SK282703B6 - Benzoxazinónový derivát, jeho použitie a farmaceutický prostriedok na jeho báze - Google Patents
Benzoxazinónový derivát, jeho použitie a farmaceutický prostriedok na jeho báze Download PDFInfo
- Publication number
- SK282703B6 SK282703B6 SK1627-98A SK162798A SK282703B6 SK 282703 B6 SK282703 B6 SK 282703B6 SK 162798 A SK162798 A SK 162798A SK 282703 B6 SK282703 B6 SK 282703B6
- Authority
- SK
- Slovakia
- Prior art keywords
- benzo
- ylmethyl
- oxazin
- piperazin
- phenyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
- C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hospice & Palliative Care (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US1838396P | 1996-05-29 | 1996-05-29 | |
US4020897P | 1997-03-06 | 1997-03-06 | |
PCT/US1997/008524 WO1997045419A1 (en) | 1996-05-29 | 1997-05-20 | Benzoxazinone dopamine d4 receptor antagonists |
Publications (2)
Publication Number | Publication Date |
---|---|
SK162798A3 SK162798A3 (en) | 1999-06-11 |
SK282703B6 true SK282703B6 (sk) | 2002-11-06 |
Family
ID=26691052
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SK1627-98A SK282703B6 (sk) | 1996-05-29 | 1997-05-20 | Benzoxazinónový derivát, jeho použitie a farmaceutický prostriedok na jeho báze |
Country Status (37)
Country | Link |
---|---|
EP (1) | EP0906294B1 (xx) |
JP (1) | JP2000511534A (xx) |
KR (1) | KR20000016151A (xx) |
CN (1) | CN1074764C (xx) |
AR (1) | AR008372A1 (xx) |
AT (1) | ATE231846T1 (xx) |
AU (1) | AU731104B2 (xx) |
BG (1) | BG64049B1 (xx) |
BR (1) | BR9709630A (xx) |
CA (1) | CA2253406A1 (xx) |
CO (1) | CO4940505A1 (xx) |
CZ (1) | CZ384698A3 (xx) |
DE (1) | DE69718786T2 (xx) |
DK (1) | DK0906294T3 (xx) |
EA (1) | EA001486B1 (xx) |
EE (1) | EE03686B1 (xx) |
ES (1) | ES2191180T3 (xx) |
GE (1) | GEP20012389B (xx) |
HK (1) | HK1019737A1 (xx) |
HN (1) | HN1997000075A (xx) |
HR (1) | HRP970301B1 (xx) |
HU (1) | HUP9903758A3 (xx) |
ID (1) | ID17266A (xx) |
IL (1) | IL126895A (xx) |
NO (1) | NO312296B1 (xx) |
NZ (1) | NZ332737A (xx) |
PA (1) | PA8431101A1 (xx) |
PE (1) | PE69398A1 (xx) |
PL (1) | PL330195A1 (xx) |
PT (1) | PT906294E (xx) |
RO (1) | RO120845B1 (xx) |
SI (1) | SI0906294T1 (xx) |
SK (1) | SK282703B6 (xx) |
SV (1) | SV1997000047A (xx) |
TW (1) | TW542833B (xx) |
UY (1) | UY24569A1 (xx) |
WO (1) | WO1997045419A1 (xx) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6177422B1 (en) | 1996-05-29 | 2001-01-23 | Warner-Lambert Company | Benzoxazinone dopamine D4 receptor antagonists |
GB9801392D0 (en) * | 1998-01-22 | 1998-03-18 | Smithkline Beecham Plc | Novel compounds |
WO2000000489A2 (en) * | 1998-06-30 | 2000-01-06 | Neurogen Corporation | 6-(4-arylalkylpiperazin-1-yl)benzodioxane and 6-(4-arylalkylpiperazin-1-yl)chromane derivatives: dopamine receptor subtype specific ligands |
US6291463B1 (en) | 1998-06-30 | 2001-09-18 | Neurogen Corporation | 1-(Benzothiazol-2-yl)-4-(1-phenylmethyl) piperazines: dopamine receptor subtype specific ligands |
US6177566B1 (en) | 1998-06-30 | 2001-01-23 | Neurogen Corporation | 6-(4-arylalkylpiperazin-1-yl) benzodioxane and 6-(4-arylalkylpiperazin-1-yl) chromane derivatives: dopamine receptor subtype specific ligands |
EP1089990A1 (en) * | 1998-06-30 | 2001-04-11 | Neurogen Corporation | 1-(benzothiazol-2-yl)-4-(1-phenylmethyl)piperazines: dopamine receptor subtype specific ligands |
