SU1091858A3 - Способ получени производных азепина или их солей - Google Patents

Способ получени производных азепина или их солей Download PDF

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Publication number
SU1091858A3
SU1091858A3 SU823388045A SU3388045A SU1091858A3 SU 1091858 A3 SU1091858 A3 SU 1091858A3 SU 823388045 A SU823388045 A SU 823388045A SU 3388045 A SU3388045 A SU 3388045A SU 1091858 A3 SU1091858 A3 SU 1091858A3
Authority
SU
USSR - Soviet Union
Prior art keywords
azepine
tetrahydro
calculated
found
hydrogen atom
Prior art date
Application number
SU823388045A
Other languages
English (en)
Russian (ru)
Inventor
Заутер Роберт
Грис Герхарт
Грель Вольфганг
Гурнаус Рудольф
Эйселе Бернхард
Гаарманн Вальтер
Руппрехт Экард
Original Assignee
Др.Карл Томэ Гмбх (Фирма)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Др.Карл Томэ Гмбх (Фирма) filed Critical Др.Карл Томэ Гмбх (Фирма)
Application granted granted Critical
Publication of SU1091858A3 publication Critical patent/SU1091858A3/ru

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
SU823388045A 1981-02-18 1982-02-11 Способ получени производных азепина или их солей SU1091858A3 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19813105858 DE3105858A1 (de) 1981-02-18 1981-02-18 "neue thieno-azepine, ihre herstellung und ihre verwendung als arzneimittel"

Publications (1)

Publication Number Publication Date
SU1091858A3 true SU1091858A3 (ru) 1984-05-07

Family

ID=6125118

Family Applications (1)

Application Number Title Priority Date Filing Date
SU823388045A SU1091858A3 (ru) 1981-02-18 1982-02-11 Способ получени производных азепина или их солей

Country Status (26)

Country Link
US (1) US4414225A (enExample)
EP (1) EP0058341B1 (enExample)
JP (1) JPS57150687A (enExample)
AR (1) AR231983A1 (enExample)
AT (1) ATE13298T1 (enExample)
AU (1) AU547951B2 (enExample)
CA (1) CA1171084A (enExample)
CS (1) CS227039B2 (enExample)
DD (1) DD202577A5 (enExample)
DE (2) DE3105858A1 (enExample)
DK (1) DK150157C (enExample)
ES (4) ES509682A0 (enExample)
FI (1) FI820509L (enExample)
GB (1) GB2093030B (enExample)
GR (1) GR76793B (enExample)
HU (1) HU190984B (enExample)
IE (1) IE52540B1 (enExample)
IL (1) IL65051A (enExample)
NO (1) NO157503C (enExample)
NZ (1) NZ199759A (enExample)
PH (1) PH17724A (enExample)
PL (1) PL137354B1 (enExample)
PT (1) PT74447B (enExample)
SU (1) SU1091858A3 (enExample)
YU (1) YU34982A (enExample)
ZA (1) ZA821020B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2434872C2 (ru) * 2006-01-19 2011-11-27 Атерсис, Инк. Тиофенильные и пирролильные азепины в качестве лигандов серотонинового 5-ht2c рецептора и их применение

