SV2016005214A - Sistema de administración farmacológico - Google Patents

Sistema de administración farmacológico

Info

Publication number
SV2016005214A
SV2016005214A SV2016005214A SV2016005214A SV2016005214A SV 2016005214 A SV2016005214 A SV 2016005214A SV 2016005214 A SV2016005214 A SV 2016005214A SV 2016005214 A SV2016005214 A SV 2016005214A SV 2016005214 A SV2016005214 A SV 2016005214A
Authority
SV
El Salvador
Prior art keywords
thermoplastic polymer
administration system
therapeutic
agent
pharmacological administration
Prior art date
Application number
SV2016005214A
Other languages
English (en)
Inventor
Willy J H Verhoeven
Graaff Wouter De
Original Assignee
Merck Sharp & Dohme
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Sharp & Dohme filed Critical Merck Sharp & Dohme
Publication of SV2016005214A publication Critical patent/SV2016005214A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816—Wall or shell material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

EN EL PRESENTE DOCUMENTO SE DESCRIBE UN SISTEMA DE ADMINISTRACIÓN FARMACOLÓGICO INTRAVAGINAL QUE COMPRENDE (I) UN NÚCLEO QUE COMPRENDE UN PRIMER POLÍMERO TERMOPLÁSTICO Y UN PRIMER AGENTE TERAPÉUTICO, EN EL QUE EL PRIMER AGENTE TERAPÉUTICO SE DISUELVE EN EL PRIMER POLÍMERO TERMOPLÁSTICO, Y (II) UNA CAPA EXTERNA QUE RODEA EL NÚCLEO QUE COMPRENDE UN SEGUNDO POLÍMERO TERMOPLÁSTICO, EN EL QUE EL PRIMER AGENTE TERAPÉUTICO ES MENOS PERMEABLE EN EL SEGUNDO POLÍMERO TERMOPLÁSTICO QUE EL PRIMER POLÍMERO TERMOPLÁSTICO, Y UN SEGUNDO AGENTE TERAPÉUTICO EN FORMA SÓLIDA, EN EL QUE EL SEGUNDO AGENTE TERAPÉUTICO ESTÁ CARGADO EN UNA PORCIÓN DE LA CAPA EXTERNA
SV2016005214A 2013-12-11 2016-06-10 Sistema de administración farmacológico SV2016005214A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361914500P 2013-12-11 2013-12-11
EP13196737 2013-12-11

Publications (1)

Publication Number Publication Date
SV2016005214A true SV2016005214A (es) 2016-11-21

Family

ID=49759119

Family Applications (1)

Application Number Title Priority Date Filing Date
SV2016005214A SV2016005214A (es) 2013-12-11 2016-06-10 Sistema de administración farmacológico

Country Status (23)

