SK67298A3 - Solid mixtures of cyclodextrins prepared via melt-extrusion - Google Patents
Solid mixtures of cyclodextrins prepared via melt-extrusion Download PDFInfo
- Publication number
- SK67298A3 SK67298A3 SK672-98A SK67298A SK67298A3 SK 67298 A3 SK67298 A3 SK 67298A3 SK 67298 A SK67298 A SK 67298A SK 67298 A3 SK67298 A3 SK 67298A3
- Authority
- SK
- Slovakia
- Prior art keywords
- cyclodextrin
- mixture
- solid
- active ingredient
- melt
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
- A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Nanotechnology (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP95203219 | 1995-11-23 | ||
PCT/EP1996/005118 WO1997018839A1 (en) | 1995-11-23 | 1996-11-20 | Solid mixtures of cyclodextrins prepared via melt-extrusion |
US09/081,808 US6365188B1 (en) | 1995-11-23 | 1998-05-20 | Solid mixtures of cyclodextrins prepared via meltextrusion |
Publications (1)
Publication Number | Publication Date |
---|---|
SK67298A3 true SK67298A3 (en) | 1998-11-04 |
Family
ID=26139823
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SK672-98A SK67298A3 (en) | 1995-11-23 | 1996-11-20 | Solid mixtures of cyclodextrins prepared via melt-extrusion |
Country Status (16)
Country | Link |
---|---|
US (1) | US6365188B1 (ja) |
EP (1) | EP0862463A1 (ja) |
JP (1) | JP3310299B2 (ja) |
CN (1) | CN1198655C (ja) |
AU (1) | AU725204B2 (ja) |
BR (1) | BR9611562A (ja) |
CZ (1) | CZ154398A3 (ja) |
HU (1) | HUP9900730A3 (ja) |
IL (1) | IL123654A (ja) |
NO (1) | NO981078L (ja) |
NZ (1) | NZ322907A (ja) |
PL (1) | PL189122B1 (ja) |
SK (1) | SK67298A3 (ja) |
TR (1) | TR199800729T2 (ja) |
WO (1) | WO1997018839A1 (ja) |
ZA (1) | ZA969831B (ja) |
Families Citing this family (51)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL123654A (en) * | 1995-11-23 | 2001-08-08 | Janssen Pharmaceutica Nv | Process for the preparation of solid mixtures of cyclodextrins and pharmaceutical preparations containing such solid mixtures |
KR19990001564A (ko) | 1997-06-16 | 1999-01-15 | 유충식 | 용해도를 개선한 아졸계 항진균제 및 이를 함유하는 제제 |
US6547997B1 (en) | 1997-11-28 | 2003-04-15 | Abbot Laboratories | Method for producing solvent-free noncrystalline biologically active substances |
US6683100B2 (en) | 1999-01-19 | 2004-01-27 | Novartis Ag | Organic compounds |
US6194181B1 (en) | 1998-02-19 | 2001-02-27 | Novartis Ag | Fermentative preparation process for and crystal forms of cytostatics |
SK287270B6 (sk) | 1998-11-10 | 2010-05-07 | Janssen Pharmaceutica N. V. | Derivát pyrimidínu |
US6194395B1 (en) | 1999-02-25 | 2001-02-27 | Orthro-Mcneil Pharmaceutical, Inc. | Cyclodextrin cladribine formulations |
DE19911097A1 (de) * | 1999-03-12 | 2000-09-14 | Basf Ag | Verfahren zur Herstellung von festen cyclodextrinhaltigen Dosierungsformen |
WO2000056726A1 (en) | 1999-03-24 | 2000-09-28 | Fmc Corporation | Improved aqueous solubility pharmaceutical formulations |
EP1177192B1 (en) | 1999-05-04 | 2003-03-19 | Janssen Pharmaceutica N.V. | Antifungal ethers |
FR2803748A1 (fr) * | 2000-01-14 | 2001-07-20 | Ethypharm Lab Prod Ethiques | Composition d'itraconazole et procede de preparation |
WO2001064674A1 (en) | 2000-03-01 | 2001-09-07 | Janssen Pharmaceutica N.V. | 2,4-disubstituted thiazolyl derivatives |
US6835717B2 (en) * | 2000-03-08 | 2004-12-28 | The Johns Hopkins University School Of Medicine | β-cyclodextrin compositions, and use to prevent transmission of sexually transmitted diseases |
US7276510B2 (en) | 2000-05-08 | 2007-10-02 | Janssen Pharmaceutica, Inc. | HIV replication inhibitors |
ITRN20000051A1 (it) | 2000-12-22 | 2002-06-22 | Ascor Chimici Srl | Metodo e apparecchiatura per formare sferule composite contenenti principi attivi del tipo farmaceutico e/o integratori alimentari o cosmeti |
GB0113841D0 (en) * | 2001-06-07 | 2001-08-01 | Boots Co Plc | Therapeutic agents |