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4520025A (en) * 1982-07-21 1985-05-28 William H. Rorer, Inc. Bicyclic nitrogen heterocyclic ethers and thioethers, and their pharmaceutical uses
DE3230696A1 (de) * 1982-08-18 1984-02-23 Dr. Karl Thomae Gmbh, 7950 Biberach Neue thieno-thiazol-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
GB8800891D0 (en) * 1988-01-15 1988-02-17 Lilly Industries Ltd Pharmaceutical compounds
GB8909132D0 (en) * 1989-04-21 1989-06-07 Lilly Industries Ltd Pharmaceutical compounds
FR2652579B1 (fr) * 1989-10-02 1992-01-24 Sanofi Sa Derives d'hydroxy-2 thiophene et furanne condenses avec un cycle azote, sur procede de preparation et leur application en therapeutique.
GB9025890D0 (en) * 1990-11-28 1991-01-09 Lilly Industries Ltd Pharmaceutical compounds
US5532240A (en) * 1991-12-26 1996-07-02 Yoshitomi Pharmaceutical Industries, Ltd. Condensed thiophene compound and pharmaceutical use thereof
EP0596125A4 (en) * 1991-12-26 1994-10-05 Yoshitomi Pharmaceutical Condensed thiophene compound and pharmaceutical use thereof.
US5334596A (en) * 1993-05-11 1994-08-02 Merck & Co., Inc. Fibrinogen receptor antagonists
DE4324580A1 (de) * 1993-07-22 1995-01-26 Thomae Gmbh Dr K Bicyclische Heterocyclen, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
US5696112A (en) * 1995-01-17 1997-12-09 American Cyanamid Company Fused heterocyclic azepines as vasopressin antagonists
FR2733750B1 (fr) * 1995-05-03 1997-06-13 Synthelabo Derives de l'acide gamma-oxo-alpha-(phenylmethyl)-5,6- dihydro-4h-thieno(3,4-c)pyrrole-5-butanoique, leur preparation et leur application en therapeutique
US5939417A (en) * 1998-10-19 1999-08-17 Cell Pathways Inc 1,3,6-trihydro-6-aza-3-oxapentalen-2-one derivatives for the treatment of neoplasia
SI1778243T1 (sl) * 2004-06-30 2013-03-29 Athersys, Inc. Substituirani derivati azepina, kot modulatorji receptorja serotonina
DK1796663T3 (da) 2004-09-03 2011-08-15 Athersys Inc Tricykliske heteroaryl-piperaziner, pyrrolidiner og azetidiner som serotonin-receptor-modulatorer
WO2014100815A2 (en) 2012-12-21 2014-06-26 Abt Holding Company Benzazepines as serotonin 5-ht2c receptor ligands and uses thereof
WO2014159067A1 (en) 2013-03-13 2014-10-02 Abt Holding Company Thienylindole azepines as serotonin 5-ht2c receptor ligands and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3849441A (en) * 1971-10-01 1974-11-19 American Cyanamid Co Substituted heterocyclic derivatives of azepine
US3758501A (en) * 1971-10-01 1973-09-11 M Weiss Substituted heterocyclic derivatives of azepine
US3846446A (en) * 1971-10-01 1974-11-05 American Cyanamid Co Substituted heterocyclic derivatives of azepine

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
1. Эльдерфильд. Гетероциклические соединени . М., 1954, т. 2, с, 15. 115. 2. Патент СССР № 461507, кл. С.07 D 513/04, 1970. *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2434872C2 (ru) * 2006-01-19 2011-11-27 Атерсис, Инк. Тиофенильные и пирролильные азепины в качестве лигандов серотонинового 5-ht2c рецептора и их применение

Also Published As

Publication number Publication date
IL65051A (en) 1986-11-30
DK150157C (da) 1987-06-29
ATE13298T1 (de) 1985-06-15
HU190984B (en) 1986-12-28
CA1171084A (en) 1984-07-17
PL235121A1 (enExample) 1982-10-25
US4414225A (en) 1983-11-08
IE820338L (en) 1982-08-18
JPS57150687A (en) 1982-09-17
IE52540B1 (en) 1987-12-09
ES515729A0 (es) 1983-06-01
DE3263462D1 (en) 1985-06-20
HUT34754A (en) 1985-04-28
AR231983A1 (es) 1985-04-30
ES8306755A1 (es) 1983-06-01
PL137354B1 (en) 1986-05-31
EP0058341A1 (de) 1982-08-25
NO157503C (no) 1988-03-30
PT74447B (de) 1984-10-09
GR76793B (enExample) 1984-09-04
ES8306753A1 (es) 1983-06-01
AU8055282A (en) 1982-08-26
PH17724A (en) 1984-11-21
GB2093030A (en) 1982-08-25
PT74447A (de) 1982-03-01
FI820509A7 (fi) 1982-08-19
ES8304987A1 (es) 1983-03-16
NO820493L (no) 1982-08-19
ES509682A0 (es) 1983-03-16
NO157503B (no) 1987-12-21
DK69382A (da) 1982-08-19
EP0058341B1 (de) 1985-05-15
NZ199759A (en) 1985-09-13
GB2093030B (en) 1985-01-16
ZA821020B (en) 1983-10-26
DE3105858A1 (de) 1982-09-02
ES515728A0 (es) 1983-06-01
ES515730A0 (es) 1983-06-01
DK150157B (da) 1986-12-22
CS227039B2 (en) 1984-04-16
FI820509L (fi) 1982-08-19
AU547951B2 (en) 1985-11-14
IL65051A0 (en) 1982-04-30
ES8306754A1 (es) 1983-06-01
DD202577A5 (de) 1983-09-21
YU34982A (en) 1985-04-30

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