DK466483A - Fremgangsmaade til fremstilling af 6-amino-7-hydroxy-4,5,6,7-tetrahydroimidazo(4,5,1-j-k)-1-benzazepin-2-1h-onderivater og deres salte - Google Patents

Fremgangsmaade til fremstilling af 6-amino-7-hydroxy-4,5,6,7-tetrahydroimidazo(4,5,1-j-k)-1-benzazepin-2-1h-onderivater og deres salte Download PDF

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Publication number
DK466483A
DK466483A DK466483A DK466483A DK466483A DK 466483 A DK466483 A DK 466483A DK 466483 A DK466483 A DK 466483A DK 466483 A DK466483 A DK 466483A DK 466483 A DK466483 A DK 466483A
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DK
Denmark
Prior art keywords
amino
carbon atoms
hydroxy
salts
undiverivatives
Prior art date
Application number
DK466483A
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English (en)
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DK466483D0 (da
DK163734B (da
DK163734C (da
Inventor
Daniel Frechet
Lucien Nedelec
Guy Plassard
Neil Leslie Brown
Original Assignee
Roussel Uclaf
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Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of DK466483D0 publication Critical patent/DK466483D0/da
Publication of DK466483A publication Critical patent/DK466483A/da
Publication of DK163734B publication Critical patent/DK163734B/da
Application granted granted Critical
Publication of DK163734C publication Critical patent/DK163734C/da

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK466483A 1982-10-12 1983-10-11 Fremgangsmaade til fremstilling af 6-amino-7-hydroxy-4,5,6,7-tetrahydroimidazo(4,5,1-j-k)-1-benzazepin-2-1h-onderivater og deres salte DK163734C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8217054 1982-10-12
FR8217054A FR2534257A1 (fr) 1982-10-12 1982-10-12 Nouveaux derives de la 6-amino 7-hydroxy 4,5,6,7-tetrahydro-imidazo/4,5,1-j-k/ /1/ benzazepin-2(1h)-one, leurs sels, application a titre de medicaments, compositions les renfermant et un intermediaire

Publications (4)

Publication Number Publication Date
DK466483D0 DK466483D0 (da) 1983-10-11
DK466483A true DK466483A (da) 1984-04-13
DK163734B DK163734B (da) 1992-03-30
DK163734C DK163734C (da) 1992-08-31

Family

ID=9278183

Family Applications (1)

Application Number Title Priority Date Filing Date
DK466483A DK163734C (da) 1982-10-12 1983-10-11 Fremgangsmaade til fremstilling af 6-amino-7-hydroxy-4,5,6,7-tetrahydroimidazo(4,5,1-j-k)-1-benzazepin-2-1h-onderivater og deres salte

Country Status (23)

