ZA969831B - Solid mixtures of cyclodextrins prepared via melt-extrusion. - Google Patents
Solid mixtures of cyclodextrins prepared via melt-extrusion.Info
- Publication number
- ZA969831B ZA969831B ZA9609831A ZA969831A ZA969831B ZA 969831 B ZA969831 B ZA 969831B ZA 9609831 A ZA9609831 A ZA 9609831A ZA 969831 A ZA969831 A ZA 969831A ZA 969831 B ZA969831 B ZA 969831B
- Authority
- ZA
- South Africa
- Prior art keywords
- extrusion
- prepared via
- solid mixtures
- via melt
- cyclodextrins prepared
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
- A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Nanotechnology (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP95203219 | 1995-11-23 | ||
US09/081,808 US6365188B1 (en) | 1995-11-23 | 1998-05-20 | Solid mixtures of cyclodextrins prepared via meltextrusion |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA969831B true ZA969831B (en) | 1998-05-22 |
Family
ID=26139823
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA9609831A ZA969831B (en) | 1995-11-23 | 1996-11-22 | Solid mixtures of cyclodextrins prepared via melt-extrusion. |
Country Status (16)
Country | Link |
---|---|
US (1) | US6365188B1 (xx) |
EP (1) | EP0862463A1 (xx) |
JP (1) | JP3310299B2 (xx) |
CN (1) | CN1198655C (xx) |
AU (1) | AU725204B2 (xx) |
BR (1) | BR9611562A (xx) |
CZ (1) | CZ154398A3 (xx) |
HU (1) | HUP9900730A3 (xx) |
IL (1) | IL123654A (xx) |
NO (1) | NO981078L (xx) |
NZ (1) | NZ322907A (xx) |
PL (1) | PL189122B1 (xx) |
SK (1) | SK67298A3 (xx) |
TR (1) | TR199800729T2 (xx) |
WO (1) | WO1997018839A1 (xx) |
ZA (1) | ZA969831B (xx) |
Families Citing this family (51)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CZ154398A3 (cs) * | 1995-11-23 | 1998-08-12 | Janssen Pharmaceutica N.V. | Pevné směsi cyklodextrinů připravené vytlačováním taveniny |
KR19990001564A (ko) | 1997-06-16 | 1999-01-15 | 유충식 | 용해도를 개선한 아졸계 항진균제 및 이를 함유하는 제제 |
CA2310847C (en) | 1997-11-28 | 2007-03-13 | Knoll Aktiengesellschaft | Method for producing solvent-free non-crystalline biologically active substances |
US6683100B2 (en) | 1999-01-19 | 2004-01-27 | Novartis Ag | Organic compounds |
US6194181B1 (en) | 1998-02-19 | 2001-02-27 | Novartis Ag | Fermentative preparation process for and crystal forms of cytostatics |
CZ301367B6 (cs) | 1998-11-10 | 2010-02-03 | Janssen Pharmaceutica N. V. | Derivát pyrimidinu, zpusob a meziprodukty pro jeho prípravu a lécivo pro lécení HIV na jeho bázi |
US6194395B1 (en) | 1999-02-25 | 2001-02-27 | Orthro-Mcneil Pharmaceutical, Inc. | Cyclodextrin cladribine formulations |
DE19911097A1 (de) * | 1999-03-12 | 2000-09-14 | Basf Ag | Verfahren zur Herstellung von festen cyclodextrinhaltigen Dosierungsformen |
ATE307808T1 (de) | 1999-03-24 | 2005-11-15 | Scherer Technologies Inc R P | Pharmazeutische formulierungen mit verbesserter löslichkeit in wasser |
JP4610744B2 (ja) | 1999-05-04 | 2011-01-12 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | 抗菌・抗カビ性エーテル類 |
FR2803748A1 (fr) * | 2000-01-14 | 2001-07-20 | Ethypharm Lab Prod Ethiques | Composition d'itraconazole et procede de preparation |
AU3740101A (en) | 2000-03-01 | 2001-09-12 | Janssen Pharmaceutica Nv | 2,4-disubstituted thiazolyl derivatives |
US6835717B2 (en) * | 2000-03-08 | 2004-12-28 | The Johns Hopkins University School Of Medicine | β-cyclodextrin compositions, and use to prevent transmission of sexually transmitted diseases |
JP5230050B2 (ja) | 2000-05-08 | 2013-07-10 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | Hiv複製阻害剤 |
ITRN20000051A1 (it) | 2000-12-22 | 2002-06-22 | Ascor Chimici Srl | Metodo e apparecchiatura per formare sferule composite contenenti principi attivi del tipo farmaceutico e/o integratori alimentari o cosmeti |
GB0113841D0 (en) * | 2001-06-07 | 2001-08-01 | Boots Co Plc | Therapeutic agents |
