NO2918604T3 - - Google Patents

Info

Publication number
NO2918604T3
NO2918604T3 NO15154416A NO15154416A NO2918604T3 NO 2918604 T3 NO2918604 T3 NO 2918604T3 NO 15154416 A NO15154416 A NO 15154416A NO 15154416 A NO15154416 A NO 15154416A NO 2918604 T3 NO2918604 T3 NO 2918604T3
Authority
NO
Norway
Application number
NO15154416A
Other languages
Norwegian (no)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of NO2918604T3 publication Critical patent/NO2918604T3/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3061—Blood cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
NO15154416A 2008-11-07 2009-11-06 NO2918604T3 (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US11232308P 2008-11-07 2008-11-07
US18329109P 2009-06-02 2009-06-02
US22126909P 2009-06-29 2009-06-29
EP09764710.1A EP2344539B1 (en) 2008-11-07 2009-11-06 Treatment of pediatric acute lymphoblastic leukemia

Publications (1)

Publication Number Publication Date
NO2918604T3 true NO2918604T3 (ja) 2018-05-19

Family

ID=41796119

Family Applications (1)

Application Number Title Priority Date Filing Date
NO15154416A NO2918604T3 (ja) 2008-11-07 2009-11-06

Country Status (27)

Country Link
US (2) US20110262440A1 (ja)
EP (4) EP2344539B1 (ja)
JP (2) JP5798036B2 (ja)
KR (1) KR101695329B1 (ja)
CN (2) CN102209729B (ja)
AU (1) AU2009313039B2 (ja)
BR (1) BRPI0921341A2 (ja)
CA (1) CA2742242C (ja)
CY (3) CY1116160T1 (ja)
DK (3) DK3330293T3 (ja)
ES (3) ES2535257T3 (ja)
HK (3) HK1158667A1 (ja)
HR (3) HRP20150400T1 (ja)
HU (3) HUE036922T2 (ja)
IL (1) IL212651A (ja)
LT (2) LT3330293T (ja)
MX (1) MX2011002931A (ja)
NO (1) NO2918604T3 (ja)
NZ (1) NZ591312A (ja)
PL (3) PL3330293T3 (ja)
PT (3) PT2344539E (ja)
RS (3) RS53980B1 (ja)
RU (3) RU2536933C2 (ja)
SG (1) SG195549A1 (ja)
SI (3) SI2344539T1 (ja)
SM (1) SMT201500104B (ja)
WO (1) WO2010052013A1 (ja)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6358588A (ja) * 1986-08-29 1988-03-14 Toshiba Corp バ−コ−ド読取装置
DE10254601A1 (de) 2002-11-22 2004-06-03 Ganymed Pharmaceuticals Ag Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung
KR101695329B1 (ko) * 2008-11-07 2017-01-23 암젠 리서치 (뮌헨) 게엠베하 소아 급성 림프구성 백혈병의 치료방법
ES2565439T3 (es) * 2009-01-09 2016-04-04 Oxford Biomedica (Uk) Ltd Factores
US20150231241A1 (en) * 2012-08-14 2015-08-20 Ibc Pharmaceuticals, Inc. Combination therapy for inducing immune response to disease
JOP20200236A1 (ar) 2012-09-21 2017-06-16 Regeneron Pharma الأجسام المضادة لمضاد cd3 وجزيئات ربط الأنتيجين ثنائية التحديد التي تربط cd3 وcd20 واستخداماتها
JP6499079B2 (ja) 2012-11-13 2019-04-10 バイオエヌテック アーゲーＢｉｏＮＴｅｃｈ ＡＧ クローディンを発現するガン疾患を処置するための剤
TWI682941B (zh) 2013-02-01 2020-01-21 美商再生元醫藥公司 含嵌合恆定區之抗體
CN103131777A (zh) * 2013-02-05 2013-06-05 南京艾迪康医学检验所有限公司 用于检测e2a-pbx融合基因相对表达量的试剂盒
WO2015121383A1 (en) 2014-02-12 2015-08-20 Michael Uhlin Bispecific antibodies for use in stem cell transplantation
TWI754319B (zh) 2014-03-19 2022-02-01 美商再生元醫藥公司 用於腫瘤治療之方法及抗體組成物
PL3531133T3 (pl) 2014-05-30 2024-01-29 Amgen Research (Munich) Gmbh Stratyfikacja ryzyka u pacjentów z ostrą białaczką limfoblastyczną z prekursorów b
CN107075573A (zh) * 2014-07-30 2017-08-18 莫尔研究应用有限公司 用于急性淋巴细胞白血病的预后方法和治疗系统
US20170239294A1 (en) * 2014-10-15 2017-08-24 Novartis Ag Compositions and methods for treating b-lymphoid malignancies
HUE050831T2 (hu) 2014-11-17 2021-01-28 Regeneron Pharma Daganatkezelési módszerek a CD3XCD20 bispecifikus antitest használatával
WO2016127043A1 (en) * 2015-02-05 2016-08-11 Stc.Unm Anti-pre-bcr antagonists and methods
