ES2100519T3 - Tratamiento de la enfermedad periodontal con alendronato. - Google Patents

Tratamiento de la enfermedad periodontal con alendronato.

Info

Publication number
ES2100519T3
ES2100519T3 ES93900917T ES93900917T ES2100519T3 ES 2100519 T3 ES2100519 T3 ES 2100519T3 ES 93900917 T ES93900917 T ES 93900917T ES 93900917 T ES93900917 T ES 93900917T ES 2100519 T3 ES2100519 T3 ES 2100519T3
Authority
ES
Spain
Prior art keywords
periodontal disease
alendronate
treatment
tridydrate
peridontitis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93900917T
Other languages
English (en)
Inventor
Barry J Gertz
Gideon A Rodan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Application granted granted Critical
Publication of ES2100519T3 publication Critical patent/ES2100519T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

ESTA INVENCION SE REFIERE A UN METODO PARA EL TRATAMIENTO DE LAS ENFERMEDADES PERIODONTALES DE MAMIFEROS, INCLUIDOS LOS SERES HUMANOS, MEDIANTE LA ADMINISTRACION DE UNA CANTIDAD EFECTIVA DE ACIDO 4-AMINO1-HIDROXIBUTILIDEN-1,1-BISFOSFONICO O DE UNA SAL FARMACEUTICAMENTE ACEPTABLE QUE INCLUYA EL TRIDIDRATO DE SAL MONOSODICO (ALENDRONATO) DE LA FORMULA (I). LOS COMPUESTOS SON UTILES PARA EL TRATAMIENTO DE LA PERDIDA OSEA ALVEOLAR ASOCIADA A LA PERIODONTITIS Y A LAS ENFERMEDADES PERIODONTALES.
ES93900917T 1991-12-17 1992-12-08 Tratamiento de la enfermedad periodontal con alendronato. Expired - Lifetime ES2100519T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/808,701 US5270365A (en) 1991-12-17 1991-12-17 Prevention and treatment of periodontal disease with alendronate

Publications (1)

Publication Number Publication Date
ES2100519T3 true ES2100519T3 (es) 1997-06-16

Family

ID=25199466

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93900917T Expired - Lifetime ES2100519T3 (es) 1991-12-17 1992-12-08 Tratamiento de la enfermedad periodontal con alendronato.

Country Status (22)

Country Link
US (1) US5270365A (es)
EP (1) EP0617624B1 (es)
JP (1) JP2825654B2 (es)
KR (1) KR100258667B1 (es)
AT (1) ATE150646T1 (es)
AU (1) AU675417B2 (es)
CA (1) CA2122498A1 (es)
CY (1) CY2054B1 (es)
CZ (1) CZ282902B6 (es)
DE (1) DE69218624T2 (es)
DK (1) DK0617624T3 (es)
ES (1) ES2100519T3 (es)
GR (1) GR3022951T3 (es)
HK (1) HK1000114A1 (es)
HU (1) HU221807B1 (es)
IL (1) IL104109A (es)
LV (1) LV12084B (es)
NO (1) NO306197B1 (es)
NZ (1) NZ246274A (es)
SK (1) SK280628B6 (es)
WO (1) WO1993011774A1 (es)
ZA (1) ZA929712B (es)

