DK69382A - Fremgangsmaade til fremstilling af azepinderivater eller saltederaf - Google Patents
Fremgangsmaade til fremstilling af azepinderivater eller saltederaf Download PDFInfo
- Publication number
- DK69382A DK69382A DK69382A DK69382A DK69382A DK 69382 A DK69382 A DK 69382A DK 69382 A DK69382 A DK 69382A DK 69382 A DK69382 A DK 69382A DK 69382 A DK69382 A DK 69382A
- Authority
- DK
- Denmark
- Prior art keywords
- salts
- procedure
- preparation
- azepine derivatives
- azepine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Hematology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3105858 | 1981-02-18 | ||
| DE19813105858 DE3105858A1 (de) | 1981-02-18 | 1981-02-18 | "neue thieno-azepine, ihre herstellung und ihre verwendung als arzneimittel" |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK69382A true DK69382A (da) | 1982-08-19 |
| DK150157B DK150157B (da) | 1986-12-22 |
| DK150157C DK150157C (da) | 1987-06-29 |
Family
ID=6125118
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK069382A DK150157C (da) | 1981-02-18 | 1982-02-17 | Analogifremgangsmaade til fremstilling af furo-, thieno- eller pyrrolo (2,3-d)azepiner eller fysiologisk acceptable salte deraf med syrer eller baser |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US4414225A (da) |
| EP (1) | EP0058341B1 (da) |
| JP (1) | JPS57150687A (da) |
| AR (1) | AR231983A1 (da) |
| AT (1) | ATE13298T1 (da) |
| AU (1) | AU547951B2 (da) |
| CA (1) | CA1171084A (da) |
| CS (1) | CS227039B2 (da) |
| DD (1) | DD202577A5 (da) |
| DE (2) | DE3105858A1 (da) |
| DK (1) | DK150157C (da) |
| ES (4) | ES8304987A1 (da) |
| FI (1) | FI820509L (da) |
| GB (1) | GB2093030B (da) |
| GR (1) | GR76793B (da) |
| HU (1) | HU190984B (da) |
| IE (1) | IE52540B1 (da) |
| IL (1) | IL65051A (da) |
| NO (1) | NO157503C (da) |
| NZ (1) | NZ199759A (da) |
| PH (1) | PH17724A (da) |
| PL (1) | PL137354B1 (da) |
| PT (1) | PT74447B (da) |
| SU (1) | SU1091858A3 (da) |
| YU (1) | YU34982A (da) |
| ZA (1) | ZA821020B (da) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4520025A (en) * | 1982-07-21 | 1985-05-28 | William H. Rorer, Inc. | Bicyclic nitrogen heterocyclic ethers and thioethers, and their pharmaceutical uses |
| DE3230696A1 (de) * | 1982-08-18 | 1984-02-23 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue thieno-thiazol-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| GB8800891D0 (en) * | 1988-01-15 | 1988-02-17 | Lilly Industries Ltd | Pharmaceutical compounds |
| GB8909132D0 (en) * | 1989-04-21 | 1989-06-07 | Lilly Industries Ltd | Pharmaceutical compounds |
| FR2652579B1 (fr) * | 1989-10-02 | 1992-01-24 | Sanofi Sa | Derives d'hydroxy-2 thiophene et furanne condenses avec un cycle azote, sur procede de preparation et leur application en therapeutique. |
| GB9025890D0 (en) * | 1990-11-28 | 1991-01-09 | Lilly Industries Ltd | Pharmaceutical compounds |
| EP0596125A4 (en) * | 1991-12-26 | 1994-10-05 | Yoshitomi Pharmaceutical | Condensed thiophene compound and pharmaceutical use thereof. |
| US5532240A (en) * | 1991-12-26 | 1996-07-02 | Yoshitomi Pharmaceutical Industries, Ltd. | Condensed thiophene compound and pharmaceutical use thereof |
| US5334596A (en) * | 1993-05-11 | 1994-08-02 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
| DE4324580A1 (de) * | 1993-07-22 | 1995-01-26 | Thomae Gmbh Dr K | Bicyclische Heterocyclen, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung |
| US5696112A (en) * | 1995-01-17 | 1997-12-09 | American Cyanamid Company | Fused heterocyclic azepines as vasopressin antagonists |