DE19844291A1 (de) | 1998-09-18 | 2000-03-23 | Schering Ag | Benzoxazin- und Benzothiazin-Derivate und deren Verwendung in Arzneimitteln |
GB9912411D0 (en) * | 1999-05-28 | 1999-07-28 | Pfizer Ltd | Compounds useful in therapy |
CZ20031163A3 (cs) | 2000-10-26 | 2004-04-14 | Smithkline Beecham P. L. C. | Deriváty benzoxazinonu, způsob jejich přípravy, jejich použití a farmaceutický prostředek, který je obsahuje |
GB0203804D0 (en) | 2002-02-18 | 2002-04-03 | Glaxo Group Ltd | Compounds |
GB0209244D0 (en) * | 2002-04-23 | 2002-06-05 | Glaxo Group Ltd | Compounds |
GB0227240D0 (en) * | 2002-11-21 | 2002-12-31 | Glaxo Group Ltd | Compounds |
ES2232292B1 (es) * | 2003-07-30 | 2006-11-01 | Laboratorios Del Dr. Esteve, S.A. | Compuestos sulfonamidicos derivados de benzoxazinona, su preparacion y uso como medicamentos. |
CN100455573C (zh) * | 2005-11-11 | 2009-01-28 | 华东理工大学 | 一种制备1,4-苯并噁唑嗪-3-酮化合物的微波合成方法 |
KR200482995Y1 (ko) | 2015-08-19 | 2017-03-23 | 이현진 | 물 공급부를 구비하는 얼음 트레이 |
CA3215823A1 (en) * | 2021-04-23 | 2022-10-27 | Peng Gao | Heterocyclic derivative inhibitor and preparation method therefor and application thereof |
WO2023207283A1 (en) * | 2022-04-28 | 2023-11-02 | Ningbo Newbay Technology Development Co., Ltd | Compounds as parp1 inhibitiors |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4613598A (en) * | 1984-03-13 | 1986-09-23 | Mitsubishi Chemical Industries Limited | Piperazine derivatives and their acid addition salts |
EP0233728A1 (en) * | 1986-02-11 | 1987-08-26 | Takeda Chemical Industries, Ltd. | 1,4-Benzoxazine derivatives their production and use |
JPH07509705A (ja) * | 1992-08-06 | 1995-10-26 | スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー | ドーパミンd3レセプター拮抗薬用5−(2−オキシフェニル)−ピロール誘導体 |
-
1997
- 1997-05-20 IL IL12689597A patent/IL126895A/en not_active IP Right Cessation
- 1997-05-20 PT PT97925651T patent/PT906294E/pt unknown
- 1997-05-20 SK SK1627-98A patent/SK282703B6/sk unknown
- 1997-05-20 ES ES97925651T patent/ES2191180T3/es not_active Expired - Lifetime
- 1997-05-20 DK DK97925651T patent/DK0906294T3/da active
- 1997-05-20 GE GEAP19974623A patent/GEP20012389B/en unknown
- 1997-05-20 JP JP09542647A patent/JP2000511534A/ja not_active Ceased
- 1997-05-20 HU HU9903758A patent/HUP9903758A3/hu unknown
- 1997-05-20 AT AT97925651T patent/ATE231846T1/de not_active IP Right Cessation
- 1997-05-20 RO RO98-01622A patent/RO120845B1/ro unknown
- 1997-05-20 AU AU30727/97A patent/AU731104B2/en not_active Ceased
- 1997-05-20 BR BR9709630A patent/BR9709630A/pt not_active Application Discontinuation
- 1997-05-20 CA CA002253406A patent/CA2253406A1/en not_active Abandoned
- 1997-05-20 PL PL97330195A patent/PL330195A1/xx unknown
- 1997-05-20 CZ CZ983846A patent/CZ384698A3/cs unknown
- 1997-05-20 DE DE69718786T patent/DE69718786T2/de not_active Expired - Fee Related
- 1997-05-20 SI SI9730482T patent/SI0906294T1/xx unknown
- 1997-05-20 KR KR1019980709719A patent/KR20000016151A/ko not_active Application Discontinuation
- 1997-05-20 CN CN97195015A patent/CN1074764C/zh not_active Expired - Fee Related
- 1997-05-20 NZ NZ332737A patent/NZ332737A/en unknown
- 1997-05-20 EA EA199800987A patent/EA001486B1/ru not_active IP Right Cessation
- 1997-05-20 WO PCT/US1997/008524 patent/WO1997045419A1/en not_active Application Discontinuation
- 1997-05-20 EP EP97925651A patent/EP0906294B1/en not_active Expired - Lifetime
- 1997-05-20 EE EE9800417A patent/EE03686B1/xx not_active IP Right Cessation
