SK284903B6 - Spôsob výroby 1-(6-metylpyridín-3-yl)-2-[(4- (metylsulfonyl)fenyl]etanónu a medziprodukty - Google Patents
Spôsob výroby 1-(6-metylpyridín-3-yl)-2-[(4- (metylsulfonyl)fenyl]etanónu a medziprodukty Download PDFInfo
- Publication number
- SK284903B6 SK284903B6 SK972-2001A SK9722001A SK284903B6 SK 284903 B6 SK284903 B6 SK 284903B6 SK 9722001 A SK9722001 A SK 9722001A SK 284903 B6 SK284903 B6 SK 284903B6
- Authority
- SK
- Slovakia
- Prior art keywords
- methyl
- methylpyridin
- formula
- carbaldehyde
- acetonitrile
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/57—Nitriles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/46—Oxygen atoms
- C07D213/50—Ketonic radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP99100590 | 1999-01-14 | ||
| US14599699P | 1999-07-29 | 1999-07-29 | |
| PCT/EP2000/000240 WO2000042014A2 (de) | 1999-01-14 | 2000-01-13 | 1-(6-methylpyridin-3-yl)-2-((4-(methylsulfonyl)phenyl)ethanon und verfahren zu seiner herstellung |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SK9722001A3 SK9722001A3 (en) | 2001-12-03 |
| SK284903B6 true SK284903B6 (sk) | 2006-02-02 |
Family
ID=34089809
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK972-2001A SK284903B6 (sk) | 1999-01-14 | 2000-01-13 | Spôsob výroby 1-(6-metylpyridín-3-yl)-2-[(4- (metylsulfonyl)fenyl]etanónu a medziprodukty |
Country Status (15)
| Country | Link |
|---|---|
| EP (2) | EP1394149B1 (hu) |
| JP (1) | JP4765167B2 (hu) |
| CN (2) | CN1170820C (hu) |
| AT (2) | ATE253559T1 (hu) |
| AU (1) | AU2290800A (hu) |
| CA (2) | CA2359958C (hu) |
| CZ (1) | CZ302270B6 (hu) |
| DE (2) | DE50004327D1 (hu) |
| DK (2) | DK1159270T3 (hu) |
| ES (2) | ES2209807T3 (hu) |
| HU (1) | HUP0105124A3 (hu) |
| IL (1) | IL143981A0 (hu) |
| PT (2) | PT1394149E (hu) |
| SK (1) | SK284903B6 (hu) |
| WO (1) | WO2000042014A2 (hu) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104725300A (zh) * | 2015-02-28 | 2015-06-24 | 宁波九胜创新医药科技有限公司 | 一种1-(6-甲基吡啶-3-基)-2-(4-甲磺酰基苯基)乙酮的制备方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3313683A (en) * | 1963-04-22 | 1967-04-11 | Lilly Co Eli | Nematocidal and fungicidal methods |
| FR2074674A1 (en) * | 1970-01-16 | 1971-10-08 | Simafex | Sulphonamide/aldehyde-bisulphite complexes - antibacterials with very high solubility in water |
| US4155909A (en) * | 1977-06-13 | 1979-05-22 | Philip Morris Incorporated | 2-Alkyl nicotinoids and processes for their production |
| US5596008A (en) * | 1995-02-10 | 1997-01-21 | G. D. Searle & Co. | 3,4-Diaryl substituted pyridines for the treatment of inflammation |
| HU227732B1 (en) * | 1996-07-18 | 2012-01-30 | Merck Frosst Canada Ltd | Substituted pyridine derivatives as selective cyclooxigenase-2 inhibitors and use thereof |
| TW492959B (en) * | 1997-04-18 | 2002-07-01 | Merck & Co Inc | Process for making 2-aryl-3-aryl-5-halo pyridines useful as cox-2 inhibitors |
| AR015938A1 (es) * | 1997-09-25 | 2001-05-30 | Merck Sharp & Dohme | Procedimiento para preparar diaril piridinas utiles como inhibidores cox-2 y compuesto intermediario |
