SV2010003769A - Derivados de dibenzotiazepina y sus usos - Google Patents

Derivados de dibenzotiazepina y sus usos

Info

Publication number
SV2010003769A
SV2010003769A SV2010003769A SV2010003769A SV2010003769A SV 2010003769 A SV2010003769 A SV 2010003769A SV 2010003769 A SV2010003769 A SV 2010003769A SV 2010003769 A SV2010003769 A SV 2010003769A SV 2010003769 A SV2010003769 A SV 2010003769A
Authority
SV
El Salvador
Prior art keywords
disorder
dibenzotiazepina
derivatives
chronicostrynostrostrynostrostrostry
understand
Prior art date
Application number
SV2010003769A
Other languages
English (en)
Spanish (es)
Inventor
Dean Brown
James R Damewood
Phil Edwards
James Hulsizer
James Campbell Muir
Jr M Edward Pierson
Ashokkumar Bhikkappa Shenvi
Steven Wesolowski
Dan Widzowski
Michael R Wood
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41431860&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SV2010003769(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of SV2010003769A publication Critical patent/SV2010003769A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/554Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D281/00Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02Seven-membered rings
    • C07D281/04Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/12Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D281/16[b, f]-condensed

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Steroid Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
SV2010003769A 2008-06-20 2010-12-20 Derivados de dibenzotiazepina y sus usos SV2010003769A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US7441708P 2008-06-20 2008-06-20

Publications (1)

Publication Number Publication Date
SV2010003769A true SV2010003769A (es) 2011-05-20

Family

ID=41431860

Family Applications (1)

Application Number Title Priority Date Filing Date
SV2010003769A SV2010003769A (es) 2008-06-20 2010-12-20 Derivados de dibenzotiazepina y sus usos

Country Status (37)

Country Link
US (3) US20110160184A1 (enExample)
EP (1) EP2307389B1 (enExample)
JP (2) JP5468068B2 (enExample)
KR (1) KR20110019781A (enExample)
CN (1) CN102131791B (enExample)
AR (1) AR072200A1 (enExample)
AU (1) AU2009260905B2 (enExample)
BR (1) BRPI0914231A2 (enExample)
CA (1) CA2728675A1 (enExample)
CL (1) CL2010001471A1 (enExample)
CR (1) CR11860A (enExample)
CU (1) CU23884B1 (enExample)
CY (1) CY1113845T1 (enExample)
DK (1) DK2307389T3 (enExample)
DO (1) DOP2010000393A (enExample)
EA (1) EA201001889A1 (enExample)
EC (1) ECSP10010698A (enExample)
ES (1) ES2402084T3 (enExample)
HN (1) HN2010002683A (enExample)
HR (1) HRP20130234T1 (enExample)
IL (2) IL210081A (enExample)
ME (1) ME01516B (enExample)
MX (1) MX2010014203A (enExample)
MY (1) MY157518A (enExample)
NI (1) NI201000224A (enExample)
NZ (1) NZ590616A (enExample)
PE (1) PE20110029A1 (enExample)
PL (1) PL2307389T3 (enExample)
PT (1) PT2307389E (enExample)
RS (1) RS52703B (enExample)
SI (1) SI2307389T1 (enExample)
SV (1) SV2010003769A (enExample)
TW (1) TWI488854B (enExample)
UA (1) UA105903C2 (enExample)
UY (1) UY31919A (enExample)
WO (1) WO2009154563A1 (enExample)
ZA (1) ZA201100488B (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2307389T3 (pl) * 2008-06-20 2013-05-31 Astrazeneca Ab Pochodne dibenzotiazepiny i ich zastosowanie
WO2015021548A1 (en) * 2013-08-12 2015-02-19 Graphite Software Corporation Secure authentication and switching to encrypted domains
CN103524455A (zh) * 2013-10-30 2014-01-22 苏州敬业医药化工有限公司 一种制备2-氯-二苯并[b,f][1,4]硫氮杂卓-11-[10H]酮的方法
EP3072320A4 (en) 2013-11-21 2017-05-24 Graphite Software Corporation Managed domains for remote content and configuration control on mobile information devices
CN104447615A (zh) * 2014-02-28 2015-03-25 广东东阳光药业有限公司 喹硫平中间体的制备方法
CN120981447A (zh) * 2023-03-08 2025-11-18 法兰克福大学 Slack激活化合物及其医学用途
EP4428132A1 (en) * 2023-03-08 2024-09-11 Johann-Wolfgang-Goethe-Universität Frankfurt am Main Slack-activating compounds and their medical use

