SU1602389A3 - Устройство дл длительного высвобождени лекарственного вещества в рубцово-сетчатом отделе желудка жвачных животных - Google Patents
Устройство дл длительного высвобождени лекарственного вещества в рубцово-сетчатом отделе желудка жвачных животных Download PDFInfo
- Publication number
- SU1602389A3 SU1602389A3 SU853853845A SU3853845A SU1602389A3 SU 1602389 A3 SU1602389 A3 SU 1602389A3 SU 853853845 A SU853853845 A SU 853853845A SU 3853845 A SU3853845 A SU 3853845A SU 1602389 A3 SU1602389 A3 SU 1602389A3
- Authority
- SU
- USSR - Soviet Union
- Prior art keywords
- stomach
- ruminants
- medicinal substance
- core
- sheets
- Prior art date
Links
- 239000012907 medicinal substance Substances 0.000 title claims 5
- 241000282849 Ruminantia Species 0.000 title claims 4
- 210000002784 stomach Anatomy 0.000 title claims 4
- 230000002035 prolonged effect Effects 0.000 title abstract 2
- OLOCXIJVDIVAHH-FXRZFVDSSA-N 2-hydroxypropane-1,2,3-tricarboxylic acid;1-methyl-2-[(e)-2-(3-methylthiophen-2-yl)ethenyl]-5,6-dihydro-4h-pyrimidine Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O.CN1CCCN=C1\C=C\C1=C(C)C=CS1 OLOCXIJVDIVAHH-FXRZFVDSSA-N 0.000 claims description 6
- 229920006254 polymer film Polymers 0.000 claims description 6
- KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 claims description 5
- NVEPPWDVLBMNMB-SNAWJCMRSA-N 1-methyl-2-[(e)-2-(3-methylthiophen-2-yl)ethenyl]-5,6-dihydro-4h-pyrimidine Chemical compound CN1CCCN=C1\C=C\C1=C(C)C=CS1 NVEPPWDVLBMNMB-SNAWJCMRSA-N 0.000 claims description 3
- 239000012792 core layer Substances 0.000 claims description 3
- 229960005121 morantel Drugs 0.000 claims description 3
- 239000008186 active pharmaceutical agent Substances 0.000 claims description 2
- 229940088679 drug related substance Drugs 0.000 claims description 2
- 150000002009 diols Chemical class 0.000 claims 1
- 239000012530 fluid Substances 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 238000013268 sustained release Methods 0.000 claims 1
- 239000012730 sustained-release form Substances 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 abstract description 8
- 238000000034 method Methods 0.000 abstract description 7
- 239000013543 active substance Substances 0.000 abstract 1
- 230000002708 enhancing effect Effects 0.000 abstract 1
- 239000011159 matrix material Substances 0.000 abstract 1
- 238000012986 modification Methods 0.000 abstract 1
- 230000004048 modification Effects 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 239000000203 mixture Substances 0.000 description 21
- 239000000243 solution Substances 0.000 description 13
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 description 12
- 239000003814 drug Substances 0.000 description 12
- 229940079593 drug Drugs 0.000 description 11
- 238000000338 in vitro Methods 0.000 description 8
- 239000004698 Polyethylene Substances 0.000 description 5
- 239000011162 core material Substances 0.000 description 5
- 239000000463 material Substances 0.000 description 5
- 229920000573 polyethylene Polymers 0.000 description 5
- 241000283690 Bos taurus Species 0.000 description 4
- 238000007654 immersion Methods 0.000 description 4
- -1 polyethylene Polymers 0.000 description 4
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
- 229910019142 PO4 Inorganic materials 0.000 description 3
- 239000000872 buffer Substances 0.000 description 3
- 239000010410 layer Substances 0.000 description 3
- 238000002156 mixing Methods 0.000 description 3
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 3
- 239000010452 phosphate Substances 0.000 description 3
- 239000008055 phosphate buffer solution Substances 0.000 description 3
- 239000004033 plastic Substances 0.000 description 3
