ES509682A0 - "procedimiento para la preparacion de nuevos derivados de azepina". - Google Patents

"procedimiento para la preparacion de nuevos derivados de azepina".

Info

Publication number
ES509682A0
ES509682A0 ES509682A ES509682A ES509682A0 ES 509682 A0 ES509682 A0 ES 509682A0 ES 509682 A ES509682 A ES 509682A ES 509682 A ES509682 A ES 509682A ES 509682 A0 ES509682 A0 ES 509682A0
Authority
ES
Spain
Prior art keywords
azepina
procedure
preparation
new derivatives
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES509682A
Other languages
English (en)
Other versions
ES8304987A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Publication of ES509682A0 publication Critical patent/ES509682A0/es
Publication of ES8304987A1 publication Critical patent/ES8304987A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ES509682A 1981-02-18 1982-02-17 "procedimiento para la preparacion de nuevos derivados de azepina". Expired ES8304987A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19813105858 DE3105858A1 (de) 1981-02-18 1981-02-18 "neue thieno-azepine, ihre herstellung und ihre verwendung als arzneimittel"

Publications (2)

Publication Number Publication Date
ES509682A0 true ES509682A0 (es) 1983-03-16
ES8304987A1 ES8304987A1 (es) 1983-03-16

Family

ID=6125118

Family Applications (4)

Application Number Title Priority Date Filing Date
ES509682A Expired ES8304987A1 (es) 1981-02-18 1982-02-17 "procedimiento para la preparacion de nuevos derivados de azepina".
ES515728A Expired ES8306753A1 (es) 1981-02-18 1982-09-15 "procedimiento para la preparacion de nuevos derivados de azepina".
ES515730A Granted ES515730A0 (es) 1981-02-18 1982-09-15 "procedimiento para la preparacion de nuevos derivados de azepina".
ES515729A Granted ES515729A0 (es) 1981-02-18 1982-09-15 "procedimiento para la preparacion de nuevos derivados de azepina".

Family Applications After (3)

Application Number Title Priority Date Filing Date
ES515728A Expired ES8306753A1 (es) 1981-02-18 1982-09-15 "procedimiento para la preparacion de nuevos derivados de azepina".
ES515730A Granted ES515730A0 (es) 1981-02-18 1982-09-15 "procedimiento para la preparacion de nuevos derivados de azepina".
ES515729A Granted ES515729A0 (es) 1981-02-18 1982-09-15 "procedimiento para la preparacion de nuevos derivados de azepina".

Country Status (26)