US8101629B2 (en) | 2001-08-13 | 2012-01-24 | Janssen Pharmaceutica N.V. | Salt of 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]benzonitrile |
IL160329A0 (en) | 2001-08-13 | 2004-07-25 | Janssen Pharmaceutica Nv | 2-amino-4,5-trisubstituted thiazolyl derivatives |
US7638522B2 (en) | 2001-08-13 | 2009-12-29 | Janssen Pharmaceutica N.V. | Salt of 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino] benzonitrile |
JO3429B1 (ar) | 2001-08-13 | 2019-10-20 | Janssen Pharmaceutica Nv | مشتقات برميدينات مثبطة فيروس الايدز |
WO2003075929A1 (en) | 2002-03-13 | 2003-09-18 | Janssen Pharmaceutica N.V. | Inhibitors of histone deacetylase |
ATE396971T1 (de) | 2002-03-13 | 2008-06-15 | Janssen Pharmaceutica Nv | Sulfonylaminoderivate als neue inhibitoren von histondeacetylase |
WO2004016581A1 (en) | 2002-08-09 | 2004-02-26 | Janssen Pharmaceutica N.V. | Processes for the preparation of 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]benzonitrile |
AP2005003365A0 (en) | 2003-02-07 | 2005-09-30 | Janssen Pharmaceutica Nv | Hiv inhibiting 1, 2, 4-triazines. |
KR20110132482A (ko) | 2003-02-07 | 2011-12-07 | 얀센 파마슈티카 엔.브이. | Hiv 감염 예방용 피리미딘 유도체 |
CL2004000303A1 (es) | 2003-02-20 | 2005-04-08 | Tibotec Pharm Ltd | Compuestos derivados de pirimidinas y triazinas; proceso de preparacion; composicion farmaceutica; y su uso para inhibir la replicacion del vih. |
MEP34508A (en) * | 2003-03-28 | 2011-02-10 | Ares Trading Sa | Cladribine formulations for improved oral and transmucosal delivery |
RS20050735A (xx) * | 2003-03-28 | 2008-06-05 | Ares Trading S.A., | Formulacije kladribina za poboljšanu oralnu i transmukoznu primenu |
DE602004031641D1 (de) | 2003-09-25 | 2011-04-14 | Janssen Pharmaceutica Nv | Die replikation von hiv hemmende purinderivate |
US20050118265A1 (en) * | 2003-11-28 | 2005-06-02 | Anandi Krishnan | Antifungal oral dosage forms and the methods for preparation |
EA010652B1 (ru) | 2004-07-28 | 2008-10-30 | Янссен Фармацевтика Н.В. | Замещенные индолильные алкиламинопроизводные в качестве новых ингибиторов гистондеацетилазы |
EP1797050B1 (en) | 2004-08-10 | 2013-10-23 | Janssen Pharmaceutica NV | Hiv inhibiting 1.2.4-triazin-6-one derivates |
TW200626574A (en) | 2004-09-30 | 2006-08-01 | Tibotec Pharm Ltd | HIV inhibiting 5-heterocyclyl pyrimidines |
MX2007003796A (es) | 2004-09-30 | 2007-04-25 | Tibotec Pharm Ltd | Pirimidinas 5-sustituidas inhibidoras del virus de inmunodeficiencia humana. |
CA2577588C (en) | 2004-10-29 | 2013-09-10 | Tibotec Pharmaceuticals Ltd. | Hiv inhibiting bicyclic pyrimidine derivatives |
CN101107234B (zh) | 2005-01-27 | 2013-06-19 | 泰博特克药品有限公司 | 抑制hiv的2-(4-氰基苯氨基)嘧啶衍生物 |
BRPI0609291B1 (pt) | 2005-03-04 | 2022-02-08 | Janssen Sciences Ireland Uc | 2-(4-ciano-fenil)-o-hidroxilamina-pirimidinas que inibem hiv, composição farmacêutica que as compreende e processo para a preparação de ambas |
DK1912626T3 (en) * | 2005-08-08 | 2016-08-01 | Abbvie Deutschland | Dosage forms with improved bioavailability |
WO2007047253A2 (en) * | 2005-10-11 | 2007-04-26 | Eastman Chemical Company | Pharmaceutical formulations of cyclodextrins and antifungal azole compounds |
WO2007082874A1 (en) | 2006-01-19 | 2007-07-26 | Janssen Pharmaceutica N.V. | Pyridine and pyrimidine derivatives as inhibitors of histone deacetylase |
EP1832281A1 (en) * | 2006-03-10 | 2007-09-12 | Abbott GmbH & Co. KG | Process for producing a solid dispersion of an active ingredient |
DK2004641T3 (da) | 2006-03-30 | 2011-01-24 | Tibotec Pharm Ltd | HIV-inhiberende 5-(hydroxymethylen og aminomethylen) substituerede pyrimidiner |
EP2004632B1 (en) | 2006-03-30 | 2014-03-12 | Janssen R&D Ireland | Hiv inhibiting 5-amido substituted pyrimidines |
