DK1394149T3 - Fremgangsmåde til fremstilling af 1-(6-methylpyridin-3-yl)-2-[4-(methylsulfonyl)phenyl]ethanon - Google Patents
Fremgangsmåde til fremstilling af 1-(6-methylpyridin-3-yl)-2-[4-(methylsulfonyl)phenyl]ethanonInfo
- Publication number
- DK1394149T3 DK1394149T3 DK03024787T DK03024787T DK1394149T3 DK 1394149 T3 DK1394149 T3 DK 1394149T3 DK 03024787 T DK03024787 T DK 03024787T DK 03024787 T DK03024787 T DK 03024787T DK 1394149 T3 DK1394149 T3 DK 1394149T3
- Authority
- DK
- Denmark
- Prior art keywords
- methylpyridin
- preparation
- ethanone
- methylsulfonyl
- phenyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/57—Nitriles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/46—Oxygen atoms
- C07D213/50—Ketonic radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP99100590 | 1999-01-14 | ||
| EP00901555A EP1159270B1 (de) | 1999-01-14 | 2000-01-13 | Verfahren zur herstellung von 1-(6-methylpyridin-3-yl)-2- 4-(methylsulfonyl phenyl)ethanon |
| EP03024787A EP1394149B1 (de) | 1999-01-14 | 2000-01-13 | Verfahren zur Herstellung von 1-(6-Methylpyridin-3-yl)-2-[4-(methylsulfonyl)-phenyl]ethanon |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1394149T3 true DK1394149T3 (da) | 2005-04-04 |
Family
ID=34089809
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK00901555T DK1159270T3 (da) | 1999-01-14 | 2000-01-13 | Fremgangsmåde til fremstilling af 1-(6-methylpyridin-3-yl)-2-[(4-(methylsulfonyl)phenyl]ethanon |
| DK03024787T DK1394149T3 (da) | 1999-01-14 | 2000-01-13 | Fremgangsmåde til fremstilling af 1-(6-methylpyridin-3-yl)-2-[4-(methylsulfonyl)phenyl]ethanon |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK00901555T DK1159270T3 (da) | 1999-01-14 | 2000-01-13 | Fremgangsmåde til fremstilling af 1-(6-methylpyridin-3-yl)-2-[(4-(methylsulfonyl)phenyl]ethanon |
Country Status (15)
| Country | Link |
|---|---|
| EP (2) | EP1394149B1 (da) |
| JP (1) | JP4765167B2 (da) |
| CN (2) | CN1281589C (da) |
| AT (2) | ATE253559T1 (da) |
| AU (1) | AU2290800A (da) |
| CA (2) | CA2485739C (da) |
| CZ (1) | CZ302270B6 (da) |
| DE (2) | DE50009312D1 (da) |
| DK (2) | DK1159270T3 (da) |
| ES (2) | ES2235138T3 (da) |
| HU (1) | HUP0105124A3 (da) |
| IL (1) | IL143981A0 (da) |
| PT (2) | PT1159270E (da) |
| SK (1) | SK284903B6 (da) |
| WO (1) | WO2000042014A2 (da) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104725300A (zh) * | 2015-02-28 | 2015-06-24 | 宁波九胜创新医药科技有限公司 | 一种1-(6-甲基吡啶-3-基)-2-(4-甲磺酰基苯基)乙酮的制备方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3313683A (en) * | 1963-04-22 | 1967-04-11 | Lilly Co Eli | Nematocidal and fungicidal methods |
| FR2074674A1 (en) * | 1970-01-16 | 1971-10-08 | Simafex | Sulphonamide/aldehyde-bisulphite complexes - antibacterials with very high solubility in water |
| US4155909A (en) * | 1977-06-13 | 1979-05-22 | Philip Morris Incorporated | 2-Alkyl nicotinoids and processes for their production |
| US5596008A (en) * | 1995-02-10 | 1997-01-21 | G. D. Searle & Co. | 3,4-Diaryl substituted pyridines for the treatment of inflammation |
| SI0912518T1 (en) * | 1996-07-18 | 2003-12-31 | Merck Frosst Canada & Co. | Substituted pyridines as selective cyclooxygenase-2 inhibitors |
| TW492959B (en) * | 1997-04-18 | 2002-07-01 | Merck & Co Inc | Process for making 2-aryl-3-aryl-5-halo pyridines useful as cox-2 inhibitors |
