SK288053B6 - Combination comprising 5-[4-[2-(N-methyl-N-(2- pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione and sub maximal amount of sulphonylurea - Google Patents

Combination comprising 5-[4-[2-(N-methyl-N-(2- pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione and sub maximal amount of sulphonylurea Download PDF

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Publication number
SK288053B6
SK288053B6 SK89-2005A SK892005A SK288053B6 SK 288053 B6 SK288053 B6 SK 288053B6 SK 892005 A SK892005 A SK 892005A SK 288053 B6 SK288053 B6 SK 288053B6
Authority
SK
Slovakia
Prior art keywords
dione
pyridyl
ethoxy
benzyl
methyl
Prior art date
Application number
SK89-2005A
Other languages
English (en)
Slovak (sk)
Inventor
Robin Edwin Buckingham
Stephen Alistair Smith
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10816177&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SK288053(B6) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of SK288053B6 publication Critical patent/SK288053B6/sk

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
SK89-2005A 1997-07-18 1998-07-16 Combination comprising 5-[4-[2-(N-methyl-N-(2- pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione and sub maximal amount of sulphonylurea SK288053B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9715306A GB9715306D0 (en) 1997-07-18 1997-07-18 Novel method of treatment
PCT/GB1998/002109 WO1999003476A1 (en) 1997-07-18 1998-07-16 Treatment of diabetes with thiazolidinedione and sulphonylurea

Publications (1)

Publication Number Publication Date
SK288053B6 true SK288053B6 (sk) 2013-03-01

Family

ID=10816177

Family Applications (2)

Application Number Title Priority Date Filing Date
SK60-2000A SK287823B6 (sk) 1997-07-18 1998-07-16 Pharmaceutical composition comprising 2 to 8 mg of 5-[4-[2-(N-2- methyl-N-pyridyl)amino)ethoxy]benzyl]tiazolidin-2,4-dione and sub-maximal amount of glimepiride and use thereof
SK89-2005A SK288053B6 (sk) 1997-07-18 1998-07-16 Combination comprising 5-[4-[2-(N-methyl-N-(2- pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione and sub maximal amount of sulphonylurea

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SK60-2000A SK287823B6 (sk) 1997-07-18 1998-07-16 Pharmaceutical composition comprising 2 to 8 mg of 5-[4-[2-(N-2- methyl-N-pyridyl)amino)ethoxy]benzyl]tiazolidin-2,4-dione and sub-maximal amount of glimepiride and use thereof

Country Status (41)

Country Link
EP (1) EP0998291B2 (ko)
JP (2) JP2001510158A (ko)
KR (1) KR100680667B1 (ko)
CN (1) CN1264302A (ko)
AP (1) AP1318A (ko)
AR (2) AR016768A1 (ko)
AT (1) ATE366577T1 (ko)
AU (1) AU743269B2 (ko)
BG (1) BG64892B1 (ko)
BR (1) BR9810904A (ko)
CA (1) CA2297115C (ko)
CO (1) CO4940422A1 (ko)
CY (1) CY1107745T1 (ko)
CZ (1) CZ302668B6 (ko)
DE (1) DE69838066T3 (ko)
DK (1) DK0998291T4 (ko)
DZ (1) DZ2564A1 (ko)
EA (1) EA003303B1 (ko)
ES (1) ES2290989T5 (ko)
GB (1) GB9715306D0 (ko)
HK (1) HK1029272A1 (ko)
HU (1) HU229119B1 (ko)
ID (1) ID24198A (ko)
IL (1) IL134045A0 (ko)
IN (1) IN189035B (ko)
MA (1) MA26522A1 (ko)
MY (1) MY138246A (ko)
NO (1) NO326356B1 (ko)
NZ (3) NZ515555A (ko)
OA (1) OA11632A (ko)
PE (1) PE99799A1 (ko)
PL (2) PL338127A1 (ko)
PT (1) PT998291E (ko)
SI (1) SI0998291T2 (ko)
SK (2) SK287823B6 (ko)
TR (1) TR200000135T2 (ko)
TW (1) TW586926B (ko)
UA (1) UA70302C2 (ko)
UY (1) UY25103A1 (ko)
WO (1) WO1999003476A1 (ko)
ZA (1) ZA986365B (ko)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1832291A3 (en) * 1999-07-13 2009-11-04 Medicure Inc. use of pyridoxal phosphate for the treatment of diabetes and related complications
EP1897547A1 (en) * 1999-07-13 2008-03-12 Medicure Inc. Use of pyridoxal phosphate derivatives for the treatment of diabetes and related complications
US6586438B2 (en) 1999-11-03 2003-07-01 Bristol-Myers Squibb Co. Antidiabetic formulation and method
US20010036479A1 (en) 2000-01-14 2001-11-01 Gillian Cave Glyburide composition
WO2002055009A1 (en) 2001-01-12 2002-07-18 Sun Pharmaceutical Industries Limited Spaced drug delivery system
NZ546337A (en) 2003-10-31 2009-03-31 Takeda Pharmaceutical Solid preparation comprising an insulin sensitizer such as pioglitazone hydrochloride, an insulin secretagogue such as glimepiride and a polyoxyethylene sorbitan fatty acid ester such as Polysorbate 80
JP2008019169A (ja) * 2004-10-25 2008-01-31 Osaka Univ 新規ｐｐａｒ調節剤およびそのスクリーニング方法
ES2576258T3 (es) 2005-12-22 2016-07-06 Takeda Pharmaceutical Company Limited Preparación sólida que contiene un sensibilizador de insulina

