NO820493L - Analogifremgangsmaate for fremstilling av farmakologisk aktive azepinderivater - Google Patents

Analogifremgangsmaate for fremstilling av farmakologisk aktive azepinderivater

Info

Publication number
NO820493L
NO820493L NO820493A NO820493A NO820493L NO 820493 L NO820493 L NO 820493L NO 820493 A NO820493 A NO 820493A NO 820493 A NO820493 A NO 820493A NO 820493 L NO820493 L NO 820493L
Authority
NO
Norway
Prior art keywords
preparation
pharmacologically active
azepine derivatives
analogy procedure
active azepine
Prior art date
Application number
NO820493A
Other languages
English (en)
Other versions
NO157503C (no
NO157503B (no
Inventor
Robert Sauter
Gerhart Griss
Wolfgang Grell
Rudolf Hurnaus
Bernhard Eisele
Walter Haarmann
Eckhard Rupprecht
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of NO820493L publication Critical patent/NO820493L/no
Publication of NO157503B publication Critical patent/NO157503B/no
Publication of NO157503C publication Critical patent/NO157503C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/02Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D223/06Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO820493A 1981-02-18 1982-02-17 Analogifremgangsmaate for fremstilling av farmakologisk aktive azepinderivater. NO157503C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19813105858 DE3105858A1 (de) 1981-02-18 1981-02-18 "neue thieno-azepine, ihre herstellung und ihre verwendung als arzneimittel"

Publications (3)

Publication Number Publication Date
NO820493L true NO820493L (no) 1982-08-19
NO157503B NO157503B (no) 1987-12-21
NO157503C NO157503C (no) 1988-03-30

Family

ID=6125118

Family Applications (1)

Application Number Title Priority Date Filing Date
NO820493A NO157503C (no) 1981-02-18 1982-02-17 Analogifremgangsmaate for fremstilling av farmakologisk aktive azepinderivater.

Country Status (26)

Country Link
US (1) US4414225A (no)
EP (1) EP0058341B1 (no)
JP (1) JPS57150687A (no)
AR (1) AR231983A1 (no)
AT (1) ATE13298T1 (no)
AU (1) AU547951B2 (no)
CA (1) CA1171084A (no)
CS (1) CS227039B2 (no)
DD (1) DD202577A5 (no)
DE (2) DE3105858A1 (no)
DK (1) DK150157C (no)
ES (4) ES509682A0 (no)
FI (1) FI820509L (no)
GB (1) GB2093030B (no)
GR (1) GR76793B (no)
HU (1) HU190984B (no)
IE (1) IE52540B1 (no)
IL (1) IL65051A (no)
NO (1) NO157503C (no)
NZ (1) NZ199759A (no)
PH (1) PH17724A (no)
PL (1) PL137354B1 (no)
PT (1) PT74447B (no)
SU (1) SU1091858A3 (no)
YU (1) YU34982A (no)
ZA (1) ZA821020B (no)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4520025A (en) * 1982-07-21 1985-05-28 William H. Rorer, Inc. Bicyclic nitrogen heterocyclic ethers and thioethers, and their pharmaceutical uses
DE3230696A1 (de) * 1982-08-18 1984-02-23 Dr. Karl Thomae Gmbh, 7950 Biberach Neue thieno-thiazol-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
GB8800891D0 (en) * 1988-01-15 1988-02-17 Lilly Industries Ltd Pharmaceutical compounds
GB8909132D0 (en) * 1989-04-21 1989-06-07 Lilly Industries Ltd Pharmaceutical compounds
FR2652579B1 (fr) * 1989-10-02 1992-01-24 Sanofi Sa Derives d'hydroxy-2 thiophene et furanne condenses avec un cycle azote, sur procede de preparation et leur application en therapeutique.
GB9025890D0 (en) * 1990-11-28 1991-01-09 Lilly Industries Ltd Pharmaceutical compounds
CA2104371A1 (en) * 1991-12-26 1993-06-27 Tohru Nakao Condensed thiophene compound and pharmaceutical use thereof
US5532240A (en) * 1991-12-26 1996-07-02 Yoshitomi Pharmaceutical Industries, Ltd. Condensed thiophene compound and pharmaceutical use thereof
US5334596A (en) * 1993-05-11 1994-08-02 Merck & Co., Inc. Fibrinogen receptor antagonists
DE4324580A1 (de) * 1993-07-22 1995-01-26 Thomae Gmbh Dr K Bicyclische Heterocyclen, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
US5696112A (en) * 1995-01-17 1997-12-09 American Cyanamid Company Fused heterocyclic azepines as vasopressin antagonists
FR2733750B1 (fr) * 1995-05-03 1997-06-13 Synthelabo Derives de l'acide gamma-oxo-alpha-(phenylmethyl)-5,6- dihydro-4h-thieno(3,4-c)pyrrole-5-butanoique, leur preparation et leur application en therapeutique
US5939417A (en) * 1998-10-19 1999-08-17 Cell Pathways Inc 1,3,6-trihydro-6-aza-3-oxapentalen-2-one derivatives for the treatment of neoplasia
ES2398694T3 (es) * 2004-06-30 2013-03-21 Athersys, Inc. Derivados de azepina sustituidos como moduladores de receptores de serotonina
US7423056B2 (en) 2004-09-03 2008-09-09 Athersys, Inc. Tricyclic heteroaryl piperazines, pyrrolidines and azetidines as serotonin receptor modulators
MX2008009178A (es) 2006-01-19 2008-12-05 Athersys Inc Tiofenil y pirrolil acepinas como ligandos del receptor de serotonina 5-ht2c y sus usos.
SG11201504749TA (en) 2012-12-21 2015-07-30 Abt Holding Co Benzazepines as serotonin 5-ht2c receptor ligands and uses thereof
US9309262B2 (en) 2013-03-13 2016-04-12 Abt Holding Company Thienylindole azepines as serotonin 5-HT2C receptor ligands and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3849441A (en) * 1971-10-01 1974-11-19 American Cyanamid Co Substituted heterocyclic derivatives of azepine
US3758501A (en) * 1971-10-01 1973-09-11 M Weiss Substituted heterocyclic derivatives of azepine
US3846446A (en) * 1971-10-01 1974-11-05 American Cyanamid Co Substituted heterocyclic derivatives of azepine