- 229920003023 plastic Polymers 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- VOXZDWNPVJITMN-ZBRFXRBCSA-N 17β-estradiol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 VOXZDWNPVJITMN-ZBRFXRBCSA-N 0.000 description 2
- 238000007598 dipping method Methods 0.000 description 2
- 238000001125 extrusion Methods 0.000 description 2
- 238000010438 heat treatment Methods 0.000 description 2
- 238000001727 in vivo Methods 0.000 description 2
- 230000031700 light absorption Effects 0.000 description 2
- 238000002798 spectrophotometry method Methods 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- GGXQONWGCAQGNA-UUSVNAAPSA-N (2r,3r)-2,3-dihydroxybutanedioic acid;1-methyl-2-[(e)-2-(3-methylthiophen-2-yl)ethenyl]-5,6-dihydro-4h-pyrimidine Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O.CN1CCCN=C1\C=C\C1=C(C)C=CS1 GGXQONWGCAQGNA-UUSVNAAPSA-N 0.000 description 1
- GRRNUXAQVGOGFE-KPBUCVLVSA-N (3'r,3as,4s,4'r,5'r,6r,6'r,7s,7as)-4-[(1r,2s,3r,5s,6r)-3-amino-2,6-dihydroxy-5-(methylamino)cyclohexyl]oxy-6'-[(1s)-1-amino-2-hydroxyethyl]-6-(hydroxymethyl)spiro[4,6,7,7a-tetrahydro-3ah-[1,3]dioxolo[4,5-c]pyran-2,2'-oxane]-3',4',5',7-tetrol Chemical compound O[C@@H]1[C@@H](NC)C[C@@H](N)[C@H](O)[C@H]1O[C@H]1[C@H]2OC3([C@@H]([C@H](O)[C@@H](O)[C@@H]([C@@H](N)CO)O3)O)O[C@H]2[C@@H](O)[C@@H](CO)O1 GRRNUXAQVGOGFE-KPBUCVLVSA-N 0.000 description 1
- ZYCUDGIOGBIKAV-IPZCTEOASA-N 1-methyl-2-[(e)-2-thiophen-2-ylethenyl]-5,6-dihydro-4h-pyrimidine;hydrochloride Chemical compound Cl.CN1CCCN=C1\C=C\C1=CC=CS1 ZYCUDGIOGBIKAV-IPZCTEOASA-N 0.000 description 1
- AZSNMRSAGSSBNP-UHFFFAOYSA-N 22,23-dihydroavermectin B1a Natural products C1CC(C)C(C(C)CC)OC21OC(CC=C(C)C(OC1OC(C)C(OC3OC(C)C(O)C(OC)C3)C(OC)C1)C(C)C=CC=C1C3(C(C(=O)O4)C=C(C)C(O)C3OC1)O)CC4C2 AZSNMRSAGSSBNP-UHFFFAOYSA-N 0.000 description 1
- MVVJINIUPYKZHR-UHFFFAOYSA-N 3-[[4-[5-(methoxymethyl)-2-oxo-1,3-oxazolidin-3-yl]phenoxy]methyl]benzonitrile Chemical compound O=C1OC(COC)CN1C(C=C1)=CC=C1OCC1=CC=CC(C#N)=C1 MVVJINIUPYKZHR-UHFFFAOYSA-N 0.000 description 1
- SPBDXSGPUHCETR-JFUDTMANSA-N 8883yp2r6d Chemical compound O1[C@@H](C)[C@H](O)[C@@H](OC)C[C@@H]1O[C@@H]1[C@@H](OC)C[C@H](O[C@@H]2C(=C/C[C@@H]3C[C@@H](C[C@@]4(O[C@@H]([C@@H](C)CC4)C(C)C)O3)OC(=O)[C@@H]3C=C(C)[C@@H](O)[C@H]4OC\C([C@@]34O)=C/C=C/[C@@H]2C)/C)O[C@H]1C.C1C[C@H](C)[C@@H]([C@@H](C)CC)O[C@@]21O[C@H](C\C=C(C)\[C@@H](O[C@@H]1O[C@@H](C)[C@H](O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](OC)C3)[C@@H](OC)C1)[C@@H](C)\C=C\C=C/1[C@]3([C@H](C(=O)O4)C=C(C)[C@@H](O)[C@H]3OC\1)O)C[C@H]4C2 SPBDXSGPUHCETR-JFUDTMANSA-N 0.000 description 1
- 241000219112 Cucumis Species 0.000 description 1
- 235000015510 Cucumis melo subsp melo Nutrition 0.000 description 1
- PGNKBEARDDELNB-UHFFFAOYSA-N Diethylcarbamazine citrate Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O.CCN(CC)C(=O)N1CCN(C)CC1 PGNKBEARDDELNB-UHFFFAOYSA-N 0.000 description 1
- 206010020649 Hyperkeratosis Diseases 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 1
- 229930193140 Neomycin Natural products 0.000 description 1
- 208000031463 Palmoplantar Diffuse Keratoderma Diseases 0.000 description 1
- 208000030852 Parasitic disease Diseases 0.000 description 1
- 206010034972 Photosensitivity reaction Diseases 0.000 description 1
- KQXDHUJYNAXLNZ-XQSDOZFQSA-N Salinomycin Chemical compound O1[C@@H]([C@@H](CC)C(O)=O)CC[C@H](C)[C@@H]1[C@@H](C)[C@H](O)[C@H](C)C(=O)[C@H](CC)[C@@H]1[C@@H](C)C[C@@H](C)[C@@]2(C=C[C@@H](O)[C@@]3(O[C@@](C)(CC3)[C@@H]3O[C@@H](C)[C@@](O)(CC)CC3)O2)O1 KQXDHUJYNAXLNZ-XQSDOZFQSA-N 0.000 description 1
- 239000004189 Salinomycin Substances 0.000 description 1
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 description 1
