EA201001889A1 - Производные дибензотиазепина и их применение - Google Patents

Производные дибензотиазепина и их применение

Info

Publication number
EA201001889A1
EA201001889A1 EA201001889A EA201001889A EA201001889A1 EA 201001889 A1 EA201001889 A1 EA 201001889A1 EA 201001889 A EA201001889 A EA 201001889A EA 201001889 A EA201001889 A EA 201001889A EA 201001889 A1 EA201001889 A1 EA 201001889A1
Authority
EA
Eurasian Patent Office
Prior art keywords
disorder
dibenzothiazepine
derivatives
application
compounds
Prior art date
Application number
EA201001889A
Other languages
English (en)
Inventor
Дин Браун
Джеймс Р. Деймвуд
Фил Эдвардс
Джеймс Халсайзер
Джеймс Кемпбелл Мьюр
мл. М. Эдвард Пирсон
Ашоккумар Бхиккаппа Шенви
Стивен Весоловски
Дэн Видзовски
Майкл Вуд
Original Assignee
Астразенека Аб
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41431860&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA201001889(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Астразенека Аб filed Critical Астразенека Аб
Publication of EA201001889A1 publication Critical patent/EA201001889A1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D281/16—[b, f]-condensed

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Steroid Compounds (AREA)

Abstract

Соединения нижеследующей формулы, где Z является таким, как раскрыто в описании, их фармацевтически приемлемые соли, композиции, содержащие их, и способы лечения биполярного расстройства, тревожного расстройства, расстройства настроения или шизофрении либо другого психотического расстройства указанными соединениями.
EA201001889A 2008-06-20 2009-06-18 Производные дибензотиазепина и их применение EA201001889A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7441708P 2008-06-20 2008-06-20
PCT/SE2009/050763 WO2009154563A1 (en) 2008-06-20 2009-06-18 Dibenzothiazepine derivatives and use thereof

Publications (1)

Publication Number Publication Date
EA201001889A1 true EA201001889A1 (ru) 2011-08-30

Family

ID=41431860

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201001889A EA201001889A1 (ru) 2008-06-20 2009-06-18 Производные дибензотиазепина и их применение

Country Status (38)

Country Link
US (3) US20110160184A1 (ru)
EP (1) EP2307389B1 (ru)
JP (2) JP5468068B2 (ru)
KR (1) KR20110019781A (ru)
CN (1) CN102131791B (ru)
AR (1) AR072200A1 (ru)
AU (1) AU2009260905B2 (ru)
BR (1) BRPI0914231A2 (ru)
CA (1) CA2728675A1 (ru)
CL (1) CL2010001471A1 (ru)
CR (1) CR11860A (ru)
CU (1) CU23884B1 (ru)
CY (1) CY1113845T1 (ru)
DK (1) DK2307389T3 (ru)
DO (1) DOP2010000393A (ru)
EA (1) EA201001889A1 (ru)
EC (1) ECSP10010698A (ru)
ES (1) ES2402084T3 (ru)
HK (1) HK1156308A1 (ru)
HN (1) HN2010002683A (ru)
HR (1) HRP20130234T1 (ru)
IL (2) IL210081A (ru)
ME (1) ME01516B (ru)
MX (1) MX2010014203A (ru)
MY (1) MY157518A (ru)
NI (1) NI201000224A (ru)
NZ (1) NZ590616A (ru)
PE (1) PE20110029A1 (ru)
PL (1) PL2307389T3 (ru)
PT (1) PT2307389E (ru)
RS (1) RS52703B (ru)
SI (1) SI2307389T1 (ru)
SV (1) SV2010003769A (ru)
TW (1) TWI488854B (ru)
UA (1) UA105903C2 (ru)
UY (1) UY31919A (ru)
WO (1) WO2009154563A1 (ru)
ZA (1) ZA201100488B (ru)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2307389T3 (da) * 2008-06-20 2013-04-02 Astrazeneca Ab Dibenzothiazepinderivat og anvendelser deraf
KR20160043029A (ko) * 2013-08-12 2016-04-20 그라파이트 소프트웨어 코포레이션 보안 인증 및 암호화된 도메인들로의 스위칭
CN103524455A (zh) * 2013-10-30 2014-01-22 苏州敬业医药化工有限公司 一种制备2-氯-二苯并[b,f][1,4]硫氮杂卓-11-[10H]酮的方法
CA2931289C (en) 2013-11-21 2023-10-17 Graphite Software Corporation Managed domains for remote content and configuration control on mobile information devices
CN104447615A (zh) * 2014-02-28 2015-03-25 广东东阳光药业有限公司 喹硫平中间体的制备方法

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Also Published As

Publication number Publication date
ME01516B (me) 2014-04-20
EP2307389B1 (en) 2013-01-23
AU2009260905B2 (en) 2012-08-23
MX2010014203A (es) 2011-02-22
US20090318415A1 (en) 2009-12-24
AU2009260905A1 (en) 2009-12-23
TWI488854B (zh) 2015-06-21
MY157518A (en) 2016-06-15
CY1113845T1 (el) 2016-07-27
JP5468068B2 (ja) 2014-04-09
CR11860A (es) 2011-02-25
UA105903C2 (ru) 2014-07-10
US20120202991A1 (en) 2012-08-09
NZ590616A (en) 2012-09-28
RS52703B (en) 2013-08-30
BRPI0914231A2 (pt) 2015-11-03
CA2728675A1 (en) 2009-12-23
KR20110019781A (ko) 2011-02-28
JP2014098006A (ja) 2014-05-29
JP2011524898A (ja) 2011-09-08
UY31919A (es) 2010-01-29
DOP2010000393A (es) 2011-01-31
IL210081A0 (en) 2011-02-28
CN102131791A (zh) 2011-07-20
HRP20130234T1 (hr) 2013-04-30
AR072200A1 (es) 2010-08-11
US8158618B2 (en) 2012-04-17
NI201000224A (es) 2012-03-19
HN2010002683A (es) 2013-01-15
EP2307389A4 (en) 2012-04-11
CN102131791B (zh) 2014-12-24
TW201002702A (en) 2010-01-16
CL2010001471A1 (es) 2011-05-06
WO2009154563A1 (en) 2009-12-23
HK1156308A1 (en) 2012-06-08
CU20100252A7 (es) 2011-11-15
CU23884B1 (es) 2013-04-19
ES2402084T3 (es) 2013-04-26
IL229560A (en) 2015-07-30
ECSP10010698A (es) 2011-01-31
US8653257B2 (en) 2014-02-18
PE20110029A1 (es) 2011-02-11
IL229560A0 (en) 2014-01-30
IL210081A (en) 2013-12-31
SV2010003769A (es) 2011-05-20
EP2307389A1 (en) 2011-04-13
ZA201100488B (en) 2011-10-26
PT2307389E (pt) 2013-03-28
PL2307389T3 (pl) 2013-05-31
SI2307389T1 (sl) 2013-04-30
US20110160184A1 (en) 2011-06-30
DK2307389T3 (da) 2013-04-02

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