DOP2016000024A - Comprimido farmacéutico que comprende ácido acetilsalicílico y clopidogrel - Google Patents

Comprimido farmacéutico que comprende ácido acetilsalicílico y clopidogrel

Info

Publication number
DOP2016000024A
DOP2016000024A DO2016000024A DO2016000024A DOP2016000024A DO P2016000024 A DOP2016000024 A DO P2016000024A DO 2016000024 A DO2016000024 A DO 2016000024A DO 2016000024 A DO2016000024 A DO 2016000024A DO P2016000024 A DOP2016000024 A DO P2016000024A
Authority
DO
Dominican Republic
Prior art keywords
clopidogrel
acid
acetilsalicyl
understanding
layer
Prior art date
Application number
DO2016000024A
Other languages
English (en)
Inventor
Brenne Jean-Francois
Daste Georges
Edeline-Berlemont Julie
Fontaine Nicolas
Calligaris Frédérique
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49085055&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DOP2016000024(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of DOP2016000024A publication Critical patent/DOP2016000024A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/282—Organic compounds, e.g. fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

LA PRESENTE INVENCIÓN SE REFIERE A UN COMPRIMIDO QUE COMPRENDE UN NÚCLEO Y UNA CAPA EXTERNA, COMPRENDIENDO EL NÚCLEO ÁCIDO ACETILSALICÍLICO O UNA DE SUS SALES FARMACÉUTICAMENTE ACEPTABLES Y COMPRENDIENDO LA CAPA EXTERNA CLOPIDOGREL O UNA DE SUS SALES FARMACÉUTICAMENTE ACEPTABLES, ESTANDO SEPARADO EL NÚCLEO DE LA CAPA EXTERNA POR UN RECUBRIMIENTO DE TRES CAPAS COMPUESTO DE UNA CAPA GASTRORRESISTENTE INSERTADA ENTRE DOS CAPAS AISLANTES.
DO2016000024A 2013-08-02 2016-01-19 Comprimido farmacéutico que comprende ácido acetilsalicílico y clopidogrel DOP2016000024A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/FR2013/051874 WO2015015062A1 (fr) 2013-08-02 2013-08-02 Comprime pharmaceutique comprenant de l'acide acetylsalicylique et du clopidogrel
PCT/EP2014/066110 WO2015014766A1 (en) 2013-08-02 2014-07-25 Pharmaceutical tablet comprising acetylsalicylic acid and clopidogrel

Publications (1)

Publication Number Publication Date
DOP2016000024A true DOP2016000024A (es) 2016-03-30

Family

ID=49085055

Family Applications (1)

Application Number Title Priority Date Filing Date
DO2016000024A DOP2016000024A (es) 2013-08-02 2016-01-19 Comprimido farmacéutico que comprende ácido acetilsalicílico y clopidogrel

Country Status (17)

Country Link
EP (1) EP3027176B1 (es)
JP (1) JP5905165B2 (es)
KR (1) KR102243349B1 (es)
CN (1) CN105407877B (es)
AR (1) AR097193A1 (es)
BR (1) BR112016001822B1 (es)
CL (1) CL2016000143A1 (es)
CR (1) CR20160067A (es)
DO (1) DOP2016000024A (es)
ES (1) ES2648913T3 (es)
HK (1) HK1221649A1 (es)
MY (1) MY176793A (es)
PE (1) PE20160212A1 (es)
PH (1) PH12016500121A1 (es)
SG (1) SG11201600218SA (es)
TW (1) TWI642435B (es)
WO (2) WO2015015062A1 (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104800183B (zh) * 2015-04-14 2016-08-31 陕西必康制药集团控股有限公司 一种阿司匹林肠溶片及其制备方法和应用
CN108289849A (zh) * 2015-06-26 2018-07-17 韩国联合制药株式会社 莫沙必利与雷贝拉唑的复合制剂
WO2017037741A1 (en) * 2015-09-02 2017-03-09 Sun Pharmaceutical Industries Ltd Compact solid dosage form of aspirin and clopidogrel
CN107308157B (zh) * 2017-06-08 2020-02-21 广州白云山天心制药股份有限公司 一种含有氯吡格雷的复方口服固体制剂及其制备方法
WO2019030610A1 (en) * 2017-08-11 2019-02-14 Solutions In Innovative Research Pvt. Ltd. PHARMACEUTICAL COMPOSITIONS WITH DUAL DIRECTLY COMPRESSIBLE MEDICAMENT RELEASE
CN107669690A (zh) * 2017-10-23 2018-02-09 罗铭炽 一种含阿司匹林和氯吡格雷的片剂
CN107693524A (zh) * 2017-10-23 2018-02-16 罗铭炽 一种含阿司匹林和氯吡格雷的制备方法
CN109528668A (zh) * 2018-12-20 2019-03-29 华中药业股份有限公司 阿司匹林片及其制备方法
CN112587495A (zh) * 2020-12-14 2021-04-02 乐普药业股份有限公司 一种阿司匹林和硫酸氢氯吡格雷复方制剂及其制备方法
EP4091605A1 (en) 2021-05-19 2022-11-23 G.L. Pharma GmbH Pharmaceutical tablet comprising acetylsalicylic acid
KR20240050841A (ko) * 2022-10-12 2024-04-19 일양약품주식회사 클로피도그렐 및 일라프라졸을 포함하는 복합제제