| FR2733750B1 (fr) * | 1995-05-03 | 1997-06-13 | Synthelabo | Derives de l'acide gamma-oxo-alpha-(phenylmethyl)-5,6- dihydro-4h-thieno(3,4-c)pyrrole-5-butanoique, leur preparation et leur application en therapeutique |
| US5939417A (en) * | 1998-10-19 | 1999-08-17 | Cell Pathways Inc | 1,3,6-trihydro-6-aza-3-oxapentalen-2-one derivatives for the treatment of neoplasia |
| CA2565683C (en) * | 2004-06-30 | 2013-04-02 | Athersys, Inc. | Substituted azepine derivatives as serotonin receptor modulators |
| US7423056B2 (en) * | 2004-09-03 | 2008-09-09 | Athersys, Inc. | Tricyclic heteroaryl piperazines, pyrrolidines and azetidines as serotonin receptor modulators |
| RU2434872C2 (ru) | 2006-01-19 | 2011-11-27 | Атерсис, Инк. | Тиофенильные и пирролильные азепины в качестве лигандов серотонинового 5-ht2c рецептора и их применение |
| JP2016503808A (ja) | 2012-12-21 | 2016-02-08 | エイビーティー ホールディング カンパニー | セロトニン５−ＨＴ２ｃ受容体リガンドとしてのベンザゼピンおよびその使用 |
| US9309262B2 (en) | 2013-03-13 | 2016-04-12 | Abt Holding Company | Thienylindole azepines as serotonin 5-HT2C receptor ligands and uses thereof |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3758501A (en) * | 1971-10-01 | 1973-09-11 | M Weiss | Substituted heterocyclic derivatives of azepine |
| US3846446A (en) * | 1971-10-01 | 1974-11-05 | American Cyanamid Co | Substituted heterocyclic derivatives of azepine |
| US3849441A (en) * | 1971-10-01 | 1974-11-19 | American Cyanamid Co | Substituted heterocyclic derivatives of azepine |
-
1981
- 1981-02-17 ZA ZA821020A patent/ZA821020B/xx unknown
- 1981-02-18 DE DE19813105858 patent/DE3105858A1/de not_active Withdrawn
-
1982
- 1982-02-03 DE DE8282100745T patent/DE3263462D1/de not_active Expired
- 1982-02-03 EP EP82100745A patent/EP0058341B1/de not_active Expired
- 1982-02-03 AT AT82100745T patent/ATE13298T1/de not_active IP Right Cessation
- 1982-02-11 SU SU823388045A patent/SU1091858A3/ru active
- 1982-02-12 US US06/348,496 patent/US4414225A/en not_active Expired - Fee Related
- 1982-02-15 GR GR67317A patent/GR76793B/el unknown
- 1982-02-16 DD DD82237445A patent/DD202577A5/de unknown
- 1982-02-16 PH PH26951A patent/PH17724A/en unknown
- 1982-02-16 FI FI820509A patent/FI820509L/fi not_active Application Discontinuation
- 1982-02-16 CA CA000396329A patent/CA1171084A/en not_active Expired
- 1982-02-17 JP JP57024249A patent/JPS57150687A/ja active Pending
- 1982-02-17 NO NO820493A patent/NO157503C/no unknown
- 1982-02-17 YU YU00349/82A patent/YU34982A/xx unknown
- 1982-02-17 PT PT74447A patent/PT74447B/pt unknown
- 1982-02-17 GB GB8204585A patent/GB2093030B/en not_active Expired
- 1982-02-17 AU AU80552/82A patent/AU547951B2/en not_active Ceased
- 1982-02-17 IE IE338/82A patent/IE52540B1/en unknown
- 1982-02-17 NZ NZ199759A patent/NZ199759A/xx unknown
- 1982-02-17 DK DK069382A patent/DK150157C/da not_active IP Right Cessation
- 1982-02-17 ES ES509682A patent/ES8304987A1/es not_active Expired
- 1982-02-17 PL PL1982235121A patent/PL137354B1/pl unknown
- 1982-02-18 HU HU82499A patent/HU190984B/hu unknown
- 1982-02-18 CS CS821126A patent/CS227039B2/cs unknown
- 1982-02-18 AR AR288469A patent/AR231983A1/es active
- 1982-02-18 IL IL65051A patent/IL65051A/xx unknown
- 1982-09-15 ES ES515729A patent/ES515729A0/es active Granted
- 1982-09-15 ES ES515728A patent/ES8306753A1/es not_active Expired
- 1982-09-15 ES ES515730A patent/ES8306755A1/es not_active Expired
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PBP | Patent lapsed |