SMT201800551T1 - Inibitori di jak1 per il trattamento di sindromi mielodisplastiche - Google Patents

Inibitori di jak1 per il trattamento di sindromi mielodisplastiche

Info

Publication number
SMT201800551T1
SMT201800551T1 SM20180551T SMT201800551T SMT201800551T1 SM T201800551 T1 SMT201800551 T1 SM T201800551T1 SM 20180551 T SM20180551 T SM 20180551T SM T201800551 T SMT201800551 T SM T201800551T SM T201800551 T1 SMT201800551 T1 SM T201800551T1
Authority
SM
San Marino
Prior art keywords
treatment
myelodysplastic syndromes
jak1 inhibitors
jak1
inhibitors
Prior art date
Application number
SM20180551T
Other languages
English (en)
Italian (it)
Inventor
Krishna Vaddi
Original Assignee
Incyte Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Corp filed Critical Incyte Corp
Publication of SMT201800551T1 publication Critical patent/SMT201800551T1/it

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965Non-condensed pyrazines
    • A61K31/497Non-condensed pyrazines containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SM20180551T 2014-02-28 2015-02-27 Inibitori di jak1 per il trattamento di sindromi mielodisplastiche SMT201800551T1 (it)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461946124P 2014-02-28 2014-02-28
EP15710994.3A EP3110409B1 (en) 2014-02-28 2015-02-27 Jak1 inhibitors for the treatment of myelodysplastic syndromes
PCT/US2015/017963 WO2015131031A1 (en) 2014-02-28 2015-02-27 Jak1 inhibitors for the treatment of myelodysplastic syndromes

Publications (1)

Publication Number Publication Date
SMT201800551T1 true SMT201800551T1 (it) 2019-01-11

Family

ID=52693052

Family Applications (1)

Application Number Title Priority Date Filing Date
SM20180551T SMT201800551T1 (it) 2014-02-28 2015-02-27 Inibitori di jak1 per il trattamento di sindromi mielodisplastiche

Country Status (29)

Country Link
US (4) US20150246046A1 (enExample)
EP (1) EP3110409B1 (enExample)
JP (1) JP6576941B2 (enExample)
KR (1) KR20160136323A (enExample)
CN (2) CN112494652A (enExample)
AU (1) AU2015222913B2 (enExample)
CA (1) CA2940659C (enExample)
CL (1) CL2016002144A1 (enExample)
CR (1) CR20160449A (enExample)
CY (1) CY1120857T1 (enExample)
DK (1) DK3110409T3 (enExample)
EA (1) EA201691745A1 (enExample)
ES (1) ES2688553T3 (enExample)
HR (1) HRP20181661T1 (enExample)
HU (1) HUE041456T2 (enExample)
IL (1) IL247475B (enExample)
LT (1) LT3110409T (enExample)
MX (1) MX372939B (enExample)
MY (1) MY185392A (enExample)
PE (1) PE20161388A1 (enExample)
PL (1) PL3110409T3 (enExample)
PT (1) PT3110409T (enExample)
RS (1) RS57723B1 (enExample)
SG (2) SG11201607083VA (enExample)
SI (1) SI3110409T1 (enExample)
SM (1) SMT201800551T1 (enExample)
UA (1) UA121857C2 (enExample)
WO (1) WO2015131031A1 (enExample)
ZA (1) ZA201606610B (enExample)

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KR101934107B1 (ko) * 2016-12-15 2018-12-31 가톨릭대학교산학협력단 골수형성이상 증후군 환자의 저메틸화 제제 치료 반응성 및 생존 예후 예측용 조성물
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CN109867676B (zh) * 2017-12-01 2020-10-30 北京普祺医药科技有限公司 一种吡咯并嘧啶衍生的化合物、药物组合物以及其用途
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Also Published As

Publication number Publication date
EP3110409B1 (en) 2018-08-15
US20150246046A1 (en) 2015-09-03
MX372939B (es) 2020-04-03
LT3110409T (lt) 2019-01-25
HRP20181661T1 (hr) 2018-12-14
MX2016011103A (es) 2017-02-28
EA201691745A1 (ru) 2016-12-30
CY1120857T1 (el) 2019-12-11
IL247475B (en) 2020-05-31
ES2688553T3 (es) 2018-11-05
ZA201606610B (en) 2020-08-26
WO2015131031A1 (en) 2015-09-03
AU2015222913B2 (en) 2019-12-12
DK3110409T3 (en) 2018-10-22
CA2940659C (en) 2023-01-03
PT3110409T (pt) 2018-11-07
EP3110409A1 (en) 2017-01-04
HUE041456T2 (hu) 2019-05-28
CL2016002144A1 (es) 2016-12-16
JP2017506659A (ja) 2017-03-09
NZ724464A (en) 2021-01-29
CN112494652A (zh) 2021-03-16
SG10201807952PA (en) 2018-10-30
CR20160449A (es) 2016-12-20
MY185392A (en) 2021-05-17
PL3110409T3 (pl) 2018-12-31
BR112016019511A8 (pt) 2023-01-24
AU2015222913A1 (en) 2016-09-29
US20190111058A1 (en) 2019-04-18
SI3110409T1 (sl) 2018-11-30
US20220378791A1 (en) 2022-12-01
RS57723B1 (sr) 2018-12-31
JP6576941B2 (ja) 2019-09-18
SG11201607083VA (en) 2016-09-29
CA2940659A1 (en) 2015-09-03
IL247475A0 (en) 2016-11-30
UA121857C2 (uk) 2020-08-10
BR112016019511A2 (enExample) 2017-08-15
KR20160136323A (ko) 2016-11-29
US20210069193A1 (en) 2021-03-11
PE20161388A1 (es) 2016-12-28
CN106456773A (zh) 2017-02-22

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