SMT201500104B - Trattamento della leucemia linfoblastica acuta in eta'pediatrica - Google Patents

Trattamento della leucemia linfoblastica acuta in eta'pediatrica

Info

Publication number
SMT201500104B
SMT201500104B SM201500104T SM201500104T SMT201500104B SM T201500104 B SMT201500104 B SM T201500104B SM 201500104 T SM201500104 T SM 201500104T SM 201500104 T SM201500104 T SM 201500104T SM T201500104 B SMT201500104 B SM T201500104B
Authority
SM
San Marino
Prior art keywords
children
treatment
lymphoblastic leukemia
acute lymphoblastic
acute
Prior art date
Application number
SM201500104T
Other languages
English (en)
Italian (it)
Inventor
Gerhard Zugmaier
Original Assignee
Amgen Res Munich Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Res Munich Gmbh filed Critical Amgen Res Munich Gmbh
Publication of SMT201500104B publication Critical patent/SMT201500104B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3061—Blood cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
SM201500104T 2008-11-07 2015-04-27 Trattamento della leucemia linfoblastica acuta in eta'pediatrica SMT201500104B (it)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US11232308P 2008-11-07 2008-11-07
US18329109P 2009-06-02 2009-06-02
US22126909P 2009-06-29 2009-06-29
PCT/EP2009/007969 WO2010052013A1 (en) 2008-11-07 2009-11-06 Treatment of pediatric acute lymphoblastic leukemia

Publications (1)

Publication Number Publication Date
SMT201500104B true SMT201500104B (it) 2015-07-09

Family

ID=41796119

Family Applications (1)

Application Number Title Priority Date Filing Date
SM201500104T SMT201500104B (it) 2008-11-07 2015-04-27 Trattamento della leucemia linfoblastica acuta in eta'pediatrica

Country Status (27)

Country Link
US (2) US20110262440A1 (ja)
EP (4) EP3330293B1 (ja)
JP (2) JP5798036B2 (ja)
KR (1) KR101695329B1 (ja)
CN (2) CN102209729B (ja)
AU (1) AU2009313039B2 (ja)
BR (1) BRPI0921341A2 (ja)
CA (1) CA2742242C (ja)
CY (3) CY1116160T1 (ja)
DK (3) DK2918604T3 (ja)
ES (3) ES2748126T3 (ja)
HK (3) HK1158667A1 (ja)
HR (3) HRP20150400T1 (ja)
HU (3) HUE046222T2 (ja)
IL (1) IL212651A (ja)
LT (2) LT3330293T (ja)
MX (1) MX2011002931A (ja)
NO (1) NO2918604T3 (ja)
NZ (1) NZ591312A (ja)
PL (3) PL3330293T3 (ja)
PT (3) PT2344539E (ja)
RS (3) RS56989B1 (ja)
RU (3) RU2536933C2 (ja)
SG (1) SG195549A1 (ja)
SI (3) SI2918604T1 (ja)
SM (1) SMT201500104B (ja)
WO (1) WO2010052013A1 (ja)

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KR20240033145A (ko) * 2012-11-13 2024-03-12 비온테크 에스이 클라우딘 발현 암 질환의 치료제
TWI682941B (zh) 2013-02-01 2020-01-21 美商再生元醫藥公司 含嵌合恆定區之抗體
CN103131777A (zh) * 2013-02-05 2013-06-05 南京艾迪康医学检验所有限公司 用于检测e2a-pbx融合基因相对表达量的试剂盒
EP3105252B1 (en) 2014-02-12 2019-07-24 Michael Uhlin Bispecific antibodies for use in stem cell transplantation
TWI701042B (zh) 2014-03-19 2020-08-11 美商再生元醫藥公司 用於腫瘤治療之方法及抗體組成物
HUE042407T2 (hu) 2014-05-30 2019-06-28 Amgen Res Munich Gmbh B-prekurzor akut limfoblasztos leukémiában szenvedõ betegek kockázati besorolása
WO2016016898A1 (en) 2014-07-30 2016-02-04 Smadar Avigad Compositions for treatment of acute lymphoblastic leukemia and methods of use thereof
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ES2846748T3 (es) 2015-03-30 2021-07-29 Regeneron Pharma Regiones constantes de cadenas pesadas con unión reducida a receptores Fc gamma
IL303972A (en) 2015-04-08 2023-08-01 Novartis Ag CD20 treatments, CD22 treatments and combined treatments with CD19 chimeric antigen receptor expressing cell
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WO2017112762A1 (en) * 2015-12-22 2017-06-29 Regeneron Pharmaceuticals, Inc. Bispecific anti-cd20/anti-cd3 antibodies to treat acute lymphoblastic leukemia
GB201602974D0 (en) * 2016-02-19 2016-04-06 Clube Jasper R Engineered cells & methods (1)
MA45341A (fr) * 2016-06-06 2019-04-10 Hutchinson Fred Cancer Res Procédés de traitement de malignités de lymphocytes b au moyen d'une thérapie cellulaire adoptive
CA3045339A1 (en) 2016-12-03 2018-06-07 Juno Therapeutics, Inc. Methods and compositions for use of therapeutic t cells in combination with kinase inhibitors
BR112019022751A2 (pt) * 2017-05-05 2020-05-19 Amgen Inc composição farmacêutica compreendendo construtos de anticorpos biespecíficos para armazenamento e administração melhorados
AU2018275894A1 (en) 2017-06-02 2019-12-12 Juno Therapeutics, Inc. Articles of manufacture and methods for treatment using adoptive cell therapy
US12031975B2 (en) 2017-11-01 2024-07-09 Juno Therapeutics, Inc. Methods of assessing or monitoring a response to a cell therapy
KR102083481B1 (ko) 2018-03-22 2020-03-02 강원대학교산학협력단 아연-키토산 나노 입자를 포함한 급성 림프구성 백혈병 치료용 약학조성물
CN112771077A (zh) 2018-08-31 2021-05-07 瑞泽恩制药公司 针对cd3/c20双特异性抗体的减轻细胞因子释放综合征的给药策略
BR112021014255A2 (pt) * 2019-01-30 2022-01-18 Wistar Inst Molécula de ácido nucleico, composição, e, método de prevenção ou tratamento de uma doença ou distúrbio
JP7137696B2 (ja) 2019-05-14 2022-09-14 プロヴェンション・バイオ・インコーポレイテッド １型糖尿病を予防するための方法および組成物
US20220372148A1 (en) 2019-07-05 2022-11-24 Ono Pharmaceutical Co., Ltd. A pharmaceutical composition for treating hematological cancer
CA3182445A1 (en) 2020-06-11 2021-12-16 Francisco Leon Methods and compositions for preventing type 1 diabetes
EP4415829A1 (en) 2021-10-15 2024-08-21 Amgen Research (Munich) GmbH Subcutaneous administration of cd19-binding t cell engaging antibodies

