SU1287753A3 - Способ получени производных 6-амино-7-окси-4,5,6,7-тетрагидроимидазо-/4,5,1- @ - @ /-/1/-бензазепин-2/1 @ /-она или их кислотно-аддитивных солей - Google Patents

Способ получени производных 6-амино-7-окси-4,5,6,7-тетрагидроимидазо-/4,5,1- @ - @ /-/1/-бензазепин-2/1 @ /-она или их кислотно-аддитивных солей Download PDF

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Publication number
SU1287753A3
SU1287753A3 SU833654552A SU3654552A SU1287753A3 SU 1287753 A3 SU1287753 A3 SU 1287753A3 SU 833654552 A SU833654552 A SU 833654552A SU 3654552 A SU3654552 A SU 3654552A SU 1287753 A3 SU1287753 A3 SU 1287753A3
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SU
USSR - Soviet Union
Prior art keywords
acid
amino
benzazepin
general formula
compound
Prior art date
Application number
SU833654552A
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English (en)
Russian (ru)
Inventor
Фреше Даниель
Неделек Люсьен
Плассар Ги
Лесли Браун Неил
Original Assignee
Руссель-Юклаф (Фирма)
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Publication of SU1287753A3 publication Critical patent/SU1287753A3/ru

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SU833654552A 1982-10-12 1983-10-11 Способ получени производных 6-амино-7-окси-4,5,6,7-тетрагидроимидазо-/4,5,1- @ - @ /-/1/-бензазепин-2/1 @ /-она или их кислотно-аддитивных солей SU1287753A3 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8217054A FR2534257A1 (fr) 1982-10-12 1982-10-12 Nouveaux derives de la 6-amino 7-hydroxy 4,5,6,7-tetrahydro-imidazo/4,5,1-j-k/ /1/ benzazepin-2(1h)-one, leurs sels, application a titre de medicaments, compositions les renfermant et un intermediaire

Publications (1)

Publication Number Publication Date
SU1287753A3 true SU1287753A3 (ru) 1987-01-30

Family

ID=9278183

Family Applications (2)

Application Number Title Priority Date Filing Date
SU833654552A SU1287753A3 (ru) 1982-10-12 1983-10-11 Способ получени производных 6-амино-7-окси-4,5,6,7-тетрагидроимидазо-/4,5,1- @ - @ /-/1/-бензазепин-2/1 @ /-она или их кислотно-аддитивных солей
SU864015498A SU1384201A3 (ru) 1982-10-12 1986-01-30 Способ получени 4,5-дигидроимидазо- @ 4,5,1-J-к @ /1/-бензазепин-2,7-/1Н,6Н/-диона

Family Applications After (1)

Application Number Title Priority Date Filing Date
SU864015498A SU1384201A3 (ru) 1982-10-12 1986-01-30 Способ получени 4,5-дигидроимидазо- @ 4,5,1-J-к @ /1/-бензазепин-2,7-/1Н,6Н/-диона

Country Status (23)

Country Link
US (1) US4585770A (https=)
EP (1) EP0107569B1 (https=)
JP (1) JPS59130289A (https=)
KR (1) KR900006753B1 (https=)
AT (1) ATE25981T1 (https=)
AU (1) AU559422B2 (https=)
CA (2) CA1216847A (https=)
DD (1) DD215784A5 (https=)
DE (1) DE3370332D1 (https=)
DK (1) DK163734C (https=)
ES (1) ES8405802A1 (https=)
FI (1) FI76340C (https=)
FR (1) FR2534257A1 (https=)
GR (1) GR78731B (https=)
HU (1) HU188499B (https=)
IE (1) IE59441B1 (https=)
IL (1) IL69993A (https=)
MX (1) MX8495A (https=)
NZ (1) NZ205918A (https=)
PH (1) PH20031A (https=)
PT (1) PT77469B (https=)
SU (2) SU1287753A3 (https=)
ZA (1) ZA837480B (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2133249C1 (ru) * 1993-07-13 1999-07-20 Жансен Фармасетика Н.В. Производное имидазоазепина, фармацевтическая композиция, способ ее получения и способы получения производного имидазоазепина
RU2433131C2 (ru) * 2007-02-01 2011-11-10 Интервет Интернэшнл Б.В. ЭНАНТИОСЕЛЕКТИВНЫЙ СИНТЕЗ 6-АМИНО-7-ГИДРОКСИ-4,5,6,7-ТЕТРАГИДРОИМИДАЗО[4,5,1-jk][1]БЕНЗАЗЕПИН-2[1H]-ОНА И ЗИЛПАТЕРОЛА

