PH17724A - Azepine derivatives and their anti-thrombotic compositions and methods - Google Patents
Azepine derivatives and their anti-thrombotic compositions and methodsInfo
- Publication number
- PH17724A PH17724A PH26951A PH26951A PH17724A PH 17724 A PH17724 A PH 17724A PH 26951 A PH26951 A PH 26951A PH 26951 A PH26951 A PH 26951A PH 17724 A PH17724 A PH 17724A
- Authority
- PH
- Philippines
- Prior art keywords
- methods
- azepine derivatives
- thrombotic
- compositions
- thrombotic compositions
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19813105858 DE3105858A1 (de) | 1981-02-18 | 1981-02-18 | "neue thieno-azepine, ihre herstellung und ihre verwendung als arzneimittel" |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PH17724A true PH17724A (en) | 1984-11-21 |
Family
ID=6125118
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PH26951A PH17724A (en) | 1981-02-18 | 1982-02-16 | Azepine derivatives and their anti-thrombotic compositions and methods |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US4414225A (es) |
| EP (1) | EP0058341B1 (es) |
| JP (1) | JPS57150687A (es) |
| AR (1) | AR231983A1 (es) |
| AT (1) | ATE13298T1 (es) |
| AU (1) | AU547951B2 (es) |
| CA (1) | CA1171084A (es) |
| CS (1) | CS227039B2 (es) |
| DD (1) | DD202577A5 (es) |
| DE (2) | DE3105858A1 (es) |
| DK (1) | DK150157C (es) |
| ES (4) | ES8304987A1 (es) |
| FI (1) | FI820509L (es) |
| GB (1) | GB2093030B (es) |
| GR (1) | GR76793B (es) |
| HU (1) | HU190984B (es) |
| IE (1) | IE52540B1 (es) |
| IL (1) | IL65051A (es) |
| NO (1) | NO157503C (es) |
| NZ (1) | NZ199759A (es) |
| PH (1) | PH17724A (es) |
| PL (1) | PL137354B1 (es) |
| PT (1) | PT74447B (es) |
| SU (1) | SU1091858A3 (es) |
| YU (1) | YU34982A (es) |
| ZA (1) | ZA821020B (es) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4520025A (en) * | 1982-07-21 | 1985-05-28 | William H. Rorer, Inc. | Bicyclic nitrogen heterocyclic ethers and thioethers, and their pharmaceutical uses |
| DE3230696A1 (de) * | 1982-08-18 | 1984-02-23 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue thieno-thiazol-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| GB8800891D0 (en) * | 1988-01-15 | 1988-02-17 | Lilly Industries Ltd | Pharmaceutical compounds |
| GB8909132D0 (en) * | 1989-04-21 | 1989-06-07 | Lilly Industries Ltd | Pharmaceutical compounds |
| FR2652579B1 (fr) * | 1989-10-02 | 1992-01-24 | Sanofi Sa | Derives d'hydroxy-2 thiophene et furanne condenses avec un cycle azote, sur procede de preparation et leur application en therapeutique. |
| GB9025890D0 (en) * | 1990-11-28 | 1991-01-09 | Lilly Industries Ltd | Pharmaceutical compounds |
| KR930703327A (ko) * | 1991-12-26 | 1993-11-29 | 고야 다다시 | 축합형 티오펜 화합물 및 그의 의약용도 |
| US5532240A (en) * | 1991-12-26 | 1996-07-02 | Yoshitomi Pharmaceutical Industries, Ltd. | Condensed thiophene compound and pharmaceutical use thereof |
| US5334596A (en) * | 1993-05-11 | 1994-08-02 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
| DE4324580A1 (de) * | 1993-07-22 | 1995-01-26 | Thomae Gmbh Dr K | Bicyclische Heterocyclen, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung |
| US5696112A (en) * | 1995-01-17 | 1997-12-09 | American Cyanamid Company | Fused heterocyclic azepines as vasopressin antagonists |
| FR2733750B1 (fr) * | 1995-05-03 | 1997-06-13 | Synthelabo | Derives de l'acide gamma-oxo-alpha-(phenylmethyl)-5,6- dihydro-4h-thieno(3,4-c)pyrrole-5-butanoique, leur preparation et leur application en therapeutique |
| US5939417A (en) * | 1998-10-19 | 1999-08-17 | Cell Pathways Inc | 1,3,6-trihydro-6-aza-3-oxapentalen-2-one derivatives for the treatment of neoplasia |
| RU2485125C2 (ru) * | 2004-06-30 | 2013-06-20 | Эсерсис, Инк. | ЗАМЕЩЕННЫЕ ПРОИЗВОДНЫЕ АЗЕПИНА, ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ И СПОСОБ ЛЕЧЕНИЯ ЗАБОЛЕВАНИЙ, РАССТРОЙСТВ И/ИЛИ ПАТОЛОГИЧЕСКИХ СОСТОЯНИЙ, ПРИ КОТОРЫХ ЖЕЛАТЕЛЬНО МОДУЛИРОВАНИЕ ФУНКЦИИ 5HT2c-РЕЦЕПТОРОВ |
| DK1796663T3 (da) * | 2004-09-03 | 2011-08-15 | Athersys Inc | Tricykliske heteroaryl-piperaziner, pyrrolidiner og azetidiner som serotonin-receptor-modulatorer |
| CA2636992C (en) | 2006-01-19 | 2015-10-06 | Athersys, Inc. | Thiophenyl and pyrrolyl azepines as serotonin 5-ht2c receptor ligands and uses thereof |
| SG11201504749TA (en) | 2012-12-21 | 2015-07-30 | Abt Holding Co | Benzazepines as serotonin 5-ht2c receptor ligands and uses thereof |
| WO2014159067A1 (en) | 2013-03-13 | 2014-10-02 | Abt Holding Company | Thienylindole azepines as serotonin 5-ht2c receptor ligands and uses thereof |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3849441A (en) * | 1971-10-01 | 1974-11-19 | American Cyanamid Co | Substituted heterocyclic derivatives of azepine |
