SK282047B6 - Taxoidy, spôsoby ich prípravy a farmaceutická kompozícia obsahujúca tieto taxoidy - Google Patents

Taxoidy, spôsoby ich prípravy a farmaceutická kompozícia obsahujúca tieto taxoidy Download PDF

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Publication number
SK282047B6
SK282047B6 SK1333-97A SK133397A SK282047B6 SK 282047 B6 SK282047 B6 SK 282047B6 SK 133397 A SK133397 A SK 133397A SK 282047 B6 SK282047 B6 SK 282047B6
Authority
SK
Slovakia
Prior art keywords
group
carbon atoms
formula
alkyl
phenyl
Prior art date
Application number
SK1333-97A
Other languages
English (en)
Slovak (sk)
Other versions
SK133397A3 (en
Inventor
Herv Bouchard
Jean-Dominique Bourzat
Alain Commeron
Original Assignee
Rhone-Poulenc Rorer S. A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone-Poulenc Rorer S. A. filed Critical Rhone-Poulenc Rorer S. A.
Publication of SK133397A3 publication Critical patent/SK133397A3/sk
Publication of SK282047B6 publication Critical patent/SK282047B6/sk

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D305/00Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
SK1333-97A 1995-04-03 1996-04-01 Taxoidy, spôsoby ich prípravy a farmaceutická kompozícia obsahujúca tieto taxoidy SK282047B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9503868A FR2732342B1 (fr) 1995-04-03 1995-04-03 Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
PCT/FR1996/000487 WO1996031493A1 (fr) 1995-04-03 1996-04-01 Nouveaux taxoïdes, leur preparation et les compositions pharmaceutiques qui les contiennent

Publications (2)

Publication Number Publication Date
SK133397A3 SK133397A3 (en) 1998-02-04
SK282047B6 true SK282047B6 (sk) 2001-10-08

Family

ID=9477663

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1333-97A SK282047B6 (sk) 1995-04-03 1996-04-01 Taxoidy, spôsoby ich prípravy a farmaceutická kompozícia obsahujúca tieto taxoidy

Country Status (32)

Country Link
US (1) US5959125A (ja)
EP (1) EP0821680B1 (ja)
JP (1) JPH11504004A (ja)
KR (1) KR19980703520A (ja)
CN (1) CN1073106C (ja)
AP (1) AP784A (ja)
AR (1) AR002730A1 (ja)
AT (1) ATE195940T1 (ja)
AU (1) AU703918B2 (ja)
BG (1) BG62964B1 (ja)
BR (1) BR9604799A (ja)
CA (1) CA2214322C (ja)
CZ (1) CZ287430B6 (ja)
DE (1) DE69610085T2 (ja)
DK (1) DK0821680T3 (ja)
EA (1) EA000726B1 (ja)
ES (1) ES2151155T3 (ja)
FR (1) FR2732342B1 (ja)
GE (1) GEP19991872B (ja)
GR (1) GR3034203T3 (ja)
HU (1) HUP9802042A3 (ja)
IL (1) IL117760A (ja)
MX (1) MX9707427A (ja)
NO (1) NO974563L (ja)
NZ (1) NZ305898A (ja)
PL (1) PL322581A1 (ja)
PT (1) PT821680E (ja)
RO (1) RO115879B1 (ja)
SK (1) SK282047B6 (ja)
TW (1) TW347389B (ja)
WO (1) WO1996031493A1 (ja)
ZA (1) ZA962633B (ja)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6495579B1 (en) 1996-12-02 2002-12-17 Angiotech Pharmaceuticals, Inc. Method for treating multiple sclerosis
FR2764118B1 (fr) * 1997-05-30 2000-08-04 Thomson Csf Transistor bipolaire stabilise avec elements isolants electriques
US6156789A (en) * 1998-03-17 2000-12-05 Rhone-Poulenc Rorer S.A. Method for treating abnormal cell proliferation in the brain
EP1176957A1 (en) * 1999-05-03 2002-02-06 Aventis Pharma S.A. Method for treating abnormal cell proliferation in the brain
GEP20043239B (en) 2000-02-02 2004-05-25 Florida State Univ Research Foundation Us C10 Carbonate Substituted Taxanes as Antitumor Agents
US6649632B2 (en) 2000-02-02 2003-11-18 Fsu Research Foundation, Inc. C10 ester substituted taxanes
US6596737B2 (en) * 2000-02-02 2003-07-22 Fsu Research Foundation, Inc. C10 carbamoyloxy substituted taxanes
JP2004339475A (ja) * 2003-02-03 2004-12-02 Merck Patent Gmbh フッ化物、オキシフッ化物、フルオロ硫化物および/またはオキシフルオロ硫化物に基づく真珠光沢顔料
US20080107721A1 (en) * 2003-05-20 2008-05-08 Jonathan Lewis Combination Chemotherapy Comprising A Liposomal Platinum Complex
HN2005000054A (es) * 2004-02-13 2009-02-18 Florida State University Foundation Inc Taxanos sustituidos con esteres de ciclopentilo en c10
MX2007009748A (es) * 2005-02-14 2007-09-26 Univ Florida State Res Found Composiciones de taxano sustituidas con esteres ciclopropilicos en c10.
US8242166B2 (en) * 2008-03-31 2012-08-14 Florida State University Research Foundation, Inc. C(10) ethyl ester and C(10) cyclopropyl ester substituted taxanes

