PE20160680A1 - Sistema de administracion farmacologica - Google Patents
Sistema de administracion farmacologicaInfo
- Publication number
- PE20160680A1 PE20160680A1 PE2016000778A PE2016000778A PE20160680A1 PE 20160680 A1 PE20160680 A1 PE 20160680A1 PE 2016000778 A PE2016000778 A PE 2016000778A PE 2016000778 A PE2016000778 A PE 2016000778A PE 20160680 A1 PE20160680 A1 PE 20160680A1
- Authority
- PE
- Peru
- Prior art keywords
- therapeutic agent
- thermoplastic polymer
- beta
- refers
- core
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
- A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
- A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Abstract
Se refiere a un sistema de administracion farmacologico intravaginal que comprende: (i) un nucleo que comprende un primer polimero termoplastico (por ejemplo un copolimero de etileno y acetato de vinilo) y un primer agente terapeutico (por ejemplo un progestageno como etonogestrel), en el que el primer agente terapeutico se disuelve en el primer polimero termoplastico, y (ii) una capa externa que rodea el nucleo que comprende un segundo polimero termoplastico, en el que el primer agente terapeutico es menos permeable en el segundo polimero termoplastico (por ejemplo un copolimero de etileno y acetato de vinilo) que el primer polimero termoplastico, y un segundo agente terapeutico (por ejemplo un estrogeno como 17-beta-estradiol o 17-beta-estradiol hemihidrato) en forma solida, en el que el segundo agente terapeutico esta cargado en una porcion de la capa externa. Tambien se refiere a un metodo de fabricacion del sistema; siendo util como metodo anticonceptivo o prevencion de enfermedades de transmision sexual
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361914500P | 2013-12-11 | 2013-12-11 | |
EP13196737 | 2013-12-11 |
Publications (1)
Publication Number | Publication Date |
---|---|
PE20160680A1 true PE20160680A1 (es) | 2016-07-31 |
Family
ID=49759119
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE2016000778A PE20160680A1 (es) | 2013-12-11 | 2014-12-08 | Sistema de administracion farmacologica |
Country Status (23)
Country | Link |
---|---|
US (1) | US10413504B2 (es) |
EP (1) | EP3079660B1 (es) |
JP (1) | JP6251396B2 (es) |
KR (1) | KR101808977B1 (es) |
CN (1) | CN105979930B (es) |
AP (1) | AP2016009223A0 (es) |
AU (1) | AU2014363724B2 (es) |
BR (1) | BR112016013325B1 (es) |
CA (1) | CA2931559C (es) |
CR (1) | CR20160261A (es) |
DO (1) | DOP2016000132A (es) |
EA (1) | EA031802B1 (es) |
HK (1) | HK1224208A1 (es) |
IL (1) | IL245544A0 (es) |
MA (1) | MA39059A1 (es) |
MD (1) | MD20160079A2 (es) |
MX (1) | MX2016007681A (es) |
PE (1) | PE20160680A1 (es) |
PH (1) | PH12016501083A1 (es) |
SG (1) | SG11201604660VA (es) |
SV (1) | SV2016005214A (es) |
TW (1) | TW201607563A (es) |
WO (1) | WO2015086491A1 (es) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10596103B2 (en) | 2013-12-11 | 2020-03-24 | Merek Sharp & Dohme B.V. | Drug delivery system for delivery of anti-virals |
US10413504B2 (en) | 2013-12-11 | 2019-09-17 | Merck Sharp & Dohme Corp. | Intravaginal ring drug delivery system |
CN105828787B (zh) | 2013-12-19 | 2019-07-26 | 宝洁公司 | 使用氧代乙酸和/或它们的衍生物使角蛋白纤维成形 |
MX2016008163A (es) | 2013-12-19 | 2016-09-16 | Procter & Gamble | Formacion de fibras de queratina mediante el uso de una composicion reductora y una composicion fijadora. |
MX363629B (es) | 2013-12-19 | 2019-03-28 | Procter & Gamble | Formar fibras de queratina con el uso de un agente activo que comprende un grupo funcional seleccionado del grupo que consiste en: -c(=o)-, -c(=o)-h y -c(=o)-o-. |
US11110046B2 (en) | 2013-12-19 | 2021-09-07 | The Procter And Gamble Company | Shaping keratin fibres using 2-hydroxypropane-1,2,3-tricarboxylic acid and/or 1,2,3,4-butanetetracarboxylic acid |
MX361102B (es) | 2013-12-19 | 2018-11-27 | Procter & Gamble | Modelado de fibras de queratina con el uso de un agente activo que comprende al menos dos grupos funcionales seleccionados de: -c(oh)- y -c(=o)oh. |
MX2016007998A (es) | 2013-12-19 | 2016-09-13 | Procter & Gamble | Modelado de fibras de queratina mediante el uso de ester de carbonato. |
WO2015094757A1 (en) | 2013-12-19 | 2015-06-25 | The Procter & Gamble Company | Shaping keratin fibres using a sugar |
EP3017809A1 (en) * | 2014-11-07 | 2016-05-11 | Ferring B.V. | Drug-device unit containing quinagolide |
CN107106472A (zh) | 2014-12-19 | 2017-08-29 | 宝洁公司 | 利用阿拉伯糖和碳酸亚乙酯使角蛋白纤维成形 |
CN107106438A (zh) | 2014-12-19 | 2017-08-29 | 宝洁公司 | 成形角蛋白纤维的方法 |
