HUP0101369A2 - Legalább egy leukotrién antagonistát és legalább egy antihisztamint tartalmazó készítmény légzőszervi és bőrbetegségek kezelésére - Google Patents
Legalább egy leukotrién antagonistát és legalább egy antihisztamint tartalmazó készítmény légzőszervi és bőrbetegségek kezeléséreInfo
- Publication number
- HUP0101369A2 HUP0101369A2 HU0101369A HUP0101369A HUP0101369A2 HU P0101369 A2 HUP0101369 A2 HU P0101369A2 HU 0101369 A HU0101369 A HU 0101369A HU P0101369 A HUP0101369 A HU P0101369A HU P0101369 A2 HUP0101369 A2 HU P0101369A2
- Authority
- HU
- Hungary
- Prior art keywords
- phenyl
- itching
- leukotriene antagonist
- ethenyl
- inflammation
- Prior art date
Links
- 239000003199 leukotriene receptor blocking agent Substances 0.000 title abstract 3
- GUGOEEXESWIERI-UHFFFAOYSA-N Terfenadine Chemical compound C1=CC(C(C)(C)C)=CC=C1C(O)CCCN1CCC(C(O)(C=2C=CC=CC=2)C=2C=CC=CC=2)CC1 GUGOEEXESWIERI-UHFFFAOYSA-N 0.000 title 1
- 230000001387 anti-histamine Effects 0.000 title 1
- 239000000739 antihistaminic agent Substances 0.000 title 1
- 230000000241 respiratory effect Effects 0.000 title 1
- 208000023504 respiratory system disease Diseases 0.000 title 1
- 208000017520 skin disease Diseases 0.000 title 1
- 208000003251 Pruritus Diseases 0.000 abstract 3
- 208000006673 asthma Diseases 0.000 abstract 3
- 230000007803 itching Effects 0.000 abstract 3
- 206010061218 Inflammation Diseases 0.000 abstract 2
- 208000002193 Pain Diseases 0.000 abstract 2
- QTBSBXVTEAMEQO-UHFFFAOYSA-N acetic acid Substances CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 2
- 201000009961 allergic asthma Diseases 0.000 abstract 2
- 230000004054 inflammatory process Effects 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- SFOVDSLXFUGAIV-UHFFFAOYSA-N 1-[(4-fluorophenyl)methyl]-n-piperidin-4-ylbenzimidazol-2-amine Chemical compound C1=CC(F)=CC=C1CN1C2=CC=CC=C2N=C1NC1CCNCC1 SFOVDSLXFUGAIV-UHFFFAOYSA-N 0.000 abstract 1
- BAWMMJAUVBLLEE-UHFFFAOYSA-N 2-[2-[4-[bis(4-fluorophenyl)methyl]piperazin-1-yl]ethoxy]acetic acid Chemical compound C1CN(CCOCC(=O)O)CCN1C(C=1C=CC(F)=CC=1)C1=CC=C(F)C=C1 BAWMMJAUVBLLEE-UHFFFAOYSA-N 0.000 abstract 1
- ZKLPARSLTMPFCP-UHFFFAOYSA-N Cetirizine Chemical compound C1CN(CCOCC(=O)O)CCN1C(C=1C=CC(Cl)=CC=1)C1=CC=CC=C1 ZKLPARSLTMPFCP-UHFFFAOYSA-N 0.000 abstract 1
- 206010011224 Cough Diseases 0.000 abstract 1
- 206010013975 Dyspnoeas Diseases 0.000 abstract 1
- 208000010201 Exanthema Diseases 0.000 abstract 1
- 206010019233 Headaches Diseases 0.000 abstract 1
- 206010020751 Hypersensitivity Diseases 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- UCHDWCPVSPXUMX-TZIWLTJVSA-N Montelukast Chemical compound CC(C)(O)C1=CC=CC=C1CC[C@H](C=1C=C(\C=C\C=2N=C3C=C(Cl)C=CC3=CC=2)C=CC=1)SCC1(CC(O)=O)CC1 UCHDWCPVSPXUMX-TZIWLTJVSA-N 0.000 abstract 1
- 208000005141 Otitis Diseases 0.000 abstract 1
- 206010039085 Rhinitis allergic Diseases 0.000 abstract 1
- 208000036071 Rhinorrhea Diseases 0.000 abstract 1
- 206010039101 Rhinorrhoea Diseases 0.000 abstract 1
- 125000000066 S-methyl group Chemical group [H]C([H])([H])S* 0.000 abstract 1
- 208000026935 allergic disease Diseases 0.000 abstract 1
- 201000010105 allergic rhinitis Diseases 0.000 abstract 1