- 1997-05-22 HN HN1997000075A patent/HN1997000075A/es unknown
- 1997-05-27 AR ARP970102249A patent/AR008372A1/es unknown
- 1997-05-28 PE PE1997000432A patent/PE69398A1/es not_active Application Discontinuation
- 1997-05-28 TW TW086107221A patent/TW542833B/zh active
- 1997-05-28 SV SV1997000047A patent/SV1997000047A/es not_active Application Discontinuation
- 1997-05-28 ID IDP971778A patent/ID17266A/id unknown
- 1997-05-28 CO CO97029474A patent/CO4940505A1/es unknown
- 1997-05-28 UY UY24569A patent/UY24569A1/es not_active Application Discontinuation
- 1997-05-28 PA PA19978431101A patent/PA8431101A1/es unknown
- 1997-05-29 HR HR970301A patent/HRP970301B1/xx not_active IP Right Cessation
-
1998
- 1998-11-26 BG BG102959A patent/BG64049B1/bg unknown
- 1998-11-27 NO NO19985531A patent/NO312296B1/no not_active IP Right Cessation
-
1999
- 1999-10-28 HK HK99104867A patent/HK1019737A1/xx not_active IP Right Cessation
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AU2018214105B2 (en) | Pyridone Amides as Modulators of Sodium Channels | |
CN110352188B (zh) | 氟代烯丙胺衍生物及其用途 | |
SK282703B6 (sk) | Benzoxazinónový derivát, jeho použitie a farmaceutický prostriedok na jeho báze | |
FI96857C (fi) | Menetelmä valmistaa farmakologisesti käyttökelpoista tiatsoliyhdistettä | |
IE62113B1 (en) | Thiadiazinones | |
CA2480384A1 (en) | Phenanthridinones as parp inhibitors | |
IE46652B1 (en) | 4-amino-6,7-dimethoxy-2(4-(1,2,3-thiadiazole carbonyl)-pioerazin-1-yl)quinazolines | |
IL191360A (en) | Compounds Containing 5-Phenyl-6,3-Dihydro-2-Oxo-H6- [1,3,4] Thadiazines Converted, Process for their Preparation and Use for Drug Preparation | |
CA2929188C (en) | Quinazoline derivatives as tam family kinase inhibitors | |
JPH05194441A (ja) | 新規な置換3−ピペラジニルアルキル−2,3−ジヒドロ−4h−1,3−ベンゾオキサジン−4−オン、その製造法および治療用途 | |
US5919784A (en) | Heterocyclic aminomethyl compounds | |
FI85484B (fi) | Foerfarande foer framstaellning av antipsykotiska pyridinylpiperazinderivat som innehaoller en kondenserad ring. | |
EP0401707B1 (en) | Heterocyclic triazin or triazolo compounds having serotonin 2-receptor antagonistic activity | |
CN108017633A (zh) | N-[5-(嘧啶-2-氨基)-2,4-二取代苯基]-2-氟代丙烯酰胺衍生物及应用 | |
EP0577217A1 (en) | Tetrazolyl-(phenoxy and phenoxyalkyl) piperidininylpyridazines as antiviral agents | |
US6177422B1 (en) | Benzoxazinone dopamine D4 receptor antagonists | |
FI71932B (fi) | Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 1,2,4-oxadiazinderivat | |
DK156059B (da) | Analogifremgangsmaade til fremstilling af guanidinderivater | |
SK287333B6 (sk) | Derivát piperazinylkarbonylchinolínu alebo piperazinylkarbonylizochinolínu, spôsob jeho prípravy, jeho použitie a farmaceutický prostriedok s jeho obsahom | |
CZ8096A3 (en) | Derivative of 3-alkoxycarbonylthiadiazinone, process of its preparation and pharmaceutical composition containing thereof | |
WO2013076590A1 (en) | Benzothiazine compounds as h3 receptor ligands | |
US5922719A (en) | Coumarin dopamine D4 receptor antagonists | |
DK149106B (da) | Analogifremgangsmaade til fremstilling af 1,2,4-oxadiazinderivater eller farmaceutisk acceptable syreadditionssalte eller kvaternaere salte deraf samt 1,2,4-oxadiazolin-5-oner til anvendelse ved fremgangsmaaden | |
NL9301524A (nl) | 1,3,4-Benztriazepin-5(4H)-on derivaten en werkwijze voor het bereiden daarvan. | |
JPS6293272A (ja) | ピペラジン誘導体及びその製法 |