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5254580A (en) * 1993-01-19 1993-10-19 Bristol-Myers Squibb Company 7,8-cyclopropataxanes
DK0577082T3 (da) * 1992-07-01 1996-05-06 Bristol Myers Squibb Co Fluortaxoler med antitumor aktivitet
FR2698871B1 (fr) * 1992-12-09 1995-02-24 Rhone Poulenc Rorer Sa Nouveau taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.
MX9307777A (es) * 1992-12-15 1994-07-29 Upjohn Co 7-HALO-Y 7ß, 8ß-METANO-TAXOLES, USO ANTINEOPLASTICO Y COMPOSICIONES FARMACEUTICAS QUE LOS CONTIENEN.

Also Published As

Publication number Publication date
DK0821680T3 (da) 2000-11-20
EA199700288A1 (ru) 1998-04-30
HUP9802042A3 (en) 2001-02-28
DE69610085T2 (de) 2001-01-11
NZ305898A (en) 1998-12-23
EA000726B1 (ru) 2000-02-28
CA2214322A1 (fr) 1996-10-10
NO974563D0 (no) 1997-10-02
RO115879B1 (ro) 2000-07-28
CN1073106C (zh) 2001-10-17
AP9701094A0 (en) 1997-10-31
FR2732342B1 (fr) 1997-04-30
IL117760A (en) 2001-11-25
JPH11504004A (ja) 1999-04-06
AU703918B2 (en) 1999-04-01
FR2732342A1 (fr) 1996-10-04
IL117760A0 (en) 1996-08-04
PT821680E (pt) 2000-12-29
SK133397A3 (en) 1998-02-04
GR3034203T3 (en) 2000-11-30
HUP9802042A2 (hu) 2000-06-28
CZ287430B6 (en) 2000-11-15
AP784A (en) 1999-11-22
CZ310997A3 (cs) 1998-01-14
ATE195940T1 (de) 2000-09-15
EP0821680B1 (fr) 2000-08-30
ZA962633B (en) 1996-10-07
DE69610085D1 (de) 2000-10-05
NO974563L (no) 1997-11-24
BG62964B1 (bg) 2000-12-29
BG101940A (en) 1998-11-30
CN1179777A (zh) 1998-04-22
EP0821680A1 (fr) 1998-02-04
MX9707427A (es) 1998-02-28
AU5402896A (en) 1996-10-23
KR19980703520A (ko) 1998-11-05
BR9604799A (pt) 1999-04-06
CA2214322C (fr) 2007-01-30
PL322581A1 (en) 1998-02-02
AR002730A1 (es) 1998-04-29
WO1996031493A1 (fr) 1996-10-10
GEP19991872B (en) 1999-12-06
US5959125A (en) 1999-09-28
ES2151155T3 (es) 2000-12-16
TW347389B (en) 1998-12-11

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