- 239000004809 Teflon Substances 0.000 description 1
- 229920006362 Teflon® Polymers 0.000 description 1
- ZJMLMBICUVVJDX-UHFFFAOYSA-N Trifenmorph Chemical compound C1COCCN1C(C=1C=CC=CC=1)(C=1C=CC=CC=1)C1=CC=CC=C1 ZJMLMBICUVVJDX-UHFFFAOYSA-N 0.000 description 1
- XTXRWKRVRITETP-UHFFFAOYSA-N Vinyl acetate Chemical compound CC(=O)OC=C XTXRWKRVRITETP-UHFFFAOYSA-N 0.000 description 1
- FJJCIZWZNKZHII-UHFFFAOYSA-N [4,6-bis(cyanoamino)-1,3,5-triazin-2-yl]cyanamide Chemical compound N#CNC1=NC(NC#N)=NC(NC#N)=N1 FJJCIZWZNKZHII-UHFFFAOYSA-N 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 229960000723 ampicillin Drugs 0.000 description 1
- AVKUERGKIZMTKX-NJBDSQKTSA-N ampicillin Chemical compound C1([C@@H](N)C(=O)N[C@H]2[C@H]3SC([C@@H](N3C2=O)C(O)=O)(C)C)=CC=CC=C1 AVKUERGKIZMTKX-NJBDSQKTSA-N 0.000 description 1
- KLOHDWPABZXLGI-YWUHCJSESA-M ampicillin sodium Chemical compound [Na+].C1([C@@H](N)C(=O)N[C@H]2[C@H]3SC([C@@H](N3C2=O)C([O-])=O)(C)C)=CC=CC=C1 KLOHDWPABZXLGI-YWUHCJSESA-M 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 239000003054 catalyst Substances 0.000 description 1
- 239000004568 cement Substances 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 229920001577 copolymer Polymers 0.000 description 1
- 229960004837 diethylcarbamazine citrate Drugs 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 229920001971 elastomer Polymers 0.000 description 1
- 239000000806 elastomer Substances 0.000 description 1
- 229960005309 estradiol Drugs 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 239000003292 glue Substances 0.000 description 1
- 238000000227 grinding Methods 0.000 description 1
- 238000004128 high performance liquid chromatography Methods 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 230000003834 intracellular effect Effects 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 229960002418 ivermectin Drugs 0.000 description 1
- 239000008101 lactose Substances 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 230000005923 long-lasting effect Effects 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 229960003546 morantel tartrate Drugs 0.000 description 1
- 229960004927 neomycin Drugs 0.000 description 1
- 201000006079 nonepidermolytic palmoplantar keratoderma Diseases 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 230000036211 photosensitivity Effects 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 239000013615 primer Substances 0.000 description 1
- 239000002987 primer (paints) Substances 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 238000004080 punching Methods 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 210000000090 ruminant stomach Anatomy 0.000 description 1
- 229960001548 salinomycin Drugs 0.000 description 1
- 235000019378 salinomycin Nutrition 0.000 description 1
- 231100000241 scar Toxicity 0.000 description 1
- 239000004460 silage Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 235000019333 sodium laurylsulphate Nutrition 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- KSBAEPSJVUENNK-UHFFFAOYSA-L tin(ii) 2-ethylhexanoate Chemical compound [Sn+2].CCCCC(CC)C([O-])=O.CCCCC(CC)C([O-])=O KSBAEPSJVUENNK-UHFFFAOYSA-L 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
- CPYIZQLXMGRKSW-UHFFFAOYSA-N zinc;iron(3+);oxygen(2-) Chemical compound [O-2].[O-2].[O-2].[O-2].[Fe+3].[Fe+3].[Zn+2] CPYIZQLXMGRKSW-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
- A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Anesthesiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- Medicinal Preparation (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Laminated Bodies (AREA)
- Paper (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Lubricants (AREA)
- Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
- Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
- Processing And Handling Of Plastics And Other Materials For Molding In General (AREA)
- Liquid Developers In Electrophotography (AREA)
- Control Of Steam Boilers And Waste-Gas Boilers (AREA)
- Separation By Low-Temperature Treatments (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
- Mattresses And Other Support Structures For Chairs And Beds (AREA)
- Bedding Items (AREA)
- Fodder In General (AREA)
- Feed For Specific Animals (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| LV931166A LV5396A3 (lv) | 1984-02-08 | 1993-10-22 | Ierice ilgstosai arstnieciskas vielas ievadisanai atgremotajdzivnieku kunga spurekli |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US57795084A | 1984-02-08 | 1984-02-08 | |
| CN85102106A CN85102106B (zh) | 1984-02-08 | 1985-04-01 | 一种控制和延长物质向周围环境物释放的叠层装置之生产方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SU1602389A3 true SU1602389A3 (ru) | 1990-10-23 |
Family
ID=25741540
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SU853853845A SU1602389A3 (ru) | 1984-02-08 | 1985-02-05 | Устройство дл длительного высвобождени лекарственного вещества в рубцово-сетчатом отделе желудка жвачных животных |
Country Status (30)
| Country | Link |
|---|---|
| EP (1) | EP0153070B1 (enExample) |
| JP (1) | JPS60190709A (enExample) |
| KR (1) | KR880000431B1 (enExample) |
| CN (1) | CN85102106B (enExample) |
| AT (1) | ATE63219T1 (enExample) |
| AU (1) | AU548349B2 (enExample) |
| BR (1) | BR8500551A (enExample) |
| CA (1) | CA1237982A (enExample) |
| DD (1) | DD231984A5 (enExample) |
| DE (1) | DE3582738D1 (enExample) |
| DK (1) | DK164476C (enExample) |
| EG (1) | EG16774A (enExample) |
| ES (2) | ES8605672A1 (enExample) |
| FI (1) | FI85326C (enExample) |
| GR (1) | GR850334B (enExample) |
| HU (1) | HU201241B (enExample) |
| IE (1) | IE57740B1 (enExample) |
| IL (1) | IL74263A (enExample) |
| IN (1) | IN162525B (enExample) |
| MX (1) | MX163557B (enExample) |
| NO (1) | NO171146C (enExample) |
| NZ (1) | NZ211053A (enExample) |
| PH (1) | PH21485A (enExample) |
| PL (1) | PL150560B1 (enExample) |
| PT (1) | PT79929B (enExample) |
| SU (1) | SU1602389A3 (enExample) |
| UA (1) | UA6341A1 (enExample) |
| YU (1) | YU45231B (enExample) |
| ZA (1) | ZA85933B (enExample) |
| ZW (1) | ZW1785A1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2116064C1 (ru) * | 1996-12-30 | 1998-07-27 | Закрытое акционерное общество "Пульмомед" | Способ получения лекарственной формы с регулируемым выделением лекарственного препарата |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4661388A (en) * | 1985-01-24 | 1987-04-28 | Minnesota Mining And Manufacturing Company | Pad fragrance sampling device |
| US4663147A (en) * | 1985-09-03 | 1987-05-05 | International Minerals & Chemical Corp. | Disc-like sustained release formulation |
| US4735738A (en) * | 1985-10-21 | 1988-04-05 | The Procter & Gamble Company | Article with laminated paper orientation for improved fabric softening |
| US4816262A (en) * | 1986-08-28 | 1989-03-28 | Universite De Montreal | Controlled release tablet |
| US4830860A (en) * | 1986-10-30 | 1989-05-16 | Pfizer Inc. | Stressed polymeric device for controlled release of a substance to an ambient environment |
| US4792448A (en) * | 1987-06-11 | 1988-12-20 | Pfizer Inc. | Generic zero order controlled drug delivery system |
| US4861596A (en) * | 1988-03-21 | 1989-08-29 | Pfizer Inc. | Rolled matrix device having enhanced ability to unroll and method for its production |
| EP0334516A3 (en) * | 1988-03-21 | 1991-07-03 | Pfizer Inc. | Method for enhancing the unrolling of a rolled matrix device |
