HN1997000075A - Antagonistas de receptor de benzoxazinona dofamina d4 - Google Patents

Antagonistas de receptor de benzoxazinona dofamina d4

Info

Publication number
HN1997000075A
HN1997000075A HN1997000075A HN1997000075A HN1997000075A HN 1997000075 A HN1997000075 A HN 1997000075A HN 1997000075 A HN1997000075 A HN 1997000075A HN 1997000075 A HN1997000075 A HN 1997000075A HN 1997000075 A HN1997000075 A HN 1997000075A
Authority
HN
Honduras
Prior art keywords
dofamine
benzoxazinone
receptor antagonists
present
antagonists
Prior art date
Application number
HN1997000075A
Other languages
English (en)
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of HN1997000075A publication Critical patent/HN1997000075A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D265/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/281,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/341,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/361,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A ANTAGONISTAS DE RECEPTOR DE BENZOXAZINONA DOFAMINA D4
HN1997000075A 1996-05-29 1997-05-22 Antagonistas de receptor de benzoxazinona dofamina d4 HN1997000075A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1838396P 1996-05-29 1996-05-29
US4020897P 1997-03-06 1997-03-06

Publications (1)

Publication Number Publication Date
HN1997000075A true HN1997000075A (es) 1997-07-30

Family

ID=26691052

Family Applications (1)

Application Number Title Priority Date Filing Date
HN1997000075A HN1997000075A (es) 1996-05-29 1997-05-22 Antagonistas de receptor de benzoxazinona dofamina d4

Country Status (37)

Country Link
EP (1) EP0906294B1 (es)
JP (1) JP2000511534A (es)
KR (1) KR20000016151A (es)
CN (1) CN1074764C (es)
AR (1) AR008372A1 (es)
AT (1) ATE231846T1 (es)
AU (1) AU731104B2 (es)
BG (1) BG64049B1 (es)
BR (1) BR9709630A (es)
CA (1) CA2253406A1 (es)
CO (1) CO4940505A1 (es)
CZ (1) CZ384698A3 (es)
DE (1) DE69718786T2 (es)
DK (1) DK0906294T3 (es)
EA (1) EA001486B1 (es)
EE (1) EE03686B1 (es)
ES (1) ES2191180T3 (es)
GE (1) GEP20012389B (es)
HK (1) HK1019737A1 (es)
HN (1) HN1997000075A (es)
HR (1) HRP970301B1 (es)
HU (1) HUP9903758A3 (es)
ID (1) ID17266A (es)
IL (1) IL126895A (es)
NO (1) NO312296B1 (es)
NZ (1) NZ332737A (es)
PA (1) PA8431101A1 (es)
PE (1) PE69398A1 (es)
PL (1) PL330195A1 (es)
PT (1) PT906294E (es)
RO (1) RO120845B1 (es)
SI (1) SI0906294T1 (es)
SK (1) SK282703B6 (es)
SV (1) SV1997000047A (es)
TW (1) TW542833B (es)
UY (1) UY24569A1 (es)
WO (1) WO1997045419A1 (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6177422B1 (en) 1996-05-29 2001-01-23 Warner-Lambert Company Benzoxazinone dopamine D4 receptor antagonists
GB9801392D0 (en) * 1998-01-22 1998-03-18 Smithkline Beecham Plc Novel compounds
US6291463B1 (en) 1998-06-30 2001-09-18 Neurogen Corporation 1-(Benzothiazol-2-yl)-4-(1-phenylmethyl) piperazines: dopamine receptor subtype specific ligands
WO2000000482A1 (en) * 1998-06-30 2000-01-06 Neurogen Corporation 1-(benzothiazol-2-yl)-4-(1-phenylmethyl)piperazines: dopamine receptor subtype specific ligands
EP1091949A2 (en) * 1998-06-30 2001-04-18 Neurogen Corporation 6-(4-arylalkylpiperazin-1-yl)benzodioxane and 6-(4-arylalkylpiperazin-1-yl)chromane derivatives: dopamine receptor subtype specific ligands
US6177566B1 (en) 1998-06-30 2001-01-23 Neurogen Corporation 6-(4-arylalkylpiperazin-1-yl) benzodioxane and 6-(4-arylalkylpiperazin-1-yl) chromane derivatives: dopamine receptor subtype specific ligands
DE19844291A1 (de) * 1998-09-18 2000-03-23 Schering Ag Benzoxazin- und Benzothiazin-Derivate und deren Verwendung in Arzneimitteln
GB9912411D0 (en) * 1999-05-28 1999-07-28 Pfizer Ltd Compounds useful in therapy
DE60127434T2 (de) 2000-10-26 2007-11-29 Smithkline Beecham P.L.C., Brentford Benzoxazinonderivative, deren herstellung und verwendung
GB0203804D0 (en) 2002-02-18 2002-04-03 Glaxo Group Ltd Compounds
GB0209244D0 (en) * 2002-04-23 2002-06-05 Glaxo Group Ltd Compounds
GB0227240D0 (en) * 2002-11-21 2002-12-31 Glaxo Group Ltd Compounds
ES2232292B1 (es) * 2003-07-30 2006-11-01 Laboratorios Del Dr. Esteve, S.A. Compuestos sulfonamidicos derivados de benzoxazinona, su preparacion y uso como medicamentos.
CN100455573C (zh) * 2005-11-11 2009-01-28 华东理工大学 一种制备1,4-苯并噁唑嗪-3-酮化合物的微波合成方法
KR200482995Y1 (ko) 2015-08-19 2017-03-23 이현진 물 공급부를 구비하는 얼음 트레이
CA3215823A1 (en) * 2021-04-23 2022-10-27 Peng Gao Heterocyclic derivative inhibitor and preparation method therefor and application thereof
WO2023207283A1 (en) * 2022-04-28 2023-11-02 Ningbo Newbay Technology Development Co., Ltd Compounds as parp1 inhibitiors