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Also Published As

Publication number Publication date
EP3330293B1 (en) 2019-07-24
US20110262440A1 (en) 2011-10-27
KR101695329B1 (ko) 2017-01-23
NZ591312A (en) 2012-09-28
SI2918604T1 (en) 2018-04-30
EP2918604B1 (en) 2017-12-20
EP3594237A1 (en) 2020-01-15
SI2344539T1 (sl) 2015-06-30
RU2014141180A (ru) 2016-05-10
HK1158667A1 (en) 2012-07-20
JP2012508163A (ja) 2012-04-05
US20230235053A1 (en) 2023-07-27
WO2010052013A1 (en) 2010-05-14
DK2344539T3 (en) 2015-05-04
JP5798036B2 (ja) 2015-10-21
HK1255590B (zh) 2020-07-10
RU2677324C2 (ru) 2019-01-16
CN102209729A (zh) 2011-10-05
CA2742242C (en) 2023-01-10
MX2011002931A (es) 2011-04-11
LT3330293T (lt) 2019-10-10
HRP20180426T1 (hr) 2018-04-20
SG195549A1 (en) 2013-12-30
RU2011122827A (ru) 2012-12-20
JP2015232023A (ja) 2015-12-24
EP3330293A1 (en) 2018-06-06
ES2662929T3 (es) 2018-04-10
CA2742242A1 (en) 2010-05-14
JP6130451B2 (ja) 2017-05-17
NO2918604T3 (ja) 2018-05-19
RU2736802C2 (ru) 2020-11-20
PL2344539T3 (pl) 2015-07-31
BRPI0921341A2 (pt) 2016-04-26
AU2009313039B2 (en) 2015-06-18
IL212651A0 (en) 2011-07-31
HK1215258A1 (zh) 2016-08-19
IL212651A (en) 2015-03-31
HUE036922T2 (hu) 2018-08-28
ES2535257T3 (es) 2015-05-07
RS56989B1 (sr) 2018-05-31
CY1120022T1 (el) 2018-12-12
RU2014141180A3 (ja) 2018-06-09
EP2918604A1 (en) 2015-09-16
HRP20150400T1 (hr) 2015-05-08
RU2536933C2 (ru) 2014-12-27
RU2018144313A (ru) 2020-06-15
LT2918604T (lt) 2018-03-26
ES2748126T3 (es) 2020-03-13
EP2344539B1 (en) 2015-02-11
PT3330293T (pt) 2019-10-18
SI3330293T1 (sl) 2019-10-30
AU2009313039A1 (en) 2010-05-14
CN102209729B (zh) 2016-05-25
RU2018144313A3 (ja) 2020-06-15
CY1116160T1 (el) 2017-02-08
CY1122428T1 (el) 2021-01-27
HRP20191715T1 (hr) 2019-12-13
HUE046222T2 (hu) 2020-02-28
PT2344539E (pt) 2015-04-01
EP2344539A1 (en) 2011-07-20
DK3330293T3 (da) 2019-10-07
PT2918604T (pt) 2018-03-02
DK2918604T3 (en) 2018-03-19
RS53980B1 (en) 2015-10-30
PL2918604T3 (pl) 2018-05-30
KR20110091669A (ko) 2011-08-12
HUE025452T2 (en) 2016-05-30
PL3330293T3 (pl) 2020-02-28
RS59348B1 (sr) 2019-10-31
CN106390114A (zh) 2017-02-15

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