Country Link
US (1) US10413504B2 (es)
EP (1) EP3079660B1 (es)
JP (1) JP6251396B2 (es)
KR (1) KR101808977B1 (es)
CN (1) CN105979930B (es)
AP (1) AP2016009223A0 (es)
AU (1) AU2014363724B2 (es)
BR (1) BR112016013325B1 (es)
CA (1) CA2931559C (es)
CR (1) CR20160261A (es)
DO (1) DOP2016000132A (es)
EA (1) EA031802B1 (es)
HK (1) HK1224208A1 (es)
IL (1) IL245544A0 (es)
MA (1) MA39059A1 (es)
MD (1) MD20160079A2 (es)
MX (1) MX2016007681A (es)
PE (1) PE20160680A1 (es)
PH (1) PH12016501083A1 (es)
SG (1) SG11201604660VA (es)
SV (1) SV2016005214A (es)
TW (1) TW201607563A (es)
WO (1) WO2015086491A1 (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10596103B2 (en) 2013-12-11 2020-03-24 Merek Sharp & Dohme B.V. Drug delivery system for delivery of anti-virals
US10413504B2 (en) 2013-12-11 2019-09-17 Merck Sharp & Dohme Corp. Intravaginal ring drug delivery system
CN105828787B (zh) 2013-12-19 2019-07-26 宝洁公司 使用氧代乙酸和/或它们的衍生物使角蛋白纤维成形
MX2016008163A (es) 2013-12-19 2016-09-16 Procter & Gamble Formacion de fibras de queratina mediante el uso de una composicion reductora y una composicion fijadora.
MX363629B (es) 2013-12-19 2019-03-28 Procter & Gamble Formar fibras de queratina con el uso de un agente activo que comprende un grupo funcional seleccionado del grupo que consiste en: -c(=o)-, -c(=o)-h y -c(=o)-o-.
US11110046B2 (en) 2013-12-19 2021-09-07 The Procter And Gamble Company Shaping keratin fibres using 2-hydroxypropane-1,2,3-tricarboxylic acid and/or 1,2,3,4-butanetetracarboxylic acid
MX361102B (es) 2013-12-19 2018-11-27 Procter & Gamble Modelado de fibras de queratina con el uso de un agente activo que comprende al menos dos grupos funcionales seleccionados de: -c(oh)- y -c(=o)oh.
MX2016007998A (es) 2013-12-19 2016-09-13 Procter & Gamble Modelado de fibras de queratina mediante el uso de ester de carbonato.
WO2015094757A1 (en) 2013-12-19 2015-06-25 The Procter & Gamble Company Shaping keratin fibres using a sugar
EP3017809A1 (en) * 2014-11-07 2016-05-11 Ferring B.V. Drug-device unit containing quinagolide
CN107106472A (zh) 2014-12-19 2017-08-29 宝洁公司 利用阿拉伯糖和碳酸亚乙酯使角蛋白纤维成形
CN107106438A (zh) 2014-12-19 2017-08-29 宝洁公司 成形角蛋白纤维的方法
WO2016205580A1 (en) 2015-06-18 2016-12-22 The Procter & Gamble Company Shaping keratin fibres using dialdehyde compounds
EP3334413B1 (en) * 2015-08-11 2022-05-18 PTT Holding Aps A delivery device
EP3395335A1 (en) * 2017-04-24 2018-10-31 Kern Pharma, S.L. Vaginal ring for the simultaneous release of two active ingredients
DE102017113166A1 (de) * 2017-06-14 2018-12-20 Amw Gmbh Depotform zur Abgabe eines Östrogen-Wirkstoffs
US11690807B2 (en) 2018-05-24 2023-07-04 Celanese Eva Performance Polymers Llc Implantable device for sustained release of a macromolecular drug compound
SG11202005949UA (en) 2018-05-24 2020-07-29 Celanese Eva Performance Polymers Corp Implantable device for sustained release of a macromolecular drug compound
US10918649B2 (en) 2019-06-21 2021-02-16 The Population Council, Inc. System for providing birth control
WO2023141198A1 (en) * 2022-01-21 2023-07-27 The Population Council, Inc. Combination therapy intravaginal rings