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU616390B2 (en) * 1986-12-11 1991-10-31 Hoechst Roussel Vet S.A. Zootechnical compositions containing a beta-adrenergic
FR2608046B1 (fr) * 1986-12-11 1989-03-31 Roussel Uclaf Compositions zootechniques renfermant un derive de la 6-amino 7-hydroxy 4,5,6,7-tetrahydroimidazo /4,5, 1-j-k/ /1/benzazepin-2-(1h)-one
IE60964B1 (en) * 1986-12-11 1994-09-07 Roussel Uclaf Zootechnical compositions containing a beta-adrenergic
FR2608047B1 (fr) * 1986-12-11 1990-08-31 Roussel Uclaf Compositions zootechniques renfermant un derive de la 6-amino 7-hydroxy 4,5,6,7-tetrahydroimidazo /4,5,1-j-k/ /1/ benzazepin-2-(1h)-one
GB8806449D0 (en) * 1988-03-18 1988-04-20 Janssen Pharmaceutica Nv Antiviral hexahydroimiazo(1 4)benzodiazepin-2-ones
IL93136A (en) * 1989-02-23 1995-01-24 Janssen Pharmaceutica Nv Tetrahydroimidazo (1,4) benzodiazepin-2-thione derivatives, their preparation and pharmaceutical compositions containing them
FR2735474B1 (fr) * 1995-06-13 1997-08-08 Roussel Uclaf Chlorhydrate de zilpaterol sous une forme cristallisee particuliere, son procede de preparation et les produits intermediaires mis en oeuvre
US7207289B2 (en) * 2004-05-20 2007-04-24 Intervet International B.V. Method of feeding the cattle with feed additives that increases beef production and reduces liver abscess
BRPI0719187A2 (pt) * 2006-10-13 2014-09-09 Pfizer Ltd Composto heterocíclicos úteis como agentes anábolicos para animais de criação
WO2008050207A1 (en) * 2006-10-25 2008-05-02 Pfizer Limited Heterocyclic compounds useful as anabolic agents for livestock animals
JP5856990B2 (ja) * 2007-03-31 2016-02-10 インターベット インターナショナル ベー． フェー． ジルパテロールおよびこの塩の製造方法
BRPI0809493B1 (pt) 2007-03-31 2016-11-08 Intervet Int Bv processo para preparar zilpaterol ou um sal deste
MX2009010499A (es) * 2007-03-31 2009-10-19 Intervet Int Bv Procesos para elaborar zilpaterol y sales del mismo.
RU2442786C2 (ru) * 2007-03-31 2012-02-20 Интервет Интернэшнл Б.В. Способы получения зилпатерола и его солей
EP1995248A1 (en) * 2007-05-23 2008-11-26 Evonik Degussa GmbH Process for the production of amino alcohols by asymmetric hydrogenation
BRPI0820591A2 (pt) 2007-12-06 2015-06-16 Intervet Int Bv Método para melhorar eficiência de utilização de ração ou aumentar a taxa de ganho de peso em um animal, composição, ração de ruminante, e kit para administrar zilpaterol (ou um sal do mesmo) e acetato de melengestrol a um animal.
TW201033217A (en) * 2008-12-17 2010-09-16 Intervet Int Bv Process for making a crystalline zilpaterol salt
WO2013171330A1 (en) 2012-05-18 2013-11-21 Intervet International B.V. A method of enhancing performance in broiler chickens
CA2895153C (en) * 2012-12-18 2021-02-02 Intervet International B.V. An improved process for making zilpaterol
US20160022694A1 (en) 2013-03-15 2016-01-28 Intervet Inc. A Method of Improving the Efficiency of Beef Production from Bovine Animals
CN104418808A (zh) * 2013-09-11 2015-03-18 中美华世通生物医药科技（武汉）有限公司 一种适于工业化生产的中间体Buzolic acid的制备方法
CN103554113B (zh) * 2013-09-25 2016-04-27 湖北美天生物科技有限公司 一种盐酸齐帕特罗的合成方法
RU2018105703A (ru) 2015-07-21 2019-08-22 Интервет Интернэшнл Б.В. Новый состав премикса для животных на основе зилпатерола
EP3488705A1 (en) 2017-11-23 2019-05-29 Saviela AG Solubilized growth promoting product to be applied orally to animals and method for the respective feed preparation
CN108752352B (zh) * 2018-04-18 2019-11-26 江苏凌云药业股份有限公司 一种盐酸齐帕特罗的合成方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2320439A (en) * 1943-06-01 Bottle carrier
US3200123A (en) * 1962-01-26 1965-08-10 Richardson Merreil Inc Imidazoquinolines
EP0034989B1 (fr) * 1980-02-26 1983-10-05 Roussel-Uclaf Nouveaux dérivés du cycloheptindolol et leurs sels avec les acides, leur préparation, leur application comme médicaments et les compositions les renfermant

