SK542007A3 - Substituované sulfónamidy, spôsob ich prípravy, farmaceutický prostriedok s ich obsahom a ich použitie - Google Patents

Substituované sulfónamidy, spôsob ich prípravy, farmaceutický prostriedok s ich obsahom a ich použitie Download PDF

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Publication number
SK542007A3
SK542007A3 SK54-2007A SK542007A SK542007A3 SK 542007 A3 SK542007 A3 SK 542007A3 SK 542007 A SK542007 A SK 542007A SK 542007 A3 SK542007 A3 SK 542007A3
Authority
SK
Slovakia
Prior art keywords
sulfamoyl
benzene
bis
benzamide
ethyl
Prior art date
Application number
SK54-2007A
Other languages
English (en)
Slovak (sk)
Inventor
Fridrich Greg��
Milan Remko
Elena Slu�Iakov�
Jarmila Knapikov�
Original Assignee
Unimed Pharma, Spol. S R. O.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Unimed Pharma, Spol. S R. O. filed Critical Unimed Pharma, Spol. S R. O.
Priority to SK54-2007A priority Critical patent/SK542007A3/sk
Priority to TW097108546A priority patent/TWI392492B/zh
Priority to ARP080101430A priority patent/AR065966A1/es
Priority to JOP/2008/0180A priority patent/JO3206B1/ar
Priority to UY31028A priority patent/UY31028A1/es
Priority to PE2008000680A priority patent/PE20090807A1/es
Priority to SI200831379T priority patent/SI2142499T1/sl
Priority to MX2009010528A priority patent/MX2009010528A/es
Priority to NZ581302A priority patent/NZ581302A/en
Priority to PT87419792T priority patent/PT2142499E/pt
Priority to RU2009134079/04A priority patent/RU2474574C2/ru
Priority to EP08741979.2A priority patent/EP2142499B1/en
Priority to CA2684591A priority patent/CA2684591C/en
Priority to UAA200910016A priority patent/UA99279C2/ru
Priority to CN200880012806A priority patent/CN101663267A/zh
Priority to AU2008241590A priority patent/AU2008241590B2/en
Priority to CL2008001109A priority patent/CL2008001109A1/es
Priority to JP2010504023A priority patent/JP5492764B2/ja
Priority to PCT/SK2008/050005 priority patent/WO2008130332A1/en
Priority to PL08741979T priority patent/PL2142499T3/pl
Priority to DK08741979.2T priority patent/DK2142499T3/en
Priority to BRPI0809728A priority patent/BRPI0809728A2/pt
Priority to ES08741979.2T priority patent/ES2528284T3/es
Priority to HUE08741979A priority patent/HUE024552T2/hu
Priority to SA08290238A priority patent/SA08290238B1/ar
Priority to US12/596,820 priority patent/US8193184B2/en
Publication of SK542007A3 publication Critical patent/SK542007A3/sk
Priority to ZA200906305A priority patent/ZA200906305B/xx
Priority to IL200952A priority patent/IL200952A0/en
Priority to TNP2009000421A priority patent/TN2009000421A1/fr
Priority to MA32329A priority patent/MA31364B1/ar
Priority to HRP20141246AT priority patent/HRP20141246T1/hr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
    • C07C311/17—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
    • C07C311/18—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by nitrogen atoms, not being part of nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • AIDS & HIV (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SK54-2007A 2007-04-20 2007-04-20 Substituované sulfónamidy, spôsob ich prípravy, farmaceutický prostriedok s ich obsahom a ich použitie SK542007A3 (sk)

Priority Applications (31)