| GB8815968D0 (en) * | 1988-07-05 | 1988-08-10 | Pfizer Ltd | Veterinary devices |
| GB8820242D0 (en) * | 1988-08-25 | 1988-09-28 | Kent B E | Sustained release device |
| FR2658827B1 (fr) * | 1990-02-27 | 1993-12-17 | Rhone Poulenc Agrochimie | Compositions solides silicones a action biologique agricoles. |
| AUPQ573300A0 (en) * | 2000-02-21 | 2000-03-16 | Australian Nuclear Science & Technology Organisation | Controlled release ceramic particles, compositions thereof, processes of preparation and methods of use |
| US8298574B2 (en) | 2006-01-18 | 2012-10-30 | Intec Pharma Ltd. | Method and apparatus for forming delivery devices for oral intake of an agent |
| SG138567A1 (en) * | 2006-06-21 | 2008-01-28 | Johnson & Johnson Vision Care | Punctal plugs for the delivery of active agents |
| WO2013102034A1 (en) | 2011-12-30 | 2013-07-04 | Kibur Medical, Inc. | Implantable devices and methods for the evaluation of active agent |
| JP6348330B2 (ja) * | 2014-04-22 | 2018-06-27 | 株式会社テックコーポレーション | 水素放出器、水素ガス供給方法及び水素放出システム |
| CN106237338A (zh) * | 2016-09-05 | 2016-12-21 | 四川大学 | 一种制备层状生物降解高分子药物控释材料的方法 |
| CN115038331B (zh) * | 2019-12-06 | 2024-03-19 | S.C.约翰逊父子公司 | 散发器及其使用方法 |
| CN113502546B (zh) * | 2021-07-06 | 2022-08-19 | 中国电子科技集团公司第十三研究所 | 一种磁场下合成及连续生长磷化物的方法 |
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| US3113076A (en) * | 1956-07-03 | 1963-12-03 | Henry R Jacobs | Medicinal tablets |
| AU454482B2 (en) * | 1970-11-05 | 1974-10-15 | Alza Corporation | Drug-delivery system |
| DK156375C (da) * | 1978-11-07 | 1990-03-05 | Pfizer | Praeparater til oral administration til droevtyggere med langvarig medikamentafgivelse |
| EP0021758B1 (en) * | 1979-06-27 | 1984-04-04 | Beecham Group Plc | Veterinary preparations for ruminant animals |
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1984
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1985
- 1985-02-04 AT AT85300723T patent/ATE63219T1/de not_active IP Right Cessation
- 1985-02-04 DE DE8585300723T patent/DE3582738D1/de not_active Expired - Lifetime
- 1985-02-04 EP EP85300723A patent/EP0153070B1/en not_active Expired - Lifetime
- 1985-02-05 NZ NZ211053A patent/NZ211053A/en unknown
- 1985-02-05 UA UA3853845A patent/UA6341A1/uk unknown
- 1985-02-05 ES ES540130A patent/ES8605672A1/es not_active Expired
- 1985-02-05 SU SU853853845A patent/SU1602389A3/ru active
- 1985-02-06 GR GR850334A patent/GR850334B/el not_active IP Right Cessation
- 1985-02-06 EG EG72/85A patent/EG16774A/xx active
- 1985-02-06 PT PT79929A patent/PT79929B/pt unknown
- 1985-02-06 CA CA000473649A patent/CA1237982A/en not_active Expired
- 1985-02-06 IL IL74263A patent/IL74263A/xx not_active IP Right Cessation
- 1985-02-07 PH PH31829A patent/PH21485A/en unknown
- 1985-02-07 NO NO850469A patent/NO171146C/no not_active IP Right Cessation
- 1985-02-07 MX MX204262A patent/MX163557B/es unknown
- 1985-02-07 YU YU188/85A patent/YU45231B/xx unknown
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- 1985-02-07 KR KR1019850000775A patent/KR880000431B1/ko not_active Expired
- 1985-02-07 PL PL1985251907A patent/PL150560B1/pl unknown
- 1985-02-07 AU AU38525/85A patent/AU548349B2/en not_active Expired
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- 1985-02-08 JP JP60023387A patent/JPS60190709A/ja active Granted
- 1985-04-01 CN CN85102106A patent/CN85102106B/zh not_active Expired
- 1985-12-16 ES ES1985291052U patent/ES291052Y/es not_active Expired
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2116064C1 (ru) * | 1996-12-30 | 1998-07-27 | Закрытое акционерное общество "Пульмомед" | Способ получения лекарственной формы с регулируемым выделением лекарственного препарата |
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