SK286103B6 - Farmaceutický prostriedok na liečenie respiračných a kožných ochorení s obsahom aspoň jedného antagonistu leukotriénu a aspoň jedného antihistaminikaa jeho použitie - Google Patents
Farmaceutický prostriedok na liečenie respiračných a kožných ochorení s obsahom aspoň jedného antagonistu leukotriénu a aspoň jedného antihistaminikaa jeho použitie Download PDFInfo
- Publication number
- SK286103B6 SK286103B6 SK897-2000A SK8972000A SK286103B6 SK 286103 B6 SK286103 B6 SK 286103B6 SK 8972000 A SK8972000 A SK 8972000A SK 286103 B6 SK286103 B6 SK 286103B6
- Authority
- SK
- Slovakia
- Prior art keywords
- pharmaceutical composition
- pharmaceutically acceptable
- acceptable salt
- antihistamine
- montelukast
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/10—Expectorants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/12—Mucolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6863897P | 1997-12-23 | 1997-12-23 | |
| US7863898P | 1998-03-19 | 1998-03-19 | |
| PCT/US1998/026223 WO1999032125A1 (en) | 1997-12-23 | 1998-12-21 | Composition for treating respiratory and skin diseases, comprising at least one leukotriene antagonist and at least one antihistamine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SK8972000A3 SK8972000A3 (en) | 2001-02-12 |
| SK286103B6 true SK286103B6 (sk) | 2008-03-05 |
Family
ID=26749192
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK897-2000A SK286103B6 (sk) | 1997-12-23 | 1998-12-21 | Farmaceutický prostriedok na liečenie respiračných a kožných ochorení s obsahom aspoň jedného antagonistu leukotriénu a aspoň jedného antihistaminikaa jeho použitie |
Country Status (27)
| Country | Link |
|---|---|
| EP (1) | EP1041990B1 (pt) |
| JP (2) | JP2001526232A (pt) |
| KR (1) | KR100737710B1 (pt) |
| CN (1) | CN1283115A (pt) |
| AR (1) | AR017224A1 (pt) |
| AT (1) | ATE331522T1 (pt) |
| AU (1) | AU758771B2 (pt) |
| BR (1) | BR9814417A (pt) |
| CA (1) | CA2315721C (pt) |
| CO (1) | CO4980868A1 (pt) |
| CZ (1) | CZ301349B6 (pt) |
| DE (1) | DE69835103T2 (pt) |
| DK (1) | DK1041990T3 (pt) |
| ES (1) | ES2263229T3 (pt) |
| HK (1) | HK1027502A1 (pt) |
| HU (1) | HUP0101369A3 (pt) |
| ID (1) | ID26390A (pt) |
| IL (1) | IL136461A0 (pt) |
| MY (1) | MY121744A (pt) |
| NO (1) | NO20003288L (pt) |
| NZ (1) | NZ520907A (pt) |
| PE (1) | PE20000126A1 (pt) |
| PL (1) | PL193131B1 (pt) |
| PT (1) | PT1041990E (pt) |
| SA (1) | SA99200013B1 (pt) |
| SK (1) | SK286103B6 (pt) |
| WO (1) | WO1999032125A1 (pt) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6303632B1 (en) | 1992-09-03 | 2001-10-16 | Sepracor Inc. | Compositions for treating allergic and other disorders using norastemizole in combination with other active ingredients |
| ES2210957T3 (es) | 1992-09-03 | 2004-07-01 | Sepracor Inc. | Composiciones farmaceuticas que contienen norastemizol. |
| US7214683B1 (en) | 1994-12-30 | 2007-05-08 | Sepracor Inc. | Compositions of descarboethoxyloratadine |
| US7211582B1 (en) | 1994-12-30 | 2007-05-01 | Sepracor Inc. | Methods for treating urticaria using descarboethoxyloratadine |
| US6384038B1 (en) * | 1998-04-14 | 2002-05-07 | Sepracor Inc. | Methods and compositions using cetirizine in combination with leukotriene inhibitors or decongestants |
| US6194431B1 (en) | 1998-04-14 | 2001-02-27 | Paul D. Rubin | Methods and compositions using terfenadine metabolites in combination with leukotriene inhibitors |
