MX9704704A - Amidas de acido 4-amino-2-ureido-pirimidin-5-carboxilico, procedimientos para su obtencion, medicamentos que contienen estos compuestos, y su utilizacion. - Google Patents

Amidas de acido 4-amino-2-ureido-pirimidin-5-carboxilico, procedimientos para su obtencion, medicamentos que contienen estos compuestos, y su utilizacion.

Info

Publication number
MX9704704A
MX9704704A MX9704704A MX9704704A MX9704704A MX 9704704 A MX9704704 A MX 9704704A MX 9704704 A MX9704704 A MX 9704704A MX 9704704 A MX9704704 A MX 9704704A MX 9704704 A MX9704704 A MX 9704704A
Authority
MX
Mexico
Prior art keywords
ureide
pyrimidin
amino
compounds
preparation
Prior art date
Application number
MX9704704A
Other languages
English (en)
Inventor
Hans Georg Boger
Axel Hoffmann
Gerhard Jahne
Hans-Ludwig Schafer
Norbert Krass
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of MX9704704A publication Critical patent/MX9704704A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Amidas de ácido 4-amino-2-ureido-pirimidin-5-carboxílico, procedimientos para su obtencion, medicamentos que contienen estos compuestos, y su utilizacion. Se describen amidas de ácido 4-amino-2-ureido-pirimidin-5-carboxílico, de formula I (Ver Formula) en la cual R1 hasta R3 tienen los significados indicados, así como sus sales fisiologicamente tolerables y un procedimiento para su preparacion. Los compuestos son apropiados para el tratamiento de trastornos del metabolismo lipídico.
MX9704704A 1996-06-24 1997-06-23 Amidas de acido 4-amino-2-ureido-pirimidin-5-carboxilico, procedimientos para su obtencion, medicamentos que contienen estos compuestos, y su utilizacion. MX9704704A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19625089A DE19625089A1 (de) 1996-06-24 1996-06-24 4-Amino-2-ureido-pyrimidin-5-carbonsäureamide, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung

Publications (1)

Publication Number Publication Date
MX9704704A true MX9704704A (es) 1997-12-31

Family

ID=7797762

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9704704A MX9704704A (es) 1996-06-24 1997-06-23 Amidas de acido 4-amino-2-ureido-pirimidin-5-carboxilico, procedimientos para su obtencion, medicamentos que contienen estos compuestos, y su utilizacion.

Country Status (11)

Country Link
US (1) US5939424A (es)
EP (1) EP0816358B1 (es)
JP (1) JP4101906B2 (es)
AT (1) ATE281452T1 (es)
CA (1) CA2208630C (es)
DE (2) DE19625089A1 (es)
DK (1) DK0816358T3 (es)
ES (1) ES2230575T3 (es)
MX (1) MX9704704A (es)
NO (1) NO312414B1 (es)
PT (1) PT816358E (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19625088A1 (de) * 1996-06-24 1998-01-02 Hoechst Ag 4-Amino-2-ureido-pyrimidin-5-carbonsäureamide, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung
US6887712B1 (en) * 1998-11-09 2005-05-03 Atherogenics, Inc. Methods and compositions to lower plasma cholesterol levels
US7087597B1 (en) 1999-10-12 2006-08-08 Takeda Pharmaceutical Company Limited Pyrimidine 5-carboxamide compounds, process for producing the same and use thereof
US7176310B1 (en) 2002-04-09 2007-02-13 Ucb Sa Pyrimidinecarboxamide derivatives and their use as anti-inflammatory agents
CA2553968A1 (en) * 2004-01-23 2005-08-11 Amgen Inc. Vanilloid receptor ligands and their use in treatments of inflammatory and neuropathic pain
JP2011057661A (ja) * 2009-08-14 2011-03-24 Bayer Cropscience Ag 殺虫性カルボキサミド類

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2853220A1 (de) * 1978-12-09 1980-07-03 Hoechst Ag Neue amino-pyrimidin-carbanilide, verfahren zu ihrer herstellung, diese verbindungen enthaltende arzneimittel und ihre verwendung
DE3522940A1 (de) * 1985-06-27 1987-01-08 Hoechst Ag 4-amino-2-(imidazolidin-2-on-1-yl)-pyrimidin-5-carbonsaeure-(n-(3-trifluormethyl-phenyl)-amide) zur antithrombotischen prophylaxe und behandlung sowie ihre verwendung zur herstellung von antithrombotisch wirksamen arzneimitteln
EP0577877B1 (en) * 1991-09-04 1995-10-18 Sumitomo Electric Industries, Ltd. Adjusting shim
EP0557879B1 (de) * 1992-02-22 1997-01-08 Hoechst Aktiengesellschaft 4-Amino-2-ureido-pyrimidin-5-carbonsäureamide, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung
EP0557877B1 (de) * 1992-02-22 1997-09-24 Hoechst Aktiengesellschaft Lösliche Salze von 4-Amino-2-(4,4-dimethyl-imidazolidin-2-on-1-yl)-pyrimidin-5 -carbonsäure- N-methyl-N-(3-trifluormethyl-phenyl)- amid, Verfahren zu ihrer Herstellung, ihre Verwendung als Arzneimittel und Ausgangsprodukte
DE19625088A1 (de) * 1996-06-24 1998-01-02 Hoechst Ag 4-Amino-2-ureido-pyrimidin-5-carbonsäureamide, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung

Also Published As

Publication number Publication date
US5939424A (en) 1999-08-17
DE19625089A1 (de) 1998-01-02
JPH1072463A (ja) 1998-03-17
ATE281452T1 (de) 2004-11-15
PT816358E (pt) 2005-01-31
DE59712053D1 (de) 2004-12-09
CA2208630A1 (en) 1997-12-24
EP0816358B1 (de) 2004-11-03
JP4101906B2 (ja) 2008-06-18
DK0816358T3 (da) 2005-03-07
NO312414B1 (no) 2002-05-06
ES2230575T3 (es) 2005-05-01
NO972943L (no) 1997-12-29
EP0816358A1 (de) 1998-01-07
NO972943D0 (no) 1997-06-23
CA2208630C (en) 2006-07-11

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Legal Events

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