SK68997A3 - Use of metal complexes as liver and gall bladder radiodiagnosis agents in computer tomography - Google Patents

Use of metal complexes as liver and gall bladder radiodiagnosis agents in computer tomography Download PDF

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Publication number
SK68997A3
SK68997A3 SK689-97A SK68997A SK68997A3 SK 68997 A3 SK68997 A3 SK 68997A3 SK 68997 A SK68997 A SK 68997A SK 68997 A3 SK68997 A3 SK 68997A3
Authority
SK
Slovakia
Prior art keywords
formula
independently
metal
radical
mmol
Prior art date
Application number
SK689-97A
Other languages
English (en)
Slovak (sk)
Inventor
Franz-Karl Maier
Michael Bauer
Werner Krause
Ulrich Speck
Gabriele Schuhmann-Giampieri
Andreas Muhler
Thomas Balzer
Wolf-Rudiger Press
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of SK68997A3 publication Critical patent/SK68997A3/sk

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/0004—Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/101—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
    • A61K49/103—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being acyclic, e.g. DTPA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Endocrinology (AREA)
  • Pathology (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
SK689-97A 1994-11-30 1995-11-20 Use of metal complexes as liver and gall bladder radiodiagnosis agents in computer tomography SK68997A3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US35108694A 1994-11-30 1994-11-30
US38740895A 1995-02-13 1995-02-13
PCT/DE1995/001644 WO1996016677A2 (de) 1994-11-30 1995-11-20 Verwendung von metallkomplexen als leber- und gallen-röntgendiagnostika in der computertomographie

Publications (1)

Publication Number Publication Date
SK68997A3 true SK68997A3 (en) 1997-11-05

Family

ID=26996938

Family Applications (1)

Application Number Title Priority Date Filing Date
SK689-97A SK68997A3 (en) 1994-11-30 1995-11-20 Use of metal complexes as liver and gall bladder radiodiagnosis agents in computer tomography

Country Status (15)

Country Link
US (4) US5672335A (no)
EP (3) EP0794799A2 (no)
JP (3) JPH10511934A (no)
CN (1) CN1167444A (no)
AU (3) AU3922795A (no)
CA (3) CA2206522A1 (no)
CZ (1) CZ166897A3 (no)
FI (3) FI972287A (no)
HU (1) HUT77284A (no)
IL (3) IL116209A0 (no)
MX (1) MX9703880A (no)
NO (3) NO972460D0 (no)
PL (1) PL320462A1 (no)
SK (1) SK68997A3 (no)
WO (3) WO1996016928A1 (no)

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US6458337B1 (en) 1996-08-02 2002-10-01 Dibra S.P.A Diagnostic imaging contrast agent with improved in serum relaxivity
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US6558669B1 (en) 1996-08-28 2003-05-06 Immunomedics, Inc. Stable radioiodine conjugates and methods for their synthesis
US7521531B2 (en) 1996-08-28 2009-04-21 Immunomedics, Inc. Methods for the purification of stable radioiodine conjugates
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US6019959A (en) * 1997-07-31 2000-02-01 Schering Aktiengesellschaft Oligomeric compounds that contain perfluoroalkyl, process for their production, and their use in NMR diagnosis
US6153655A (en) 1998-04-17 2000-11-28 Enzon, Inc. Terminally-branched polymeric linkers and polymeric conjugates containing the same
US6767741B1 (en) * 1999-08-27 2004-07-27 Invitrogen Corporation Metal binding compounds and their use in cell culture medium compositions
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DE10127126A1 (de) * 2001-06-05 2002-12-19 Forschungszentrum Juelich Gmbh Geschützte Tyrosinderivate, Verfahren zu deren Herstellung und deren Verwendung zur Herstellung von O-(2-[·18·F]-Fluorethyl)-L-tyrosin
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EP2849804A1 (en) * 2012-05-18 2015-03-25 Bayer Pharma Aktiengesellschaft Bis azainositol heavy metal complexes for x-ray imaging
BR102013023479B1 (pt) * 2013-09-12 2022-07-26 Uniao Brasileira De Educação E Assistência Processo de síntese de compostos de coordenação à base de lantanídeo
CN109613177B (zh) 2014-07-01 2021-08-20 科蒙森斯公司 用于鉴定羊水的诊断组合物
EP3101012A1 (en) 2015-06-04 2016-12-07 Bayer Pharma Aktiengesellschaft New gadolinium chelate compounds for use in magnetic resonance imaging
JP7034160B2 (ja) 2016-11-28 2022-03-11 バイエル・ファルマ・アクティエンゲゼルシャフト 磁気共鳴画像法に使用するための高緩和度ガドリニウムキレート化合物
JP6836471B2 (ja) 2017-07-20 2021-03-03 株式会社神戸製鋼所 流体流通装置
JP7120802B2 (ja) 2017-07-20 2022-08-17 株式会社神戸製鋼所 流体流通装置及びその流通異常検知方法
CN107573291A (zh) * 2017-10-27 2018-01-12 上海司太立制药有限公司 一种钆塞酸二钠配体杂质的制备方法和用途
PE20211471A1 (es) 2018-11-23 2021-08-05 Bayer Ag Formulacion de medios de contraste y proceso para prepararlos
EP4059925A1 (en) 2021-03-15 2022-09-21 Bayer Aktiengesellschaft New contrast agent for use in magnetic resonance imaging
EP4335840A1 (en) 2022-09-09 2024-03-13 Bayer Aktiengesellschaft New contrast agents for use in diagnostic imaging
EP4335462A1 (en) 2022-09-09 2024-03-13 Bayer AG Contrast agents for use in diagnostic computed tomography imaging

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Also Published As

Publication number Publication date
EP0794939A1 (de) 1997-09-17
NO972459L (no) 1997-07-29
FI972287A0 (fi) 1997-05-29
WO1996016928A1 (de) 1996-06-06
US5885548A (en) 1999-03-23
IL116208A0 (en) 1996-01-31
JPH10511934A (ja) 1998-11-17
CZ166897A3 (en) 1997-09-17
CA2206397A1 (en) 1996-06-06
WO1996016677A2 (de) 1996-06-06
HUT77284A (hu) 1998-03-30
NO972460L (no) 1997-05-29
AU4254696A (en) 1996-06-19
FI972286A (fi) 1997-05-29
FI972288A0 (fi) 1997-05-29
EP0794938A1 (de) 1997-09-17
CA2206576A1 (en) 1996-06-06
US5853699A (en) 1998-12-29
NO972457L (no) 1997-07-30
US5672335A (en) 1997-09-30
IL116209A0 (en) 1996-01-31
CA2206522A1 (en) 1996-06-06
NO972457D0 (no) 1997-05-29
EP0794799A2 (de) 1997-09-17
WO1996016929A1 (de) 1996-06-06
US5746995A (en) 1998-05-05
PL320462A1 (en) 1997-09-29
IL116206A0 (en) 1996-01-31
JPH10509961A (ja) 1998-09-29
AU4299496A (en) 1996-06-19
NO972459D0 (no) 1997-05-29
NO972460D0 (no) 1997-05-29
FI972288A (fi) 1997-05-29
FI972286A0 (fi) 1997-05-29
JPH11503405A (ja) 1999-03-26
AU3922795A (en) 1996-06-19
MX9703880A (es) 1997-08-30
CN1167444A (zh) 1997-12-10
WO1996016677A3 (de) 1996-09-12
FI972287A (fi) 1997-05-29

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