JO3429B1 (ar) | 2001-08-13 | 2019-10-20 | Janssen Pharmaceutica Nv | مشتقات برميدينات مثبطة فيروس الايدز |
US8101629B2 (en) | 2001-08-13 | 2012-01-24 | Janssen Pharmaceutica N.V. | Salt of 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]benzonitrile |
CN100496493C (zh) | 2001-08-13 | 2009-06-10 | 詹森药业有限公司 | 2-氨基-4,5-三取代噻唑基衍生物 |
US7638522B2 (en) | 2001-08-13 | 2009-12-29 | Janssen Pharmaceutica N.V. | Salt of 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino] benzonitrile |
DE60333260D1 (en) | 2002-03-13 | 2010-08-19 | Janssen Pharmaceutica Nv | Histone-deacetylase-inhibitoren |
US7767679B2 (en) | 2002-03-13 | 2010-08-03 | Janssen Pharmaceutica N.V. | Sulfonylamino-derivatives as novel inhibitors of histone deacetylase |
CA2493794C (en) | 2002-08-09 | 2010-05-25 | Janssen Pharmaceutica N.V. | Processes for the preparation of 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]benzonitrile |
CL2004000192A1 (es) | 2003-02-07 | 2005-03-18 | Janssen Pharmaceutica Nv | Uso de compuestos derivados de 2-aminopirimidina para preparar un medicamento para la prevencion de una infeccion por vih relaciones sexuales o un contacto intimo en la pareja. |
KR20050105190A (ko) | 2003-02-07 | 2005-11-03 | 얀센 파마슈티카 엔.브이. | Hiv를 저해하는 1,2,4-트리아진 |
CL2004000303A1 (es) | 2003-02-20 | 2005-04-08 | Tibotec Pharm Ltd | Compuestos derivados de pirimidinas y triazinas; proceso de preparacion; composicion farmaceutica; y su uso para inhibir la replicacion del vih. |
CA2520522C (en) | 2003-03-28 | 2012-05-29 | Ivax Corporation | Cladribine formulations for improved oral and transmucosal delivery |
CA2520523C (en) * | 2003-03-28 | 2011-10-11 | Ivax Corporation | Oral formulations of cladribine |
AU2004274185B2 (en) | 2003-09-25 | 2009-12-10 | Janssen Pharmaceutica N.V. | HIV replication inhibiting purine derivatives |
US20050118265A1 (en) * | 2003-11-28 | 2005-06-02 | Anandi Krishnan | Antifungal oral dosage forms and the methods for preparation |
PL1781639T3 (pl) | 2004-07-28 | 2012-07-31 | Janssen Pharmaceutica Nv | Podstawione pochodne indolilo-alkiloaminowe jako nowe inhibitory deacetylazy histonowej |
CN101035773B (zh) | 2004-08-10 | 2012-06-06 | 詹森药业有限公司 | 抑制hiv的1,2,4-三嗪-6-酮衍生物 |
KR20070057899A (ko) | 2004-09-30 | 2007-06-07 | 티보텍 파마슈티칼즈 리미티드 | Hiv를 억제하는 5-헤테로사이클릴피리미딘 |
TW200626561A (en) | 2004-09-30 | 2006-08-01 | Tibotec Pharm Ltd | HIV inhibiting 5-substituted pyrimidines |
RU2403254C2 (ru) | 2004-10-29 | 2010-11-10 | Тиботек Фармасьютикалз Лтд. | Бициклические производные пиримидина, ингибирующие вич |
EP1853568B1 (en) | 2005-01-27 | 2011-09-07 | Tibotec Pharmaceuticals | Hiv inhibiting 2-(4-cyanophenylamino)pyrimidine derivatives |
ME01229B (me) | 2005-03-04 | 2013-06-20 | Janssen R& D Ireland | 2-(4-cijanofenil)-6-hidroksilaminopirimidini koji inhibiraju hiv |
DK1912626T3 (en) * | 2005-08-08 | 2016-08-01 | Abbvie Deutschland | Dosage forms with improved bioavailability |
WO2007047253A2 (en) * | 2005-10-11 | 2007-04-26 | Eastman Chemical Company | Pharmaceutical formulations of cyclodextrins and antifungal azole compounds |
AU2007206942B2 (en) | 2006-01-19 | 2012-08-23 | Janssen Pharmaceutica N.V. | Pyridine and pyrimidine derivatives as inhibitors of histone deacetylase |
EP1832281A1 (en) * | 2006-03-10 | 2007-09-12 | Abbott GmbH & Co. KG | Process for producing a solid dispersion of an active ingredient |
CA2645959C (en) | 2006-03-30 | 2016-05-17 | Tibotec Pharmaceuticals Ltd. | Hiv inhibiting 5-(hydroxymethylene and aminomethylene) substituted pyrimidines |
BRPI0709690B8 (pt) | 2006-03-30 | 2021-05-25 | Janssen R & D Ireland | 5-amido pirimidinas substituídas e composição farmacêutica que as compreende |
DK2114901T3 (da) | 2006-12-29 | 2014-06-30 | Janssen R & D Ireland | Hiv-inhiberende 6-substituerede pyrimidiner |