Family Cites Families (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3545439A (en) 1968-01-04 1970-12-08 Upjohn Co Medicated devices and methods
US3854480A (en) 1969-04-01 1974-12-17 Alza Corp Drug-delivery system
US3995634A (en) 1975-12-02 1976-12-07 The Procter & Gamble Company Vaginal cavity dispensing means and method
US3995633A (en) 1975-12-02 1976-12-07 The Procter & Gamble Company Vaginal Medicament dispensing device
US4237885A (en) 1978-10-23 1980-12-09 Alza Corporation Delivery system with mated members for storing and releasing a plurality of beneficial agents
US4292965A (en) 1978-12-29 1981-10-06 The Population Council, Inc. Intravaginal ring
DE3040978A1 (de) 1980-10-28 1982-05-27 Schering Ag, 1000 Berlin Und 4619 Bergkamen Vaginalring
US4629449A (en) 1982-07-29 1986-12-16 Alza Corporation Vaginal dispenser for dispensing beneficial hormone
EP0162492B1 (en) 1984-04-11 1989-08-02 Thiemann Arzneimittel GmbH Dosage units for controlled release of active material
US4596576A (en) 1984-10-12 1986-06-24 Akzo N.V. Release system for two or more active substances
US4816258A (en) 1987-02-26 1989-03-28 Alza Corporation Transdermal contraceptive formulations
DE19975054I2 (de) 1987-08-08 2000-04-13 Akzo Nobel Nv Kontrazeptives Implantat
AU3432689A (en) 1988-03-24 1989-10-16 Bukh Meditec A/S Controlled release composition
US5766632A (en) 1993-10-01 1998-06-16 Legere Pharmaceuticals, Ltd. Method of using lectins for contraception
JP3720386B2 (ja) 1993-12-27 2005-11-24 住友製薬株式会社 薬物放出制御製剤
DE69616551T2 (de) 1995-07-04 2002-05-29 Akzo Nobel Nv Ringförmige vorrichtung
US5972372A (en) 1996-07-31 1999-10-26 The Population Council, Inc. Intravaginal rings with insertable drug-containing core
FR2754179B1 (fr) 1996-10-08 1998-12-24 Theramex Nouvelle composition hormononale et son utilisation
IL123813A0 (en) * 1997-04-11 1998-10-30 Akzo Nobel Nv Drug delivery system for two or more active substances
CZ298362B6 (cs) 1997-12-12 2007-09-05 N.V. Organon Aseptický obal
BR9813740A (pt) 1997-12-18 2000-10-10 Lilly Co Eli Teriparatìdeo cristalino
US6579533B1 (en) 1999-11-30 2003-06-17 Bioasborbable Concepts, Ltd. Bioabsorbable drug delivery system for local treatment and prevention of infections
CN1536986B (zh) 2001-03-27 2012-07-04 沃纳奇尔科特(爱尔兰)有限公司 用于抗微生物剂给药的阴道内药物递送装置
JP2004535431A (ja) 2001-06-22 2004-11-25 サザン バイオシステムズ， インコーポレイテッド ゼロ次長期放出同軸インプラント
JP2005503389A (ja) 2001-08-31 2005-02-03 シエーリング オサケユイチア 薬物送達システム
MXPA04002980A (es) 2001-09-28 2005-06-20 Johnson & Johnson Formas de dosificacion que tienen un nucleo interior y coraza exterior con diferentes formas.
CN1242819C (zh) 2002-06-07 2006-02-22 上海市计划生育科学研究所 一种新型阴道环及制备方法
US6992219B2 (en) 2002-08-09 2006-01-31 Cephalon France Modafinil polymorphic forms
TWI336627B (en) * 2003-05-23 2011-02-01 Organon Nv Drug delivery system,and use and manufacturing method thereof
US20070043332A1 (en) 2003-07-10 2007-02-22 Galen (Chemiclas) Liimited Intravaginal drug delivery devices
EP2295041A3 (en) * 2003-09-29 2012-01-04 Novo Nordisk Femcare AG HRT formulations
MXPA06010905A (es) * 2004-03-24 2007-03-08 Organon Nv Sistema para el suministro de farmacos basados en copolimeros de polietileno y acetato de vinilo.
KR20060046263A (ko) * 2004-08-04 2006-05-17 도쿄파츠고교 가부시키가이샤 편평형 진동모터를 내장시킨 전자음향변환기
TW200727920A (en) 2005-06-21 2007-08-01 Organon Nv New regimens for oral monophasic contraceptives
CA2669066A1 (en) * 2006-11-20 2008-05-29 N.V. Organon Helically-shaped drug delivery system
EP3391874A3 (en) 2007-02-12 2019-04-24 Particle Sciences, Inc. Delivery devices containing encapsulated and/or particle- bound active pharmaceutical ingredients
AR065816A1 (es) 2007-03-26 2009-07-01 Theramex Regimen anticonceptivo oral
KR101996336B1 (ko) 2007-09-07 2019-07-04 마티 테라퓨틱스 인코포레이티드 치료 약제의 서방성 약물 코어
AR066166A1 (es) 2007-09-21 2009-07-29 Organon Nv Sistema de suministro de droga
TW200927141A (en) * 2007-11-22 2009-07-01 Bayer Schering Pharma Oy Vaginal delivery system
MX2012000948A (es) * 2009-07-21 2012-02-28 Population Council Inc Anillo vaginal gradiente multicapas.
EP2468750A1 (en) 2010-12-13 2012-06-27 Chemo Ibérica, S.A. Polymorphic forms of asenapine maleate and processes for their preparation
TW201332585A (zh) 2012-02-14 2013-08-16 Chemo Res S L 核鞘藥物遞送裝置
US10413504B2 (en) 2013-12-11 2019-09-17 Merck Sharp & Dohme Corp. Intravaginal ring drug delivery system

