SK279251B6 - [2r,3r(2r',3r'),6r,7s,8s,9r,10r]-3-(2',3'-dihydrox - Google Patents

[2r,3r(2r',3r'),6r,7s,8s,9r,10r]-3-(2',3'-dihydrox Download PDF

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Publication number
SK279251B6
SK279251B6 SK3414-92A SK341492A SK279251B6 SK 279251 B6 SK279251 B6 SK 279251B6 SK 341492 A SK341492 A SK 341492A SK 279251 B6 SK279251 B6 SK 279251B6
Authority
SK
Slovakia
Prior art keywords
formula
methyl
dioxabicyclo
compounds
pentamethyl
Prior art date
Application number
SK3414-92A
Other languages
English (en)
Slovak (sk)
Other versions
SK341492A3 (en
Inventor
Dagmar H�Ltje
Ulf Preuschoff
Christian Eeckhout
Original Assignee
Solvay Pharmaceuticals Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Solvay Pharmaceuticals Gmbh filed Critical Solvay Pharmaceuticals Gmbh
Publication of SK341492A3 publication Critical patent/SK341492A3/sk
Publication of SK279251B6 publication Critical patent/SK279251B6/sk

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
SK3414-92A 1992-01-07 1992-11-18 [2r,3r(2r',3r'),6r,7s,8s,9r,10r]-3-(2',3'-dihydrox SK279251B6 (sk)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4200145A DE4200145A1 (de) 1992-01-07 1992-01-07 7,10-epoxy-oxacyclododecan-derivate, verfahren und zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Publications (2)

Publication Number Publication Date
SK341492A3 SK341492A3 (en) 1995-05-10
SK279251B6 true SK279251B6 (sk) 1998-08-05

Family

ID=6449136

Family Applications (1)

Application Number Title Priority Date Filing Date
SK3414-92A SK279251B6 (sk) 1992-01-07 1992-11-18 [2r,3r(2r',3r'),6r,7s,8s,9r,10r]-3-(2',3'-dihydrox

Country Status (28)

Country Link
US (1) US5418224A (uk)
EP (1) EP0550895B1 (uk)
JP (1) JP3300084B2 (uk)
KR (1) KR100273937B1 (uk)
CN (1) CN1033646C (uk)
AT (1) ATE155478T1 (uk)
AU (1) AU667699B2 (uk)
CA (1) CA2086811C (uk)
CZ (1) CZ281773B6 (uk)
DE (2) DE4200145A1 (uk)
DK (1) DK0550895T3 (uk)
DZ (1) DZ1652A1 (uk)
ES (1) ES2104808T3 (uk)
FI (1) FI106862B (uk)
GR (1) GR3024859T3 (uk)
HK (1) HK1014003A1 (uk)
HU (2) HU212272B (uk)
IL (1) IL104158A (uk)
LT (1) LT3015B (uk)
LV (1) LV10458B (uk)
MX (1) MX9300045A (uk)
NO (1) NO179586C (uk)
PH (1) PH30098A (uk)
RU (1) RU2107070C1 (uk)
SK (1) SK279251B6 (uk)
TW (1) TW238308B (uk)
UA (1) UA29393C2 (uk)
ZA (1) ZA9339B (uk)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3462505B2 (ja) * 1995-10-13 2003-11-05 ノイロサーチ アクティーゼルスカブ ８−アザビシクロ［３．２．１］オクト−２−エン誘導体、それらの製造及び使用
US6077943A (en) * 1996-03-01 2000-06-20 Takeda Chemical Industries, Ltd. Method of producing erythromycin derivative
AU2231097A (en) * 1996-03-01 1997-09-16 Kitasato Institute, The Processes for the preparation of erythromycin derivatives
DE19644195A1 (de) * 1996-10-24 1998-04-30 Solvay Pharm Gmbh 10,13,15-Trioxatricyclo[9.2.1.1.·9·.·6·]-pentadecanon-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
US6165985A (en) * 1998-02-13 2000-12-26 Solvay Pharmaceuticals Gmbh 11-acetyl-12,13-dioxabicyclo[8.2.1]-tridecenone derivatives, processes for their preparation and pharmaceutical compositions comprising them
DE19805822B4 (de) * 1998-02-13 2009-02-05 Solvay Pharmaceuticals Gmbh 11-Acetyl-12,13-dioxabicyclo[8.2.1]tridecenon-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE60027015T2 (de) 2000-08-17 2006-10-05 The Kitasato Institute Pseudoerythromycin-derivate
EP1392679B1 (de) * 2001-05-10 2005-11-02 Solvay Pharmaceuticals GmbH Neue 1-amidomethylcarbonyl-piperidinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US20040067896A1 (en) * 2002-07-25 2004-04-08 The Kitasato Institute Novel pseudoerythromycin derivatives
ES2338789T3 (es) 2003-06-18 2010-05-12 Tranzyme Pharma Inc. Antagonistas macrociclicos del receptor de motilina.
US7582611B2 (en) * 2005-05-24 2009-09-01 Pfizer Inc. Motilide compounds
BRPI0619556A2 (pt) * 2005-12-08 2011-10-04 Pfizer processo para desmetilação de grupo 3' -dimetil amino de compostos eritromicina
CN101528765B (zh) 2006-09-11 2015-04-22 欧塞拉治疗有限公司 用于治疗胃肠动力障碍病症的促胃动素受体的大环拮抗剂
MX2009005977A (es) * 2006-12-05 2009-06-17 Pfizer Polimorfos de motilida.
US20080287371A1 (en) * 2007-05-17 2008-11-20 Tranzyme Pharma Inc. Macrocyclic antagonists of the motilin receptor for modulation of the migrating motor complex
US9682126B2 (en) * 2013-03-25 2017-06-20 Zeria Pharmaceutical Co., Ltd. Postprandial gastrokinetic agent