KR20090094084A (ko) | 2006-12-29 | 2009-09-03 | 티보텍 파마슈티칼즈 리미티드 | Hiv를 억제하는 5,6-치환된 피리미딘 |
US20110037185A1 (en) * | 2008-04-30 | 2011-02-17 | James Kowalski | Continuous process for making pharmaceutical compositions |
EP2427166B1 (en) | 2009-05-07 | 2013-10-16 | Gea Pharma Systems Limited | Tablet production module and method for continuous production of tablets |
US20120148678A1 (en) | 2010-12-08 | 2012-06-14 | Advanced Technologies And Regenerative Medicine, Llc. | Sustained release of poorly water soluble active compounds |
US10532102B2 (en) | 2016-08-19 | 2020-01-14 | Foresee Pharmaceuticals Co., Ltd. | Pharmaceutical composition and methods of uses |
CN107441504A (zh) * | 2017-09-06 | 2017-12-08 | 广州中医药大学 | 番茄红素包合物及其制备方法及番茄红素包合物片剂、胶囊和颗粒 |
CN110898015A (zh) * | 2019-12-31 | 2020-03-24 | 上海汉维生物医药科技有限公司 | 一种伊曲康唑制剂的制备方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS61152765A (ja) * | 1984-12-27 | 1986-07-11 | Nippon Ekishiyou Kk | シクロデキストリン類で包接された化合物を含有した合成樹脂製品及びその製造方法 |
US5009900A (en) * | 1989-10-02 | 1991-04-23 | Nabisco Brands, Inc. | Glassy matrices containing volatile and/or labile components, and processes for preparation and use thereof |
DE69327877T2 (de) * | 1992-10-14 | 2000-10-05 | Nippon Shinyaku Co., Ltd. | Verfahren zur verschiebung eines kristallzustandes |
WO1994011031A1 (en) * | 1992-11-10 | 1994-05-26 | Nippon Shinyaku Co., Ltd. | Enclosure compound manufacturing method |
FR2705677B1 (fr) * | 1993-05-28 | 1995-08-11 | Roquette Freres | Micro-granules obtenus par extrusion-sphéronisation contenant une cyclodextrine. |
IL123654A (en) * | 1995-11-23 | 2001-08-08 | Janssen Pharmaceutica Nv | Process for the preparation of solid mixtures of cyclodextrins and pharmaceutical preparations containing such solid mixtures |
KR100331529B1 (ko) | 1999-06-16 | 2002-04-06 | 민경윤 | 난용성 항진균제의 경구투여용 조성물 및 그의 제조 방법 |
-
1996
- 1996-11-20 IL IL12365496A patent/IL123654A/en not_active IP Right Cessation
- 1996-11-20 CN CNB961979348A patent/CN1198655C/zh not_active Expired - Fee Related
- 1996-11-20 HU HU9900730A patent/HUP9900730A3/hu unknown
- 1996-11-20 CZ CZ981543A patent/CZ154398A3/cs unknown
- 1996-11-20 AU AU76943/96A patent/AU725204B2/en not_active Ceased
- 1996-11-20 TR TR1998/00729T patent/TR199800729T2/xx unknown
- 1996-11-20 JP JP51939397A patent/JP3310299B2/ja not_active Expired - Fee Related
- 1996-11-20 BR BR9611562A patent/BR9611562A/pt not_active Application Discontinuation
- 1996-11-20 NZ NZ322907A patent/NZ322907A/xx unknown
- 1996-11-20 WO PCT/EP1996/005118 patent/WO1997018839A1/en not_active Application Discontinuation
- 1996-11-20 PL PL96326161A patent/PL189122B1/pl not_active IP Right Cessation
- 1996-11-20 SK SK672-98A patent/SK67298A3/sk unknown
- 1996-11-20 EP EP96939864A patent/EP0862463A1/en not_active Withdrawn
- 1996-11-22 ZA ZA9609831A patent/ZA969831B/xx unknown
-
1998
- 1998-03-11 NO NO981078A patent/NO981078L/no not_active Application Discontinuation
- 1998-05-20 US US09/081,808 patent/US6365188B1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
AU725204B2 (en) | 2000-10-05 |
EP0862463A1 (en) | 1998-09-09 |
PL326161A1 (en) | 1998-08-31 |
ZA969831B (en) | 1998-05-22 |
JPH11501050A (ja) | 1999-01-26 |
NO981078L (no) | 1998-05-22 |
PL189122B1 (pl) | 2005-06-30 |
CN1198655C (zh) | 2005-04-27 |
NO981078D0 (no) | 1998-03-11 |
CZ154398A3 (cs) | 1998-08-12 |
US6365188B1 (en) | 2002-04-02 |
WO1997018839A1 (en) | 1997-05-29 |
BR9611562A (pt) | 1999-03-02 |
HUP9900730A2 (hu) | 1999-07-28 |
IL123654A (en) | 2001-08-08 |
AU7694396A (en) | 1997-06-11 |
CN1200677A (zh) | 1998-12-02 |
NZ322907A (en) | 1998-12-23 |
IL123654A0 (en) | 1998-10-30 |
HUP9900730A3 (en) | 2001-04-28 |
JP3310299B2 (ja) | 2002-08-05 |
TR199800729T2 (xx) | 1998-07-21 |
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