Country Link
US (1) US4414225A (es)
EP (1) EP0058341B1 (es)
JP (1) JPS57150687A (es)
AR (1) AR231983A1 (es)
AT (1) ATE13298T1 (es)
AU (1) AU547951B2 (es)
CA (1) CA1171084A (es)
CS (1) CS227039B2 (es)
DD (1) DD202577A5 (es)
DE (2) DE3105858A1 (es)
DK (1) DK150157C (es)
ES (4) ES8304987A1 (es)
FI (1) FI820509L (es)
GB (1) GB2093030B (es)
GR (1) GR76793B (es)
HU (1) HU190984B (es)
IE (1) IE52540B1 (es)
IL (1) IL65051A (es)
NO (1) NO157503C (es)
NZ (1) NZ199759A (es)
PH (1) PH17724A (es)
PL (1) PL137354B1 (es)
PT (1) PT74447B (es)
SU (1) SU1091858A3 (es)
YU (1) YU34982A (es)
ZA (1) ZA821020B (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4520025A (en) * 1982-07-21 1985-05-28 William H. Rorer, Inc. Bicyclic nitrogen heterocyclic ethers and thioethers, and their pharmaceutical uses
DE3230696A1 (de) * 1982-08-18 1984-02-23 Dr. Karl Thomae Gmbh, 7950 Biberach Neue thieno-thiazol-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
GB8800891D0 (en) * 1988-01-15 1988-02-17 Lilly Industries Ltd Pharmaceutical compounds
GB8909132D0 (en) * 1989-04-21 1989-06-07 Lilly Industries Ltd Pharmaceutical compounds
FR2652579B1 (fr) * 1989-10-02 1992-01-24 Sanofi Sa Derives d'hydroxy-2 thiophene et furanne condenses avec un cycle azote, sur procede de preparation et leur application en therapeutique.
GB9025890D0 (en) * 1990-11-28 1991-01-09 Lilly Industries Ltd Pharmaceutical compounds
US5532240A (en) * 1991-12-26 1996-07-02 Yoshitomi Pharmaceutical Industries, Ltd. Condensed thiophene compound and pharmaceutical use thereof
WO1993013105A1 (fr) * 1991-12-26 1993-07-08 Yoshitomi Pharmaceutical Industries, Ltd. Compose de thiophene condense et utilisation pharmaceutique de ce compose
US5334596A (en) * 1993-05-11 1994-08-02 Merck & Co., Inc. Fibrinogen receptor antagonists
DE4324580A1 (de) * 1993-07-22 1995-01-26 Thomae Gmbh Dr K Bicyclische Heterocyclen, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
US5696112A (en) * 1995-01-17 1997-12-09 American Cyanamid Company Fused heterocyclic azepines as vasopressin antagonists
FR2733750B1 (fr) * 1995-05-03 1997-06-13 Synthelabo Derives de l'acide gamma-oxo-alpha-(phenylmethyl)-5,6- dihydro-4h-thieno(3,4-c)pyrrole-5-butanoique, leur preparation et leur application en therapeutique
US5939417A (en) * 1998-10-19 1999-08-17 Cell Pathways Inc 1,3,6-trihydro-6-aza-3-oxapentalen-2-one derivatives for the treatment of neoplasia
SI1778243T1 (sl) * 2004-06-30 2013-03-29 Athersys, Inc. Substituirani derivati azepina, kot modulatorji receptorja serotonina
DK1796663T3 (da) 2004-09-03 2011-08-15 Athersys Inc Tricykliske heteroaryl-piperaziner, pyrrolidiner og azetidiner som serotonin-receptor-modulatorer
US7893051B2 (en) 2006-01-19 2011-02-22 Athersys, Inc. Thiophenyl and pyrrolyl azepines as serotonin 5-HT2c receptor ligands and uses thereof
SG11201504749TA (en) 2012-12-21 2015-07-30 Abt Holding Co Benzazepines as serotonin 5-ht2c receptor ligands and uses thereof
US9309262B2 (en) 2013-03-13 2016-04-12 Abt Holding Company Thienylindole azepines as serotonin 5-HT2C receptor ligands and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3849441A (en) * 1971-10-01 1974-11-19 American Cyanamid Co Substituted heterocyclic derivatives of azepine
US3758501A (en) * 1971-10-01 1973-09-11 M Weiss Substituted heterocyclic derivatives of azepine
US3846446A (en) * 1971-10-01 1974-11-05 American Cyanamid Co Substituted heterocyclic derivatives of azepine

Also Published As

Publication number Publication date
PH17724A (en) 1984-11-21
ES8306755A1 (es) 1983-06-01
CA1171084A (en) 1984-07-17
PL235121A1 (es) 1982-10-25
NO157503C (no) 1988-03-30
CS227039B2 (en) 1984-04-16
IL65051A0 (en) 1982-04-30
IE52540B1 (en) 1987-12-09
GR76793B (es) 1984-09-04
HU190984B (en) 1986-12-28
JPS57150687A (en) 1982-09-17
ES8306754A1 (es) 1983-06-01
ES515730A0 (es) 1983-06-01
PT74447B (de) 1984-10-09
DE3105858A1 (de) 1982-09-02
YU34982A (en) 1985-04-30
ES515729A0 (es) 1983-06-01
ATE13298T1 (de) 1985-06-15
EP0058341B1 (de) 1985-05-15
IL65051A (en) 1986-11-30
AR231983A1 (es) 1985-04-30
NO820493L (no) 1982-08-19
SU1091858A3 (ru) 1984-05-07
EP0058341A1 (de) 1982-08-25
NO157503B (no) 1987-12-21
GB2093030B (en) 1985-01-16
ZA821020B (en) 1983-10-26
DK150157B (da) 1986-12-22
AU547951B2 (en) 1985-11-14
ES515728A0 (es) 1983-06-01
AU8055282A (en) 1982-08-26
DD202577A5 (de) 1983-09-21
NZ199759A (en) 1985-09-13
PL137354B1 (en) 1986-05-31
IE820338L (en) 1982-08-18
PT74447A (de) 1982-03-01
ES8306753A1 (es) 1983-06-01
US4414225A (en) 1983-11-08
FI820509L (fi) 1982-08-19
DE3263462D1 (en) 1985-06-20
DK69382A (da) 1982-08-19
HUT34754A (en) 1985-04-28
ES8304987A1 (es) 1983-03-16
GB2093030A (en) 1982-08-25
DK150157C (da) 1987-06-29

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