WO2016205580A1 (en) | 2015-06-18 | 2016-12-22 | The Procter & Gamble Company | Shaping keratin fibres using dialdehyde compounds |
EP3334413B1 (en) * | 2015-08-11 | 2022-05-18 | PTT Holding Aps | A delivery device |
EP3395335A1 (en) * | 2017-04-24 | 2018-10-31 | Kern Pharma, S.L. | Vaginal ring for the simultaneous release of two active ingredients |
DE102017113166A1 (de) * | 2017-06-14 | 2018-12-20 | Amw Gmbh | Depotform zur Abgabe eines Östrogen-Wirkstoffs |
US11690807B2 (en) | 2018-05-24 | 2023-07-04 | Celanese Eva Performance Polymers Llc | Implantable device for sustained release of a macromolecular drug compound |
SG11202005949UA (en) | 2018-05-24 | 2020-07-29 | Celanese Eva Performance Polymers Corp | Implantable device for sustained release of a macromolecular drug compound |
US10918649B2 (en) | 2019-06-21 | 2021-02-16 | The Population Council, Inc. | System for providing birth control |
WO2023141198A1 (en) * | 2022-01-21 | 2023-07-27 | The Population Council, Inc. | Combination therapy intravaginal rings |
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US3854480A (en) | 1969-04-01 | 1974-12-17 | Alza Corp | Drug-delivery system |
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DE3040978A1 (de) | 1980-10-28 | 1982-05-27 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Vaginalring |
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JP3720386B2 (ja) | 1993-12-27 | 2005-11-24 | 住友製薬株式会社 | 薬物放出制御製剤 |
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EP2468750A1 (en) | 2010-12-13 | 2012-06-27 | Chemo Ibérica, S.A. | Polymorphic forms of asenapine maleate and processes for their preparation |
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US10413504B2 (en) | 2013-12-11 | 2019-09-17 | Merck Sharp & Dohme Corp. | Intravaginal ring drug delivery system |
-
2014
- 2014-12-04 US US14/560,494 patent/US10413504B2/en active Active
- 2014-12-08 WO PCT/EP2014/076823 patent/WO2015086491A1/en active Application Filing
- 2014-12-08 JP JP2016538065A patent/JP6251396B2/ja active Active
- 2014-12-08 CA CA2931559A patent/CA2931559C/en active Active
- 2014-12-08 MX MX2016007681A patent/MX2016007681A/es unknown
- 2014-12-08 PE PE2016000778A patent/PE20160680A1/es not_active Application Discontinuation
- 2014-12-08 CN CN201480067300.XA patent/CN105979930B/zh active Active
- 2014-12-08 MD MDA20160079A patent/MD20160079A2/ro not_active Application Discontinuation
- 2014-12-08 EP EP14809832.0A patent/EP3079660B1/en active Active
- 2014-12-08 BR BR112016013325-0A patent/BR112016013325B1/pt active IP Right Grant
- 2014-12-08 EA EA201691193A patent/EA031802B1/ru not_active IP Right Cessation
- 2014-12-08 MA MA39059A patent/MA39059A1/fr unknown
- 2014-12-08 AU AU2014363724A patent/AU2014363724B2/en active Active
- 2014-12-08 CR CR20160261A patent/CR20160261A/es unknown
- 2014-12-08 KR KR1020167018119A patent/KR101808977B1/ko active IP Right Grant
- 2014-12-08 TW TW103142659A patent/TW201607563A/zh unknown
- 2014-12-08 SG SG11201604660VA patent/SG11201604660VA/en unknown
- 2014-12-08 AP AP2016009223A patent/AP2016009223A0/en unknown
-
2016
- 2016-05-08 IL IL245544A patent/IL245544A0/en unknown
- 2016-06-07 PH PH12016501083A patent/PH12016501083A1/en unknown
- 2016-06-10 SV SV2016005214A patent/SV2016005214A/es unknown
- 2016-06-10 DO DO2016000132A patent/DOP2016000132A/es unknown
- 2016-11-01 HK HK16112574.1A patent/HK1224208A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
PH12016501083A1 (en) | 2016-07-25 |
JP6251396B2 (ja) | 2017-12-20 |
AU2014363724B2 (en) | 2017-02-23 |
EP3079660B1 (en) | 2021-03-03 |
WO2015086491A1 (en) | 2015-06-18 |
CN105979930B (zh) | 2019-11-19 |
EA201691193A1 (ru) | 2016-09-30 |
US10413504B2 (en) | 2019-09-17 |
HK1224208A1 (zh) | 2017-08-18 |
KR101808977B1 (ko) | 2017-12-13 |
MD20160079A2 (ro) | 2016-10-31 |
SG11201604660VA (en) | 2016-07-28 |
TW201607563A (zh) | 2016-03-01 |
CA2931559C (en) | 2018-03-13 |
CA2931559A1 (en) | 2015-06-18 |
DOP2016000132A (es) | 2016-07-31 |
IL245544A0 (en) | 2016-06-30 |
BR112016013325B1 (pt) | 2022-11-29 |
AU2014363724A1 (en) | 2016-05-26 |
BR112016013325A2 (es) | 2017-08-08 |
US20150157561A1 (en) | 2015-06-11 |
EP3079660A1 (en) | 2016-10-19 |
SV2016005214A (es) | 2016-11-21 |
CR20160261A (es) | 2016-08-16 |
EA031802B1 (ru) | 2019-02-28 |
KR20160095110A (ko) | 2016-08-10 |
MX2016007681A (es) | 2016-10-14 |
JP2016539991A (ja) | 2016-12-22 |
CN105979930A (zh) | 2016-09-28 |
MA39059A1 (fr) | 2018-08-31 |
AP2016009223A0 (en) | 2016-05-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |