KR850005940A - 활성약품의 장기간 조절방출용 기구의 제조방법 - Google Patents

활성약품의 장기간 조절방출용 기구의 제조방법 Download PDF

Info

Publication number
KR850005940A
KR850005940A KR1019850000775A KR850000775A KR850005940A KR 850005940 A KR850005940 A KR 850005940A KR 1019850000775 A KR1019850000775 A KR 1019850000775A KR 850000775 A KR850000775 A KR 850000775A KR 850005940 A KR850005940 A KR 850005940A
Authority
KR
South Korea
Prior art keywords
mentioned
drug
core sheet
environment
polymer matrix
Prior art date
Application number
KR1019850000775A
Other languages
English (en)
Other versions
KR880000431B1 (ko
Inventor
로버트 카디날 죤
Original Assignee
윌리암 데이비스 훈
화이자 인코포레이티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 윌리암 데이비스 훈, 화이자 인코포레이티드 filed Critical 윌리암 데이비스 훈
Publication of KR850005940A publication Critical patent/KR850005940A/ko
Application granted granted Critical
Publication of KR880000431B1 publication Critical patent/KR880000431B1/ko

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Anesthesiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Laminated Bodies (AREA)
  • Paper (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Lubricants (AREA)
  • Liquid Developers In Electrophotography (AREA)
  • Separation By Low-Temperature Treatments (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
  • Control Of Steam Boilers And Waste-Gas Boilers (AREA)
  • Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Processing And Handling Of Plastics And Other Materials For Molding In General (AREA)
  • Bedding Items (AREA)
  • Mattresses And Other Support Structures For Chairs And Beds (AREA)
  • Fodder In General (AREA)
  • Feed For Specific Animals (AREA)

Abstract

내용 없음

Description

활성약품의 장기간 조절방출용 기구의 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제1도는 가장자리가 노출되어 있는 본 발명의 3층(샌드위치)적층물기구의 5의 투시도이고,
제2도는 가장자리가 피복되어 있는 본 발명의 적층물기구 5의 투시도이고 전개부는 활성약품을 담지하고 있는 코오쉬트를 도시한 것이며,
제3도는 한정된 형상의 제2도기구를 도시한 것이고.

Claims (11)

1종이상의 활성약품과 중합체 매트릭스로 이루어진 1개이상의 코어쉬트를 주위환경 및 사용된 약품에 대해 거의 불투과성인 공연신 중합체 필름사이에 적층시키고, 언급된 필름과 코어쉬트를 관통하여 1개이상의 거시구멍(여기서, 코어쉬트의 두께와 관련된 거시구멍의 직경과 배열은, 쉬트의 충분한 내부 가장자리 면적이 주위환경에 노출되어 사용된 약품의 바람직한 방출속도를 수득할 수 있도록 선택된다)을 천공시킴을 특징으로 하는, 1종 이상의 활성약품의 주위환경으로의 장기간 조절방출을 위한 기구의 제조방법.
제1항에 있어서, 언급된 거시구멍을 기구표면상에 대칭적으로 분포시키며, 언급된 코어쉬트가 중합체 매트릭스중의 활성약품의 균질혼합물로 이루어지는 방법.
제1항에 있어서, 언급된 거시구멍이 직경 약 0.5내지 10mm의 원형인 방법.
제1항 내지 제3항중 어느 하나에 있어서, 언급된 코어쉬트의 외곽 가장자리를 주위환경과 사용된 약품에 대해 거의 불투과성인 필름으로 피복시키는 방법.
제1항에 있어서, 언급된 약품을 코어쉬트중에 분산 또는 용해시키며, 약품을 코어쉬트의 약 0.1내지 약 0.75중량%의 농도로 존재시키는 방법.
제1항 내지 제5항중 어느 하나에 있어서, 언급된 코어쉬트가 1종이상의 활성약품, 주위환경중에서 유한한 용해도를갖는 분산된 포로시겐, 및 중합체 매트릭스로 이루어지는 방법.
제1항 내지 6항중 어느 하나에 있어서, 언급된 약품이 약제인 방법.
제7항에 있어서, 언급된 약품이 구충제인 방법.
제8항에 있어서, 언급된 약품이 모란텔, 피란텔 또는 레바미졸의 수용성 산부가염인 방법.
제9항에 있어서, 언급된 악품이 모란텔 시트레이트 또는 모란텔 타르트레이트인 방법.
제1내지 제10항중 어느 하나에 있어서,언급된 코어쉬트와 공연신 중합체 필름이 에틸렌비닐아세테이트 공중합체로 이루어지는 방법.
※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019850000775A 1984-02-08 1985-02-07 활성약품의 장기간 조절방출용 기구 KR880000431B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US57795084A 1984-02-08 1984-02-08
US577,950 1984-02-08
CN85102106A CN85102106B (zh) 1984-02-08 1985-04-01 一种控制和延长物质向周围环境物释放的叠层装置之生产方法

