DK69382A - Fremgangsmaade til fremstilling af azepinderivater eller saltederaf - Google Patents

Fremgangsmaade til fremstilling af azepinderivater eller saltederaf Download PDF

Info

Publication number
DK69382A
DK69382A DK69382A DK69382A DK69382A DK 69382 A DK69382 A DK 69382A DK 69382 A DK69382 A DK 69382A DK 69382 A DK69382 A DK 69382A DK 69382 A DK69382 A DK 69382A
Authority
DK
Denmark
Prior art keywords
salts
procedure
preparation
azepine derivatives
azepine
Prior art date
Application number
DK69382A
Other languages
English (en)
Other versions
DK150157C (da
DK150157B (da
Inventor
R Sauter
G Griss
W Grell
R Hurnaus
W Haarmann
E Rupprecht
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of DK69382A publication Critical patent/DK69382A/da
Publication of DK150157B publication Critical patent/DK150157B/da
Application granted granted Critical
Publication of DK150157C publication Critical patent/DK150157C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/02Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D223/06Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK069382A 1981-02-18 1982-02-17 Analogifremgangsmaade til fremstilling af furo-, thieno- eller pyrrolo (2,3-d)azepiner eller fysiologisk acceptable salte deraf med syrer eller baser DK150157C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3105858 1981-02-18
DE19813105858 DE3105858A1 (de) 1981-02-18 1981-02-18 "neue thieno-azepine, ihre herstellung und ihre verwendung als arzneimittel"

Publications (3)

Publication Number Publication Date
DK69382A true DK69382A (da) 1982-08-19
DK150157B DK150157B (da) 1986-12-22
DK150157C DK150157C (da) 1987-06-29

Family

ID=6125118

Family Applications (1)

Application Number Title Priority Date Filing Date
DK069382A DK150157C (da) 1981-02-18 1982-02-17 Analogifremgangsmaade til fremstilling af furo-, thieno- eller pyrrolo (2,3-d)azepiner eller fysiologisk acceptable salte deraf med syrer eller baser

Country Status (26)

Country Link
US (1) US4414225A (da)
EP (1) EP0058341B1 (da)
JP (1) JPS57150687A (da)
AR (1) AR231983A1 (da)
AT (1) ATE13298T1 (da)
AU (1) AU547951B2 (da)
CA (1) CA1171084A (da)
CS (1) CS227039B2 (da)
DD (1) DD202577A5 (da)
DE (2) DE3105858A1 (da)
DK (1) DK150157C (da)
ES (4) ES509682A0 (da)
FI (1) FI820509L (da)
GB (1) GB2093030B (da)
GR (1) GR76793B (da)
HU (1) HU190984B (da)
IE (1) IE52540B1 (da)
IL (1) IL65051A (da)
NO (1) NO157503C (da)
NZ (1) NZ199759A (da)
PH (1) PH17724A (da)
PL (1) PL137354B1 (da)
PT (1) PT74447B (da)
SU (1) SU1091858A3 (da)
YU (1) YU34982A (da)
ZA (1) ZA821020B (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4520025A (en) * 1982-07-21 1985-05-28 William H. Rorer, Inc. Bicyclic nitrogen heterocyclic ethers and thioethers, and their pharmaceutical uses
DE3230696A1 (de) * 1982-08-18 1984-02-23 Dr. Karl Thomae Gmbh, 7950 Biberach Neue thieno-thiazol-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
GB8800891D0 (en) * 1988-01-15 1988-02-17 Lilly Industries Ltd Pharmaceutical compounds
GB8909132D0 (en) * 1989-04-21 1989-06-07 Lilly Industries Ltd Pharmaceutical compounds
FR2652579B1 (fr) * 1989-10-02 1992-01-24 Sanofi Sa Derives d'hydroxy-2 thiophene et furanne condenses avec un cycle azote, sur procede de preparation et leur application en therapeutique.
GB9025890D0 (en) * 1990-11-28 1991-01-09 Lilly Industries Ltd Pharmaceutical compounds
KR930703327A (ko) * 1991-12-26 1993-11-29 고야 다다시 축합형 티오펜 화합물 및 그의 의약용도
US5532240A (en) * 1991-12-26 1996-07-02 Yoshitomi Pharmaceutical Industries, Ltd. Condensed thiophene compound and pharmaceutical use thereof
US5334596A (en) * 1993-05-11 1994-08-02 Merck & Co., Inc. Fibrinogen receptor antagonists
DE4324580A1 (de) * 1993-07-22 1995-01-26 Thomae Gmbh Dr K Bicyclische Heterocyclen, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
US5696112A (en) * 1995-01-17 1997-12-09 American Cyanamid Company Fused heterocyclic azepines as vasopressin antagonists
FR2733750B1 (fr) * 1995-05-03 1997-06-13 Synthelabo Derives de l'acide gamma-oxo-alpha-(phenylmethyl)-5,6- dihydro-4h-thieno(3,4-c)pyrrole-5-butanoique, leur preparation et leur application en therapeutique
US5939417A (en) * 1998-10-19 1999-08-17 Cell Pathways Inc 1,3,6-trihydro-6-aza-3-oxapentalen-2-one derivatives for the treatment of neoplasia
NZ550891A (en) * 2004-06-30 2009-10-30 Athersys Inc Substituted azepine derivatives as serotonin receptor modulators
ATE507832T1 (de) * 2004-09-03 2011-05-15 Athersys Inc Trizyklische heteroaryl-piperazine, pyrrolidine und azetidine als serotonin-rezeptor-modulatoren
BRPI0707183A2 (pt) * 2006-01-19 2011-04-26 Athersys Inc composto, composição farmacêutica, e, método de tratar uma doença, distúrbio e/ou condição em um paciente
AU2013364022A1 (en) 2012-12-21 2015-07-02 Abt Holding Company Benzazepines as serotonin 5-HT2C receptor ligands and uses thereof
US9309262B2 (en) 2013-03-13 2016-04-12 Abt Holding Company Thienylindole azepines as serotonin 5-HT2C receptor ligands and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3846446A (en) * 1971-10-01 1974-11-05 American Cyanamid Co Substituted heterocyclic derivatives of azepine
US3849441A (en) * 1971-10-01 1974-11-19 American Cyanamid Co Substituted heterocyclic derivatives of azepine
US3758501A (en) * 1971-10-01 1973-09-11 M Weiss Substituted heterocyclic derivatives of azepine

