CN112494652A - 用于治疗骨髓增生异常综合征的jak1抑制剂 - Google Patents
用于治疗骨髓增生异常综合征的jak1抑制剂 Download PDFInfo
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- CN112494652A CN112494652A CN202010986614.7A CN202010986614A CN112494652A CN 112494652 A CN112494652 A CN 112494652A CN 202010986614 A CN202010986614 A CN 202010986614A CN 112494652 A CN112494652 A CN 112494652A
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- pyrimidin
- pyrrolo
- pyrazol
- trifluoromethyl
- acetonitrile
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| ATE525374T1 (de) | 2005-12-13 | 2011-10-15 | Incyte Corp | Heteroarylsubstituierte pyrroloä2,3-büpyridine und pyrroloä2,3-büpyrimidine als januskinaseinhibitoren |
| ES2467665T5 (es) | 2007-06-13 | 2022-11-03 | Incyte Holdings Corp | Sales del inhibidor de cinasas Janus (R)-3-(4-(7H-pirrolo[2,3-d]pirimidin-4-il)-1H-pirazol-1-il)-3-ciclopentilpropanonitrilo |
| JP6172939B2 (ja) | 2009-05-22 | 2017-08-02 | インサイト・ホールディングス・コーポレイションＩｎｃｙｔｅ Ｈｏｌｄｉｎｇｓ Ｃｏｒｐｏｒａｔｉｏｎ | Ｊａｋ阻害薬としての３−［４−（７ｈ−ピロロ［２，３−ｄ］ピリミジン−４−イル）−１ｈ−ピラゾール−１−イル］オクタン−またはヘプタン−ニトリル |
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| KR102303885B1 (ko) | 2010-05-21 | 2021-09-24 | 인사이트 홀딩스 코포레이션 | Ｊａｋ 저해제에 대한 국소 제형 |
| EA026201B1 (ru) | 2010-11-19 | 2017-03-31 | Инсайт Холдингс Корпорейшн | Циклобутилзамещенные производные пирролопиридина и пирролопиримидина как ингибиторы jak |
| CA2839767A1 (en) | 2011-06-20 | 2012-12-27 | Incyte Corporation | Azetidinyl phenyl, pyridyl or pyrazinyl carboxamide derivatives as jak inhibitors |
| UA111854C2 (uk) | 2011-09-07 | 2016-06-24 | Інсайт Холдінгс Корпорейшн | Способи і проміжні сполуки для отримання інгібіторів jak |
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| MY185686A (en) | 2014-04-08 | 2021-05-30 | Incyte Corp | Treatment of b-cell malignancies by a combination jak and p13k inhibitor |
| MA39987A (fr) | 2014-04-30 | 2017-03-08 | Incyte Corp | Procédés de préparation d'un inhibiteur de jak1 et nouvelles formes associées |
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| WO2016010897A1 (en) | 2014-07-14 | 2016-01-21 | Incyte Corporation | Bicyclic heteroaromatic carboxamide compounds useful as pim kinase inhibitors |
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2015
- 2015-02-27 HR HRP20181661TT patent/HRP20181661T1/hr unknown
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- 2015-02-27 KR KR1020167026668A patent/KR20160136323A/ko not_active Ceased
- 2015-02-27 US US14/633,605 patent/US20150246046A1/en not_active Abandoned
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- 2015-02-27 PL PL15710994T patent/PL3110409T3/pl unknown
- 2015-02-27 SM SM20180551T patent/SMT201800551T1/it unknown
- 2015-02-27 CA CA2940659A patent/CA2940659C/en active Active
- 2015-02-27 CN CN202010986614.7A patent/CN112494652A/zh active Pending
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- 2015-02-27 CN CN201580017178.XA patent/CN106456773A/zh active Pending
- 2015-02-27 DK DK15710994.3T patent/DK3110409T3/en active
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- 2015-02-27 LT LTEP15710994.3T patent/LT3110409T/lt unknown
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- 2015-02-27 SG SG10201807952PA patent/SG10201807952PA/en unknown
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2018
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2020
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