UY31919A - Derivados de dibenzotiazepinas y sus usos-424 - Google Patents
Derivados de dibenzotiazepinas y sus usos-424Info
- Publication number
- UY31919A UY31919A UY0001031919A UY31919A UY31919A UY 31919 A UY31919 A UY 31919A UY 0001031919 A UY0001031919 A UY 0001031919A UY 31919 A UY31919 A UY 31919A UY 31919 A UY31919 A UY 31919A
- Authority
- UY
- Uruguay
- Prior art keywords
- dibenzotiazepinas
- derivatives
- disorder
- compounds
- schizophrenia
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D281/02—Seven-membered rings
- C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
- C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D281/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D281/16—[b, f]-condensed
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Steroid Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
Compuestos de la siguiente fórmula: donde Z es como se describen en la memoria descriptiva, sales farmacéuticamente aceptables de los mismos, composiciones que los comprenden, y procedimientos para tratar el trastorno bipolar, un trastorno de ansiedad, un trastorno del humor o esquizofrenia, u otros trastornos psicóticos, con los referidos compuestos.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US7441708P | 2008-06-20 | 2008-06-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
UY31919A true UY31919A (es) | 2010-01-29 |
Family
ID=41431860
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UY0001031919A UY31919A (es) | 2008-06-20 | 2009-06-18 | Derivados de dibenzotiazepinas y sus usos-424 |
Country Status (38)
Country | Link |
---|---|
US (3) | US20110160184A1 (es) |
EP (1) | EP2307389B1 (es) |
JP (2) | JP5468068B2 (es) |
KR (1) | KR20110019781A (es) |
CN (1) | CN102131791B (es) |
AR (1) | AR072200A1 (es) |
AU (1) | AU2009260905B2 (es) |
BR (1) | BRPI0914231A2 (es) |
CA (1) | CA2728675A1 (es) |
CL (1) | CL2010001471A1 (es) |
CR (1) | CR11860A (es) |
CU (1) | CU23884B1 (es) |
CY (1) | CY1113845T1 (es) |
DK (1) | DK2307389T3 (es) |
DO (1) | DOP2010000393A (es) |
EA (1) | EA201001889A1 (es) |
EC (1) | ECSP10010698A (es) |
ES (1) | ES2402084T3 (es) |
HK (1) | HK1156308A1 (es) |
HN (1) | HN2010002683A (es) |
HR (1) | HRP20130234T1 (es) |
IL (2) | IL210081A (es) |
ME (1) | ME01516B (es) |
MX (1) | MX2010014203A (es) |
MY (1) | MY157518A (es) |
NI (1) | NI201000224A (es) |
NZ (1) | NZ590616A (es) |
PE (1) | PE20110029A1 (es) |
PL (1) | PL2307389T3 (es) |
PT (1) | PT2307389E (es) |
RS (1) | RS52703B (es) |
SI (1) | SI2307389T1 (es) |
SV (1) | SV2010003769A (es) |
TW (1) | TWI488854B (es) |
UA (1) | UA105903C2 (es) |
UY (1) | UY31919A (es) |
WO (1) | WO2009154563A1 (es) |
ZA (1) | ZA201100488B (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI488854B (zh) * | 2008-06-20 | 2015-06-21 | Astrazeneca Ab | 二苯并噻氮呯衍生物及其用途 |
US20160205082A1 (en) * | 2013-08-12 | 2016-07-14 | Graphite Software Corporation | Secure authentication and switching to encrypted domains |
CN103524455A (zh) * | 2013-10-30 | 2014-01-22 | 苏州敬业医药化工有限公司 | 一种制备2-氯-二苯并[b,f][1,4]硫氮杂卓-11-[10H]酮的方法 |
WO2015074150A1 (en) | 2013-11-21 | 2015-05-28 | Graphite Software Corporation | Managed domains for remote content and configuration control on mobile information devices |