| AR015938A1 (es) * | 1997-09-25 | 2001-05-30 | Merck Sharp & Dohme | Procedimiento para preparar diaril piridinas utiles como inhibidores cox-2 y compuesto intermediario |
| AU759469B2 (en) * | 1998-04-24 | 2003-04-17 | Merck Sharp & Dohme Corp. | Process for synthesizing cox-2 inhibitors |
-
2000
- 2000-01-13 DK DK00901555T patent/DK1159270T3/da active
- 2000-01-13 AT AT00901555T patent/ATE253559T1/de active
- 2000-01-13 SK SK972-2001A patent/SK284903B6/sk not_active IP Right Cessation
- 2000-01-13 CN CNB200410069946XA patent/CN1281589C/zh not_active Expired - Fee Related
- 2000-01-13 AT AT03024787T patent/ATE287396T1/de active
- 2000-01-13 JP JP2000593582A patent/JP4765167B2/ja not_active Expired - Fee Related
- 2000-01-13 DE DE50009312T patent/DE50009312D1/de not_active Expired - Lifetime
- 2000-01-13 WO PCT/EP2000/000240 patent/WO2000042014A2/de active Application Filing
- 2000-01-13 CA CA002485739A patent/CA2485739C/en not_active Expired - Fee Related
- 2000-01-13 EP EP03024787A patent/EP1394149B1/de not_active Expired - Lifetime
- 2000-01-13 ES ES03024787T patent/ES2235138T3/es not_active Expired - Lifetime
- 2000-01-13 CA CA002359958A patent/CA2359958C/en not_active Expired - Fee Related
- 2000-01-13 PT PT00901555T patent/PT1159270E/pt unknown
- 2000-01-13 EP EP00901555A patent/EP1159270B1/de not_active Expired - Lifetime
- 2000-01-13 AU AU22908/00A patent/AU2290800A/en not_active Abandoned
- 2000-01-13 ES ES00901555T patent/ES2209807T3/es not_active Expired - Lifetime
- 2000-01-13 HU HU0105124A patent/HUP0105124A3/hu unknown
- 2000-01-13 CZ CZ20012457A patent/CZ302270B6/cs not_active IP Right Cessation
- 2000-01-13 DE DE50004327T patent/DE50004327D1/de not_active Expired - Lifetime
- 2000-01-13 CN CNB008027218A patent/CN1170820C/zh not_active Expired - Fee Related
- 2000-01-13 DK DK03024787T patent/DK1394149T3/da active
- 2000-01-13 IL IL14398100A patent/IL143981A0/xx active IP Right Grant
- 2000-01-13 PT PT03024787T patent/PT1394149E/pt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2290800A (en) | 2000-08-01 |
| PT1394149E (pt) | 2005-05-31 |
| EP1394149A1 (de) | 2004-03-03 |
| CN1170820C (zh) | 2004-10-13 |
| DK1159270T3 (da) | 2004-02-23 |
| CA2485739C (en) | 2009-09-22 |
| CZ20012457A3 (cs) | 2002-01-16 |
| CN1583723A (zh) | 2005-02-23 |
| SK9722001A3 (en) | 2001-12-03 |
| WO2000042014A3 (de) | 2000-12-07 |
| PT1159270E (pt) | 2004-03-31 |
| SK284903B6 (sk) | 2006-02-02 |
| CA2485739A1 (en) | 2000-07-20 |
| DE50009312D1 (de) | 2005-02-24 |
| ES2209807T3 (es) | 2004-07-01 |
| EP1159270B1 (de) | 2003-11-05 |
| JP2003518002A (ja) | 2003-06-03 |
| EP1394149B1 (de) | 2005-01-19 |
| JP4765167B2 (ja) | 2011-09-07 |
| IL143981A0 (en) | 2002-04-21 |
| DE50004327D1 (de) | 2003-12-11 |
| CN1281589C (zh) | 2006-10-25 |
| ATE287396T1 (de) | 2005-02-15 |
| CA2359958C (en) | 2006-04-04 |
| HUP0105124A2 (hu) | 2002-04-29 |
| HUP0105124A3 (en) | 2002-05-28 |
| CN1359374A (zh) | 2002-07-17 |
| CZ302270B6 (cs) | 2011-01-19 |
| CA2359958A1 (en) | 2000-07-20 |
| ES2235138T3 (es) | 2005-07-01 |
| WO2000042014A2 (de) | 2000-07-20 |
| EP1159270A2 (de) | 2001-12-05 |
| ATE253559T1 (de) | 2003-11-15 |
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