CN101573342A (zh) | 2006-12-29 | 2009-11-04 | 泰博特克药品有限公司 | 抑制hiv的5,6-取代的嘧啶类化合物 |
JP5185283B2 (ja) | 2006-12-29 | 2013-04-17 | テイボテク・フアーマシユーチカルズ | Hiv阻害6−置換ピリミジン |
AU2009243139A1 (en) * | 2008-04-30 | 2009-11-05 | Novartis Ag | Continuous process for making pharmaceutical compositions |
BRPI0925048B8 (pt) | 2009-05-07 | 2021-06-22 | Gea Pharma Systems Ltd | módulo para produção de comprimidos e método para a produção contínua de comprimidos |
US20120148678A1 (en) | 2010-12-08 | 2012-06-14 | Advanced Technologies And Regenerative Medicine, Llc. | Sustained release of poorly water soluble active compounds |
US10532102B2 (en) | 2016-08-19 | 2020-01-14 | Foresee Pharmaceuticals Co., Ltd. | Pharmaceutical composition and methods of uses |
CN107441504A (zh) * | 2017-09-06 | 2017-12-08 | 广州中医药大学 | 番茄红素包合物及其制备方法及番茄红素包合物片剂、胶囊和颗粒 |
CN110898015A (zh) * | 2019-12-31 | 2020-03-24 | 上海汉维生物医药科技有限公司 | 一种伊曲康唑制剂的制备方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS61152765A (ja) * | 1984-12-27 | 1986-07-11 | Nippon Ekishiyou Kk | シクロデキストリン類で包接された化合物を含有した合成樹脂製品及びその製造方法 |
US5009900A (en) * | 1989-10-02 | 1991-04-23 | Nabisco Brands, Inc. | Glassy matrices containing volatile and/or labile components, and processes for preparation and use thereof |
ES2145063T3 (es) * | 1992-10-14 | 2000-07-01 | Nippon Shinyaku Co Ltd | Procedimiento de dislocacion del estado cristalino. |
AU5376994A (en) * | 1992-11-10 | 1994-06-08 | Nippon Shinyaku Co. Ltd. | Enclosure compound manufacturing method |
FR2705677B1 (fr) * | 1993-05-28 | 1995-08-11 | Roquette Freres | Micro-granules obtenus par extrusion-sphéronisation contenant une cyclodextrine. |
CZ154398A3 (cs) * | 1995-11-23 | 1998-08-12 | Janssen Pharmaceutica N.V. | Pevné směsi cyklodextrinů připravené vytlačováním taveniny |
KR100331529B1 (ko) | 1999-06-16 | 2002-04-06 | 민경윤 | 난용성 항진균제의 경구투여용 조성물 및 그의 제조 방법 |
-
1996
- 1996-11-20 CZ CZ981543A patent/CZ154398A3/cs unknown
- 1996-11-20 SK SK672-98A patent/SK67298A3/sk unknown
- 1996-11-20 BR BR9611562A patent/BR9611562A/pt not_active Application Discontinuation
- 1996-11-20 HU HU9900730A patent/HUP9900730A3/hu unknown
- 1996-11-20 WO PCT/EP1996/005118 patent/WO1997018839A1/en not_active Application Discontinuation
- 1996-11-20 EP EP96939864A patent/EP0862463A1/en not_active Withdrawn
- 1996-11-20 JP JP51939397A patent/JP3310299B2/ja not_active Expired - Fee Related
- 1996-11-20 IL IL12365496A patent/IL123654A/en not_active IP Right Cessation
- 1996-11-20 CN CNB961979348A patent/CN1198655C/zh not_active Expired - Fee Related
- 1996-11-20 NZ NZ322907A patent/NZ322907A/xx unknown
- 1996-11-20 PL PL96326161A patent/PL189122B1/pl not_active IP Right Cessation
- 1996-11-20 TR TR1998/00729T patent/TR199800729T2/xx unknown
- 1996-11-20 AU AU76943/96A patent/AU725204B2/en not_active Ceased
- 1996-11-22 ZA ZA9609831A patent/ZA969831B/xx unknown
-
1998
- 1998-03-11 NO NO981078A patent/NO981078L/no not_active Application Discontinuation
- 1998-05-20 US US09/081,808 patent/US6365188B1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
AU725204B2 (en) | 2000-10-05 |
SK67298A3 (en) | 1998-11-04 |
HUP9900730A3 (en) | 2001-04-28 |
CN1200677A (zh) | 1998-12-02 |
EP0862463A1 (en) | 1998-09-09 |
NO981078D0 (no) | 1998-03-11 |
BR9611562A (pt) | 1999-03-02 |
HUP9900730A2 (hu) | 1999-07-28 |
PL326161A1 (en) | 1998-08-31 |
CZ154398A3 (cs) | 1998-08-12 |
JPH11501050A (ja) | 1999-01-26 |
CN1198655C (zh) | 2005-04-27 |
US6365188B1 (en) | 2002-04-02 |
IL123654A0 (en) | 1998-10-30 |
IL123654A (en) | 2001-08-08 |
NO981078L (no) | 1998-05-22 |
PL189122B1 (pl) | 2005-06-30 |
TR199800729T2 (xx) | 1998-07-21 |
JP3310299B2 (ja) | 2002-08-05 |
WO1997018839A1 (en) | 1997-05-29 |
AU7694396A (en) | 1997-06-11 |
NZ322907A (en) | 1998-12-23 |
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