CN104447615A (zh) * | 2014-02-28 | 2015-03-25 | 广东东阳光药业有限公司 | 喹硫平中间体的制备方法 |
Family Cites Families (69)
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NL294355A (es) | ||||
NL293201A (es) | ||||
DE1620703B2 (de) * | 1960-08-16 | 1976-11-25 | Ausscheidung aus: 12 80 879 Dr. A. Wander AG, Bern | 11-basisch substituierte dibenzo eckige klammer auf b,f eckige klammer zu-eckige klammer auf 1,4 eckige klammer zu-thiazepine |
CH422793A (de) | 1961-07-20 | 1966-10-31 | Wander Ag Dr A | Verfahren zur Herstellung 11-basisch substituierter Dibenzo(b,f) (1,4)thiazepine |
CH476753A (de) | 1962-06-08 | 1969-08-15 | Wander Ag Dr A | Verfahren zur Herstellung von 11-basisch substituierter Dibenzo(b,f)(1,4)thiazepine |
DE1620713A1 (de) * | 1962-05-25 | 1970-07-02 | Wander Ag Dr A | Verfahren zur Herstellung von 11-basisch substituierter Dibenzo[b,f][1,4]thiazepine |
NL140242B (nl) | 1963-03-01 | 1973-11-15 | Wander Ag Dr A | Werkwijze voor het bereiden van op de 11-plaats door een basische groep gesubstitueerde dibenz (b.f.)(1.4) oxazepinen. |
BE632120A (es) | 1963-05-09 | |||
US3683034A (en) | 1963-09-27 | 1972-08-08 | Upjohn Co | Process for the preparation of substituted hydroquinones |
US3908010A (en) | 1967-03-22 | 1975-09-23 | Wander Ag Dr A | Basically substituted heterocycles as anti-emetics |
US3884920A (en) | 1967-07-14 | 1975-05-20 | Sandoz Ag | 11-Basically substituted dibenz {8 b,f{9 {0 {8 1,4{9 {0 oxazepines |
US3412193A (en) | 1965-12-13 | 1968-11-19 | American Cyanamid Co | 11-(4-methyl-1-piperazinyl)dibenz[b, f][1, 4]oxazepines or thiazepines for controlling fertility |
US3444169A (en) | 1966-01-17 | 1969-05-13 | American Cyanamid Co | Process for 11 - aminodibenz(b,f)(1,4)oxazepines and analogous thiazepines |
NL6715650A (es) | 1966-12-16 | 1968-06-17 | ||
US3852446A (en) | 1967-03-13 | 1974-12-03 | Sandoz Ag | Organic compounds in treatment of psychotic disturbances |
US3539573A (en) * | 1967-03-22 | 1970-11-10 | Jean Schmutz | 11-basic substituted dibenzodiazepines and dibenzothiazepines |
US3758479A (en) | 1967-03-22 | 1973-09-11 | Sandoz Ag | Nitro and sulphamoyl substituted dibenzodiazepines |
CH569730A5 (es) * | 1972-04-04 | 1975-11-28 | Wander Ag Dr A | |
US3962248A (en) * | 1972-04-04 | 1976-06-08 | Sandoz, Inc. | Process for making 11-piperazino-diazepines, oxazepines, thiazepines and azepines |
GB8607684D0 (en) | 1986-03-27 | 1986-04-30 | Ici America Inc | Thiazepine compounds |
GB8705574D0 (en) | 1987-03-10 | 1987-04-15 | Ici Plc | Preparation of thiazepine compound |
JPH04211071A (ja) * | 1990-03-05 | 1992-08-03 | Hokuriku Seiyaku Co Ltd | 多環式化合物 |
JPH0565257A (ja) | 1991-07-05 | 1993-03-19 | Hokuriku Seiyaku Co Ltd | 多環式化合物及びその用途 |
US5661184A (en) | 1994-08-12 | 1997-08-26 | Eli Lilly And Company | Psychiatric agents |
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SE9504661D0 (sv) | 1995-12-22 | 1995-12-22 | Astra Pharma Inc | New compounds |
SE9600683D0 (sv) | 1996-02-23 | 1996-02-23 | Astra Ab | Azabicyclic esters of carbamic acids useful in therapy |
AR013184A1 (es) | 1997-07-18 | 2000-12-13 | Astrazeneca Ab | Aminas heterociclicas espiroazobiciclicas, composicion farmaceutica, uso de dichas aminas para preparar medicamentos y metodo de tratamiento o profilaxis |