Also Published As

Publication number Publication date
PH12016501083A1 (en) 2016-07-25
JP6251396B2 (ja) 2017-12-20
AU2014363724B2 (en) 2017-02-23
EP3079660B1 (en) 2021-03-03
WO2015086491A1 (en) 2015-06-18
CN105979930B (zh) 2019-11-19
EA201691193A1 (ru) 2016-09-30
US10413504B2 (en) 2019-09-17
PE20160680A1 (es) 2016-07-31
HK1224208A1 (zh) 2017-08-18
KR101808977B1 (ko) 2017-12-13
MD20160079A2 (ro) 2016-10-31
SG11201604660VA (en) 2016-07-28
TW201607563A (zh) 2016-03-01
CA2931559C (en) 2018-03-13
CA2931559A1 (en) 2015-06-18
DOP2016000132A (es) 2016-07-31
IL245544A0 (en) 2016-06-30
BR112016013325B1 (pt) 2022-11-29
AU2014363724A1 (en) 2016-05-26
BR112016013325A2 (es) 2017-08-08
US20150157561A1 (en) 2015-06-11
EP3079660A1 (en) 2016-10-19
CR20160261A (es) 2016-08-16
EA031802B1 (ru) 2019-02-28
KR20160095110A (ko) 2016-08-10
MX2016007681A (es) 2016-10-14
JP2016539991A (ja) 2016-12-22
CN105979930A (zh) 2016-09-28
MA39059A1 (fr) 2018-08-31
AP2016009223A0 (en) 2016-05-31

Similar Documents

Publication Publication Date Title
SV2016005214A (es) Sistema de administración farmacológico
CR20140487A (es) Peliculas de capas multiples capaces de liberar ingredientes activos por un periodo limitado de tiempo
BR112016012615A8 (pt) sistemas, e kit
PE20150093A1 (es) Tuberia multicapa de material polimero, dispositivo para la fabricacion de tuberias multicapa y metodo para fabricar tuberias multicapa
CL2015002926A1 (es) Método de fabricación de la espuma absorbente de material compuesto.
AR081113A1 (es) Liberacion pulsatil de medicamentos desde un tapon de punctum
SE1650380A1 (sv) Oxygen barrier film and laminate and methods of manufacturing the same
CL2015001882A1 (es) Sistema de entrega de fragancias
CL2015002733A1 (es) Composición farmacéutica de clorhidrato de s-cetamina.
AR093411A1 (es) Metodos para formar y colocar pilares de soporte en una formacion subterranea
BR112013024585A8 (pt) formas de dosagem farmacêutica de liberação controlada
BR112016028643A2 (pt) ?dispositivo de vedação e sistema de entrega?
CR20160192A (es) Formulación de farmaco de liberación retardada
ES2527276T3 (es) Balón con superficie recubierta
DK2964088T3 (da) Vaginalt lægemiddeladministrations- og/eller diagnosesystem
CR20150414A (es) Tubo extrudible multicapa
DOP2016000024A (es) Comprimido farmacéutico que comprende ácido acetilsalicílico y clopidogrel
DOP2010000253A (es) Sistema de administracion de drogas con efecto estabilizante
EP2979857A4 (en) LAMINATED BODY, BARRIER FILM, AND METHOD OF MANUFACTURING THE SAME
CL2015003779A1 (es) Dispositivo de oclusión con via abierta.
MX2020003667A (es) Sistema terapeutico transdermico para la administracion transdermica de guanfacina que comprende un polimero de silicona.
CU20150142A7 (es) Método y sistema para la fabricación de artículos alargados de concreto
AR098129A1 (es) Preparación y administración de soluciones de liberación sostenida de óxido nítrico
BR112017011433A2 (pt) roda abrasiva não tecida com uma camada de barreira à umidade
UY34178A (es) Dosificación y administración de anticuerpos anti-erbb3 en combinación con paclitaxel para el tratamiento de cánceres ginecológicos.