MX2016007681A - Sistema de administracion farmacologico. - Google Patents
Sistema de administracion farmacologico.Info
- Publication number
- MX2016007681A MX2016007681A MX2016007681A MX2016007681A MX2016007681A MX 2016007681 A MX2016007681 A MX 2016007681A MX 2016007681 A MX2016007681 A MX 2016007681A MX 2016007681 A MX2016007681 A MX 2016007681A MX 2016007681 A MX2016007681 A MX 2016007681A
- Authority
- MX
- Mexico
- Prior art keywords
- therapeutic agent
- thermoplastic polymer
- delivery system
- drug delivery
- core
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
- A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
- A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Urology & Nephrology (AREA)
- Inorganic Chemistry (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
En el presente documento se describe un sistema de administración farmacológico intravaginal que comprende (i) un núcleo que comprende un primer polímero termoplástico y un primer agente terapéutico, en el que el primer agente terapéutico se disuelve en el primer polímero termoplástico, y (ii) una capa externa que rodea el núcleo que comprende un segundo polímero termoplástico, en el que el primer agente terapéutico es menos permeable en el segundo polímero termoplástico que el primer polímero termoplástico, y un segundo agente terapéutico en forma sólida, en el que el segundo agente terapéutico está cargado en una porción de la capa externa.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361914500P | 2013-12-11 | 2013-12-11 | |
EP13196737 | 2013-12-11 | ||
PCT/EP2014/076823 WO2015086491A1 (en) | 2013-12-11 | 2014-12-08 | Drug delivery system. |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2016007681A true MX2016007681A (es) | 2016-10-14 |
Family
ID=49759119
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2016007681A MX2016007681A (es) | 2013-12-11 | 2014-12-08 | Sistema de administracion farmacologico. |
Country Status (23)
Country | Link |
---|---|
US (1) | US10413504B2 (es) |
EP (1) | EP3079660B1 (es) |
JP (1) | JP6251396B2 (es) |
KR (1) | KR101808977B1 (es) |
CN (1) | CN105979930B (es) |
AP (1) | AP2016009223A0 (es) |
AU (1) | AU2014363724B2 (es) |
BR (1) | BR112016013325B1 (es) |
CA (1) | CA2931559C (es) |
CR (1) | CR20160261A (es) |
DO (1) | DOP2016000132A (es) |
EA (1) | EA031802B1 (es) |
HK (1) | HK1224208A1 (es) |
IL (1) | IL245544A0 (es) |
MA (1) | MA39059A1 (es) |
MD (1) | MD20160079A2 (es) |
MX (1) | MX2016007681A (es) |
PE (1) | PE20160680A1 (es) |
PH (1) | PH12016501083A1 (es) |
SG (1) | SG11201604660VA (es) |
SV (1) | SV2016005214A (es) |
TW (1) | TW201607563A (es) |
WO (1) | WO2015086491A1 (es) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10596103B2 (en) | 2013-12-11 | 2020-03-24 | Merek Sharp & Dohme B.V. | Drug delivery system for delivery of anti-virals |
US10413504B2 (en) | 2013-12-11 | 2019-09-17 | Merck Sharp & Dohme Corp. | Intravaginal ring drug delivery system |
WO2015094757A1 (en) | 2013-12-19 | 2015-06-25 | The Procter & Gamble Company | Shaping keratin fibres using a sugar |
JP6314235B2 (ja) | 2013-12-19 | 2018-04-18 | ザ プロクター アンド ギャンブル カンパニー | オキソエタン酸及び/又はその誘導体を使用したヒトの毛髪をまっすぐにする方法 |
