patent/FI94129C/fi not_active IP Right Cessation
- 1988-09-23 HU HU884991A patent/HU203724B/hu not_active IP Right Cessation
- 1988-09-23 PT PT88577A patent/PT88577B/pt not_active IP Right Cessation
- 1988-09-23 TN TNTNSN88096A patent/TNSN88096A1/fr unknown
- 1988-09-23 DK DK529888A patent/DK529888A/da not_active Application Discontinuation
- 1988-09-23 IL IL87847A patent/IL87847A0/xx not_active IP Right Cessation
- 1988-09-23 ZA ZA887157A patent/ZA887157B/xx unknown
- 1988-09-24 JP JP63237547A patent/JP2830936B2/ja not_active Expired - Lifetime
- 1988-09-24 CN CN88106959A patent/CN1021652C/zh not_active Expired - Fee Related
- 1988-09-27 KR KR1019880012475A patent/KR0124054B1/ko not_active IP Right Cessation
-
1992
- 1992-07-10 CN CN92105871A patent/CN1067889A/zh active Pending
-
1995
- 1995-02-08 GR GR940403606T patent/GR3014972T3/el unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
TNSN88096A1 (fr) | Nouveau n-(1-alkyl-3-hydroxy-4-piperidyl) | |
RU93058531A (ru) | Фторалкоксибензиламинные производные азотсодержащих гетероциклов, фармацевтическая композиция, способ лечения | |
UA41906C2 (uk) | Спосіб лікування неврологічних порушень, викликаних травмами | |
DK46789A (da) | 3-indolpyrodruesyrederivater og farmaceutisk anvendelse deraf | |
PT98393A (pt) | Processo para a preparacao de derivados de quinuclidina | |
DE69223965D1 (de) | Anticonvulsives aminosäurederivat | |
RU94016393A (ru) | Пептиды, обладающие способностью к стимулированию высвобождения гормона роста, способ получения, фармацевтическая композиция, способ лечения | |
UA19171A (uk) | Спосіб одержаhhя фіhілалкіламіhів або їх фармакологічhо прийhятhих солей | |
RU93058351A (ru) | Замещенные 3-аминохинуклидины, фармацевтические композиции на его основе, способы лечения, способ получения, промежуточные соединения | |
SE8302361D0 (sv) | New tricyclic amines | |
DE69818678D1 (de) | (+)-norcisapride verwendbar bei 5-ht3 und 5-ht4 bedingten krankheiten | |
EP0779889A4 (fr) | COMPOSES DE PYRAZOLO 3,4-g]QUINOXALINE INHIBANT LA TYROSINE-KINASE DES PROTEINES DU RECEPTEUR DE FCDP | |
FI103116B1 (fi) | Menetelmä uusien, terapeuttisesti käyttökelpoisten, N-substituoitujen atsaheterosyklisten karboksyylihappojohdannaisten valmistamiseksi | |
MY104521A (en) | Treatment of depression. | |
ES8703415A1 (es) | Procedimiento para preparar diselenobis-(amidas de acidos benzoicos). | |
HUT50343A (en) | Process for producing new condensed diazepinones and pharmaceutical compositions comprising same | |
ATE131055T1 (de) | Behandlung von kognitiven störungen. | |
TNSN92088A1 (fr) | Un nouveau compose therapeutique actif | |
IL101560A0 (en) | Condensed diazepinones,their preparation and pharmaceutical compositions containing them | |
MX9704704A (es) | Amidas de acido 4-amino-2-ureido-pirimidin-5-carboxilico, procedimientos para su obtencion, medicamentos que contienen estos compuestos, y su utilizacion. | |
ZA891769B (en) | Heterocyclic compounds | |
ES8702910A1 (es) | Procedimiento para la obtencion de benzodiazepinas. | |
RU95120819A (ru) | Наружное средство и способ лечения неврологических заболеваний и заболеваний опорно-двигательного аппарата с болевым синдромом и отечностью | |
ES2123796T3 (es) | Derivados de acidos fosfono-succinicos y su utilizacion como medicamentos. | |
RU95101233A (ru) | Способ лечения нейросенсорной тугоухости |