Family Cites Families (69)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL294355A (enExample)
NL293201A (enExample)
DE1620703B2 (de) * 1960-08-16 1976-11-25 Ausscheidung aus: 12 80 879 Dr. A. Wander AG, Bern 11-basisch substituierte dibenzo eckige klammer auf b,f eckige klammer zu-eckige klammer auf 1,4 eckige klammer zu-thiazepine
CH422793A (de) 1961-07-20 1966-10-31 Wander Ag Dr A Verfahren zur Herstellung 11-basisch substituierter Dibenzo(b,f) (1,4)thiazepine
DE1620711A1 (de) * 1962-05-25 1970-06-04 Wander Ag Dr A Verfahren zur Herstellung 11-basisch substituierter 5H-Dibenzo[b,e][1,4]diazepine
CH476743A (de) 1962-06-08 1969-08-15 Wander Ag Dr A Verfahren zur Herstellung von Amidinen der Dibenzo (b,e) (1,4)-diazepin-Reihe
NL140242B (nl) * 1963-03-01 1973-11-15 Wander Ag Dr A Werkwijze voor het bereiden van op de 11-plaats door een basische groep gesubstitueerde dibenz (b.f.)(1.4) oxazepinen.
BE632120A (enExample) 1963-05-09
US3908010A (en) * 1967-03-22 1975-09-23 Wander Ag Dr A Basically substituted heterocycles as anti-emetics
US3884920A (en) * 1967-07-14 1975-05-20 Sandoz Ag 11-Basically substituted dibenz {8 b,f{9 {0 {8 1,4{9 {0 oxazepines
US3683034A (en) * 1963-09-27 1972-08-08 Upjohn Co Process for the preparation of substituted hydroquinones
US3412193A (en) * 1965-12-13 1968-11-19 American Cyanamid Co 11-(4-methyl-1-piperazinyl)dibenz[b, f][1, 4]oxazepines or thiazepines for controlling fertility
AT278805B (de) * 1966-01-17 1970-02-10 American Cyanamid Co Verfahren zur herstellung von oxazepinen und thiazepinen
NL6715650A (enExample) 1966-12-16 1968-06-17
US3852446A (en) * 1967-03-13 1974-12-03 Sandoz Ag Organic compounds in treatment of psychotic disturbances
US3539573A (en) 1967-03-22 1970-11-10 Jean Schmutz 11-basic substituted dibenzodiazepines and dibenzothiazepines
US3758479A (en) * 1967-03-22 1973-09-11 Sandoz Ag Nitro and sulphamoyl substituted dibenzodiazepines
US3962248A (en) * 1972-04-04 1976-06-08 Sandoz, Inc. Process for making 11-piperazino-diazepines, oxazepines, thiazepines and azepines
CH569730A5 (enExample) * 1972-04-04 1975-11-28 Wander Ag Dr A
GB8607684D0 (en) * 1986-03-27 1986-04-30 Ici America Inc Thiazepine compounds
GB8705574D0 (en) 1987-03-10 1987-04-15 Ici Plc Preparation of thiazepine compound
JPH04211071A (ja) 1990-03-05 1992-08-03 Hokuriku Seiyaku Co Ltd 多環式化合物
JPH0565257A (ja) 1991-07-05 1993-03-19 Hokuriku Seiyaku Co Ltd 多環式化合物及びその用途
US5750566A (en) * 1994-08-12 1998-05-12 Eli Lilly And Company Synthetic excitatory amino acids
DE69516524T2 (de) 1994-08-24 2001-01-18 Astrazeneca Ab, Soedertaelje Therapeutisch verwendbare spiro-azabicyclische verbindungen
US5602121A (en) * 1994-12-12 1997-02-11 Allelix Biopharmaceuticals, Inc. Alkyl-substituted compounds having dopamine receptor affinity