Also Published As

Publication number Publication date
AU8055282A (en) 1982-08-26
AU547951B2 (en) 1985-11-14
ES8306754A1 (es) 1983-06-01
CS227039B2 (en) 1984-04-16
SU1091858A3 (ru) 1984-05-07
AR231983A1 (es) 1985-04-30
DK69382A (da) 1982-08-19
ES8304987A1 (es) 1983-03-16
ZA821020B (en) 1983-10-26
US4414225A (en) 1983-11-08
PT74447A (de) 1982-03-01
DK150157B (da) 1986-12-22
NO157503C (no) 1988-03-30
NZ199759A (en) 1985-09-13
EP0058341B1 (de) 1985-05-15
CA1171084A (en) 1984-07-17
ES8306753A1 (es) 1983-06-01
IE820338L (en) 1982-08-18
ATE13298T1 (de) 1985-06-15
HU190984B (en) 1986-12-28
ES515729A0 (es) 1983-06-01
HUT34754A (en) 1985-04-28
YU34982A (en) 1985-04-30
DD202577A5 (de) 1983-09-21
FI820509L (fi) 1982-08-19
DK150157C (da) 1987-06-29
NO157503B (no) 1987-12-21
EP0058341A1 (de) 1982-08-25
PH17724A (en) 1984-11-21
GR76793B (no) 1984-09-04
ES509682A0 (es) 1983-03-16
PL137354B1 (en) 1986-05-31
ES515728A0 (es) 1983-06-01
ES515730A0 (es) 1983-06-01
GB2093030A (en) 1982-08-25
PT74447B (de) 1984-10-09
GB2093030B (en) 1985-01-16
PL235121A1 (no) 1982-10-25
IL65051A0 (en) 1982-04-30
IE52540B1 (en) 1987-12-09
DE3105858A1 (de) 1982-09-02
ES8306755A1 (es) 1983-06-01
JPS57150687A (en) 1982-09-17
IL65051A (en) 1986-11-30
DE3263462D1 (en) 1985-06-20

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