SE9702799D0 (sv) | 1997-07-25 | 1997-07-25 | Astra Ab | New compounds |
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SE9900100D0 (sv) | 1999-01-15 | 1999-01-15 | Astra Ab | New compounds |
JP2003505505A (ja) | 1999-07-28 | 2003-02-12 | オスヴァルト・ヴィス | 運動時の酸素消費を低下するための製剤 |
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SE0002729D0 (sv) | 2000-07-20 | 2000-07-20 | Astrazeneca Ab | Novel compound form |
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SI1395567T1 (sl) | 2001-05-18 | 2009-04-30 | Astrazeneca Ab | 4-(fenil-piperazinil-metil)benzamidni derivati in njihova uporaba za zdravljenje bolečine, tesnobe ali gastrointestinalnih motenj |
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BR0309343A (pt) | 2002-04-18 | 2005-02-15 | Astrazeneca Ab | Composto, composição farmacêutica, uso de um composto, e, método de tratamento ou profilaxia de doenças ou condições humanas |
SE0202465D0 (sv) | 2002-08-14 | 2002-08-14 | Astrazeneca Ab | New compounds |
SE0202430D0 (sv) | 2002-08-14 | 2002-08-14 | Astrazeneca Ab | New Compounds |
SE0202598D0 (sv) | 2002-09-02 | 2002-09-02 | Astrazeneca Ab | Alpha-7 Nicotinic receptor agonists and statins in combination |
BR0314108A (pt) | 2002-09-18 | 2006-04-25 | Fmc Corp | derivados tricìclios inseticidas |
BR0317528A (pt) * | 2002-12-20 | 2005-11-22 | Basf Ag | Uso dos compostos, métodos para o controle de insetos, aracnìdeos ou nematodos, e para a proteção de plantas em crescimento contra o ataque ou a infestação por insetos, aracnìdeos ou nematodos, compostos, e, composições |
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DE10310196A1 (de) | 2003-03-06 | 2004-09-23 | Rina-Netzwerk Rna Technologien Gmbh | Verwendung eines trizyklischen Antidepressivums zur Förderung der Endozytose |
JP2006523707A (ja) | 2003-04-15 | 2006-10-19 | アストラゼネカ アクツィエボラーグ | 治療化合物 |
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PL195728B1 (pl) | 2003-07-18 | 2007-10-31 | Helm Ag | Sposób wytwarzania 11-(1-piperazynylo)dibenzo[b,f][1,4]tiazepiny |
RU2394030C2 (ru) * | 2003-12-22 | 2010-07-10 | Акадиа Фармасьютикалз Инк. | АМИНОЗАМЕЩЕННЫЕ АНАЛОГИ ДИАРИЛ [a,d] ЦИКЛОГЕПТЕНА В КАЧЕСТВЕ МУСКАРИНОВЫХ АГОНИСТОВ И СПОСОБЫ ЛЕЧЕНИЯ ПСИХОНЕВРОЛОГИЧЕСКИХ РАССТРОЙСТВ |
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KR20070106690A (ko) | 2004-12-27 | 2007-11-05 | 아스트라제네카 아베 | 피라졸론 화합물 및 대사성 글루타메이트 수용체길항제로서 그들의 용도 |
JP2008526839A (ja) * | 2005-01-07 | 2008-07-24 | アストラゼネカ・アクチエボラーグ | 11−ピペラジン−1−イルジベンゾ[b,f][1,4]チアゼピン又はその薬学的に許容される塩の新規な使用及び経口医薬組成物への新規な使用 |
US20060252744A1 (en) * | 2005-04-04 | 2006-11-09 | Burstein Ethan S | Use of N-desmethylclozapine and related compounds as dopamine stabilizing agents |
WO2007053618A1 (en) * | 2005-10-31 | 2007-05-10 | Acadia Pharmaceuticals Inc. | Prodrugs of muscarinic agonists and methods of treatment of neuropsychiatric disorders |
EP2099459A4 (en) | 2006-12-20 | 2011-04-27 | Astrazeneca Ab | COMPOUNDS AND USES THEREOF |
JP2010518104A (ja) | 2007-02-09 | 2010-05-27 | アストラゼネカ・アクチエボラーグ | アザ−イソインドロンおよび代謝型グルタミン酸レセプター増強剤−613としてのそれらの使用 |
US7491871B2 (en) | 2007-04-25 | 2009-02-17 | Stine Seed Farm, Inc. | Soybean cultivar S060299 |
TW200911255A (en) | 2007-06-07 | 2009-03-16 | Astrazeneca Ab | Metabotropic glutamate receptor oxadiazole ligands and their use as potentiators-841 |