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04346930A (ja) * 1991-05-25 1992-12-02 Sumitomo Pharmaceut Co Ltd 安定なアスピリン腸溶錠
FR2744918B1 (fr) * 1996-02-19 1998-05-07 Sanofi Sa Nouvelles associations de principes actifs contenant un derive de thieno(3,2-c)pyridine et un antithrombotique
FR2779726B1 (fr) 1998-06-15 2001-05-18 Sanofi Sa Forme polymorphe de l'hydrogenosulfate de clopidogrel
FR2792836B3 (fr) * 1999-04-30 2001-07-27 Sanofi Sa Composition pharmaceutique sous forme unitaire contenant de l'aspirine et de l'hydrogenosulfate de clopidogrel
CN101703513B (zh) * 2009-11-10 2014-04-23 沈阳药科大学 阿司匹林和氯吡格雷或其药学上可接受的盐的复方缓释制剂
CA2792232C (en) * 2010-03-11 2014-07-15 Wockhardt Limited A device for the manufacture of a dosage form with a hole and method of manufacture
CN101874786B (zh) * 2010-06-05 2012-04-25 浙江金华康恩贝生物制药有限公司 无溶剂挤出滚圆法制备阿司匹林肠溶制剂
KR20120068277A (ko) * 2010-12-17 2012-06-27 한미사이언스 주식회사 ＨＭＧ－ＣｏＡ 환원효소 억제제 및 아스피린을 포함하는 약제학적 복합제제
CA2848764A1 (en) * 2011-09-14 2013-03-21 Pozen Inc. Controlled dosing of clopidogrel with gastric acid inhibition therapies
KR101675501B1 (ko) * 2011-11-02 2016-11-14 한국유나이티드제약 주식회사 클로피도그렐 및 아스피린의 복합제제
WO2013133620A1 (en) * 2012-03-09 2013-09-12 Yuhan Corporation Pharmaceutical composition comprising clopidogrel and aspirin and process for preparing the same

Also Published As

Publication number Publication date
EP3027176A1 (en) 2016-06-08
WO2015015062A1 (fr) 2015-02-05
CN105407877B (zh) 2019-05-07
SG11201600218SA (en) 2016-02-26
CN105407877A (zh) 2016-03-16
CR20160067A (es) 2016-04-01
EP3027176B1 (en) 2017-08-23
TW201601721A (zh) 2016-01-16
TWI642435B (zh) 2018-12-01
HK1221649A1 (zh) 2017-06-09
BR112016001822B1 (pt) 2022-10-18
PH12016500121B1 (en) 2016-04-25
JP5905165B2 (ja) 2016-04-20
PH12016500121A1 (en) 2016-04-25
KR102243349B1 (ko) 2021-04-21
JP2015526498A (ja) 2015-09-10
CL2016000143A1 (es) 2016-06-24
WO2015014766A1 (en) 2015-02-05
AR097193A1 (es) 2016-02-24
MY176793A (en) 2020-08-21
PE20160212A1 (es) 2016-05-09
ES2648913T3 (es) 2018-01-08
KR20160037967A (ko) 2016-04-06
BR112016001822A2 (pt) 2017-08-01

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