SK280628B6 - Farmaceutický prostriedok na liečbu periodontálneh - Google Patents

Farmaceutický prostriedok na liečbu periodontálneh Download PDF

Info

Publication number
SK280628B6
SK280628B6 SK727-94A SK72794A SK280628B6 SK 280628 B6 SK280628 B6 SK 280628B6 SK 72794 A SK72794 A SK 72794A SK 280628 B6 SK280628 B6 SK 280628B6
Authority
SK
Slovakia
Prior art keywords
alendronate
pharmaceutical composition
periodontal disease
treatment
periodontal
Prior art date
Application number
SK727-94A
Other languages
English (en)
Slovak (sk)
Other versions
SK72794A3 (en
Inventor
Barry J. Gertz
Gideon A. Rodan
Original Assignee
Merck & Co.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co. filed Critical Merck & Co.
Publication of SK72794A3 publication Critical patent/SK72794A3/sk
Publication of SK280628B6 publication Critical patent/SK280628B6/sk

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SK727-94A 1991-12-17 1992-12-08 Farmaceutický prostriedok na liečbu periodontálneh SK280628B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/808,701 US5270365A (en) 1991-12-17 1991-12-17 Prevention and treatment of periodontal disease with alendronate
PCT/US1992/010534 WO1993011774A1 (en) 1991-12-17 1992-12-08 Treatment of periodontal disease with alendronate

Publications (2)

Publication Number Publication Date
SK72794A3 SK72794A3 (en) 1995-04-12
SK280628B6 true SK280628B6 (sk) 2000-05-16

Family

ID=25199466

Family Applications (1)

Application Number Title Priority Date Filing Date
SK727-94A SK280628B6 (sk) 1991-12-17 1992-12-08 Farmaceutický prostriedok na liečbu periodontálneh

Country Status (22)

Country Link
US (1) US5270365A (hu)
EP (1) EP0617624B1 (hu)
JP (1) JP2825654B2 (hu)
KR (1) KR100258667B1 (hu)
AT (1) ATE150646T1 (hu)
AU (1) AU675417B2 (hu)
CA (1) CA2122498A1 (hu)
CY (1) CY2054B1 (hu)
CZ (1) CZ282902B6 (hu)
DE (1) DE69218624T2 (hu)
DK (1) DK0617624T3 (hu)
ES (1) ES2100519T3 (hu)
GR (1) GR3022951T3 (hu)
HK (1) HK1000114A1 (hu)
HU (1) HU221807B1 (hu)
IL (1) IL104109A (hu)
LV (1) LV12084B (hu)
NO (1) NO306197B1 (hu)
NZ (1) NZ246274A (hu)
SK (1) SK280628B6 (hu)
WO (1) WO1993011774A1 (hu)
ZA (1) ZA929712B (hu)