Also Published As

Publication number Publication date
IL65051A (en) 1986-11-30
ES8304987A1 (es) 1983-03-16
SU1091858A3 (ru) 1984-05-07
JPS57150687A (en) 1982-09-17
NO157503C (no) 1988-03-30
EP0058341B1 (de) 1985-05-15
ES8306753A1 (es) 1983-06-01
PH17724A (en) 1984-11-21
IL65051A0 (en) 1982-04-30
GR76793B (da) 1984-09-04
DK150157C (da) 1987-06-29
FI820509L (fi) 1982-08-19
NO820493L (no) 1982-08-19
GB2093030A (en) 1982-08-25
DK150157B (da) 1986-12-22
DD202577A5 (de) 1983-09-21
NO157503B (no) 1987-12-21
HU190984B (en) 1986-12-28
NZ199759A (en) 1985-09-13
PL137354B1 (en) 1986-05-31
IE820338L (en) 1982-08-18
HUT34754A (en) 1985-04-28
ES8306755A1 (es) 1983-06-01
ZA821020B (en) 1983-10-26
AU8055282A (en) 1982-08-26
GB2093030B (en) 1985-01-16
PT74447B (de) 1984-10-09
YU34982A (en) 1985-04-30
DE3105858A1 (de) 1982-09-02
ES515729A0 (es) 1983-06-01
CA1171084A (en) 1984-07-17
PT74447A (de) 1982-03-01
ATE13298T1 (de) 1985-06-15
PL235121A1 (da) 1982-10-25
ES515730A0 (es) 1983-06-01
US4414225A (en) 1983-11-08
AR231983A1 (es) 1985-04-30
IE52540B1 (en) 1987-12-09
EP0058341A1 (de) 1982-08-25
DE3263462D1 (en) 1985-06-20
CS227039B2 (en) 1984-04-16
ES8306754A1 (es) 1983-06-01
ES515728A0 (es) 1983-06-01
AU547951B2 (en) 1985-11-14
ES509682A0 (es) 1983-03-16

Similar Documents

Publication Publication Date Title
DK112582A (da) Fremgangsmaade til fremstilling af triazolonderivater
DK66582A (da) Fremgangsmaade til fremstilling af carbostyrilderivater
DK50482A (da) Fremgangsmaade til fremstilling af quinazolinderivater
DK346382A (da) Fremgangsmaade til fremstilling af gangliosidderivater
DK316582A (da) Fremgangsmaade til fremstilling af bicykliske pyrimidin-5-on-derivater
DK69382A (da) Fremgangsmaade til fremstilling af azepinderivater eller saltederaf
DK491582A (da) Fremgangsmaade til fremstilling af morphinanderivater
DK352082A (da) Fremgangsmaade til fremstilling af ergopeptinderivater
DK241982A (da) Fremgangsmaade til fremstilling af carboximidderivater
DK453882A (da) Fremgangsmaade til fremstilling af triazinderivater
DK155984D0 (da) Fremgangsmade til fremstilling af thiadiazolderivater
DK353781A (da) Fremgangsmaade til fremstilling af insulinderivater
DK160555C (da) Fremgangsmaade til fremstilling af eburnamoninderivater
DK116982A (da) Fremgangsmaade til fremstilling af alkylendioxybenzenderivater
DK312584D0 (da) Fremgangsmaade til fremstilling af quinonderivater
DK140584D0 (da) Fremgangsmaade til fremstilling af carbapenemderivater
DK438482A (da) Fremgangsmaade til fremstilling af indanderivater eller syreadditionssalte deraf
DK375882A (da) Fremgangsmaade til fremstilling af benzisoxazolderivater
DK553982A (da) Fremgangsmaade til fremstilling af omt-esterderivater eller syreadditionssalte deraf
DK70482A (da) Fremgangsmaade til fremstilling af diazolderivater
DK476082A (da) Fremgangsmaade til fremstilling af phenolderivater eller salte deraf
DK158224C (da) Fremgangsmaade til fremstilling af indolderivater
DK328182A (da) Fremgangsmaade til fremstilling af phospholipidderivater
DK289382A (da) Fremgangsmaade til fremstilling af hidtil ukendte derivater af benzoylphenylpiperidin
DK57182A (da) Fremgangsmaade til fremstilling af benzopyranoimidazoler ellersyreadditionssalte eller metalsalte deraf

Legal Events

Date Code Title Description
PBP Patent lapsed