SE9504661D0 (sv) 1995-12-22 1995-12-22 Astra Pharma Inc New compounds
SE9600683D0 (sv) 1996-02-23 1996-02-23 Astra Ab Azabicyclic esters of carbamic acids useful in therapy
AR013184A1 (es) 1997-07-18 2000-12-13 Astrazeneca Ab Aminas heterociclicas espiroazobiciclicas, composicion farmaceutica, uso de dichas aminas para preparar medicamentos y metodo de tratamiento o profilaxis
SE9702799D0 (sv) 1997-07-25 1997-07-25 Astra Ab New compounds
AU5489299A (en) * 1998-08-18 2000-03-14 Sepracor, Inc. Use of hydroxyrisperidone for the manufacture of a medicament for the treatment and prevention of psychoses, emesis and symptoms of withdrawal from alcohol and nicotine
SE9900100D0 (sv) 1999-01-15 1999-01-15 Astra Ab New compounds
US6703371B1 (en) 1999-07-28 2004-03-09 Oswald Wiss Preparations for reducing oxygen consumption during physical efforts
SE9903760D0 (sv) 1999-10-18 1999-10-18 Astra Ab New compounds
SE0002729D0 (sv) 2000-07-20 2000-07-20 Astrazeneca Ab Novel compound form
WO2002060870A2 (en) 2000-11-17 2002-08-08 Adolor Corporation Delta agonist analgesics
IL139975A0 (en) 2000-11-29 2002-02-10 Univ Ramot Anti proliferative drugs
DE60230869D1 (de) 2001-05-18 2009-03-05 Astrazeneca Ab 4-(phenylpiperazinylmethyl) benzamidderivate und deren verwendung zur behandlung von schmerzen, angst oder gastrointestinalen störungen
EP1397366B1 (en) 2001-06-01 2007-02-07 AstraZeneca AB Novel ligand for nicotinic acetylcholine receptors useful in therapy
SG152907A1 (en) * 2001-07-09 2009-06-29 Combinatorx Inc Combinations for the treatment of inflammatory disorders
US7544681B2 (en) 2001-09-27 2009-06-09 Ramot At Tel Aviv University Ltd. Conjugated psychotropic drugs and uses thereof
KR20090130150A (ko) 2001-09-27 2009-12-17 라모트 앳 텔 아비브 유니버시티 리미티드 접합된 항-정신병 약물 및 그의 용도
ES2348282T3 (es) 2002-04-18 2010-12-02 Astrazeneca Ab Compuestos de tienilo.
MXPA04010191A (es) 2002-04-18 2005-02-03 Astrazeneca Ab Compuestos de furilo.
BR0309345A (pt) 2002-04-18 2005-02-15 Astrazeneca Ab Composto ou sais farmaceuticamente aceitáveis do mesmo, composição farmacêutica, uso de um composto, e, métodos de tratamento ou profilaxia de doenças ou condições humanas, de distúrbios psicóticos ou de distúrbios de dano intelectual, e de jetlag, interrupção do hábito de fumar, dependência de nicotina, ânsias, dor e colite ulcerativa
SE0202465D0 (sv) 2002-08-14 2002-08-14 Astrazeneca Ab New compounds
SE0202430D0 (sv) 2002-08-14 2002-08-14 Astrazeneca Ab New Compounds
SE0202598D0 (sv) 2002-09-02 2002-09-02 Astrazeneca Ab Alpha-7 Nicotinic receptor agonists and statins in combination
CN1681388A (zh) 2002-09-18 2005-10-12 Fmc有限公司 三环衍生物杀虫剂
