CY1116160T1 - Θεραπεια παιδιατρικης οξειας λεμφοβλαστικης λευχαιμιας - Google Patents

Θεραπεια παιδιατρικης οξειας λεμφοβλαστικης λευχαιμιας

Info

Publication number
CY1116160T1
CY1116160T1 CY20151100317T CY151100317T CY1116160T1 CY 1116160 T1 CY1116160 T1 CY 1116160T1 CY 20151100317 T CY20151100317 T CY 20151100317T CY 151100317 T CY151100317 T CY 151100317T CY 1116160 T1 CY1116160 T1 CY 1116160T1
Authority
CY
Cyprus
Prior art keywords
acute
pediatric
lymphoblastic leukemia
leukemia treatment
acute lymphoblastic
Prior art date
Application number
CY20151100317T
Other languages
English (en)
Inventor
Gerhard Zugmaier
Original Assignee
Amgen Research (Munich) Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Research (Munich) Gmbh filed Critical Amgen Research (Munich) Gmbh
Publication of CY1116160T1 publication Critical patent/CY1116160T1/el

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3061—Blood cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

Η παρούσα εφεύρεση αφορά σε μία μέθοδο για τη θεραπεία, βελτίωση ή ελαχιστοποίηση παιδιατρικής οξείας λεμφοβλαστικής λευχαιμίας (ALL), η δε μέθοδος περιλαμβάνει τη χορήγηση μιας φαρμακευτικής σύνθεσης που περιλαμβάνει κατασκεύασμα CD19xCD3 διπλά ειδικού αλύσου αντισώματος σε έναν παιδιατρικό ALL ασθενή που έχει ανάγκη αυτού.
CY20151100317T 2008-11-07 2015-03-31 Θεραπεια παιδιατρικης οξειας λεμφοβλαστικης λευχαιμιας CY1116160T1 (el)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US11232308P 2008-11-07 2008-11-07
US18329109P 2009-06-02 2009-06-02
US22126909P 2009-06-29 2009-06-29
EP09764710.1A EP2344539B1 (en) 2008-11-07 2009-11-06 Treatment of pediatric acute lymphoblastic leukemia

Publications (1)

Publication Number Publication Date
CY1116160T1 true CY1116160T1 (el) 2017-02-08

Family

ID=41796119

Family Applications (3)

Application Number Title Priority Date Filing Date
CY20151100317T CY1116160T1 (el) 2008-11-07 2015-03-31 Θεραπεια παιδιατρικης οξειας λεμφοβλαστικης λευχαιμιας
CY20181100310T CY1120022T1 (el) 2008-11-07 2018-03-14 Θεραπεια παιδιατρικης οξειας λεμφοβλαστικης λευχαιμιας
CY20191101035T CY1122428T1 (el) 2008-11-07 2019-10-03 Θεραπευτικη αγωγη της παιδιατρικης οξειας λεμφοβλαστικης λευχαιμιας με διειδικα αντισωματα εναντι cd3xcd19

Family Applications After (2)

Application Number Title Priority Date Filing Date
CY20181100310T CY1120022T1 (el) 2008-11-07 2018-03-14 Θεραπεια παιδιατρικης οξειας λεμφοβλαστικης λευχαιμιας
CY20191101035T CY1122428T1 (el) 2008-11-07 2019-10-03 Θεραπευτικη αγωγη της παιδιατρικης οξειας λεμφοβλαστικης λευχαιμιας με διειδικα αντισωματα εναντι cd3xcd19

Country Status (27)

