SK282237B6 - Deriváty 1-aryl-2-acylaminoetánu, spôsob ich prípravy a farmaceutický prostriedok, ktorý ich obsahuje - Google Patents

Deriváty 1-aryl-2-acylaminoetánu, spôsob ich prípravy a farmaceutický prostriedok, ktorý ich obsahuje Download PDF

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SK282237B6
SK282237B6 SK1139-97A SK113997A SK282237B6 SK 282237 B6 SK282237 B6 SK 282237B6 SK 113997 A SK113997 A SK 113997A SK 282237 B6 SK282237 B6 SK 282237B6
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Slovakia
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carbon atoms
group
lower alkyl
substituted
unsubstituted
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SK1139-97A
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English (en)
Slovak (sk)
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SK113997A3 (en
Inventor
Marc Gerspacher
Sprecher Andreas Von
Silvio Roggo
Robert Mah
Silvio Ofner
Siem Jacob Veenstra
Claudia Betschart
Yves Auberson
Walter Schilling
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Novartis Ag
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Publication of SK113997A3 publication Critical patent/SK113997A3/sk
Publication of SK282237B6 publication Critical patent/SK282237B6/sk

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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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    • C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
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    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
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    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
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    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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SK1139-97A 1995-02-22 1996-02-09 Deriváty 1-aryl-2-acylaminoetánu, spôsob ich prípravy a farmaceutický prostriedok, ktorý ich obsahuje SK282237B6 (sk)

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EP95810117 1995-02-22
PCT/EP1996/000555 WO1996026183A1 (en) 1995-02-22 1996-02-09 1-aryl-2-acylamino-ethane compounds and their use as neurokinin especially neurokinin 1 antagonists

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AU3149297A (en) * 1996-05-24 1997-12-09 Eli Lilly And Company Methods of treating hypertension
MY132550A (en) * 1996-08-22 2007-10-31 Novartis Ag Acylaminoalkenylene-amide derivatives as nk1 and nk2 antogonists
GB0010958D0 (en) * 2000-05-05 2000-06-28 Novartis Ag Organic compounds
GB0203061D0 (en) * 2002-02-08 2002-03-27 Novartis Ag Organic compounds
GB0224788D0 (en) * 2002-10-24 2002-12-04 Novartis Ag Organic compounds
GB2394417A (en) * 2002-10-24 2004-04-28 Novartis Ag Solid dispersion comprising a piperidine substance P antagonist and a carrier
EP1691814B9 (en) * 2003-12-01 2013-02-20 Cambridge Enterprise Limited Anti-inflammatory agents
US20090156465A1 (en) 2005-12-30 2009-06-18 Sattigeri Jitendra A Derivatives of beta-amino acid as dipeptidyl peptidase-iv inhibitors
GB0607532D0 (en) * 2006-04-13 2006-05-24 Novartis Ag Organic compounds
JO2630B1 (en) * 2006-04-13 2012-06-17 نوفارتيس ايه جي Organic compounds
JP4983616B2 (ja) 2008-01-16 2012-07-25 ソニー株式会社 熱転写記録媒体
ES2672099T3 (es) 2011-07-04 2018-06-12 Irbm - Science Park S.P.A. Antagonistas del receptor NK-1 para el tratamiento de la neovascularización corneal
BR112016017313A2 (pt) * 2014-02-18 2017-08-08 Daiichi Sankyo Co Ltd Composto, composição farmacêutica, inibidor da atividade da atpase de um complexo tip48/tip49, e, agentes antitumor e terapêutico para um tumor
AU2019223237A1 (en) 2018-02-26 2020-09-03 Ospedale San Raffaele S.R.L. NK-1 antagonists for use in the treatment of ocular pain
RU2697414C1 (ru) * 2018-05-11 2019-08-14 Общество с ограниченной ответственностью "АЙ БИ ДИ Терапевтикс" Новый антагонист тахикининовых рецепторов и его применение
US11575807B2 (en) 2020-01-20 2023-02-07 Monomer Software LLC Optical device field of view cleaning apparatus
WO2021180885A1 (en) 2020-03-11 2021-09-16 Ospedale San Raffaele S.R.L. Treatment of stem cell deficiency

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EP0532546B1 (en) * 1990-05-10 1998-03-18 Bechgaard International Research And Development A/S A pharmaceutical preparation containing n-glycofurols and n-ethylene glycols
US5472978A (en) * 1991-07-05 1995-12-05 Merck Sharp & Dohme Ltd. Aromatic compounds, pharmaceutical compositions containing them and their use in therapy
MY110227A (en) * 1991-08-12 1998-03-31 Ciba Geigy Ag 1-acylpiperindine compounds.
US5217996A (en) * 1992-01-22 1993-06-08 Ciba-Geigy Corporation Biaryl substituted 4-amino-butyric acid amides

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IL117209A (en) 2001-01-11
EP0810991A1 (en) 1997-12-10
FI120304B (fi) 2009-09-15
GR3030626T3 (en) 1999-10-29
HUP9800051A3 (en) 1998-08-28
CZ266297A3 (en) 1997-11-12
EP0810991B1 (en) 1999-04-14
FI973221A0 (fi) 1997-08-04
EA002348B1 (ru) 2002-04-25
KR100389253B1 (ko) 2003-08-19
SK113997A3 (en) 1998-02-04
NZ300942A (en) 1998-12-23
MX9706394A (es) 1997-11-29
HU226562B1 (en) 2009-04-28
NO325605B1 (no) 2008-06-23
KR19980702391A (ko) 1998-07-15
AU4623396A (en) 1996-09-11
AU701560B2 (en) 1999-01-28
WO1996026183A1 (en) 1996-08-29
FI973221A (fi) 1997-10-20
US5929067A (en) 1999-07-27
DK0810991T3 (da) 1999-10-25
HUP9800051A2 (hu) 1998-05-28
NO973857L (no) 1997-10-01
BR9607335A (pt) 1997-11-25
CN1081625C (zh) 2002-03-27
JP3506714B2 (ja) 2004-03-15
CA2213080A1 (en) 1996-08-29
EA199900385A1 (ru) 1999-10-28
IL117209A0 (en) 1996-06-18
ZA961364B (en) 1996-08-22
DE69602087T2 (de) 1999-09-09
PL184226B1 (pl) 2002-09-30
JPH11500436A (ja) 1999-01-12
CN1175944A (zh) 1998-03-11
PL322001A1 (en) 1998-01-05
NO973857D0 (no) 1997-08-21
ES2132882T3 (es) 1999-08-16
CY2198B1 (en) 2002-11-08
TR199700834T1 (xx) 1998-01-21
DE69602087D1 (de) 1999-05-20
ATE178886T1 (de) 1999-04-15
CZ288345B6 (en) 2001-05-16
CA2213080C (en) 2007-11-13

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