- 230000007815 allergy Effects 0.000 abstract 1
- GXDALQBWZGODGZ-UHFFFAOYSA-N astemizole Chemical compound C1=CC(OC)=CC=C1CCN1CCC(NC=2N(C3=CC=CC=C3N=2)CC=2C=CC(F)=CC=2)CC1 GXDALQBWZGODGZ-UHFFFAOYSA-N 0.000 abstract 1
- 229960001803 cetirizine Drugs 0.000 abstract 1
- 208000019258 ear infection Diseases 0.000 abstract 1
- 210000005069 ears Anatomy 0.000 abstract 1
- 229960001971 ebastine Drugs 0.000 abstract 1
- MJJALKDDGIKVBE-UHFFFAOYSA-N ebastine Chemical compound C1=CC(C(C)(C)C)=CC=C1C(=O)CCCN1CCC(OC(C=2C=CC=CC=2)C=2C=CC=CC=2)CC1 MJJALKDDGIKVBE-UHFFFAOYSA-N 0.000 abstract 1
- 229950003420 efletirizine Drugs 0.000 abstract 1
- 229960003449 epinastine Drugs 0.000 abstract 1
- WHWZLSFABNNENI-UHFFFAOYSA-N epinastine Chemical compound C1C2=CC=CC=C2C2CN=C(N)N2C2=CC=CC=C21 WHWZLSFABNNENI-UHFFFAOYSA-N 0.000 abstract 1
- 208000001780 epistaxis Diseases 0.000 abstract 1
- 201000005884 exanthem Diseases 0.000 abstract 1
- 229960003592 fexofenadine Drugs 0.000 abstract 1
- RWTNPBWLLIMQHL-UHFFFAOYSA-N fexofenadine Chemical compound C1=CC(C(C)(C(O)=O)C)=CC=C1C(O)CCCN1CCC(C(O)(C=2C=CC=CC=2)C=2C=CC=CC=2)CC1 RWTNPBWLLIMQHL-UHFFFAOYSA-N 0.000 abstract 1
- 231100000869 headache Toxicity 0.000 abstract 1
- 229960003088 loratadine Drugs 0.000 abstract 1
- JCCNYMKQOSZNPW-UHFFFAOYSA-N loratadine Chemical compound C1CN(C(=O)OCC)CCC1=C1C2=NC=CC=C2CCC2=CC(Cl)=CC=C21 JCCNYMKQOSZNPW-UHFFFAOYSA-N 0.000 abstract 1
- 229960005127 montelukast Drugs 0.000 abstract 1
- 210000004877 mucosa Anatomy 0.000 abstract 1
- 201000009240 nasopharyngitis Diseases 0.000 abstract 1
- 230000036407 pain Effects 0.000 abstract 1
- 210000003254 palate Anatomy 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 229940127557 pharmaceutical product Drugs 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 229960004583 pranlukast Drugs 0.000 abstract 1
- UAJUXJSXCLUTNU-UHFFFAOYSA-N pranlukast Chemical compound C=1C=C(OCCCCC=2C=CC=CC=2)C=CC=1C(=O)NC(C=1)=CC=C(C(C=2)=O)C=1OC=2C=1N=NNN=1 UAJUXJSXCLUTNU-UHFFFAOYSA-N 0.000 abstract 1
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1
- 206010037844 rash Diseases 0.000 abstract 1
- 229910052594 sapphire Inorganic materials 0.000 abstract 1
- 239000010980 sapphire Substances 0.000 abstract 1
- 230000001932 seasonal effect Effects 0.000 abstract 1
- 201000009890 sinusitis Diseases 0.000 abstract 1
- 231100000046 skin rash Toxicity 0.000 abstract 1
- 206010041232 sneezing Diseases 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/10—Expectorants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/12—Mucolytics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Otolaryngology (AREA)
- Biomedical Technology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Abstract