Application Number Priority Date Filing Date Title
SK54-2007A SK542007A3 (sk) 2007-04-20 2007-04-20 Substituované sulfónamidy, spôsob ich prípravy, farmaceutický prostriedok s ich obsahom a ich použitie
TW097108546A TWI392492B (zh) 2007-04-20 2008-03-11 經取代磺醯胺，其製法，包括該經取代磺醯胺之組成物及其用途
ARP080101430A AR065966A1 (es) 2007-04-20 2008-04-04 Sulfonamidas substituidas, proceso para su preparacion, composicion farmaceutica de las mismas y su uso
JOP/2008/0180A JO3206B1 (ar) 2007-04-20 2008-04-17 سلفوناميدات مستبدلة وعملية لتحضيرها وتركيب صيدلى يشتمل عليها واستعمالها في علاج الجلوكوما
UY31028A UY31028A1 (es) 2007-04-20 2008-04-17 Sulfonamidas substituidas, proceso para su preparacion, composicion farmaceutica de las mismas y su uso.
AU2008241590A AU2008241590B2 (en) 2007-04-20 2008-04-18 Substituted sulphonamides, process for their preparation, pharmaceutical composition comprising thereof and their use
PCT/SK2008/050005 WO2008130332A1 (en) 2007-04-20 2008-04-18 Subsituted sulphonamides, process for their preparation, pharmaceutical composition comprising thereof and their use
MX2009010528A MX2009010528A (es) 2007-04-20 2008-04-18 Sulfonamidas sustituidas, procedimiento para su preparacion, composicion farmaceutica que comprende las mismas y su uso.
NZ581302A NZ581302A (en) 2007-04-20 2008-04-18 Subsituted sulphonamides, process for their preparation, pharmaceutical composition comprising thereof and their use in treating glaucoma
PT87419792T PT2142499E (pt) 2007-04-20 2008-04-18 Sulfonamidas substituídas, processo para a sua preparação, composição farmacêutica compreendendo-as e sua utilização para o tratamento de glaucoma
RU2009134079/04A RU2474574C2 (ru) 2007-04-20 2008-04-18 Замещенные сульфонамиды, способ их получения, лекарственные препараты, которые их содержат, и их использование
EP08741979.2A EP2142499B1 (en) 2007-04-20 2008-04-18 Substituted sulphonamides, process for their preparation, pharmaceutical composition comprising thereof and their use for treating glaucoma
CA2684591A CA2684591C (en) 2007-04-20 2008-04-18 Subsituted sulphonamides, process for their preparation, pharmaceutical composition comprising thereof and their use
UAA200910016A UA99279C2 (ru) 2007-04-20 2008-04-18 Замещенные сульфонамиды, способ их получения, фармацевтическая композиция, которая их содержит, и их применение
CN200880012806A CN101663267A (zh) 2007-04-20 2008-04-18 取代的磺酰胺、其制备方法、包含其的药物组合物及其应用
PE2008000680A PE20090807A1 (es) 2007-04-20 2008-04-18 Sulfonamidas substituidas, proceso para su preparacion y composicion farmaceutica de las mismas
CL2008001109A CL2008001109A1 (es) 2007-04-20 2008-04-18 Compuestos derivados de sulfonamidas; procedimiento de preparacion; composicion farmaceutica que comprende a dichos compuestos; y su uso para el tratamiento del glaucoma.
JP2010504023A JP5492764B2 (ja) 2007-04-20 2008-04-18 置換スルホンアミド、その製造方法、それを含有する製薬組成物及びその使用
SI200831379T SI2142499T1 (sl) 2007-04-20 2008-04-18 Substituirani sulfonamidi, postopek priprave le-teh, farmacevtski sestavek, vsebujoč le-te ter njihova uporaba za zdravljenje glavkoma
PL08741979T PL2142499T3 (pl) 2007-04-20 2008-04-18 Podstawione sulfonamidy, sposób ich wytwarzania, zawierająca je kompozycja farmaceutyczna oraz ich zastosowanie do leczenia jaskry
DK08741979.2T DK2142499T3 (en) 2007-04-20 2008-04-18 Substituted sulphonamides, process for their preparation, pharmaceutical composition comprising thereof and their use for the treatment of glaucoma
BRPI0809728A BRPI0809728A2 (pt) 2007-04-20 2008-04-18 "sulfonamidas substituídas, processo de preparação, composição farmacêutica que as compõem, assim como seu uso."
ES08741979.2T ES2528284T3 (es) 2007-04-20 2008-04-18 Sulfonamidas sustituidas, procedimiento para su preparación, composición farmacéutica que las contiene y su uso para tratar el glaucoma
HUE08741979A HUE024552T2 (hu) 2007-04-20 2008-04-18 Helyettesített szulfonamidok, eljárás elõállításukra, ezeket tartalmazó gyógyszerkészítmények és alkalmazásuk glaucoma kezelésére
SA08290238A SA08290238B1 (ar) 2007-04-20 2008-04-19 استخدام سلفونات أميد مستبدلة وعملية لتحضيرها وتركيبة دوائية تشملها
US12/596,820 US8193184B2 (en) 2007-04-20 2008-04-20 Substituted sulphonamides, process for their preparation, pharmaceutical composition comprising thereof and their use
ZA200906305A ZA200906305B (en) 2007-04-20 2009-09-10 Substituted sulphonamides, process for their preparation, pharmaceutical composition comprising thereof and their use
IL200952A IL200952A0 (en) 2007-04-20 2009-09-15 Substituted sulphonamides, process for their preparation, pharmaceutical composition comprising thereof and their use
TNP2009000421A TN2009000421A1 (en) 2007-04-20 2009-10-13 Substituted sulphonamides, process for their preparation, pharmaceutical composition comprising thereof and their use
MA32329A MA31364B1 (ar) 2007-04-20 2009-11-05 السولفاميد المبدل، عملية إعداده، التركيب الدوائي المحتوي عليه واستخدامه.
HRP20141246AT HRP20141246T1 (hr) 2007-04-20 2014-12-22 Supstituirani sulfonamidi, postupak za njihovu pripremu, farmaceutski sastavi koji ih sadrže i njihova upotreba za lijeäśenje glaukoma