| US3846446A (en) * | 1971-10-01 | 1974-11-05 | American Cyanamid Co | Substituted heterocyclic derivatives of azepine |
| US3758501A (en) * | 1971-10-01 | 1973-09-11 | M Weiss | Substituted heterocyclic derivatives of azepine |
-
1981
- 1981-02-17 ZA ZA821020A patent/ZA821020B/xx unknown
- 1981-02-18 DE DE19813105858 patent/DE3105858A1/de not_active Withdrawn
-
1982
- 1982-02-03 AT AT82100745T patent/ATE13298T1/de not_active IP Right Cessation
- 1982-02-03 EP EP82100745A patent/EP0058341B1/de not_active Expired
- 1982-02-03 DE DE8282100745T patent/DE3263462D1/de not_active Expired
- 1982-02-11 SU SU823388045A patent/SU1091858A3/ru active
- 1982-02-12 US US06/348,496 patent/US4414225A/en not_active Expired - Fee Related
- 1982-02-15 GR GR67317A patent/GR76793B/el unknown
- 1982-02-16 DD DD82237445A patent/DD202577A5/de unknown
- 1982-02-16 CA CA000396329A patent/CA1171084A/en not_active Expired
- 1982-02-16 FI FI820509A patent/FI820509L/fi not_active Application Discontinuation
- 1982-02-16 PH PH26951A patent/PH17724A/en unknown
- 1982-02-17 PT PT74447A patent/PT74447B/pt unknown
- 1982-02-17 ES ES509682A patent/ES8304987A1/es not_active Expired
- 1982-02-17 JP JP57024249A patent/JPS57150687A/ja active Pending
- 1982-02-17 YU YU00349/82A patent/YU34982A/xx unknown
- 1982-02-17 AU AU80552/82A patent/AU547951B2/en not_active Ceased
- 1982-02-17 IE IE338/82A patent/IE52540B1/en unknown
- 1982-02-17 DK DK069382A patent/DK150157C/da not_active IP Right Cessation
- 1982-02-17 GB GB8204585A patent/GB2093030B/en not_active Expired
- 1982-02-17 PL PL1982235121A patent/PL137354B1/pl unknown
- 1982-02-17 NO NO820493A patent/NO157503C/no unknown
- 1982-02-17 NZ NZ199759A patent/NZ199759A/xx unknown
- 1982-02-18 HU HU82499A patent/HU190984B/hu unknown
- 1982-02-18 AR AR288469A patent/AR231983A1/es active
- 1982-02-18 IL IL65051A patent/IL65051A/xx unknown
- 1982-02-18 CS CS821126A patent/CS227039B2/cs unknown
- 1982-09-15 ES ES515730A patent/ES8306755A1/es not_active Expired
- 1982-09-15 ES ES515729A patent/ES515729A0/es active Granted
- 1982-09-15 ES ES515728A patent/ES515728A0/es active Granted
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE3174472D1 (en) | Cephalosporin derivatives, their preparation and compositions containing them | |
| IL75326A0 (en) | Quinolone derivatives and pharmaceutical compositions containing them | |
| IL72566A (en) | Androst-5-en-17-one and 5alpha-androstan-17-one derivatives and pharmaceutical compositions containing the same | |
| PH17724A (en) | Azepine derivatives and their anti-thrombotic compositions and methods | |
| NZ211031A (en) | 6-substituted-4-dialkylaminotetrahindole derivatives and pharmaceutical compositions | |
| NZ201520A (en) | Substituted aminopyridazines and pharmaceutical compositions | |
| NZ211136A (en) | Quinolone derivatives and antibacterial compositions containing such | |
| NZ201833A (en) | Thieno-and furopyridinium-substituted cephalosporin derivatives and pharmaceutical compositions | |
| NZ209064A (en) | N 6 -diarylalkyl-adenosine derivatives and pharmaceutical compositions | |
| GB2110533B (en) | Compositions containing alkaloid derivatives | |
| EP0080442A3 (en) | Di-galactose derivatives and their preparation | |
| IL73508A0 (en) | Milbemycin 5-carbonate derivatives and compositions containing the same | |
| NZ210671A (en) | Ortho-condensed pyrrole derivatives and pharmaceutical compositions | |
| NZ210818A (en) | 8-alpha-acylaminoergoline derivatives and pharmaceutical compositions | |
| NZ211872A (en) | Chartreusin derivatives and antitumorous compositions | |
| NZ208694A (en) | Rooperol derivatives and pharmaceutical compositions | |
| JPS57176980A (en) | Tricyclic compound derivative and manufacture | |
| PH19575A (en) | Cephalosporing derivatives and pharmaceutical compositions thereof | |
| NZ211773A (en) | Tricyclic imidazole derivatives and pharmaceutical compositions | |
| GB2079285B (en) | Dipthosphonate derivatives and pahrmaceutical compositions containing them | |
| PH17494A (en) | New ergoline derivatives and pharmaceutical compositions thereof | |
| GB2067560B (en) | 1-phenyl-4-morpholino-1-buten-3-ol derivatives their preparation and compositions containing them | |
| NZ207806A (en) | Benzothienyl-cephalosporin derivatives and pharmaceutical compositions | |
| NZ210817A (en) | N-hydroxy-alkoxynaphthalinalkanamine derivatives and pharmaceutical compositions | |
| NZ195943A (en) | Rifamycin derivatives and pharmaceutical compositions |