BR0317528A (pt) 2002-12-20 2005-11-22 Basf Ag Uso dos compostos, métodos para o controle de insetos, aracnìdeos ou nematodos, e para a proteção de plantas em crescimento contra o ataque ou a infestação por insetos, aracnìdeos ou nematodos, compostos, e, composições
EP1589974A2 (en) * 2003-01-23 2005-11-02 Acadia Pharmaceuticals Inc. Use of n-desmethylclozapine to treat human neuropsychiatric disease
WO2004076431A1 (en) 2003-02-22 2004-09-10 Teva Pharmaceutical Industries Ltd. Synthesis of quetiapine and pharmaceutically acceptable salts thereof
DE10310196A1 (de) 2003-03-06 2004-09-23 Rina-Netzwerk Rna Technologien Gmbh Verwendung eines trizyklischen Antidepressivums zur Förderung der Endozytose
CA2527170A1 (en) 2003-04-15 2004-10-28 Astrazeneca Ab Therapeutic compounds
US20060217366A1 (en) * 2003-07-02 2006-09-28 Astrazeneca Ab Method of treating schizophrenia and other disorders
PL195728B1 (pl) 2003-07-18 2007-10-31 Helm Ag Sposób wytwarzania 11-(1-piperazynylo)dibenzo[b,f][1,4]tiazepiny
RU2394030C2 (ru) * 2003-12-22 2010-07-10 Акадиа Фармасьютикалз Инк. АМИНОЗАМЕЩЕННЫЕ АНАЛОГИ ДИАРИЛ [a,d] ЦИКЛОГЕПТЕНА В КАЧЕСТВЕ МУСКАРИНОВЫХ АГОНИСТОВ И СПОСОБЫ ЛЕЧЕНИЯ ПСИХОНЕВРОЛОГИЧЕСКИХ РАССТРОЙСТВ
PL1696931T3 (pl) 2003-12-22 2009-10-30 Acadia Pharm Inc Aminopodstawione analogi diarylo[A,D]cykloheptenowe jako agoniści receptorów muskarynowych i sposoby leczenia chorób neuropsychiatrycznych
US20060063754A1 (en) * 2004-09-21 2006-03-23 Edgar Dale M Methods of treating a sleep disorder
BRPI0517423A (pt) 2004-12-27 2008-10-07 Astrazeneca Ab composto, composição farmacêutica, método para o tratamento ou prevenção de distúrbios neurológicos e psiquiátricos associados com disfunção do glutamato em um animal, e, uso em um composto
WO2006073360A1 (en) * 2005-01-07 2006-07-13 Astrazeneca Ab NEW USE OF 11-PIPERAZIN-1-YLDIBENZO [b,f] [1,4] THIAZEPINE OR ITS PHARMACEUTICALLY ACCEPTABLE SALT AND TO ORAL PHARMACEUTICAL COMPOSITIONS
EP1865962A2 (en) * 2005-04-04 2007-12-19 Arcadia Pharmaceuticals Inc. Use of n-desmethylclozapine and related compounds as dopamine stabilizing agents
US20070105836A1 (en) * 2005-10-31 2007-05-10 Lars Pettersson Prodrugs of muscarinic agonists and methods of treatment of neuropsychiatric disorders
EP2099459A4 (en) 2006-12-20 2011-04-27 Astrazeneca Ab COMPOUNDS AND USES THEREOF
WO2008100715A1 (en) 2007-02-09 2008-08-21 Astrazeneca Ab Aza-isoindolones and their use as metabotropic glutamate receptor potentiators - 613
US7491871B2 (en) 2007-04-25 2009-02-17 Stine Seed Farm, Inc. Soybean cultivar S060299
TWI417100B (zh) 2007-06-07 2013-12-01 Astrazeneca Ab 二唑衍生物及其作為代謝型麩胺酸受體增效劑-842之用途
TW200911255A (en) 2007-06-07 2009-03-16 Astrazeneca Ab Metabotropic glutamate receptor oxadiazole ligands and their use as potentiators-841
PL2307389T3 (pl) * 2008-06-20 2013-05-31 Astrazeneca Ab Pochodne dibenzotiazepiny i ich zastosowanie