Families Citing this family (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW237386B (hu) * 1992-04-15 1995-01-01 Ciba Geigy
US5403829A (en) * 1993-03-24 1995-04-04 Leiras Oy Use of bisphosphonates in endo-osteal bone surgery
FR2703590B1 (fr) * 1993-04-05 1995-06-30 Sanofi Elf Utilisation de derives d'acide bisphosphonique pour la preparation de medicaments destines a favoriser la reparation osseuse .
US5854227A (en) * 1994-03-04 1998-12-29 Hartmann; John F. Therapeutic derivatives of diphosphonates
WO1995028145A1 (en) * 1994-04-18 1995-10-26 The Procter & Gamble Company Iontophoretic delivery of bisphosphonates to the alveolar bone
US5646134A (en) * 1994-04-21 1997-07-08 Merck & Co., Inc. Alendronate therapy to prevent loosening of, or pain associated with, orthopedic implant devices
US5462932A (en) * 1994-05-17 1995-10-31 Merck & Co., Inc. Oral liquid alendronate formulations
US5780455A (en) * 1994-08-24 1998-07-14 Merck & Co., Inc. Intravenous alendronate formulations
US6008206A (en) * 1994-09-21 1999-12-28 Merck & Co., Inc. Sodium alendronate preparation for local administration
JP3411690B2 (ja) * 1994-09-21 2003-06-03 帝人株式会社 局所投与用アレンドロン酸ナトリウム製剤
KR19980702210A (ko) * 1995-02-17 1998-07-15 폴락 돈나 엘 비척추골 골절의 위험률을 감소시키는 방법
CA2219354A1 (en) * 1995-05-12 1996-11-14 Merck & Co., Inc. Prevention of tooth loss by the administration of alendronate or its salts
US6117856A (en) * 1996-02-14 2000-09-12 Binderman; Itzhak Topical bisphosphonates for prevention of bone resorption
ATE240737T1 (de) * 1996-02-14 2003-06-15 Itzhak Binderman Topische bisphosphonate zur verhinderung der knochenresorption
EP1378234A1 (en) * 1996-05-17 2004-01-07 MERCK & CO. INC. Effervescent bisphosphonate formulation
AU712710B2 (en) * 1996-05-17 1999-11-11 Merck Sharp & Dohme Corp. Effervescent bisphosphonate formulation
US5853759A (en) * 1996-05-17 1998-12-29 Merck & Co.. Inc. Effervescent alendronate formulation
PL332496A1 (en) * 1996-10-04 1999-09-13 Merck & Co Inc Liquid alendronate preparations
US5773429A (en) * 1996-12-11 1998-06-30 Fuisz Technologies Ltd. Drug combination for treating calcium loss
US20010031244A1 (en) * 1997-06-13 2001-10-18 Chiesi Farmaceutici S.P.A. Pharmaceutical aerosol composition
US5994329A (en) 1997-07-22 1999-11-30 Merck & Co., Inc. Method for inhibiting bone resorption
CN1166365C (zh) * 1997-07-22 2004-09-15 麦克公司 阿仑膦酸的药物组合物及其在制备抑制人的骨吸收的药物中的用途
US6432932B1 (en) 1997-07-22 2002-08-13 Merck & Co., Inc. Method for inhibiting bone resorption
FR2784031B1 (fr) * 1998-10-02 2002-02-01 Sanofi Elf Utilisation de derives de l'acide bisphosphonique pour la preparation d'un medicament destine au traitement des boiteries
US6331533B1 (en) * 1998-11-16 2001-12-18 Merck & Co., Inc. Method for inhibiting dental resorptive lesions
CA2356262A1 (en) * 1998-12-23 2000-07-06 Jomaa Pharmaka Gmbh Use of bisphosphonates for the prevention and treatment of infectious processes
US6315566B1 (en) 1999-05-18 2001-11-13 3M Innovative Properties Company Dental materials
US6143919A (en) * 1999-05-18 2000-11-07 3M Innovative Properties Company Polymerizable acidic compounds and methods of preparation
PL196485B1 (pl) * 2000-05-11 2008-01-31 Inst Farmaceutyczny Stała doustna kompozycja farmaceutyczna zawierająca aminową pochodną kwasu bisfosfonowego i sposób jej wytwarzania
GB0029111D0 (en) * 2000-11-29 2001-01-10 Novartis Ag Organic compounds
US20030216358A1 (en) * 2001-07-05 2003-11-20 Muchmore Douglas Boyer Method for enhancing bone mineral density gain
US20040053968A1 (en) * 2001-12-28 2004-03-18 Hartman George D. Methods and compositions for treating peridontal disease
US7960054B2 (en) * 2002-01-10 2011-06-14 Excellatron Solid State Llc Packaged thin film batteries
US20070094865A1 (en) * 2002-01-10 2007-05-03 Ji-Guang Zhang Packaged thin film batteries and methods of packaging thin film batteries
US7488496B2 (en) * 2002-03-06 2009-02-10 Christer Rosen Effervescent compositions comprising bisphosphonates and methods related thereto
WO2003086415A1 (en) * 2002-04-05 2003-10-23 Merck & Co., Inc. Method for inhibiting bone resorption with an alendronate and vitamin d formulation
FR2838339B1 (fr) * 2002-04-12 2005-06-24 Univ Angers Derives poly-phosphonates pour compositions dentifrices
US20040137058A1 (en) * 2002-07-09 2004-07-15 Katdare Ashok V. Effervescent bisphosphonate formulation
US20050142185A1 (en) * 2003-12-29 2005-06-30 Beleno Alfredo B. Softgel formulations of bisphosphonates bone resorption inhibitors
US20060034921A1 (en) * 2004-01-05 2006-02-16 Katdare Ashok V Effervescent bisphosphonate formulation
US20050181043A1 (en) * 2004-02-12 2005-08-18 Indranil Nandi Alendronate salt tablet compositions
US20080070087A1 (en) * 2004-02-20 2008-03-20 Excellatron Solid State, Llc Non-volatile cathodes for lithium oxygen batteries and method of producing same
US20050261250A1 (en) * 2004-05-19 2005-11-24 Merck & Co., Inc., Compositions and methods for inhibiting bone resorption
KR100564628B1 (ko) * 2004-06-16 2006-03-28 삼성전자주식회사 스플릿 게이트형 플래쉬 메모리 소자 및 그 제조방법
US20060134190A1 (en) * 2004-12-16 2006-06-22 Banner Pharmacaps Inc. Formulations of bisphosphonate drugs with improved bioavailability
WO2007044904A2 (en) * 2005-10-11 2007-04-19 Ji-Guang Zhang Method of manufacturing lithium battery
US20070087052A1 (en) * 2005-10-19 2007-04-19 Katdare Ashok V Effervescent bisphosphonate formulation
CN101421865B (zh) 2006-03-10 2012-09-26 埃克塞勒特龙固体公司 空气电池及制造方法
US20090118238A1 (en) * 2007-09-17 2009-05-07 Protia, Llc Deuterium-enriched alendronate
US20120164104A1 (en) 2009-08-03 2012-06-28 Chimerix, Inc. Composition and Methods of Treating Viral Infections and Viral Induced Tumors
US8882740B2 (en) * 2009-12-23 2014-11-11 Stryker Trauma Gmbh Method of delivering a biphosphonate and/or strontium ranelate below the surface of a bone
RU2449761C1 (ru) * 2011-03-09 2012-05-10 Светлана Минифаритовна Алетдинова Способ лечения хронических апикальных периодонтитов
GB201200868D0 (en) 2012-01-19 2012-02-29 Depuy Int Ltd Bone filler composition
US9579360B2 (en) 2012-06-20 2017-02-28 The Trustees Of The University Of Pennsylvania Methods of treating or preventing periodontitis and diseases associated with periodontitis
RU2713257C1 (ru) * 2019-05-06 2020-02-04 Жанна Владимировна Вечеркина Способ лечения хронического апикального периодонтита