Country Link
US (2) US20110262440A1 (el)
EP (4) EP3594237A1 (el)
JP (2) JP5798036B2 (el)
KR (1) KR101695329B1 (el)
CN (2) CN106390114A (el)
AU (1) AU2009313039B2 (el)
BR (1) BRPI0921341A2 (el)
CA (1) CA2742242C (el)
CY (3) CY1116160T1 (el)
DK (3) DK3330293T3 (el)
ES (3) ES2748126T3 (el)
HK (3) HK1158667A1 (el)
HR (3) HRP20150400T1 (el)
HU (3) HUE046222T2 (el)
IL (1) IL212651A (el)
LT (2) LT2918604T (el)
MX (1) MX2011002931A (el)
NO (1) NO2918604T3 (el)
NZ (1) NZ591312A (el)
PL (3) PL2344539T3 (el)
PT (3) PT2918604T (el)
RS (3) RS56989B1 (el)
RU (3) RU2536933C2 (el)
SG (1) SG195549A1 (el)
SI (3) SI2918604T1 (el)
SM (1) SMT201500104B (el)
WO (1) WO2010052013A1 (el)

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Publication number Publication date
BRPI0921341A2 (pt) 2016-04-26
EP2918604B1 (en) 2017-12-20
HK1215258A1 (zh) 2016-08-19
DK2918604T3 (en) 2018-03-19
SG195549A1 (en) 2013-12-30
HUE025452T2 (en) 2016-05-30
ES2535257T3 (es) 2015-05-07
HUE036922T2 (hu) 2018-08-28
DK3330293T3 (da) 2019-10-07
DK2344539T3 (en) 2015-05-04
EP2344539B1 (en) 2015-02-11
EP2918604A1 (en) 2015-09-16
JP2012508163A (ja) 2012-04-05
MX2011002931A (es) 2011-04-11
RU2018144313A3 (el) 2020-06-15
AU2009313039A1 (en) 2010-05-14
SI2918604T1 (en) 2018-04-30
NZ591312A (en) 2012-09-28
NO2918604T3 (el) 2018-05-19
CN102209729A (zh) 2011-10-05
AU2009313039B2 (en) 2015-06-18
ES2662929T3 (es) 2018-04-10
KR20110091669A (ko) 2011-08-12
CY1120022T1 (el) 2018-12-12
PL2344539T3 (pl) 2015-07-31
HK1158667A1 (en) 2012-07-20
EP3330293B1 (en) 2019-07-24
HUE046222T2 (hu) 2020-02-28
HRP20191715T1 (hr) 2019-12-13
EP3594237A1 (en) 2020-01-15
JP5798036B2 (ja) 2015-10-21
CA2742242C (en) 2023-01-10
SI2344539T1 (sl) 2015-06-30
EP2344539A1 (en) 2011-07-20
KR101695329B1 (ko) 2017-01-23
WO2010052013A1 (en) 2010-05-14
HRP20180426T1 (hr) 2018-04-20
HRP20150400T1 (hr) 2015-05-08
RU2677324C2 (ru) 2019-01-16
HK1255590B (zh) 2020-07-10
CN106390114A (zh) 2017-02-15
SI3330293T1 (sl) 2019-10-30
RU2014141180A (ru) 2016-05-10
RU2736802C2 (ru) 2020-11-20
IL212651A (en) 2015-03-31
PT2918604T (pt) 2018-03-02
RU2011122827A (ru) 2012-12-20
RS53980B1 (en) 2015-10-30
PL2918604T3 (pl) 2018-05-30
PL3330293T3 (pl) 2020-02-28
IL212651A0 (en) 2011-07-31
US20110262440A1 (en) 2011-10-27
JP2015232023A (ja) 2015-12-24
JP6130451B2 (ja) 2017-05-17
PT2344539E (pt) 2015-04-01
US20230235053A1 (en) 2023-07-27
SMT201500104B (it) 2015-07-09
RU2018144313A (ru) 2020-06-15
ES2748126T3 (es) 2020-03-13
RU2014141180A3 (el) 2018-06-09
RS56989B1 (sr) 2018-05-31
CA2742242A1 (en) 2010-05-14
LT3330293T (lt) 2019-10-10
LT2918604T (lt) 2018-03-26
CN102209729B (zh) 2016-05-25
PT3330293T (pt) 2019-10-18
CY1122428T1 (el) 2021-01-27
EP3330293A1 (en) 2018-06-06
RU2536933C2 (ru) 2014-12-27
RS59348B1 (sr) 2019-10-31

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