TWI417100B (zh) | 2007-06-07 | 2013-12-01 | Astrazeneca Ab | 二唑衍生物及其作為代謝型麩胺酸受體增效劑-842之用途 |
TWI488854B (zh) * | 2008-06-20 | 2015-06-21 | Astrazeneca Ab | 二苯并噻氮呯衍生物及其用途 |
-
2009
- 2009-06-18 TW TW098120494A patent/TWI488854B/zh not_active IP Right Cessation
- 2009-06-18 RS RS20130109A patent/RS52703B/en unknown
- 2009-06-18 PL PL09766953T patent/PL2307389T3/pl unknown
- 2009-06-18 ES ES09766953T patent/ES2402084T3/es active Active
- 2009-06-18 NZ NZ590616A patent/NZ590616A/xx not_active IP Right Cessation
- 2009-06-18 MX MX2010014203A patent/MX2010014203A/es active IP Right Grant
- 2009-06-18 UY UY0001031919A patent/UY31919A/es not_active Application Discontinuation
- 2009-06-18 EA EA201001889A patent/EA201001889A1/ru unknown
- 2009-06-18 PT PT97669535T patent/PT2307389E/pt unknown
- 2009-06-18 DK DK09766953.5T patent/DK2307389T3/da active
- 2009-06-18 KR KR1020117001427A patent/KR20110019781A/ko not_active Application Discontinuation
- 2009-06-18 CA CA2728675A patent/CA2728675A1/en not_active Abandoned
- 2009-06-18 SI SI200930544T patent/SI2307389T1/sl unknown
- 2009-06-18 CN CN200980132601.5A patent/CN102131791B/zh not_active Expired - Fee Related
- 2009-06-18 UA UAA201015001A patent/UA105903C2/uk unknown
- 2009-06-18 PE PE2010001170A patent/PE20110029A1/es not_active Application Discontinuation
- 2009-06-18 AU AU2009260905A patent/AU2009260905B2/en not_active Ceased
- 2009-06-18 JP JP2011514540A patent/JP5468068B2/ja not_active Expired - Fee Related
- 2009-06-18 US US12/999,808 patent/US20110160184A1/en not_active Abandoned
- 2009-06-18 ME MEP-2013-27A patent/ME01516B/me unknown
- 2009-06-18 EP EP09766953A patent/EP2307389B1/en active Active
- 2009-06-18 BR BRPI0914231A patent/BRPI0914231A2/pt not_active IP Right Cessation
- 2009-06-18 MY MYPI2010006035A patent/MY157518A/en unknown
- 2009-06-18 WO PCT/SE2009/050763 patent/WO2009154563A1/en active Application Filing
- 2009-06-19 AR ARP090102240A patent/AR072200A1/es unknown
- 2009-06-19 US US12/487,725 patent/US8158618B2/en not_active Expired - Fee Related
-
2010
- 2010-12-16 IL IL210081A patent/IL210081A/en not_active IP Right Cessation
- 2010-12-17 CL CL2010001471A patent/CL2010001471A1/es unknown
- 2010-12-20 CR CR11860A patent/CR11860A/es unknown
- 2010-12-20 SV SV2010003769A patent/SV2010003769A/es not_active Application Discontinuation
- 2010-12-20 NI NI201000224A patent/NI201000224A/es unknown
- 2010-12-20 DO DO2010000393A patent/DOP2010000393A/es unknown
- 2010-12-20 HN HN2010002683A patent/HN2010002683A/es unknown
- 2010-12-20 CU CU20100252A patent/CU23884B1/es not_active IP Right Cessation
- 2010-12-20 EC EC2010010698A patent/ECSP10010698A/es unknown
-
2011
- 2011-01-19 ZA ZA2011/00488A patent/ZA201100488B/en unknown
- 2011-10-06 HK HK11110535.8A patent/HK1156308A1/xx not_active IP Right Cessation
-
2012
- 2012-04-12 US US13/445,347 patent/US8653257B2/en not_active Expired - Fee Related
-
2013
- 2013-03-19 HR HRP20130234AT patent/HRP20130234T1/hr unknown
- 2013-03-22 CY CY20131100246T patent/CY1113845T1/el unknown
- 2013-11-21 IL IL229560A patent/IL229560A/en not_active IP Right Cessation
-
2014
- 2014-01-27 JP JP2014011979A patent/JP2014098006A/ja active Pending
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