Publications (2)

Publication Number Publication Date
KR850005940A true KR850005940A (ko) 1985-09-28
KR880000431B1 KR880000431B1 (ko) 1988-03-24

Family

ID=25741540

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019850000775A KR880000431B1 (ko) 1984-02-08 1985-02-07 활성약품의 장기간 조절방출용 기구

Country Status (30)

Country Link
EP (1) EP0153070B1 (ko)
JP (1) JPS60190709A (ko)
KR (1) KR880000431B1 (ko)
CN (1) CN85102106B (ko)
AT (1) ATE63219T1 (ko)
AU (1) AU548349B2 (ko)
BR (1) BR8500551A (ko)
CA (1) CA1237982A (ko)
DD (1) DD231984A5 (ko)
DE (1) DE3582738D1 (ko)
DK (1) DK164476C (ko)
EG (1) EG16774A (ko)
ES (2) ES8605672A1 (ko)
FI (1) FI85326C (ko)
GR (1) GR850334B (ko)
HU (1) HU201241B (ko)
IE (1) IE57740B1 (ko)
IL (1) IL74263A (ko)
IN (1) IN162525B (ko)
MX (1) MX163557B (ko)
NO (1) NO171146C (ko)
NZ (1) NZ211053A (ko)
PH (1) PH21485A (ko)
PL (1) PL150560B1 (ko)
PT (1) PT79929B (ko)
SU (1) SU1602389A3 (ko)
UA (1) UA6341A1 (ko)
YU (1) YU45231B (ko)
ZA (1) ZA85933B (ko)
ZW (1) ZW1785A1 (ko)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4661388A (en) * 1985-01-24 1987-04-28 Minnesota Mining And Manufacturing Company Pad fragrance sampling device
US4663147A (en) * 1985-09-03 1987-05-05 International Minerals & Chemical Corp. Disc-like sustained release formulation
US4735738A (en) * 1985-10-21 1988-04-05 The Procter & Gamble Company Article with laminated paper orientation for improved fabric softening
US4816262A (en) * 1986-08-28 1989-03-28 Universite De Montreal Controlled release tablet
US4830860A (en) * 1986-10-30 1989-05-16 Pfizer Inc. Stressed polymeric device for controlled release of a substance to an ambient environment
US4792448A (en) * 1987-06-11 1988-12-20 Pfizer Inc. Generic zero order controlled drug delivery system
EP0334516A3 (en) * 1988-03-21 1991-07-03 Pfizer Inc. Method for enhancing the unrolling of a rolled matrix device
US4861596A (en) * 1988-03-21 1989-08-29 Pfizer Inc. Rolled matrix device having enhanced ability to unroll and method for its production
GB8815968D0 (en) * 1988-07-05 1988-08-10 Pfizer Ltd Veterinary devices
GB8820242D0 (en) * 1988-08-25 1988-09-28 Kent B E Sustained release device
FR2658827B1 (fr) * 1990-02-27 1993-12-17 Rhone Poulenc Agrochimie Compositions solides silicones a action biologique agricoles.
AUPQ573300A0 (en) * 2000-02-21 2000-03-16 Australian Nuclear Science & Technology Organisation Controlled release ceramic particles, compositions thereof, processes of preparation and methods of use
ES2559678T3 (es) 2006-01-18 2016-02-15 Intec Pharma Ltd. Método para formar dispositivos de suministro para la vía oral de un agente
SG138567A1 (en) * 2006-06-21 2008-01-28 Johnson & Johnson Vision Care Punctal plugs for the delivery of active agents
WO2013102034A1 (en) * 2011-12-30 2013-07-04 Kibur Medical, Inc. Implantable devices and methods for the evaluation of active agent
JP6348330B2 (ja) * 2014-04-22 2018-06-27 株式会社テックコーポレーション 水素放出器、水素ガス供給方法及び水素放出システム
CN106237338A (zh) * 2016-09-05 2016-12-21 四川大学 一种制备层状生物降解高分子药物控释材料的方法
BR112022010950A2 (pt) * 2019-12-06 2022-09-06 Johnson & Son Inc S C Dispensador e método de uso do mesmo
CN113502546B (zh) * 2021-07-06 2022-08-19 中国电子科技集团公司第十三研究所 一种磁场下合成及连续生长磷化物的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3113076A (en) * 1956-07-03 1963-12-03 Henry R Jacobs Medicinal tablets
AU454482B2 (en) * 1970-11-05 1974-10-15 Alza Corporation Drug-delivery system
DE2966275D1 (en) * 1978-11-07 1983-11-10 Beecham Group Plc Device for oral administration to a ruminant animal
DE3067332D1 (en) * 1979-06-27 1984-05-10 Beecham Group Plc Veterinary preparations for ruminant animals