| AU759469B2 (en) * | 1998-04-24 | 2003-04-17 | Merck Sharp & Dohme Corp. | Process for synthesizing cox-2 inhibitors |
-
2000
- 2000-01-13 AT AT00901555T patent/ATE253559T1/de active
- 2000-01-13 CA CA002359958A patent/CA2359958C/en not_active Expired - Fee Related
- 2000-01-13 ES ES00901555T patent/ES2209807T3/es not_active Expired - Lifetime
- 2000-01-13 HU HU0105124A patent/HUP0105124A3/hu unknown
- 2000-01-13 CN CNB008027218A patent/CN1170820C/zh not_active Expired - Fee Related
- 2000-01-13 JP JP2000593582A patent/JP4765167B2/ja not_active Expired - Fee Related
- 2000-01-13 AT AT03024787T patent/ATE287396T1/de active
- 2000-01-13 PT PT03024787T patent/PT1394149E/pt unknown
- 2000-01-13 CA CA002485739A patent/CA2485739C/en not_active Expired - Fee Related
- 2000-01-13 DK DK00901555T patent/DK1159270T3/da active
- 2000-01-13 WO PCT/EP2000/000240 patent/WO2000042014A2/de active Application Filing
- 2000-01-13 DK DK03024787T patent/DK1394149T3/da active
- 2000-01-13 SK SK972-2001A patent/SK284903B6/sk not_active IP Right Cessation
- 2000-01-13 EP EP03024787A patent/EP1394149B1/de not_active Expired - Lifetime
- 2000-01-13 CN CNB200410069946XA patent/CN1281589C/zh not_active Expired - Fee Related
- 2000-01-13 CZ CZ20012457A patent/CZ302270B6/cs not_active IP Right Cessation
- 2000-01-13 AU AU22908/00A patent/AU2290800A/en not_active Abandoned
- 2000-01-13 DE DE50004327T patent/DE50004327D1/de not_active Expired - Lifetime
- 2000-01-13 DE DE50009312T patent/DE50009312D1/de not_active Expired - Lifetime
- 2000-01-13 ES ES03024787T patent/ES2235138T3/es not_active Expired - Lifetime
- 2000-01-13 IL IL14398100A patent/IL143981A0/xx active IP Right Grant
- 2000-01-13 PT PT00901555T patent/PT1159270E/pt unknown
- 2000-01-13 EP EP00901555A patent/EP1159270B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| HUP0105124A3 (en) | 2002-05-28 |
| CN1359374A (zh) | 2002-07-17 |
| HUP0105124A2 (hu) | 2002-04-29 |
| CN1583723A (zh) | 2005-02-23 |
| DE50009312D1 (de) | 2005-02-24 |
| CN1170820C (zh) | 2004-10-13 |
| DK1394149T3 (da) | 2005-04-04 |
| DE50004327D1 (de) | 2003-12-11 |
| PT1394149E (pt) | 2005-05-31 |
| DK1159270T3 (da) | 2004-02-23 |
| CZ302270B6 (cs) | 2011-01-19 |
| CN1281589C (zh) | 2006-10-25 |
| CA2359958C (en) | 2006-04-04 |
| AU2290800A (en) | 2000-08-01 |
| ES2209807T3 (es) | 2004-07-01 |
| CA2485739C (en) | 2009-09-22 |
| SK9722001A3 (en) | 2001-12-03 |
| CZ20012457A3 (cs) | 2002-01-16 |
| JP4765167B2 (ja) | 2011-09-07 |
| WO2000042014A2 (de) | 2000-07-20 |
| EP1394149B1 (de) | 2005-01-19 |
| CA2485739A1 (en) | 2000-07-20 |
| EP1394149A1 (de) | 2004-03-03 |
| ATE287396T1 (de) | 2005-02-15 |
| EP1159270A2 (de) | 2001-12-05 |
| IL143981A0 (en) | 2002-04-21 |
| EP1159270B1 (de) | 2003-11-05 |
| ATE253559T1 (de) | 2003-11-15 |
| JP2003518002A (ja) | 2003-06-03 |
| PT1159270E (pt) | 2004-03-31 |
| WO2000042014A3 (de) | 2000-12-07 |
| CA2359958A1 (en) | 2000-07-20 |
| ES2235138T3 (es) | 2005-07-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Patent lapsed due to non-payment of maintenance fees |
Effective date: 20120113 |