| US6248308B1 (en) | 1998-04-14 | 2001-06-19 | Sepracor Inc. | Methods of using norastemizole in combination with leukotriene inhibitors to treat or prevent asthma |
| IT1303671B1 (it) | 1998-07-28 | 2001-02-23 | Nicox Sa | Sali dell'acido nitrico con farmaci attivi nel trattamento dipatologie del sistema respiratorio |
| EP1000623A1 (en) * | 1998-09-29 | 2000-05-17 | BOEHRINGER INGELHEIM INTERNATIONAL GmbH | Use of epinastine as antitussivum |
| WO2000018399A1 (en) * | 1998-09-30 | 2000-04-06 | Ono Pharmaceutical Co., Ltd. | Preventive and/or therapeutic agents for sinusitis______________ |
| US20020198246A1 (en) | 1998-09-30 | 2002-12-26 | Ono Pharmaceutical Co., Ltd. | Agent for preventing and/or treating sinusitis |
| US7405223B2 (en) | 2000-02-03 | 2008-07-29 | Schering Corporation | Treating allergic and inflammatory conditions |
| AR028502A1 (es) * | 2000-02-03 | 2003-05-14 | Schering Corp | Tratamiento de condiciones inflamatorias alérgicas |
| DE10007203A1 (de) * | 2000-02-17 | 2001-08-23 | Asta Medica Ag | Neue Kombination nichtsedierender Antihistaminika mit Substanzen, die die Leukotrienwirkung beeinflussen, zur Behandlung der Rhinitis/Konjunktivitis |
| JP2002087963A (ja) * | 2000-09-08 | 2002-03-27 | Nippon Boehringer Ingelheim Co Ltd | 直接打錠により製造されたエピナスチン含有錠剤 |
| US20020094345A1 (en) | 2000-10-06 | 2002-07-18 | Sara Abelaira | Pharmaceutical compositions containing epinastine and pseudoephedrine |
| PE20020324A1 (es) * | 2000-10-06 | 2002-06-18 | Boehringer Ingelheim Int | Nuevas composiciones farmaceuticas que contienen epinastina y pseudoefedrina |
| JP4074427B2 (ja) * | 2000-12-18 | 2008-04-09 | 株式会社栃木臨床病理研究所 | 子宮内膜症の予防又は治療薬 |
| US20020198228A1 (en) * | 2001-04-03 | 2002-12-26 | Kaura Sita R. | Composition and method for the treatment of respiratory desease |
| GB0115181D0 (en) * | 2001-06-20 | 2001-08-15 | Glaxo Group Ltd | Novel use |
| CN1518448A (zh) * | 2001-06-20 | 2004-08-04 | ���鹫˾ | 用于治疗鼻充血和鼻塞的抗组胺剂 |
| IL159287A0 (en) | 2001-06-28 | 2004-06-01 | Ucb Farchim Sa | Tablet comprising cetirizine and pseudoephedrine |
| MY148466A (en) | 2001-10-26 | 2013-04-30 | Merck Frosst Canada Ltd | Granule formulation |
| WO2003101434A2 (en) * | 2001-12-21 | 2003-12-11 | Sampad Bhattacharya | Intranasal pharmaceutical compositions comprising an antihistamine and a leukotriene inhibitor |
| BR0306329A (pt) * | 2002-05-29 | 2005-04-26 | Aventis Pharmaceuticals Holdin | Método de tratamento de asma |
| ATE386526T1 (de) * | 2002-07-02 | 2008-03-15 | Ucb Farchim Sa | Diarylmethylpiperazines als prophylaktische oder therapeutische mittel gegen virale myocarditis |
| JP2006510639A (ja) * | 2002-12-06 | 2006-03-30 | ユセベ ファルシム ソシエテ アノニム | エフレチリジン及びプソイドエフェドリンを含む錠剤 |
| WO2004087095A2 (es) * | 2003-03-31 | 2004-10-14 | Osmotica Costa Rica, Sociedad Anonima | Dispositivo osmótico que contiene zafirlukast y un antagonista h1 |
| EP1468696A1 (en) * | 2003-04-17 | 2004-10-20 | Boehringer Ingelheim International GmbH | Combinations of epinastine and antiphlogisitcs as new pharmaceutical compositions for the treatment of skin diseases |
| WO2005030331A1 (en) * | 2003-09-26 | 2005-04-07 | Fairfield Clinical Trials, Llc | Combination antihistamine medication |
| EP1735001A2 (en) * | 2004-03-24 | 2006-12-27 | Boehringer Ingelheim International Gmbh | Pharmaceutical compositions for the treatment of skin diseases comprising a combination of epinastine and one or more additional minerals or one or more crude drugs |