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3429963A (en) * 1964-06-09 1969-02-25 Colgate Palmolive Co Dental preparation containing polymeric polyelectrolyte
US4134969A (en) * 1974-02-04 1979-01-16 Henkel Kommanditgesellschaft Auf Aktien (Henkel Kgaa) Method of treatment of calcium disorders using aminoalkane-diphosphonic acids
DE2405254C2 (de) * 1974-02-04 1982-05-27 Henkel KGaA, 4000 Düsseldorf Verwendung von 3-Amino-1-Hydroxypropan-1, 1-diphosphonsäure oder ihrer wasserlöslichen Salze bei der Beeinflußung von Calciumstoffwechselstörungen im menschlichen oder tierischen Körper
US4042679A (en) * 1975-11-07 1977-08-16 Colgate-Palmolive Company Antibacterial oral composition
US4138477A (en) * 1976-05-28 1979-02-06 Colgate Palmolive Company Composition to control mouth odor
US4440779A (en) * 1981-06-30 1984-04-03 Merck & Co., Inc. Tricyclic derivatives of substituted pyrrole acids as analgesic and anti-inflammatory agents
IT1201087B (it) * 1982-04-15 1989-01-27 Gentili Ist Spa Bifosfonati farmacologicamente attivi,procedimento per la loro preparazione e relative composizioni farmaceutiche
US4446052A (en) * 1982-05-17 1984-05-01 The Procter & Gamble Company Aqueous gel containing tricalcium di(1-hydroxy-3-aminopropane-1,1-diphosphonate
US4639338A (en) * 1984-08-06 1987-01-27 Ciba-Geigy Corporation Preparation of crystalline disodium 3-amino-1-hydroxypropane-1,1-diphosphonate pentahydrate
US4647453A (en) * 1984-10-18 1987-03-03 Peritain, Ltd. Treatment for tissue degenerative inflammatory disease
US4677132A (en) * 1986-03-12 1987-06-30 American Home Products Corporation Inhibition of bone resorption by etodolac
EP0274346B1 (de) * 1986-11-21 1991-03-06 Ciba-Geigy Ag Neue Substituiertaminomethandiphosphonsäuren
ATE64397T1 (de) * 1986-11-21 1991-06-15 Ciba Geigy Ag Aromatisch substituierte azacycloalkylalkandiphosphons|uren.
US4973576A (en) * 1987-03-10 1990-11-27 Yamanouchi Pharmaceutical Co., Ltd. Bisphophonic acid derivatives and pharmaceutical compositions containing the same
US4816437A (en) * 1987-06-01 1989-03-28 Trustees Of Boston University Methods for inducing general and localized bone apposition in-vivo
EP0317505A1 (de) * 1987-11-13 1989-05-24 Ciba-Geigy Ag Neue Azacycloalkylalkandiphosphonsäuren
GB8726714D0 (en) * 1987-11-14 1987-12-16 Beecham Group Plc Compounds
EP0320455B1 (de) * 1987-12-11 1993-06-09 Ciba-Geigy Ag Araliphatylaminoalkandiphosphonsäuren
US4877603A (en) * 1987-12-18 1989-10-31 The Procter & Gamble Company Oral compositions
DE3822650A1 (de) * 1988-07-05 1990-02-01 Boehringer Mannheim Gmbh Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel
US4990503A (en) * 1988-08-12 1991-02-05 Yamanouchi Pharmaceutical Co., Ltd. Heterocyclic bisphosphonic acid derivatives
CA2035179C (en) * 1990-01-31 2001-08-14 Gerald S. Brenner Pharmaceutical compositions containing insoluble salts of bisphosphonic acids
GB9008433D0 (en) * 1990-04-12 1990-06-13 Beecham Group Plc Novel compositions
US5019651A (en) * 1990-06-20 1991-05-28 Merck & Co., Inc. Process for preparing 4-amino-1-hydroxybutylidene-1,1-bisphosphonic acid (ABP) or salts thereof