AU2016242866B2 (en) 2015-03-30 2021-06-03 Regeneron Pharmaceuticals, Inc. Heavy chain constant regions with reduced binding to FC gamma receptors
MX2017012939A (es) 2015-04-08 2018-05-22 Novartis Ag Terapias cd20, terapias cd22 y terapias de combinacion con una celula que expresa un receptor quimerico de antigeno (car) de cd19.
WO2016184931A1 (en) 2015-05-20 2016-11-24 Amgen Research (Munich) Gmbh B-cell depletion as a diagnostic marker
CN108602889A (zh) * 2015-12-22 2018-09-28 瑞泽恩制药公司 医治急性成淋巴细胞性白血病的双特异性抗cd20/抗cd3抗体
GB201602974D0 (en) * 2016-02-19 2016-04-06 Clube Jasper R Engineered cells & methods (1)
MA45341A (fr) * 2016-06-06 2019-04-10 Hutchinson Fred Cancer Res Procédés de traitement de malignités de lymphocytes b au moyen d'une thérapie cellulaire adoptive
US11590167B2 (en) 2016-12-03 2023-02-28 Juno Therapeutic, Inc. Methods and compositions for use of therapeutic T cells in combination with kinase inhibitors
CN110913904A (zh) * 2017-05-05 2020-03-24 美国安进公司 用于改善的储存和施用的包含双特异性抗体构建体的药物组合物
AU2018275894A1 (en) 2017-06-02 2019-12-12 Juno Therapeutics, Inc. Articles of manufacture and methods for treatment using adoptive cell therapy
KR102083481B1 (ko) 2018-03-22 2020-03-02 강원대학교산학협력단 아연-키토산 나노 입자를 포함한 급성 림프구성 백혈병 치료용 약학조성물
AU2019331024A1 (en) 2018-08-31 2021-03-18 Regeneron Pharmaceuticals, Inc. Dosing strategy that mitigates cytokine release syndrome for CD3/C20 bispecific antibodies
WO2020160310A1 (en) * 2019-01-30 2020-08-06 The Wistar Institute Of Anatomy And Biology Dna-encoded bispecific t-cell engagers targeting cancer antigens and methods of use in cancer theraputics
WO2020232247A1 (en) 2019-05-14 2020-11-19 Provention Bio, Inc. Methods and compositions for preventing type 1 diabetes
TWI809286B (zh) 2019-07-05 2023-07-21 日商小野藥品工業股份有限公司 以pd-1/cd3雙特異性蛋白質所進行之血液性癌症治療
CA3235228A1 (en) 2021-10-15 2023-04-20 Amgen Research (Munich) Gmbh Subcutaneous administration of cd19-binding t cell engagers

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998008875A1 (de) * 1996-08-28 1998-03-05 Viva Diagnostika Diagnostische Produkte Gmbh Kombinationspräparationen und ihre verwendung in der immundiagnostik und immuntherapie
WO1999054440A1 (en) * 1998-04-21 1999-10-28 Micromet Gesellschaft Für Biomedizinische Forschung Mbh CD19xCD3 SPECIFIC POLYPEPTIDES AND USES THEREOF
EP1629012B1 (en) 2003-05-31 2018-11-28 Amgen Research (Munich) GmbH Pharmaceutical compositions comprising bispecific anti-cd3, anti-cd19 antibody constructs for the treatment of b-cell related disorders
KR20120125634A (ko) * 2003-10-16 2012-11-16 마이크로메트 에이지 다중특이적 탈면역화된 ｃｄ3-바인더
CA2633594C (en) 2005-12-16 2021-10-26 Micromet Ag Means and methods for the treatment of tumorous diseases
WO2008022152A2 (en) * 2006-08-14 2008-02-21 Xencor, Inc. Optimized antibodies that target cd19
SI2352763T2 (sl) * 2008-10-01 2022-11-30 Amgen Research (Munich) Gmbh Bispecifična enoverižna protitelesa s specifičnostjo za tarčne antigene z visoko molekulsko maso
KR101695329B1 (ko) * 2008-11-07 2017-01-23 암젠 리서치 (뮌헨) 게엠베하 소아 급성 림프구성 백혈병의 치료방법
AU2010204554B2 (en) * 2009-01-19 2013-05-30 Abbvie Inc. Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases
KR20110116161A (ko) * 2009-01-19 2011-10-25 아보트 러보러터리즈 암, 면역 질환 및 자가면역 질환의 치료를 위한 아폽토시스-유도제
US8486933B2 (en) * 2009-05-27 2013-07-16 Abbvie Inc. Pyrimidine inhibitors of kinase activity
WO2011034934A1 (en) * 2009-09-20 2011-03-24 Abbott Laboratories Abt-263 crystalline forms and solvates for use in treating bcl-2 protein related diseases
ME02947B (me) * 2009-10-27 2018-04-20 Amgen Res Munich Gmbh Režim doziranja kod primjene dvojno specifičnog protutijela cd19xcd3