A találmány tárgya gyógyszerkészítmény, amely emlősöknél tüsszentés,viszkető, folyó orr, orrvérbőség, szemvörösség, könnyezés, fül vagyszájpadlás viszketése, légzési nehézség, hörgőnyálkahártya-gyulladás,az egy másodperc alatti kényszerkilégzési térfogat csökkenése (FEV1),köhögés, bőrkiütés, bőrviszketés, fejfájások, szezonális allergiásasztmával együttjáró fájások és fájdalmak, egész éven át tartóallergiás rhinitis, közönséges meghűlés, fülgyulladás, orrmelléküreg-gyulladás, allergia, asztma, allergiás asztma és/vagy gyulladáskezelésére alkalmazható és tartalmazza: i) legalább egy leukotriénantagonista hatékony mennyiségét a: a) montelukast; b) 1-{(R)-1-{3-[2-(6,7-difluor-2-kinolil)-etenil]-fenil}-3-{[2-(1-hidroxi-1-metil-etil)-fenil]-tion-metil}-ciklopropil-<- ecetsav; c) 1-{[1(R)-3-{3-[2-(2,3-diklór-tieno[3,2-b]piridin-5-il)-(E)-etenil]-fenil}-3-[2-(1-hidroxi-1-metil-etil)-fenil]-propil] tio-metil}-ciklopropil-ecetsav; d)pranlukast; e) zafirlukast; vagy f)[2-{[2-(4-terc-butil-2-tiazolil)-5-benzofuranil]-oxi-metil}-fenil]-ecetsav; vagy gyógyszerészetilegelfogadható sóik közül; összekeverve ii) legalább egy leukotriénantagonista hatékony mennyiségével, a dez(etoxi-karbonil)-loratidin,cetirizin, fexofenadin, ebastin, astemizol, norastemizol, epinastin,efletirizin vagy gyógyszerészetileg elfogadható sóik közül. Ó
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US6863897P | 1997-12-23 | 1997-12-23 | |
US7863898P | 1998-03-19 | 1998-03-19 | |
PCT/US1998/026223 WO1999032125A1 (en) | 1997-12-23 | 1998-12-21 | Composition for treating respiratory and skin diseases, comprising at least one leukotriene antagonist and at least one antihistamine |
Publications (2)
Publication Number | Publication Date |
---|---|
HUP0101369A2 true HUP0101369A2 (hu) | 2002-03-28 |
HUP0101369A3 HUP0101369A3 (en) | 2002-11-28 |
Family
ID=26749192
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0101369A HUP0101369A3 (en) | 1997-12-23 | 1998-12-21 | Composition for treating respiratory and skin diseases, comprising at least one leukotriene antagonist and at least one antihistamine |
Country Status (27)
Country | Link |
---|---|
EP (1) | EP1041990B1 (hu) |
JP (2) | JP2001526232A (hu) |
KR (1) | KR100737710B1 (hu) |
CN (1) | CN1283115A (hu) |
AR (1) | AR017224A1 (hu) |
AT (1) | ATE331522T1 (hu) |
AU (1) | AU758771B2 (hu) |
BR (1) | BR9814417A (hu) |
CA (1) | CA2315721C (hu) |
CO (1) | CO4980868A1 (hu) |
CZ (1) | CZ301349B6 (hu) |
DE (1) | DE69835103T2 (hu) |
DK (1) | DK1041990T3 (hu) |
ES (1) | ES2263229T3 (hu) |
HK (1) | HK1027502A1 (hu) |
HU (1) | HUP0101369A3 (hu) |
ID (1) | ID26390A (hu) |
IL (1) | IL136461A0 (hu) |
MY (1) | MY121744A (hu) |
NO (1) | NO20003288L (hu) |
NZ (1) | NZ520907A (hu) |
PE (1) | PE20000126A1 (hu) |
PL (1) | PL193131B1 (hu) |
PT (1) | PT1041990E (hu) |
SA (1) | SA99200013B1 (hu) |
SK (1) | SK286103B6 (hu) |
WO (1) | WO1999032125A1 (hu) |
Families Citing this family (47)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6303632B1 (en) | 1992-09-03 | 2001-10-16 | Sepracor Inc. | Compositions for treating allergic and other disorders using norastemizole in combination with other active ingredients |
ES2210957T3 (es) | 1992-09-03 | 2004-07-01 | Sepracor Inc. | Composiciones farmaceuticas que contienen norastemizol. |
US7214683B1 (en) | 1994-12-30 | 2007-05-08 | Sepracor Inc. | Compositions of descarboethoxyloratadine |
US7211582B1 (en) | 1994-12-30 | 2007-05-01 | Sepracor Inc. | Methods for treating urticaria using descarboethoxyloratadine |
US6248308B1 (en) | 1998-04-14 | 2001-06-19 | Sepracor Inc. | Methods of using norastemizole in combination with leukotriene inhibitors to treat or prevent asthma |