| TR200806298A2 (tr) | 2008-08-22 | 2010-03-22 | Bi̇lgi̇ç Mahmut | Farmasötik formülasyon |
| US9044479B2 (en) | 2010-06-16 | 2015-06-02 | Bruce Chandler May | Use of levocetirizine and montelukast in the treatment of influenza, common cold and inflammation |
| WO2012150707A1 (ja) * | 2011-05-02 | 2012-11-08 | 国立大学法人熊本大学 | 幹細胞からインスリン産生細胞への分化誘導を促進する低分子化合物および該化合物を用いた幹細胞からインスリン産生細胞への分化誘導方法 |
| KR20130009553A (ko) * | 2011-07-15 | 2013-01-23 | 한미약품 주식회사 | 몬테루카스트 또는 이의 약학적으로 허용가능한 염 및 레보세티리진 또는 이의 약학적으로 허용가능한 염을 함유하는 캡슐 제제 |
| WO2013058527A2 (ko) * | 2011-10-18 | 2013-04-25 | 주식회사 네비팜 | 류코트리엔 길항제와 에피나스틴의 복합제제 |
| KR101278572B1 (ko) * | 2011-10-18 | 2013-06-25 | 주식회사 네비팜 | 류코트리엔 길항제와 에피나스틴의 복합제제 |
| ES2745041T3 (es) | 2013-03-13 | 2020-02-27 | Inflammatory Response Res Inc | Uso de levocetirizina y montelukast en el tratamiento de trastornos autoinmunitarios |
| AU2014249534B2 (en) | 2013-03-13 | 2018-08-30 | IRR, Inc. | Use of levocetirizine and montelukast in the treatment of vasculitis |
| ES2660494T3 (es) | 2013-03-13 | 2018-03-22 | 14779507 | Uso de levocetirizina y montelukast en el tratamiento de una lesión traumática |
| US9636318B2 (en) * | 2015-08-31 | 2017-05-02 | Banner Life Sciences Llc | Fumarate ester dosage forms |
| KR102356601B1 (ko) | 2014-06-10 | 2022-01-27 | 지엘팜텍주식회사 | 슈도에페드린을 함유하는 방출조절 펠렛 조성물 |
| EP3193875B1 (en) | 2014-09-15 | 2022-02-16 | Inflammatory Response Research, Inc. | Levocetirizine and montelukast in the treatment of inflammation mediated conditions |
| US9981039B2 (en) | 2015-05-29 | 2018-05-29 | Accolade Pharma Llc | Composition, its preparation and method of use in treating skin disorders |
| RU2018143562A (ru) * | 2016-05-17 | 2020-06-17 | Пропонент Байотек Гмбх | Карбоновые кислоты, предназначенные для лечения/предупреждения заболевания кожи |
| BR112018072177A2 (pt) * | 2016-05-17 | 2019-02-12 | Proponent Biotech Gmbh | composição farmacêutica, recipiente, e, métodos para tratar e prevenir congestão nasal, infecções virais do trato respiratório e/ou inflamação da garganta |
| WO2021142062A1 (en) | 2020-01-10 | 2021-07-15 | Banner Life Sciences Llc | Fumarate ester dosage forms with enhanced gastrointestinal tolerability |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4254129A (en) * | 1979-04-10 | 1981-03-03 | Richardson-Merrell Inc. | Piperidine derivatives |
| US4662880A (en) * | 1986-03-14 | 1987-05-05 | Alza Corporation | Pseudoephedrine, brompheniramine therapy |
| US4810502A (en) * | 1987-02-27 | 1989-03-07 | Alza Corporation | Pseudoephedrine brompheniramine therapy |
| US5276044A (en) * | 1991-08-14 | 1994-01-04 | Allergan, Inc. | Leukotriene receptor antagonist and antihistamine complex pharmaceutical compositions |
| DE4203201A1 (de) * | 1992-02-05 | 1993-08-12 | Boehringer Ingelheim Kg | Neue amidinderivate, ihre herstellung und verwendung |
| DK0902013T3 (da) * | 1992-02-05 | 2002-03-25 | Boehringer Ingelheim Pharma | Hidtil ukendte amidinderivater, deres fremstilling og anvendelse som lægemidler med LTB4-antagonistisk virkning |
| US5270324A (en) * | 1992-04-10 | 1993-12-14 | Merck Frosst Canada, Inc. | Fluorinated hydroxyalkylquinoline acids as leukotriene antagonists |
| US5595997A (en) * | 1994-12-30 | 1997-01-21 | Sepracor Inc. | Methods and compositions for treating allergic rhinitis and other disorders using descarboethoxyloratadine |