MX361102B (es) | 2013-12-19 | 2018-11-27 | Procter & Gamble | Modelado de fibras de queratina con el uso de un agente activo que comprende al menos dos grupos funcionales seleccionados de: -c(oh)- y -c(=o)oh. |
CA2932628A1 (en) | 2013-12-19 | 2015-06-25 | The Procter & Gamble Company | Shaping keratin fibres using a reducing composition and a fixing composition |
EP3082744A1 (en) | 2013-12-19 | 2016-10-26 | The Procter & Gamble Company | Shaping keratin fibres using carbonate ester |
US11110046B2 (en) | 2013-12-19 | 2021-09-07 | The Procter And Gamble Company | Shaping keratin fibres using 2-hydroxypropane-1,2,3-tricarboxylic acid and/or 1,2,3,4-butanetetracarboxylic acid |
EP3082733A1 (en) | 2013-12-19 | 2016-10-26 | The Procter & Gamble Company | Shaping keratin fibres using an active agent comprising a functional group selected from the group consisting of: -c(=o)-, -c(=o)-h, and -c(=o)-o- |
EP3017809A1 (en) * | 2014-11-07 | 2016-05-11 | Ferring B.V. | Drug-device unit containing quinagolide |
EP3297730A1 (en) | 2014-12-19 | 2018-03-28 | The Procter and Gamble Company | Method of shaping keratin fibres |
MX2017008204A (es) | 2014-12-19 | 2017-10-06 | Procter & Gamble | Conformacion de las fibras de queratina mediante el uso de arabinosa y carbonato de etileno. |
US10945931B2 (en) | 2015-06-18 | 2021-03-16 | The Procter And Gamble Company | Shaping keratin fibres using dialdehyde compounds |
CN117462477A (zh) * | 2015-08-11 | 2024-01-30 | Ptt控股公司 | 递送装置 |
EP3395335A1 (en) * | 2017-04-24 | 2018-10-31 | Kern Pharma, S.L. | Vaginal ring for the simultaneous release of two active ingredients |
DE102017113166A1 (de) * | 2017-06-14 | 2018-12-20 | Amw Gmbh | Depotform zur Abgabe eines Östrogen-Wirkstoffs |
WO2019226516A1 (en) | 2018-05-24 | 2019-11-28 | Celanese EVA Performance Polymers Corporation | Implantable device for sustained release of a macromolecular drug compound |
JP2021524840A (ja) | 2018-05-24 | 2021-09-16 | セラニーズ・イーブイエイ・パフォーマンス・ポリマーズ・エルエルシー | 高分子薬剤化合物の持続放出用の埋め込み型デバイス |
US10918649B2 (en) | 2019-06-21 | 2021-02-16 | The Population Council, Inc. | System for providing birth control |
WO2023141198A1 (en) * | 2022-01-21 | 2023-07-27 | The Population Council, Inc. | Combination therapy intravaginal rings |
WO2024115763A1 (en) | 2022-12-02 | 2024-06-06 | Vari Bioscience Gmbh | Estriol vaginal ring |
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US3854480A (en) | 1969-04-01 | 1974-12-17 | Alza Corp | Drug-delivery system |
US3995633A (en) | 1975-12-02 | 1976-12-07 | The Procter & Gamble Company | Vaginal Medicament dispensing device |
US3995634A (en) | 1975-12-02 | 1976-12-07 | The Procter & Gamble Company | Vaginal cavity dispensing means and method |
US4237885A (en) | 1978-10-23 | 1980-12-09 | Alza Corporation | Delivery system with mated members for storing and releasing a plurality of beneficial agents |
US4292965A (en) | 1978-12-29 | 1981-10-06 | The Population Council, Inc. | Intravaginal ring |
DE3040978A1 (de) | 1980-10-28 | 1982-05-27 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Vaginalring |
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EP0162492B1 (en) | 1984-04-11 | 1989-08-02 | Thiemann Arzneimittel GmbH | Dosage units for controlled release of active material |
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TW200930343A (en) * | 2007-09-21 | 2009-07-16 | Organon Nv | Drug delivery system |