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SK54-2007A SK542007A3 (sk) 2007-04-20 2007-04-20 Substituované sulfónamidy, spôsob ich prípravy, farmaceutický prostriedok s ich obsahom a ich použitie

Publications (1)

Publication Number Publication Date
SK542007A3 true SK542007A3 (sk) 2008-11-06

Family

ID=39671772

Family Applications (1)

Application Number Title Priority Date Filing Date
SK54-2007A SK542007A3 (sk) 2007-04-20 2007-04-20 Substituované sulfónamidy, spôsob ich prípravy, farmaceutický prostriedok s ich obsahom a ich použitie

Country Status (31)

Country Link
US (1) US8193184B2 (ar)
EP (1) EP2142499B1 (ar)
JP (1) JP5492764B2 (ar)
CN (1) CN101663267A (ar)
AR (1) AR065966A1 (ar)
AU (1) AU2008241590B2 (ar)
BR (1) BRPI0809728A2 (ar)
CA (1) CA2684591C (ar)
CL (1) CL2008001109A1 (ar)
DK (1) DK2142499T3 (ar)
ES (1) ES2528284T3 (ar)
HR (1) HRP20141246T1 (ar)
HU (1) HUE024552T2 (ar)
IL (1) IL200952A0 (ar)
JO (1) JO3206B1 (ar)
MA (1) MA31364B1 (ar)
MX (1) MX2009010528A (ar)
NZ (1) NZ581302A (ar)
PE (1) PE20090807A1 (ar)
PL (1) PL2142499T3 (ar)
PT (1) PT2142499E (ar)
RU (1) RU2474574C2 (ar)
SA (1) SA08290238B1 (ar)
SI (1) SI2142499T1 (ar)
SK (1) SK542007A3 (ar)
TN (1) TN2009000421A1 (ar)
TW (1) TWI392492B (ar)
UA (1) UA99279C2 (ar)
UY (1) UY31028A1 (ar)
WO (1) WO2008130332A1 (ar)
ZA (1) ZA200906305B (ar)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115141128A (zh) * 2022-06-24 2022-10-04 沈阳药科大学 3-芳基-3-(磺胺苯甲酰胺基)丙(烯)酸衍生物及其制备方法及应用