| JPH08325265A (ja) * | 1995-05-29 | 1996-12-10 | Fujisawa Pharmaceut Co Ltd | チアゾリルベンゾフラン誘導体の製造方法、および該製造方法に用いられる化合物 |
| EP0780127A1 (en) * | 1995-12-19 | 1997-06-25 | The Procter & Gamble Company | A nasal spray containing a steroid and a antihistamine |
| BR9707369A (pt) * | 1996-02-08 | 1999-07-20 | Merck & Co Inc | Formulação farmacéutica e processo para tratamento de asma de alergia e de inflamação em um paciente |
| JPH11511758A (ja) * | 1996-06-04 | 1999-10-12 | ザ、プロクター、エンド、ギャンブル、カンパニー | 鼻腔用ステロイドと抗ヒスタミン剤を含む鼻腔内噴霧薬 |
| US5900421A (en) * | 1997-02-11 | 1999-05-04 | Sepracor Inc. | Methods and compositions for treating allergic asthma and dermatitis using descarboethoxyloratadine |
| CA2281789A1 (en) * | 1997-04-30 | 1998-11-05 | Warner-Lambert Company | Topical nasal antiinflammatory compositions |
-
1998
- 1998-12-21 DK DK98963828T patent/DK1041990T3/da active
- 1998-12-21 CA CA002315721A patent/CA2315721C/en not_active Expired - Fee Related
- 1998-12-21 PT PT98963828T patent/PT1041990E/pt unknown
- 1998-12-21 HU HU0101369A patent/HUP0101369A3/hu unknown
- 1998-12-21 JP JP2000525116A patent/JP2001526232A/ja active Pending
- 1998-12-21 PL PL341343A patent/PL193131B1/pl not_active IP Right Cessation
- 1998-12-21 DE DE69835103T patent/DE69835103T2/de not_active Expired - Lifetime
- 1998-12-21 AU AU19071/99A patent/AU758771B2/en not_active Ceased
- 1998-12-21 NZ NZ520907A patent/NZ520907A/en not_active IP Right Cessation
- 1998-12-21 CN CN98812638A patent/CN1283115A/zh active Pending
- 1998-12-21 AR ARP980106566A patent/AR017224A1/es not_active Application Discontinuation
- 1998-12-21 ID IDW20001217A patent/ID26390A/id unknown
- 1998-12-21 SK SK897-2000A patent/SK286103B6/sk not_active IP Right Cessation
- 1998-12-21 CZ CZ20002198A patent/CZ301349B6/cs not_active IP Right Cessation
- 1998-12-21 WO PCT/US1998/026223 patent/WO1999032125A1/en not_active Application Discontinuation
- 1998-12-21 MY MYPI98005791A patent/MY121744A/en unknown
- 1998-12-21 AT AT98963828T patent/ATE331522T1/de active
- 1998-12-21 IL IL13646198A patent/IL136461A0/xx not_active IP Right Cessation
- 1998-12-21 KR KR1020007006986A patent/KR100737710B1/ko not_active IP Right Cessation
- 1998-12-21 ES ES98963828T patent/ES2263229T3/es not_active Expired - Lifetime
- 1998-12-21 EP EP98963828A patent/EP1041990B1/en not_active Expired - Lifetime
- 1998-12-21 BR BR9814417-0A patent/BR9814417A/pt not_active Application Discontinuation
- 1998-12-22 PE PE1998001265A patent/PE20000126A1/es not_active Application Discontinuation
- 1998-12-22 CO CO98075939A patent/CO4980868A1/es unknown
-
1999
- 1999-04-20 SA SA99200013A patent/SA99200013B1/ar unknown
-
2000
- 2000-06-22 NO NO20003288A patent/NO20003288L/no not_active Application Discontinuation
- 2000-10-13 HK HK00106523A patent/HK1027502A1/xx not_active IP Right Cessation
-
2010
- 2010-12-27 JP JP2010291255A patent/JP2011068679A/ja not_active Withdrawn
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| Date | Code | Title | Description |
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| TC4A | Change of owner's name |
Owner name: MERCK SHARP & DOHME CORP., RAHWAY, NJ, US Effective date: 20121108 |
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| MM4A | Patent lapsed due to non-payment of maintenance fees |
Effective date: 20131221 |