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US6008206A (en) * 1994-09-21 1999-12-28 Merck & Co., Inc. Sodium alendronate preparation for local administration
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EP0824341A4 (en) * 1995-05-12 1999-07-07 Merck & Co Inc PREVENTING TOOTH LOSS THROUGH ADMINISTRATION OF ALENDRONATE OR ITS SALTS
US6117856A (en) * 1996-02-14 2000-09-12 Binderman; Itzhak Topical bisphosphonates for prevention of bone resorption
JP2000504718A (ja) * 1996-02-14 2000-04-18 バインダーマン，イザク 骨吸収を予防するための局所用ビスホスホネート
US5853759A (en) * 1996-05-17 1998-12-29 Merck & Co.. Inc. Effervescent alendronate formulation
EP1378234A1 (en) * 1996-05-17 2004-01-07 MERCK & CO. INC. Effervescent bisphosphonate formulation
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US6432932B1 (en) 1997-07-22 2002-08-13 Merck & Co., Inc. Method for inhibiting bone resorption
US5994329A (en) 1997-07-22 1999-11-30 Merck & Co., Inc. Method for inhibiting bone resorption
FR2784031B1 (fr) * 1998-10-02 2002-02-01 Sanofi Elf Utilisation de derives de l'acide bisphosphonique pour la preparation d'un medicament destine au traitement des boiteries
US6331533B1 (en) 1998-11-16 2001-12-18 Merck & Co., Inc. Method for inhibiting dental resorptive lesions
BR9916850A (pt) * 1998-12-23 2001-10-16 Jomaa Pharmaka Gmbh Uso de bisfosfonatos para a profilaxia e tratamento de processos infecciosos
US6315566B1 (en) 1999-05-18 2001-11-13 3M Innovative Properties Company Dental materials
US6143919A (en) * 1999-05-18 2000-11-07 3M Innovative Properties Company Polymerizable acidic compounds and methods of preparation
PL196485B1 (pl) * 2000-05-11 2008-01-31 Inst Farmaceutyczny Stała doustna kompozycja farmaceutyczna zawierająca aminową pochodną kwasu bisfosfonowego i sposób jej wytwarzania
GB0029111D0 (en) * 2000-11-29 2001-01-10 Novartis Ag Organic compounds
US20030216358A1 (en) * 2001-07-05 2003-11-20 Muchmore Douglas Boyer Method for enhancing bone mineral density gain
US20040053968A1 (en) * 2001-12-28 2004-03-18 Hartman George D. Methods and compositions for treating peridontal disease
US20070094865A1 (en) * 2002-01-10 2007-05-03 Ji-Guang Zhang Packaged thin film batteries and methods of packaging thin film batteries
US7960054B2 (en) * 2002-01-10 2011-06-14 Excellatron Solid State Llc Packaged thin film batteries
US7488496B2 (en) * 2002-03-06 2009-02-10 Christer Rosen Effervescent compositions comprising bisphosphonates and methods related thereto
WO2003086415A1 (en) * 2002-04-05 2003-10-23 Merck & Co., Inc. Method for inhibiting bone resorption with an alendronate and vitamin d formulation
FR2838339B1 (fr) * 2002-04-12 2005-06-24 Univ Angers Derives poly-phosphonates pour compositions dentifrices
US20040137058A1 (en) * 2002-07-09 2004-07-15 Katdare Ashok V. Effervescent bisphosphonate formulation
US20050142185A1 (en) * 2003-12-29 2005-06-30 Beleno Alfredo B. Softgel formulations of bisphosphonates bone resorption inhibitors
US20060034921A1 (en) * 2004-01-05 2006-02-16 Katdare Ashok V Effervescent bisphosphonate formulation
US20050181043A1 (en) * 2004-02-12 2005-08-18 Indranil Nandi Alendronate salt tablet compositions
US20080070087A1 (en) * 2004-02-20 2008-03-20 Excellatron Solid State, Llc Non-volatile cathodes for lithium oxygen batteries and method of producing same
US20050261250A1 (en) * 2004-05-19 2005-11-24 Merck & Co., Inc., Compositions and methods for inhibiting bone resorption
KR100564628B1 (ko) * 2004-06-16 2006-03-28 삼성전자주식회사 스플릿 게이트형 플래쉬 메모리 소자 및 그 제조방법
US20060134190A1 (en) * 2004-12-16 2006-06-22 Banner Pharmacaps Inc. Formulations of bisphosphonate drugs with improved bioavailability
WO2007044904A2 (en) * 2005-10-11 2007-04-19 Ji-Guang Zhang Method of manufacturing lithium battery
US20070087052A1 (en) * 2005-10-19 2007-04-19 Katdare Ashok V Effervescent bisphosphonate formulation
CN101421865B (zh) 2006-03-10 2012-09-26 埃克塞勒特龙固体公司 空气电池及制造方法
US20090118238A1 (en) * 2007-09-17 2009-05-07 Protia, Llc Deuterium-enriched alendronate
BR112012002551A2 (pt) 2009-08-03 2017-06-13 Chimerix Inc composição e métodos de tratamento de infecções virais e tumores induzidos por vírus
US8882740B2 (en) * 2009-12-23 2014-11-11 Stryker Trauma Gmbh Method of delivering a biphosphonate and/or strontium ranelate below the surface of a bone
RU2449761C1 (ru) * 2011-03-09 2012-05-10 Светлана Минифаритовна Алетдинова Способ лечения хронических апикальных периодонтитов
GB201200868D0 (en) 2012-01-19 2012-02-29 Depuy Int Ltd Bone filler composition
US9579360B2 (en) 2012-06-20 2017-02-28 The Trustees Of The University Of Pennsylvania Methods of treating or preventing periodontitis and diseases associated with periodontitis
RU2713257C1 (ru) * 2019-05-06 2020-02-04 Жанна Владимировна Вечеркина Способ лечения хронического апикального периодонтита

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Also Published As

Publication number Publication date
US5270365A (en) 1993-12-14
WO1993011774A1 (en) 1993-06-24
CZ148794A3 (en) 1995-03-15
HK1000114A1 (en) 1997-12-05
NZ246274A (en) 1997-02-24
DE69218624D1 (de) 1997-04-30
HU9401378D0 (en) 1994-08-29
SK72794A3 (en) 1995-04-12
KR100258667B1 (ko) 2000-07-01
IL104109A0 (en) 1993-05-13
CA2122498A1 (en) 1993-06-24
LV12084B (en) 1998-11-20
EP0617624B1 (en) 1997-03-26
KR940703676A (ko) 1994-12-12
JP2825654B2 (ja) 1998-11-18
NO942267L (no) 1994-06-16
HUT68788A (en) 1995-07-28
NO942267D0 (no) 1994-06-16
ZA929712B (en) 1993-06-14
LV12084A (lv) 1998-07-20
JPH07502506A (ja) 1995-03-16
IL104109A (en) 1997-02-18
SK280628B6 (sk) 2000-05-16
ATE150646T1 (de) 1997-04-15
AU675417B2 (en) 1997-02-06
NO306197B1 (no) 1999-10-04
GR3022951T3 (en) 1997-06-30
CZ282902B6 (cs) 1997-11-12
DK0617624T3 (da) 1997-04-21
DE69218624T2 (de) 1997-08-07
CY2054B1 (en) 1998-04-30
HU221807B1 (hu) 2003-01-28
AU3242093A (en) 1993-07-19
EP0617624A1 (en) 1994-10-05

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