Country Link
US (1) US4585770A (da)
EP (1) EP0107569B1 (da)
JP (1) JPS59130289A (da)
KR (1) KR900006753B1 (da)
AT (1) ATE25981T1 (da)
AU (1) AU559422B2 (da)
CA (2) CA1216847A (da)
DD (1) DD215784A5 (da)
DE (1) DE3370332D1 (da)
DK (1) DK163734C (da)
ES (1) ES8405802A1 (da)
FI (1) FI76340C (da)
FR (1) FR2534257A1 (da)
GR (1) GR78731B (da)
HU (1) HU188499B (da)
IE (1) IE59441B1 (da)
IL (1) IL69993A (da)
MX (1) MX8495A (da)
NZ (1) NZ205918A (da)
PH (1) PH20031A (da)
PT (1) PT77469B (da)
SU (2) SU1287753A3 (da)
ZA (1) ZA837480B (da)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2608047B1 (fr) * 1986-12-11 1990-08-31 Roussel Uclaf Compositions zootechniques renfermant un derive de la 6-amino 7-hydroxy 4,5,6,7-tetrahydroimidazo /4,5,1-j-k/ /1/ benzazepin-2-(1h)-one
FR2608046B1 (fr) * 1986-12-11 1989-03-31 Roussel Uclaf Compositions zootechniques renfermant un derive de la 6-amino 7-hydroxy 4,5,6,7-tetrahydroimidazo /4,5, 1-j-k/ /1/benzazepin-2-(1h)-one
AU616390B2 (en) * 1986-12-11 1991-10-31 Hoechst Roussel Vet S.A. Zootechnical compositions containing a beta-adrenergic
IE60964B1 (en) * 1986-12-11 1994-09-07 Roussel Uclaf Zootechnical compositions containing a beta-adrenergic
GB8806449D0 (en) * 1988-03-18 1988-04-20 Janssen Pharmaceutica Nv Antiviral hexahydroimiazo(1 4)benzodiazepin-2-ones
IL93136A (en) * 1989-02-23 1995-01-24 Janssen Pharmaceutica Nv History of tetrahydroimidazo [1,4] benzodiazepine-2-thione, their preparation and pharmaceutical preparations containing them
FR2735474B1 (fr) * 1995-06-13 1997-08-08 Roussel Uclaf Chlorhydrate de zilpaterol sous une forme cristallisee particuliere, son procede de preparation et les produits intermediaires mis en oeuvre
US7207289B2 (en) * 2004-05-20 2007-04-24 Intervet International B.V. Method of feeding the cattle with feed additives that increases beef production and reduces liver abscess
KR20090071632A (ko) * 2006-10-13 2009-07-01 화이자 리미티드 가축 동물에 대한 동화 제제로서 유용한 헤테로사이클릭 화합물
WO2008050207A1 (en) * 2006-10-25 2008-05-02 Pfizer Limited Heterocyclic compounds useful as anabolic agents for livestock animals
JP5126626B2 (ja) * 2007-02-01 2013-01-23 インターベツト・インターナシヨナル・ベー・ベー ６−アミノ−７−ヒドロキシ−４，５，６，７−テトラヒドロ−イミダゾ［４，５，１−ｊｋ］［１］−ベンゾアゼピン−２［１ｈ］−オンおよびジルパテロールのエナンチオ選択的合成
RU2442786C2 (ru) * 2007-03-31 2012-02-20 Интервет Интернэшнл Б.В. Способы получения зилпатерола и его солей
US8362006B2 (en) * 2007-03-31 2013-01-29 Intervet International B.V. Processes for making zilpaterol and salts thereof
SG10201405734UA (en) 2007-03-31 2014-10-30 Intervet Int Bv Processes For Making Zilpaterol And Salts Thereof
HK1136565A1 (en) * 2007-03-31 2010-07-02 Intervet Int Bv Processes for making zilpaterol and salts thereof
EP1995248A1 (en) * 2007-05-23 2008-11-26 Evonik Degussa GmbH Process for the production of amino alcohols by asymmetric hydrogenation
CA2708044C (en) 2007-12-06 2017-01-03 Mary Irene Wray Combination therapies using melengestrol acetate and zilpaterol or its salts
TW201033217A (en) * 2008-12-17 2010-09-16 Intervet Int Bv Process for making a crystalline zilpaterol salt
RU2635695C2 (ru) 2012-05-18 2017-11-15 Интервет Интернэшнл Б.В. Способ усиления прироста кур-бройлеров
MX361888B (es) * 2012-12-18 2018-12-17 Intervet Int Bv Un procedimiento mejorado para producir zilpaterol.
MX2015012726A (es) 2013-03-15 2016-02-18 Intervet Int Bv Metodo para mejorar la eficiencia de la produccion de carne de animales bovinos.
CN104418808A (zh) * 2013-09-11 2015-03-18 中美华世通生物医药科技（武汉）有限公司 一种适于工业化生产的中间体Buzolic acid的制备方法
CN103554113B (zh) * 2013-09-25 2016-04-27 湖北美天生物科技有限公司 一种盐酸齐帕特罗的合成方法
US10231472B2 (en) 2015-07-21 2019-03-19 Intervet Inc. Zilpaterol animal premix formulation
EP3488705A1 (en) 2017-11-23 2019-05-29 Saviela AG Solubilized growth promoting product to be applied orally to animals and method for the respective feed preparation
CN108752352B (zh) * 2018-04-18 2019-11-26 江苏凌云药业股份有限公司 一种盐酸齐帕特罗的合成方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2320439A (en) * 1943-06-01 Bottle carrier
US3200123A (en) * 1962-01-26 1965-08-10 Richardson Merreil Inc Imidazoquinolines
EP0034989B1 (fr) * 1980-02-26 1983-10-05 Roussel-Uclaf Nouveaux dérivés du cycloheptindolol et leurs sels avec les acides, leur préparation, leur application comme médicaments et les compositions les renfermant

Also Published As

Publication number Publication date
JPH0454671B2 (da) 1992-08-31
MX8495A (es) 1993-09-01
FI833697A0 (fi) 1983-10-11
DK466483D0 (da) 1983-10-11
EP0107569B1 (fr) 1987-03-18
GR78731B (da) 1984-10-02
IL69993A (en) 1987-10-30
PH20031A (en) 1986-09-04
FR2534257B1 (da) 1984-12-28
AU2005383A (en) 1984-04-19
KR900006753B1 (ko) 1990-09-20
ES526390A0 (es) 1984-06-16
ATE25981T1 (de) 1987-04-15
CA1216847A (fr) 1987-01-20
EP0107569A1 (fr) 1984-05-02
DE3370332D1 (en) 1987-04-23
IL69993A0 (en) 1984-01-31
CA1222246A (fr) 1987-05-26
HU188499B (en) 1986-04-28
FI833697A (fi) 1984-04-13
DD215784A5 (de) 1984-11-21
IE832387L (en) 1984-04-12
AU559422B2 (en) 1987-03-12
IE59441B1 (en) 1994-02-23
ZA837480B (en) 1984-11-28
SU1384201A3 (ru) 1988-03-23
US4585770A (en) 1986-04-29
FI76340B (fi) 1988-06-30
NZ205918A (en) 1985-12-13
FI76340C (fi) 1988-10-10
DK163734B (da) 1992-03-30
ES8405802A1 (es) 1984-06-16
DK163734C (da) 1992-08-31
PT77469B (fr) 1986-05-07
JPS59130289A (ja) 1984-07-26
FR2534257A1 (fr) 1984-04-13
PT77469A (fr) 1983-11-01
KR840006484A (ko) 1984-11-30
SU1287753A3 (ru) 1987-01-30

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