Also Published As

Publication number Publication date
CY1113845T1 (el) 2016-07-27
AU2009260905A1 (en) 2009-12-23
NI201000224A (es) 2012-03-19
CN102131791B (zh) 2014-12-24
CL2010001471A1 (es) 2011-05-06
CU20100252A7 (es) 2011-11-15
PL2307389T3 (pl) 2013-05-31
US20090318415A1 (en) 2009-12-24
CA2728675A1 (en) 2009-12-23
ECSP10010698A (es) 2011-01-31
RS52703B (sr) 2013-08-30
IL210081A0 (en) 2011-02-28
EP2307389B1 (en) 2013-01-23
JP2011524898A (ja) 2011-09-08
CN102131791A (zh) 2011-07-20
EP2307389A4 (en) 2012-04-11
NZ590616A (en) 2012-09-28
PE20110029A1 (es) 2011-02-11
DK2307389T3 (da) 2013-04-02
EP2307389A1 (en) 2011-04-13
ES2402084T3 (es) 2013-04-26
MY157518A (en) 2016-06-15
BRPI0914231A2 (pt) 2015-11-03
US8653257B2 (en) 2014-02-18
HK1156308A1 (en) 2012-06-08
UA105903C2 (uk) 2014-07-10
US20120202991A1 (en) 2012-08-09
DOP2010000393A (es) 2011-01-31
AR072200A1 (es) 2010-08-11
HN2010002683A (es) 2013-01-15
EA201001889A1 (ru) 2011-08-30
IL229560A0 (en) 2014-01-30
JP5468068B2 (ja) 2014-04-09
SI2307389T1 (sl) 2013-04-30
CU23884B1 (es) 2013-04-19
US8158618B2 (en) 2012-04-17
KR20110019781A (ko) 2011-02-28
JP2014098006A (ja) 2014-05-29
UY31919A (es) 2010-01-29
ME01516B (me) 2014-04-20
WO2009154563A1 (en) 2009-12-23
CR11860A (es) 2011-02-25
ZA201100488B (en) 2011-10-26
PT2307389E (pt) 2013-03-28
MX2010014203A (es) 2011-02-22
US20110160184A1 (en) 2011-06-30
TW201002702A (en) 2010-01-16
TWI488854B (zh) 2015-06-21
IL210081A (en) 2013-12-31
AU2009260905B2 (en) 2012-08-23
IL229560A (en) 2015-07-30
HRP20130234T1 (hr) 2013-04-30

Similar Documents

Publication Publication Date Title
CO6761389A2 (es) Inhibidores de nampt y rock
UY32585A (es) Nuevos derivados del indazol utiles como inhibidores de la familia fosfoinositida 3´oh quinasa
CU20110145A7 (es) Derivados de sulfonamida
NI201100166A (es) Derivados de benzofuranilo utilizados como inhibidores de glucoquinasa
DOP2016000085A (es) Amino-heteroaril-benzamidas como inhibidores de cinasa
SV2010003769A (es) Derivados de dibenzotiazepina y sus usos
CR20170384A (es) Derivados de nucleosidos sustituidos utiles como agentes antineoplasicos
CR11757A (es) Compuestos de triazina como inhibidores mtor y quinasa pi3
NI201600058A (es) Compuestos derivados de piridilo bicíclicos fusionados a anillo como inhibidores de fgfr4
CO6341581A2 (es) Derivados de heteroarilo como inhibidores de dgat1
NI201500120A (es) Compuestos de biaril - amida como inhibidores de cinasa
UY35617A (es) Inhibidores de la fosfatidilinositol 3-quinasa
UY32809A (es) Compuestos y composiciones como inhibidores de cinasa s y k
MX2015012456A (es) Compuestos heterociclicos y usos de los mismos.
SV2010003777A (es) Compuestos organicos
CO6430459A2 (es) Derivados de prolina como inhibidores de catepsina
CU20140072A7 (es) Derivados de dihidro-oxazina y dihidro-pirido-oxazina
CR11629A (es) INHIBIDORES HETEROCICLICOS DE ESTEAROIL-CoA- DESATURASA.
DOP2016000120A (es) Nuevos inhibidores de dgat2
MX2018006802A (es) Derivados de fenilo como agonistas del receptor de canabinoides 2.
CL2017000827A1 (es) Inhibidores de aldosterona sintasa
CL2023002486A1 (es) Compuestos heterocíclicos como inhibidores de delta-5 desaturasa y métodos de uso
ECSP12011837A (es) Derivados de pirazol que modulan la estearoil-coa-desaturasa
PE20151669A1 (es) Compuestos de azetidiniloxifenilpirrolidina
CL2018003158A1 (es) Derivados de piridinilo, composiciones farmacéuticas y sus usos como inhibidores aoc3.

Legal Events

Date Code Title Description
FD Lapse