TNSN92088A1 - Un nouveau compose therapeutique actif - Google Patents

Un nouveau compose therapeutique actif

Info

Publication number
TNSN92088A1
TNSN92088A1 TNTNSN92088A TNSN92088A TNSN92088A1 TN SN92088 A1 TNSN92088 A1 TN SN92088A1 TN TNSN92088 A TNTNSN92088 A TN TNSN92088A TN SN92088 A TNSN92088 A TN SN92088A TN SN92088 A1 TNSN92088 A1 TN SN92088A1
Authority
TN
Tunisia
Prior art keywords
therapeutic compound
new active
active therapeutic
isopropyle
carbamylchromane
Prior art date
Application number
TNTNSN92088A
Other languages
English (en)
Inventor
Hammaarberg
Maria Eva
Johansson
George Lars
Ross
Bertil Svante
Thorberg
Olov Seth
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE9102905A external-priority patent/SE9102905D0/xx
Priority claimed from SE9202000A external-priority patent/SE9202000D0/xx
Application filed by Astra Ab filed Critical Astra Ab
Publication of TNSN92088A1 publication Critical patent/TNSN92088A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

3-(N-ISOPROPYLE-N-n-PROPYLAMINE)-5-(N-ISOPROPYLE) CARBAMYLCHROMANE COMME RACEMATE ET (R) ENANTIOMERE ET LEURS SELS, PROCEDE DE LEUR PREPARATION, COMPOSITION PHARMACEUTIQUE, UTILISATION ET METHODE DE TRAITEMENT DES TROUBLES DU SYSTEME NERNEUX CENTRAL
TNTNSN92088A 1991-10-08 1992-10-08 Un nouveau compose therapeutique actif TNSN92088A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9102905A SE9102905D0 (sv) 1991-10-08 1991-10-08 A new therapeutically active compound and a process for its preparation
SE9202000A SE9202000D0 (sv) 1992-06-29 1992-06-29 A new therapeutically active compound

Publications (1)

Publication Number Publication Date
TNSN92088A1 true TNSN92088A1 (fr) 1993-06-08

Family

ID=26661197

Family Applications (1)

Application Number Title Priority Date Filing Date
TNTNSN92088A TNSN92088A1 (fr) 1991-10-08 1992-10-08 Un nouveau compose therapeutique actif

Country Status (32)

Country Link
EP (3) EP0703229A3 (fr)
JP (1) JPH07500320A (fr)
CN (2) CN1072411A (fr)
AP (1) AP338A (fr)
AT (1) ATE139774T1 (fr)
AU (1) AU667687B2 (fr)
BG (1) BG98684A (fr)
CA (1) CA2118708A1 (fr)
CY (1) CY1992A (fr)
CZ (1) CZ51094A3 (fr)
DE (1) DE69211857T2 (fr)
DK (1) DK0607274T3 (fr)
EE (1) EE02981B1 (fr)
ES (1) ES2089571T3 (fr)
FI (1) FI941616A0 (fr)
GR (1) GR3020608T3 (fr)
HK (1) HK55997A (fr)
HR (1) HRP920935A2 (fr)
HU (1) HUT68834A (fr)
IL (1) IL103373A0 (fr)
IS (2) IS1644B (fr)
MA (1) MA22674A1 (fr)
MX (1) MX9205744A (fr)
MY (1) MY131174A (fr)
NO (1) NO941256L (fr)
NZ (2) NZ270595A (fr)
PL (1) PL171013B1 (fr)
SI (1) SI9200249A (fr)
SK (1) SK36194A3 (fr)
TN (1) TNSN92088A1 (fr)
WO (1) WO1993007135A1 (fr)
YU (1) YU90492A (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5420151A (en) * 1989-12-22 1995-05-30 Aktiebolaget Astra Chroman derivatives
US5990114A (en) * 1996-02-28 1999-11-23 Recordati, S.A., Chemical And Pharmaceutical Company Use of 5-HT1A receptor antagonists for the treatment of urinary incontinence
US7189753B1 (en) 1997-11-06 2007-03-13 Cady Roger K Preemptive prophylaxis of migraine
CA2345079C (fr) * 1998-09-23 2011-06-21 Research Development Foundation Tocopherols, tocotrienols, autres derives de chromane et de chaines laterales et leurs utilisations
US6235938B1 (en) * 1999-06-10 2001-05-22 Yale University Transition metal-catalyzed process for preparing N-aryl amine compounds
JP2019523279A (ja) 2016-07-29 2019-08-22 サノビオン ファーマシューティカルズ インクＳｕｎｏｖｉｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃ． 化合物および組成物ならびにそれらの使用
CA3070993A1 (fr) 2017-08-02 2019-02-07 Sunovion Pharmaceuticals Inc. Composes d'isochromane et leurs utilisations

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0222996B1 (fr) * 1985-09-03 1991-05-22 Ciba-Geigy Ag 3-Amino-dihydro(1)benzopyranne et benzothiopyranne
US4801605A (en) * 1986-08-29 1989-01-31 Ciba-Geigy Corporation 3-amino-dihydro-[1]-benzopyrans and benzothiopyrans
SE8605504D0 (sv) * 1986-12-19 1986-12-19 Astra Laekemedel Ab Novel chroman derivatives
JPH021429A (ja) * 1988-06-09 1990-01-05 Toray Ind Inc 光学活性１−メチル−３−フェニルプロピルアミンの製造方法
SE8904361D0 (sv) * 1989-12-22 1989-12-22 Astra Ab New chroman and thiochroman derivatives