Also Published As

Publication number Publication date
HU9401378D0 (en) 1994-08-29
LV12084B (en) 1998-11-20
LV12084A (lv) 1998-07-20
DE69218624T2 (de) 1997-08-07
JP2825654B2 (ja) 1998-11-18
EP0617624B1 (en) 1997-03-26
HK1000114A1 (en) 1997-12-05
CY2054B1 (en) 1998-04-30
NO942267L (no) 1994-06-16
NO306197B1 (no) 1999-10-04
ATE150646T1 (de) 1997-04-15
KR100258667B1 (ko) 2000-07-01
WO1993011774A1 (en) 1993-06-24
GR3022951T3 (en) 1997-06-30
CZ282902B6 (cs) 1997-11-12
HU221807B1 (hu) 2003-01-28
SK72794A3 (en) 1995-04-12
KR940703676A (ko) 1994-12-12
DK0617624T3 (da) 1997-04-21
DE69218624D1 (de) 1997-04-30
ES2100519T3 (es) 1997-06-16
NO942267D0 (no) 1994-06-16
IL104109A (en) 1997-02-18
HUT68788A (en) 1995-07-28
IL104109A0 (en) 1993-05-13
ZA929712B (en) 1993-06-14
AU3242093A (en) 1993-07-19
JPH07502506A (ja) 1995-03-16
NZ246274A (en) 1997-02-24
CZ148794A3 (en) 1995-03-15
CA2122498A1 (en) 1993-06-24
EP0617624A1 (en) 1994-10-05
AU675417B2 (en) 1997-02-06
US5270365A (en) 1993-12-14

Similar Documents

Publication Publication Date Title
SK280628B6 (sk) Farmaceutický prostriedok na liečbu periodontálneh
US5652227A (en) Inhibition of the degradation of connective tissue matrix protein components in mammals
Chumbley et al. The effect of indomethacin (an aspirin-like drug) on the rate of orthodontic tooth movement
Kim et al. An ultrastructural study of the effects of bisphosphonate administration on osteoclastic bone resorption during relapse of experimentally moved rat molars
ES2269014T3 (es) Procedimiento para inhibir la resorcion osea.
EP0486561B1 (en) Buccal composition containing s(+) flurbiprofen or ketoprofen
Ciancio et al. Cyclosporine-induced gingival hyperplasia and chlorhexidine: a case report.
TW202034927A (zh) 用於治療牙周病之化合物
ES2337545T3 (es) Farmacos para enfermedades periodontales.
US6682718B1 (en) Remedies for periodontosis
WO2018221447A1 (ja) 骨再生剤
US3996377A (en) Medicinal preparation for treating parodontosis and method of treating parodontosis
JP2018090540A (ja) 歯槽骨吸収抑制剤
RU2158582C1 (ru) Способ общего лечения пародонтита
SU1438788A1 (ru) Способ лечени пародонтита
JP2001213780A (ja) 歯周病治療用医薬組成物