Also Published As

Publication number Publication date
NO850469L (no) 1985-08-09
FI85326B (fi) 1991-12-31
NZ211053A (en) 1987-06-30
ATE63219T1 (de) 1991-05-15
IN162525B (ko) 1988-06-04
PT79929A (en) 1985-03-01
DK164476C (da) 1992-11-16
CN85102106A (zh) 1987-01-31
FI85326C (fi) 1992-04-10
ZA85933B (en) 1986-09-24
PH21485A (en) 1987-11-10
DK164476B (da) 1992-07-06
UA6341A1 (uk) 1994-12-29
AU548349B2 (en) 1985-12-05
IE57740B1 (en) 1993-03-24
NO171146C (no) 1993-02-03
ES291052U (es) 1986-04-16
HU201241B (en) 1990-10-28
EG16774A (en) 1991-11-30
MX163557B (es) 1992-05-29
DK55385A (da) 1985-09-19
DD231984A5 (de) 1986-01-15
FI850518A0 (fi) 1985-02-07
ES540130A0 (es) 1986-04-01
ES291052Y (es) 1986-12-01
HUT41257A (en) 1987-04-28
DK55385D0 (da) 1985-02-07
DE3582738D1 (de) 1991-06-13
JPS60190709A (ja) 1985-09-28
EP0153070A3 (en) 1987-07-15
CN85102106B (zh) 1988-09-14
PL251907A1 (en) 1987-11-02
KR880000431B1 (ko) 1988-03-24
ZW1785A1 (en) 1985-05-08
IE850299L (en) 1985-08-08
CA1237982A (en) 1988-06-14
FI850518L (fi) 1985-08-09
PL150560B1 (en) 1990-06-30
ES8605672A1 (es) 1986-04-01
PT79929B (en) 1987-02-02
EP0153070A2 (en) 1985-08-28
IL74263A0 (en) 1985-05-31
BR8500551A (pt) 1985-09-24
IL74263A (en) 1990-08-31
AU3852585A (en) 1985-08-15
GR850334B (ko) 1985-06-06
YU18885A (en) 1988-02-29
SU1602389A3 (ru) 1990-10-23
EP0153070B1 (en) 1991-05-08
NO171146B (no) 1992-10-26
JPH0442365B2 (ko) 1992-07-13
YU45231B (en) 1992-05-28

Similar Documents

Publication Publication Date Title
KR850005940A (ko) 활성약품의 장기간 조절방출용 기구의 제조방법
DK566587D0 (da) Matrixindretning til styret afgivelse af mindst et aktivt middel til et omgivende miljoe og fremgangsmaader til fremstilling og anvendelse deraf
DE3687622T2 (de) Koextrudierter sauerstoffsperrfilm.
JPS57104133A (en) Silver halide photographic material
JPS56110613A (en) Fomentation
JPS57136513A (en) Material for controlling release of physiologically active substance
JPS53128582A (en) Method of fabricating semipermeable membrane

Legal Events

Date Code Title Description
A201 Request for examination
E902 Notification of reason for refusal
G160 Decision to publish patent application
E701 Decision to grant or registration of patent right
GRNT Written decision to grant
FPAY Annual fee payment

Payment date: 20040113

Year of fee payment: 17

EXPY Expiration of term