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Патент FR № 1363948, кл. А 61 К, 1964. *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2133249C1 (ru) * 1993-07-13 1999-07-20 Жансен Фармасетика Н.В. Производное имидазоазепина, фармацевтическая композиция, способ ее получения и способы получения производного имидазоазепина
RU2433131C2 (ru) * 2007-02-01 2011-11-10 Интервет Интернэшнл Б.В. ЭНАНТИОСЕЛЕКТИВНЫЙ СИНТЕЗ 6-АМИНО-7-ГИДРОКСИ-4,5,6,7-ТЕТРАГИДРОИМИДАЗО[4,5,1-jk][1]БЕНЗАЗЕПИН-2[1H]-ОНА И ЗИЛПАТЕРОЛА

Also Published As

Publication number Publication date
ATE25981T1 (de) 1987-04-15
ES526390A0 (es) 1984-06-16
DD215784A5 (de) 1984-11-21
IE832387L (en) 1984-04-12
NZ205918A (en) 1985-12-13
EP0107569B1 (fr) 1987-03-18
FR2534257B1 (https=) 1984-12-28
PT77469A (fr) 1983-11-01
FI833697L (fi) 1984-04-13
PT77469B (fr) 1986-05-07
AU559422B2 (en) 1987-03-12
CA1222246A (fr) 1987-05-26
FI76340B (fi) 1988-06-30
DK163734C (da) 1992-08-31
DK163734B (da) 1992-03-30
SU1384201A3 (ru) 1988-03-23
GR78731B (https=) 1984-10-02
DK466483D0 (da) 1983-10-11
JPS59130289A (ja) 1984-07-26
IL69993A0 (en) 1984-01-31
ZA837480B (en) 1984-11-28
US4585770A (en) 1986-04-29
FI833697A0 (fi) 1983-10-11
MX8495A (es) 1993-09-01
DK466483A (da) 1984-04-13
DE3370332D1 (en) 1987-04-23
KR900006753B1 (ko) 1990-09-20
IE59441B1 (en) 1994-02-23
ES8405802A1 (es) 1984-06-16
FR2534257A1 (fr) 1984-04-13
CA1216847A (fr) 1987-01-20
FI76340C (fi) 1988-10-10
IL69993A (en) 1987-10-30
EP0107569A1 (fr) 1984-05-02
HU188499B (en) 1986-04-28
AU2005383A (en) 1984-04-19
PH20031A (en) 1986-09-04
JPH0454671B2 (https=) 1992-08-31
KR840006484A (ko) 1984-11-30

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