TW200927141A (en) * | 2007-11-22 | 2009-07-01 | Bayer Schering Pharma Oy | Vaginal delivery system |
CN102497855B (zh) | 2009-07-21 | 2013-12-25 | 人口委员会股份有限公司 | 多层梯度的阴道环 |
EP2468750A1 (en) | 2010-12-13 | 2012-06-27 | Chemo Ibérica, S.A. | Polymorphic forms of asenapine maleate and processes for their preparation |
TW201332585A (zh) | 2012-02-14 | 2013-08-16 | Chemo Res S L | 核鞘藥物遞送裝置 |
US10413504B2 (en) | 2013-12-11 | 2019-09-17 | Merck Sharp & Dohme Corp. | Intravaginal ring drug delivery system |
-
2014
- 2014-12-04 US US14/560,494 patent/US10413504B2/en active Active
- 2014-12-08 CA CA2931559A patent/CA2931559C/en active Active
- 2014-12-08 AP AP2016009223A patent/AP2016009223A0/en unknown
- 2014-12-08 EA EA201691193A patent/EA031802B1/ru not_active IP Right Cessation
- 2014-12-08 SG SG11201604660VA patent/SG11201604660VA/en unknown
- 2014-12-08 AU AU2014363724A patent/AU2014363724B2/en active Active
- 2014-12-08 TW TW103142659A patent/TW201607563A/zh unknown
- 2014-12-08 EP EP14809832.0A patent/EP3079660B1/en active Active
- 2014-12-08 PE PE2016000778A patent/PE20160680A1/es not_active Application Discontinuation
- 2014-12-08 WO PCT/EP2014/076823 patent/WO2015086491A1/en active Application Filing
- 2014-12-08 KR KR1020167018119A patent/KR101808977B1/ko active IP Right Grant
- 2014-12-08 MA MA39059A patent/MA39059A1/fr unknown
- 2014-12-08 CR CR20160261A patent/CR20160261A/es unknown
- 2014-12-08 BR BR112016013325-0A patent/BR112016013325B1/pt active IP Right Grant
- 2014-12-08 MD MDA20160079A patent/MD20160079A2/ro not_active Application Discontinuation
- 2014-12-08 CN CN201480067300.XA patent/CN105979930B/zh active Active
- 2014-12-08 MX MX2016007681A patent/MX2016007681A/es unknown
- 2014-12-08 JP JP2016538065A patent/JP6251396B2/ja active Active
-
2016
- 2016-05-08 IL IL245544A patent/IL245544A0/en unknown
- 2016-06-07 PH PH12016501083A patent/PH12016501083A1/en unknown
- 2016-06-10 DO DO2016000132A patent/DOP2016000132A/es unknown
- 2016-06-10 SV SV2016005214A patent/SV2016005214A/es unknown
- 2016-11-01 HK HK16112574.1A patent/HK1224208A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
SV2016005214A (es) | 2016-11-21 |
PE20160680A1 (es) | 2016-07-31 |
KR20160095110A (ko) | 2016-08-10 |
WO2015086491A1 (en) | 2015-06-18 |
KR101808977B1 (ko) | 2017-12-13 |
US10413504B2 (en) | 2019-09-17 |
AP2016009223A0 (en) | 2016-05-31 |
JP6251396B2 (ja) | 2017-12-20 |
EA201691193A1 (ru) | 2016-09-30 |
HK1224208A1 (zh) | 2017-08-18 |
EP3079660A1 (en) | 2016-10-19 |
TW201607563A (zh) | 2016-03-01 |
DOP2016000132A (es) | 2016-07-31 |
IL245544A0 (en) | 2016-06-30 |
AU2014363724A1 (en) | 2016-05-26 |
CR20160261A (es) | 2016-08-16 |
SG11201604660VA (en) | 2016-07-28 |
AU2014363724B2 (en) | 2017-02-23 |
BR112016013325B1 (pt) | 2022-11-29 |
CA2931559A1 (en) | 2015-06-18 |
CN105979930A (zh) | 2016-09-28 |
CA2931559C (en) | 2018-03-13 |
CN105979930B (zh) | 2019-11-19 |
BR112016013325A2 (es) | 2017-08-08 |
US20150157561A1 (en) | 2015-06-11 |
MA39059A1 (fr) | 2018-08-31 |
PH12016501083A1 (en) | 2016-07-25 |
EP3079660B1 (en) | 2021-03-03 |
EA031802B1 (ru) | 2019-02-28 |
MD20160079A2 (ro) | 2016-10-31 |
JP2016539991A (ja) | 2016-12-22 |
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