SK68997A3 - Use of metal complexes as liver and gall bladder radiodiagnosis agents in computer tomography - Google Patents

Use of metal complexes as liver and gall bladder radiodiagnosis agents in computer tomography Download PDF

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Publication number
SK68997A3
SK68997A3 SK689-97A SK68997A SK68997A3 SK 68997 A3 SK68997 A3 SK 68997A3 SK 68997 A SK68997 A SK 68997A SK 68997 A3 SK68997 A3 SK 68997A3
Authority
SK
Slovakia
Prior art keywords
formula
independently
metal
radical
mmol
Prior art date
Application number
SK689-97A
Other languages
English (en)
Slovak (sk)
Inventor
Franz-Karl Maier
Michael Bauer
Werner Krause
Ulrich Speck
Gabriele Schuhmann-Giampieri
Andreas Muhler
Thomas Balzer
Wolf-Rudiger Press
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of SK68997A3 publication Critical patent/SK68997A3/sk

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/0002General or multifunctional contrast agents, e.g. chelated agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/0004Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/04X-ray contrast preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10Organic compounds
    • A61K49/101Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
    • A61K49/103Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being acyclic, e.g. DTPA
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/02Antidotes
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/24Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry
SK689-97A 1994-11-30 1995-11-20 Use of metal complexes as liver and gall bladder radiodiagnosis agents in computer tomography SK68997A3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US35108694A 1994-11-30 1994-11-30
US38740895A 1995-02-13 1995-02-13
PCT/DE1995/001644 WO1996016677A2 (de) 1994-11-30 1995-11-20 Verwendung von metallkomplexen als leber- und gallen-röntgendiagnostika in der computertomographie

Publications (1)

Publication Number Publication Date
SK68997A3 true SK68997A3 (en) 1997-11-05

Family

ID=26996938

Family Applications (1)

Application Number Title Priority Date Filing Date
SK689-97A SK68997A3 (en) 1994-11-30 1995-11-20 Use of metal complexes as liver and gall bladder radiodiagnosis agents in computer tomography

Country Status (15)

Country Link
US (4) US5672335A (hr)
EP (3) EP0794939A1 (hr)
JP (3) JPH10511934A (hr)
CN (1) CN1167444A (hr)
AU (3) AU4254696A (hr)
CA (3) CA2206576A1 (hr)
CZ (1) CZ166897A3 (hr)
FI (3) FI972288A (hr)
HU (1) HUT77284A (hr)
IL (3) IL116208A0 (hr)
MX (1) MX9703880A (hr)
NO (3) NO972459L (hr)
PL (1) PL320462A1 (hr)
SK (1) SK68997A3 (hr)
WO (3) WO1996016677A2 (hr)

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US6019959A (en) * 1997-07-31 2000-02-01 Schering Aktiengesellschaft Oligomeric compounds that contain perfluoroalkyl, process for their production, and their use in NMR diagnosis
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US6767741B1 (en) 1999-08-27 2004-07-27 Invitrogen Corporation Metal binding compounds and their use in cell culture medium compositions
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DE10127126A1 (de) * 2001-06-05 2002-12-19 Forschungszentrum Juelich Gmbh Geschützte Tyrosinderivate, Verfahren zu deren Herstellung und deren Verwendung zur Herstellung von O-(2-[·18·F]-Fluorethyl)-L-tyrosin
US6627394B2 (en) 2001-07-19 2003-09-30 Common Sense Ltd. Diagnostic pad
CA2581639C (en) 2004-09-30 2016-07-26 Molecular Devices Corporation Luminescent lanthanide complexes
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US10071174B2 (en) 2011-06-06 2018-09-11 Portland State University Bismuth particle X-ray contrast agents
EP2849804A1 (en) * 2012-05-18 2015-03-25 Bayer Pharma Aktiengesellschaft Bis azainositol heavy metal complexes for x-ray imaging
BR102013023479B1 (pt) * 2013-09-12 2022-07-26 Uniao Brasileira De Educação E Assistência Processo de síntese de compostos de coordenação à base de lantanídeo
CN109613177B (zh) 2014-07-01 2021-08-20 科蒙森斯公司 用于鉴定羊水的诊断组合物
EP3101012A1 (en) 2015-06-04 2016-12-07 Bayer Pharma Aktiengesellschaft New gadolinium chelate compounds for use in magnetic resonance imaging
EP3544964B1 (en) 2016-11-28 2020-06-17 Bayer Pharma Aktiengesellschaft High relaxivity gadolinium chelate compounds for use in magnetic resonance imaging
JP7120802B2 (ja) 2017-07-20 2022-08-17 株式会社神戸製鋼所 流体流通装置及びその流通異常検知方法
JP6836471B2 (ja) 2017-07-20 2021-03-03 株式会社神戸製鋼所 流体流通装置
CN107573291A (zh) * 2017-10-27 2018-01-12 上海司太立制药有限公司 一种钆塞酸二钠配体杂质的制备方法和用途
AU2019382881A1 (en) 2018-11-23 2021-05-20 Bayer Aktiengesellschaft Formulation of contrast media and process of preparation thereof
EP4059925A1 (en) 2021-03-15 2022-09-21 Bayer Aktiengesellschaft New contrast agent for use in magnetic resonance imaging
EP4335462A1 (en) 2022-09-09 2024-03-13 Bayer AG Contrast agents for use in diagnostic computed tomography imaging
EP4335840A1 (en) 2022-09-09 2024-03-13 Bayer Aktiengesellschaft New contrast agents for use in diagnostic imaging

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Also Published As

Publication number Publication date
FI972288A0 (fi) 1997-05-29
NO972459D0 (no) 1997-05-29
WO1996016928A1 (de) 1996-06-06
US5885548A (en) 1999-03-23
FI972286A (fi) 1997-05-29
FI972287A (fi) 1997-05-29
CN1167444A (zh) 1997-12-10
NO972460D0 (no) 1997-05-29
JPH11503405A (ja) 1999-03-26
JPH10511934A (ja) 1998-11-17
EP0794938A1 (de) 1997-09-17
FI972288A (fi) 1997-05-29
AU4299496A (en) 1996-06-19
IL116206A0 (en) 1996-01-31
FI972287A0 (fi) 1997-05-29
FI972286A0 (fi) 1997-05-29
US5672335A (en) 1997-09-30
CA2206576A1 (en) 1996-06-06
IL116209A0 (en) 1996-01-31
NO972460L (no) 1997-05-29
PL320462A1 (en) 1997-09-29
EP0794799A2 (de) 1997-09-17
WO1996016677A2 (de) 1996-06-06
WO1996016677A3 (de) 1996-09-12
NO972457L (no) 1997-07-30
JPH10509961A (ja) 1998-09-29
US5746995A (en) 1998-05-05
US5853699A (en) 1998-12-29
NO972457D0 (no) 1997-05-29
IL116208A0 (en) 1996-01-31
MX9703880A (es) 1997-08-30
EP0794939A1 (de) 1997-09-17
NO972459L (no) 1997-07-29
AU3922795A (en) 1996-06-19
WO1996016929A1 (de) 1996-06-06
HUT77284A (hu) 1998-03-30
CZ166897A3 (en) 1997-09-17
CA2206397A1 (en) 1996-06-06
AU4254696A (en) 1996-06-19
CA2206522A1 (en) 1996-06-06

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