Also Published As

Publication number Publication date
CN1072411A (zh) 1993-05-26
ES2089571T3 (es) 1996-10-01
JPH07500320A (ja) 1995-01-12
WO1993007135A1 (fr) 1993-04-15
CZ51094A3 (en) 1994-11-16
EP0703229A2 (fr) 1996-03-27
DE69211857T2 (de) 1996-10-24
HRP920935A2 (en) 1995-08-31
MY131174A (en) 2007-07-31
EP0607274A1 (fr) 1994-07-27
ATE139774T1 (de) 1996-07-15
SK36194A3 (en) 1994-12-07
NO941256D0 (no) 1994-04-07
IL103373A0 (en) 1993-03-15
NZ244618A (en) 1996-10-28
DE69211857D1 (de) 1996-08-01
AU2768492A (en) 1993-05-03
GR3020608T3 (en) 1996-10-31
NZ270595A (en) 1996-10-28
AP338A (en) 1994-04-26
CY1992A (en) 1997-09-05
SI9200249A (en) 1993-06-30
EP0538222A1 (fr) 1993-04-21
HK55997A (en) 1997-05-09
PL171013B1 (pl) 1997-02-28
FI941616A (fi) 1994-04-08
IS1644B (is) 1997-03-25
IS3929A (is) 1993-04-09
IS4310A (is) 1993-04-09
CA2118708A1 (fr) 1993-04-15
EE02981B1 (et) 1997-04-15
AP9200434A0 (en) 1992-10-31
AU667687B2 (en) 1996-04-04
HUT68834A (en) 1995-08-28
DK0607274T3 (da) 1996-11-04
NO941256L (no) 1994-04-07
HU9400993D0 (en) 1994-08-29
MA22674A1 (fr) 1993-07-01
BG98684A (en) 1995-05-31
EP0703229A3 (fr) 1996-06-26
EP0607274B1 (fr) 1996-06-26
CN1146992A (zh) 1997-04-09
YU90492A (sh) 1995-12-04
FI941616A0 (fi) 1994-04-08
MX9205744A (es) 1993-04-01

Similar Documents

Publication Publication Date Title
FI973163A0 (fi) Pidätyskyvyttömyyden hoitaminen käyttämällä (S)-oksibutyniiniä ja (S)-desetyylioksibutyniiniä
DE69326637D1 (de) 1,4-Disubstituierte Piperazine zur Behandlung von Erkrankungen des Zentralnervensystems und von nervenendokrinen Erkrankungen
HUP9600448A2 (hu) Naftilvegyületek, e vegyületeket tartalmazó gyógyszerkészítmények, eljárás előállításukra, intermedierjeik és alkalmazásuk
UA41906C2 (uk) Спосіб лікування неврологічних порушень, викликаних травмами
ZA953469B (en) New compound
TNSN88096A1 (fr) Nouveau n-(1-alkyl-3-hydroxy-4-piperidyl)
FR2670491B1 (fr) Nouvelles piperazines 1,4-disubstituees, leur procede de preparation et les compositions pharmaceutiques les renfermant.
ES2191069T3 (es) Diaril-2-(5h)-furanonas como inhibidores de cox-2.
BE1002415A4 (fr) 1-(4-aminophenyl)-4-methyl-7,8-methylenedioxy-3,4-dihydro-5h-2,3-benzodiazepine, ses sels d'addition acides et procede pour les preparer.
TNSN92088A1 (fr) Un nouveau compose therapeutique actif
DK406987A (da) Nye bisfosfonsyrederivater, deres fremstilling og brug
ES8305351A1 (es) Procedimiento para la preparacion de derivados de isoquino- leina
MA26732A1 (fr) Composition pharmaceutique nouvelle comprenant un inhibiteur de nos, et procede pour sa preparation
TNSN90021A1 (fr) Procede de preparation de tetrahydroimidazo (1,4) benzodiazepin -2- thiones antivirales
PT100415A (pt) Novas morfolinas de accao farmaceutica, e processo para a sua preparacao
MY104521A (en) Treatment of depression.
TNSN92017A1 (fr) Procede de preparation, d'un derive de benzothiazole, et d'une composition pharmaceutique le contenant et procede de traitement en comportant application
ES8304976A1 (es) "procedimiento para la preparacion de derivados triptaminicos sustituidos de tieniloxipropanolaminas, racemicos y opticamente activos".
RU99128026A (ru) Новая соль
US4459310A (en) Method for cholesterol lowering
MX9707596A (es) Benzamidas, el uso de las mismas, composiciones que las contienen, para el tratamiento del transtorno neurodegenerativo, y procedimiento para la preparacion del mismo.
ATE131055T1 (de) Behandlung von kognitiven störungen.
DE3362260D1 (en) (-)-15-deoxyspergualin, a process for the preparation of the same, and a pharmaceutical composition containing the same
PT78071B (fr) Procede de preparation de nouvelles compositions pharmaceutiques renfermant des derives d'amides des acides mercaptoaceptique et 3-mercaptopropionique
HU9503099D0 (en) New piperazinyl-alkylthio-pyrimidine derivatives, pharmaceutical compositions containing them, and process for producing the active components