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3725385A (en) * 1970-11-02 1973-04-03 Abbott Lab Process for the demethylation of 3-amino macrolides
US5106961A (en) * 1987-05-26 1992-04-21 Eli Lilly And Company Erythromycin ring-contracted derivatives
CA1321581C (en) * 1987-05-26 1993-08-24 Herbert A. Kirst Ring-contracted macrolides
US4920102A (en) * 1988-04-18 1990-04-24 Eli Lilly And Company Method for treating gastrointestinal disorders

Also Published As

Publication number Publication date
LV10458A (lv) 1995-02-20
RU2107070C1 (ru) 1998-03-20
US5418224A (en) 1995-05-23
HUT66234A (en) 1994-10-28
NO179586B (no) 1996-07-29
HU210216A9 (en) 1995-02-28
HU9204076D0 (en) 1993-04-28
ATE155478T1 (de) 1997-08-15
AU3103693A (en) 1993-07-08
HU212272B (en) 1996-04-29
DE4200145A1 (de) 1993-07-08
UA29393C2 (uk) 2000-11-15
FI930051A (fi) 1993-07-08
JPH07247299A (ja) 1995-09-26
SK341492A3 (en) 1995-05-10
AU667699B2 (en) 1996-04-04
PH30098A (en) 1996-12-27
CN1075320A (zh) 1993-08-18
FI930051A0 (fi) 1993-01-07
MX9300045A (es) 1993-12-01
CN1033646C (zh) 1996-12-25
EP0550895B1 (de) 1997-07-16
CA2086811C (en) 2003-12-09
KR100273937B1 (ko) 2000-12-15
KR930016436A (ko) 1993-08-26
DK0550895T3 (da) 1997-08-25
CZ281773B6 (cs) 1997-01-15
IL104158A0 (en) 1993-05-13
NO930029L (no) 1993-07-08
NO930029D0 (no) 1993-01-06
TW238308B (uk) 1995-01-11
LV10458B (en) 1996-02-20
LT3015B (lt) 1994-08-25
LTIP187A (lt) 1994-03-25
JP3300084B2 (ja) 2002-07-08
FI106862B (fi) 2001-04-30
DZ1652A1 (fr) 2002-02-17
HK1014003A1 (en) 1999-09-17
CZ341492A3 (en) 1993-07-14
GR3024859T3 (en) 1998-01-30
NO179586C (no) 1996-11-06
EP0550895A1 (de) 1993-07-14
ZA9339B (en) 1993-08-05
IL104158A (en) 1997-07-13
ES2104808T3 (es) 1997-10-16
DE59208710D1 (de) 1997-08-21
CA2086811A1 (en) 1993-07-08

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