FR2074674A1 - Sulphonamide/aldehyde-bisulphite complexes - antibacterials with very high solubility in water - Google Patents

Sulphonamide/aldehyde-bisulphite complexes - antibacterials with very high solubility in water

Info

Publication number
FR2074674A1
FR2074674A1 FR7001517A FR7001517A FR2074674A1 FR 2074674 A1 FR2074674 A1 FR 2074674A1 FR 7001517 A FR7001517 A FR 7001517A FR 7001517 A FR7001517 A FR 7001517A FR 2074674 A1 FR2074674 A1 FR 2074674A1
Authority
FR
France
Prior art keywords
aldehyde
bisulphite
alkyl
sulphonamide
complexes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7001517A
Other languages
French (fr)
Other versions
FR2074674B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Simafex SA
Original Assignee
Simafex SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Simafex SA filed Critical Simafex SA
Priority to FR7001517A priority Critical patent/FR2074674A1/en
Priority to ES387248A priority patent/ES387248A1/en
Publication of FR2074674A1 publication Critical patent/FR2074674A1/en
Application granted granted Critical
Publication of FR2074674B1 publication Critical patent/FR2074674B1/fr
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides

Abstract

Antibacterial sulphonamide/aldehyde-bisulphite complexes are of formula: where n is an integer preferably 1 or 2; R1 has a valency equal to that of n and is alkyl, furfuryl, pyridinyl aryl opt. substd. by >=1 halogen, alkyl, alkoxy, NH2, p-OH, m-OH, or a polyvalent group derived from one of these substituents; R2 = H, pyrimidinyl disubstd. by alkyl, alkoxy, halogen; pyridazinyl, thiofurazanyl, thiazolyl, thiodiazolyl opt. substd. by >=1 alkyl, alkoxy or halogen Prepared by treating a sulphanilamide with 2/n moles of the aldehyde bisulphite compound of formula: at 50-105 degrees C in aqueous solution. Used for treating lymphangitis and paronychia in cattle.
FR7001517A 1970-01-16 1970-01-16 Sulphonamide/aldehyde-bisulphite complexes - antibacterials with very high solubility in water Granted FR2074674A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
FR7001517A FR2074674A1 (en) 1970-01-16 1970-01-16 Sulphonamide/aldehyde-bisulphite complexes - antibacterials with very high solubility in water
ES387248A ES387248A1 (en) 1970-01-16 1971-01-14 Procedure for preparing a compound with therapeutic activity. (Machine-translation by Google Translate, not legally binding)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7001517A FR2074674A1 (en) 1970-01-16 1970-01-16 Sulphonamide/aldehyde-bisulphite complexes - antibacterials with very high solubility in water

Publications (2)

Publication Number Publication Date
FR2074674A1 true FR2074674A1 (en) 1971-10-08
FR2074674B1 FR2074674B1 (en) 1973-01-12

Family

ID=9049133

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7001517A Granted FR2074674A1 (en) 1970-01-16 1970-01-16 Sulphonamide/aldehyde-bisulphite complexes - antibacterials with very high solubility in water

Country Status (2)

Country Link
ES (1) ES387248A1 (en)
FR (1) FR2074674A1 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000042014A2 (en) * 1999-01-14 2000-07-20 Lonza Ag 1-(6- methylpyridine- 3-yl)-2-[4- (methylsulfonyl) phenyl] ethanone and method for its preparation
US7141673B1 (en) 1999-01-14 2006-11-28 Lonza Ag 1-(6-methylpyridine-3-yl)-2-[4-(methylsulphonyl) phenyl] ethanone and method for its preparation

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR892554A (en) * 1942-05-02 1944-04-12 Benzon As Alfred Process for the preparation of sulfanilamide compounds
US2696454A (en) * 1949-12-12 1954-12-07 Schenley Ind Inc Parenterally administrable aqueous solutions of sulfa-compounds and process of preparation thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR892554A (en) * 1942-05-02 1944-04-12 Benzon As Alfred Process for the preparation of sulfanilamide compounds
US2696454A (en) * 1949-12-12 1954-12-07 Schenley Ind Inc Parenterally administrable aqueous solutions of sulfa-compounds and process of preparation thereof

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000042014A2 (en) * 1999-01-14 2000-07-20 Lonza Ag 1-(6- methylpyridine- 3-yl)-2-[4- (methylsulfonyl) phenyl] ethanone and method for its preparation
WO2000042014A3 (en) * 1999-01-14 2000-12-07 Lonza Ag 1-(6- methylpyridine- 3-yl)-2-[4- (methylsulfonyl) phenyl] ethanone and method for its preparation
JP2003518002A (en) * 1999-01-14 2003-06-03 ロンザ ア−ゲ− 1- (6-methylpyridin-3-yl) -2- [4- (methylsulfonyl) phenyl] ethanone and method for producing the same
US7141673B1 (en) 1999-01-14 2006-11-28 Lonza Ag 1-(6-methylpyridine-3-yl)-2-[4-(methylsulphonyl) phenyl] ethanone and method for its preparation
US7355048B2 (en) 1999-01-14 2008-04-08 Lonza Ltd. Process for preparing 1-(6-methylpyridin-3-yl)-2-[4- (methylsulphonyl)phenyl]ethanone
JP4765167B2 (en) * 1999-01-14 2011-09-07 ロンザ アーゲー 1- (6-Methylpyridin-3-yl) -2- [4- (methylsulfonyl) phenyl] ethanone and process for producing the same

Also Published As

Publication number Publication date
FR2074674B1 (en) 1973-01-12
ES387248A1 (en) 1975-01-01

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