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US2789938A (en) 1952-11-24 1957-04-23 Merck & Co Inc Method of producing a diuretic effect with p-carboxybenzenesulfonamide
CH451142A (de) * 1965-01-19 1968-05-15 Sandoz Ag Verfahren zur Herstellung neuer basisch substituierter Benzoesäureamide
GB1523631A (en) * 1975-07-08 1978-09-06 Leo Pharm Prod Ltd Sulphonamide derivatives
EP0029090A3 (en) * 1979-09-28 1981-07-01 American Cyanamid Company Sulfon amides containing a hindered phenol; stabilized composition containing a synthetic polymer and said sulfon amides
FR2504528A1 (fr) * 1981-04-23 1982-10-29 Choay Sa Dialcoxy (2,4) benzenesulfonamides n-substitues
JPS5939867A (ja) * 1982-08-27 1984-03-05 Fuji Yakuhin Kogyo Kk ２−クロロスルホニル−４−ｎ−置換スルフアミル−クロロベンゼンの製造法
JPS6041071B2 (ja) * 1983-07-28 1985-09-13 ソシエテ・デチユ−デ・シヤンテイフイツク・エ・アンデユストリエル・ドウ・リル−ドウ−フランス 安息香酸誘導体
US4678855A (en) * 1985-10-09 1987-07-07 Merck & Co., Inc. Substituted benzenesulfonamides
US4721809A (en) * 1986-09-18 1988-01-26 American Home Products Corporation Alkylsulfonamido or perfluoroalkylsulfonamido benzenesulfonamides
AU690656B2 (en) * 1994-03-11 1998-04-30 Pharmacopeia Drug Discovery, Inc. Sulfonamide derivatives and their use
JP2001162950A (ja) * 1999-12-13 2001-06-19 Fuji Photo Film Co Ltd 感熱記録材料
JP4139712B2 (ja) * 2002-03-14 2008-08-27 ライオン株式会社 漂白活性化剤及び漂白剤組成物
US7922702B2 (en) * 2004-07-02 2011-04-12 Qlt Inc. Treatment medium delivery device and methods for delivery of such treatment mediums to the eye using such a delivery device
SE0401969D0 (sv) * 2004-08-02 2004-08-02 Astrazeneca Ab Piperidine derivatives
WO2008071421A1 (en) * 2006-12-15 2008-06-19 Nicox S.A. Nitrate esters of carbonic anhydrase inhibitors

Also Published As

Publication number Publication date
ES2528284T3 (es) 2015-02-06
PL2142499T3 (pl) 2015-05-29
BRPI0809728A2 (pt) 2016-10-18
CL2008001109A1 (es) 2008-11-03
TW200843730A (en) 2008-11-16
AU2008241590B2 (en) 2012-06-21
HUE024552T2 (hu) 2016-02-29
RU2474574C2 (ru) 2013-02-10
UA99279C2 (ru) 2012-08-10
US20100125076A1 (en) 2010-05-20
CA2684591A1 (en) 2008-10-30
NZ581302A (en) 2012-03-30
TWI392492B (zh) 2013-04-11
JO3206B1 (ar) 2018-03-08
AR065966A1 (es) 2009-07-15
EP2142499B1 (en) 2014-12-10
UY31028A1 (es) 2008-11-28
TN2009000421A1 (en) 2011-03-31
IL200952A0 (en) 2010-05-17
SI2142499T1 (sl) 2015-04-30
RU2009134079A (ru) 2011-05-27
JP5492764B2 (ja) 2014-05-14
JP2010524929A (ja) 2010-07-22
DK2142499T3 (en) 2015-01-12
HRP20141246T1 (hr) 2015-02-13
WO2008130332B1 (en) 2008-12-18
US8193184B2 (en) 2012-06-05
CA2684591C (en) 2016-11-01
SA08290238B1 (ar) 2012-06-23
MA31364B1 (ar) 2010-05-03
CN101663267A (zh) 2010-03-03
AU2008241590A1 (en) 2008-10-30
ZA200906305B (en) 2010-05-26
MX2009010528A (es) 2011-01-28
PT2142499E (pt) 2015-02-09
EP2142499A1 (en) 2010-01-13
WO2008130332A1 (en) 2008-10-30
PE20090807A1 (es) 2009-07-20

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