US6384038B1 (en) | 1998-04-14 | 2002-05-07 | Sepracor Inc. | Methods and compositions using cetirizine in combination with leukotriene inhibitors or decongestants |
US6194431B1 (en) | 1998-04-14 | 2001-02-27 | Paul D. Rubin | Methods and compositions using terfenadine metabolites in combination with leukotriene inhibitors |
IT1303671B1 (it) | 1998-07-28 | 2001-02-23 | Nicox Sa | Sali dell'acido nitrico con farmaci attivi nel trattamento dipatologie del sistema respiratorio |
EP1000623A1 (en) * | 1998-09-29 | 2000-05-17 | BOEHRINGER INGELHEIM INTERNATIONAL GmbH | Use of epinastine as antitussivum |
US20020198246A1 (en) | 1998-09-30 | 2002-12-26 | Ono Pharmaceutical Co., Ltd. | Agent for preventing and/or treating sinusitis |
JP3627801B2 (ja) * | 1998-09-30 | 2005-03-09 | 小野薬品工業株式会社 | 副鼻腔炎の予防および/または治療剤 |
US7405223B2 (en) | 2000-02-03 | 2008-07-29 | Schering Corporation | Treating allergic and inflammatory conditions |
CA2398261A1 (en) * | 2000-02-03 | 2001-08-09 | Schering Corporation | Treating allergic and inflammatory conditions |
DE10007203A1 (de) | 2000-02-17 | 2001-08-23 | Asta Medica Ag | Neue Kombination nichtsedierender Antihistaminika mit Substanzen, die die Leukotrienwirkung beeinflussen, zur Behandlung der Rhinitis/Konjunktivitis |
JP2002087963A (ja) * | 2000-09-08 | 2002-03-27 | Nippon Boehringer Ingelheim Co Ltd | 直接打錠により製造されたエピナスチン含有錠剤 |
PE20020324A1 (es) * | 2000-10-06 | 2002-06-18 | Boehringer Ingelheim Int | Nuevas composiciones farmaceuticas que contienen epinastina y pseudoefedrina |
US20020094345A1 (en) | 2000-10-06 | 2002-07-18 | Sara Abelaira | Pharmaceutical compositions containing epinastine and pseudoephedrine |
JP4074427B2 (ja) * | 2000-12-18 | 2008-04-09 | 株式会社栃木臨床病理研究所 | 子宮内膜症の予防又は治療薬 |
US20020198228A1 (en) * | 2001-04-03 | 2002-12-26 | Kaura Sita R. | Composition and method for the treatment of respiratory desease |
WO2003000264A1 (en) * | 2001-06-20 | 2003-01-03 | Schering Corporation | Antihistamines for the treatment of nasal congestion and nasal obstruction |
GB0115181D0 (en) * | 2001-06-20 | 2001-08-15 | Glaxo Group Ltd | Novel use |
US7014867B2 (en) | 2001-06-28 | 2006-03-21 | Ucb Farchim Sa | Tablet comprising cetirizine and pseudoephedrine |
MY148466A (en) | 2001-10-26 | 2013-04-30 | Merck Frosst Canada Ltd | Granule formulation |
AU2003264859A1 (en) * | 2001-12-21 | 2003-12-19 | Sampad Bhattacharya | Intranasal pharmaceutical compositions comprising an antihistamine and a leukotriene inhibitor |
WO2003101437A2 (en) * | 2002-05-29 | 2003-12-11 | Aventis Pharmaceuticals Holdings Inc. | Method of treating asthma using fexofenadine |
DE60319227T2 (de) * | 2002-07-02 | 2009-05-07 | Ucb Farchim S.A. | Diarylmethylpiperazines als prophylaktische oder therapeutische mittel gegen virale myocarditis |
AU2003288041A1 (en) * | 2002-12-06 | 2004-06-30 | Ucb Farchim, S.A. | Tablet comprising efletirizine and pseudoephedrine |
WO2004087095A2 (es) * | 2003-03-31 | 2004-10-14 | Osmotica Costa Rica, Sociedad Anonima | Dispositivo osmótico que contiene zafirlukast y un antagonista h1 |
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