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5522636A (en) * 1978-08-04 1980-02-18 Takeda Chem Ind Ltd Thiazoliding derivative
JPS5697277A (en) * 1980-01-07 1981-08-05 Takeda Chem Ind Ltd Thiazolidine derivative
JPS6051189A (ja) * 1983-08-30 1985-03-22 Sankyo Co Ltd チアゾリジン誘導体およびその製造法
US4582839A (en) * 1984-03-21 1986-04-15 Takeda Chemical Industries, Ltd. 2,4-thiazolidinediones
CN1003445B (zh) * 1984-10-03 1989-03-01 武田药品工业株式会社 噻唑烷二酮衍生物，其制备方法和用途
JPH06779B2 (ja) * 1985-06-10 1994-01-05 武田薬品工業株式会社 チアゾリジオン誘導体およびそれを含んでなる医薬組成物
US4812570A (en) * 1986-07-24 1989-03-14 Takeda Chemical Industries, Ltd. Method for producing thiazolidinedione derivatives
ATE186724T1 (de) * 1987-09-04 1999-12-15 Beecham Group Plc Substituierte thiazolidindionderivate
US4791125A (en) * 1987-12-02 1988-12-13 Pfizer Inc. Thiazolidinediones as hypoglycemic and anti-atherosclerosis agents
WO1989008651A1 (en) * 1988-03-08 1989-09-21 Pfizer Inc. Hypoglycemic thiazolidinedione derivatives
US5061717A (en) * 1988-03-08 1991-10-29 Pfizer Inc. Thiazolidinedione hypoglycemic agents
WO1991007107A1 (en) * 1989-11-13 1991-05-30 Pfizer Inc. Oxazolidinedione hypoglycemic agents
JPH04210683A (ja) * 1990-12-06 1992-07-31 Terumo Corp チアゾリジン−２，４−ジオン誘導体およびこれを含有する糖尿病合併症治療薬
US5183823A (en) * 1991-04-11 1993-02-02 Takeda Chemical Industries, Ltd. Pyridine n-oxide compounds which are useful as hypoglycemic and hypolipidemic agents
ES2089474T3 (es) * 1991-08-16 1996-10-01 Sandoz Ltd Inhalador para la administracion de sustancias en polvo.
US5900435A (en) * 1991-08-26 1999-05-04 Pharmacia & Upjohn Company Composition, food product and uses of 3-guanidinopropionic acid
GB9218830D0 (en) * 1992-09-05 1992-10-21 Smithkline Beecham Plc Novel compounds
TW438587B (en) * 1995-06-20 2001-06-07 Takeda Chemical Industries Ltd A pharmaceutical composition for prophylaxis and treatment of diabetes
US5859037A (en) * 1997-02-19 1999-01-12 Warner-Lambert Company Sulfonylurea-glitazone combinations for diabetes

Also Published As

Publication number Publication date
DK0998291T3 (da) 2007-11-05
DZ2564A1 (fr) 2003-02-15
PE99799A1 (es) 1999-12-22
EP0998291B1 (en) 2007-07-11
SI0998291T2 (sl) 2011-10-28
CZ2000173A3 (en) 2001-05-16
TW586926B (en) 2004-05-11
DE69838066T2 (de) 2008-03-20
EA003303B1 (ru) 2003-04-24
DK0998291T4 (da) 2011-09-26
ATE366577T1 (de) 2007-08-15
SK602000A3 (en) 2000-07-11
GB9715306D0 (en) 1997-09-24
HUP0003634A2 (hu) 2001-07-30
AU8448798A (en) 1999-02-10
AR016768A1 (es) 2001-08-01
UY25103A1 (es) 2000-12-29
PL199125B1 (pl) 2008-08-29
NO20000229L (no) 2000-01-17
AP2000001734A0 (en) 2000-03-31
ID24198A (id) 2000-07-13
AP1318A (en) 2004-10-22
AR019331A2 (es) 2002-02-13
NZ501256A (en) 2002-09-27
CO4940422A1 (es) 2000-07-24
SK287823B6 (sk) 2011-11-04
EA200000141A1 (ru) 2000-08-28
HUP0003634A3 (en) 2003-04-28
CA2297115C (en) 2010-02-23
DE69838066T3 (de) 2012-03-29
DE69838066D1 (de) 2007-08-23
PL338127A1 (en) 2000-09-25
WO1999003476A1 (en) 1999-01-28
ES2290989T5 (es) 2011-11-11
BG64892B1 (bg) 2006-08-31
TR200000135T2 (tr) 2000-05-22
EP0998291B2 (en) 2011-07-06
IL134045A0 (en) 2001-04-30
NO326356B1 (no) 2008-11-17
MA26522A1 (fr) 2004-12-20
CA2297115A1 (en) 1999-01-28
IN189035B (ko) 2002-12-07
AU743269B2 (en) 2002-01-24
BR9810904A (pt) 2000-09-26
CN1264302A (zh) 2000-08-23
KR20010021948A (ko) 2001-03-15
NO20000229D0 (no) 2000-01-17
CZ302668B6 (cs) 2011-08-24
EP0998291A1 (en) 2000-05-10
CY1107745T1 (el) 2013-04-18
ES2290989T3 (es) 2008-02-16
JP2001510158A (ja) 2001-07-31
SI0998291T1 (sl) 2007-12-31
OA11632A (en) 2004-11-22
NZ520652A (en) 2004-06-25
KR100680667B1 (ko) 2007-02-09
UA70302C2 (uk) 2004-10-15
NZ515555A (en) 2002-09-27
HU229119B1 (en) 2013-08-28
PT998291E (pt) 2007-10-11
JP2005247865A (ja) 2005-09-15
HK1029272A1 (en) 2001-03-30
ZA986365B (en) 2000-01-17
MY138246A (en) 2009-05-29
BG104139A (en) 2000-11-30

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MK4A Patent expired

Expiry date: 20180716