Also Published As

Publication number Publication date
CN102209729A (zh) 2011-10-05
ES2748126T3 (es) 2020-03-13
IL212651A0 (en) 2011-07-31
AU2009313039A1 (en) 2010-05-14
EP2344539B1 (en) 2015-02-11
PT3330293T (pt) 2019-10-18
KR20110091669A (ko) 2011-08-12
JP5798036B2 (ja) 2015-10-21
SMT201500104B (it) 2015-07-09
HK1215258A1 (zh) 2016-08-19
DK3330293T3 (da) 2019-10-07
MX2011002931A (es) 2011-04-11
KR101695329B1 (ko) 2017-01-23
CA2742242A1 (en) 2010-05-14
HUE036922T2 (hu) 2018-08-28
CN102209729B (zh) 2016-05-25
SI2344539T1 (sl) 2015-06-30
CA2742242C (en) 2023-01-10
PL2344539T3 (pl) 2015-07-31
RS56989B1 (sr) 2018-05-31
PL2918604T3 (pl) 2018-05-30
HRP20150400T1 (hr) 2015-05-08
HRP20180426T1 (hr) 2018-04-20
WO2010052013A1 (en) 2010-05-14
EP2918604B1 (en) 2017-12-20
JP2012508163A (ja) 2012-04-05
BRPI0921341A2 (pt) 2016-04-26
EP3330293B1 (en) 2019-07-24
HUE046222T2 (hu) 2020-02-28
DK2344539T3 (en) 2015-05-04
HUE025452T2 (en) 2016-05-30
RU2014141180A3 (ja) 2018-06-09
LT3330293T (lt) 2019-10-10
CN106390114A (zh) 2017-02-15
HK1255590B (zh) 2020-07-10
RU2011122827A (ru) 2012-12-20
RU2014141180A (ru) 2016-05-10
DK2918604T3 (en) 2018-03-19
PL3330293T3 (pl) 2020-02-28
JP6130451B2 (ja) 2017-05-17
RS53980B1 (en) 2015-10-30
SG195549A1 (en) 2013-12-30
PT2344539E (pt) 2015-04-01
RS59348B1 (sr) 2019-10-31
SI2918604T1 (en) 2018-04-30
LT2918604T (lt) 2018-03-26
EP3594237A1 (en) 2020-01-15
CY1122428T1 (el) 2021-01-27
RU2677324C2 (ru) 2019-01-16
ES2535257T3 (es) 2015-05-07
ES2662929T3 (es) 2018-04-10
EP2344539A1 (en) 2011-07-20
EP2918604A1 (en) 2015-09-16
US20110262440A1 (en) 2011-10-27
HRP20191715T1 (hr) 2019-12-13
RU2018144313A (ru) 2020-06-15
JP2015232023A (ja) 2015-12-24
RU2536933C2 (ru) 2014-12-27
RU2018144313A3 (ja) 2020-06-15
CY1120022T1 (el) 2018-12-12
US20230235053A1 (en) 2023-07-27
PT2918604T (pt) 2018-03-02
IL212651A (en) 2015-03-31
AU2009313039B2 (en) 2015-06-18
RU2736802C2 (ru) 2020-11-20
EP3330293A1 (en) 2018-06-06
SI3330293T1 (sl) 2019-10-30
HK1158667A1 (en) 2012-07-20
CY1116160T1 (el) 2017-02-08
NZ591312A (en) 2012-09-28

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