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4613598A (en) * 1984-03-13 1986-09-23 Mitsubishi Chemical Industries Limited Piperazine derivatives and their acid addition salts
EP0233728A1 (en) * 1986-02-11 1987-08-26 Takeda Chemical Industries, Ltd. 1,4-Benzoxazine derivatives their production and use
US5523299A (en) * 1992-08-06 1996-06-04 Smithkline Beecham Plc 5-(2-oxyphenyl)-pyrrole derivatives as dopamine D3 receptor antagonists

Also Published As

Publication number Publication date
JP2000511534A (ja) 2000-09-05
SI0906294T1 (en) 2003-04-30
WO1997045419A1 (en) 1997-12-04
ES2191180T3 (es) 2003-09-01
EE03686B1 (et) 2002-04-15
AU3072797A (en) 1998-01-05
TW542833B (en) 2003-07-21
SV1997000047A (es) 1998-08-13
NO312296B1 (no) 2002-04-22
DE69718786D1 (de) 2003-03-06
GEP20012389B (en) 2001-03-25
CA2253406A1 (en) 1997-12-04
BG64049B1 (bg) 2003-11-28
ATE231846T1 (de) 2003-02-15
NO985531L (no) 1998-11-27
HUP9903758A2 (hu) 2000-06-28
PT906294E (pt) 2003-06-30
EE9800417A (et) 1999-06-15
BR9709630A (pt) 1999-08-10
PE69398A1 (es) 1998-12-02
HRP970301B1 (en) 2002-08-31
KR20000016151A (ko) 2000-03-25
CZ384698A3 (cs) 1999-03-17
EA001486B1 (ru) 2001-04-23
PL330195A1 (en) 1999-04-26
DK0906294T3 (da) 2003-05-05
ID17266A (id) 1997-12-18
BG102959A (en) 1999-08-31
AR008372A1 (es) 2000-01-19
SK282703B6 (sk) 2002-11-06
EA199800987A1 (ru) 1999-06-24
EP0906294B1 (en) 2003-01-29
CO4940505A1 (es) 2000-07-24
EP0906294A1 (en) 1999-04-07
SK162798A3 (en) 1999-06-11
RO120845B1 (ro) 2006-08-30
UY24569A1 (es) 2001-08-27
NO985531D0 (no) 1998-11-27
NZ332737A (en) 2000-06-23
AU731104B2 (en) 2001-03-22
HK1019737A1 (en) 2000-02-25
CN1219930A (zh) 1999-06-16
IL126895A (en) 2001-06-14
DE69718786T2 (de) 2003-10-23
IL126895A0 (en) 1999-09-22
HUP9903758A3 (en) 2000-07-28
CN1074764C (zh) 2001-11-14
HRP970301A2 (en) 1998-04-30
PA8431101A1 (es) 2001-12-14

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