LT3015B - 4,13-dioksabiciklo£8.2.1|tridekanono dariniai, ju gavimo budas, tarpiniai produktai jiems gauti ir juos turincios farmacines kompozicijos - Google Patents

4,13-dioksabiciklo£8.2.1|tridekanono dariniai, ju gavimo budas, tarpiniai produktai jiems gauti ir juos turincios farmacines kompozicijos Download PDF

Info

Publication number
LT3015B
LT3015B LTIP187A LTIP187A LT3015B LT 3015 B LT3015 B LT 3015B LT IP187 A LTIP187 A LT IP187A LT IP187 A LTIP187 A LT IP187A LT 3015 B LT3015 B LT 3015B
Authority
LT
Lithuania
Prior art keywords
formula
methyl
dioxabicyclo
derivatives
compounds
Prior art date
Application number
LTIP187A
Other languages
English (en)
Lithuanian (lt)
Inventor
Dagmar Hoeltje
Ulf Preuschoff
Christian Eeckhout
Original Assignee
Kali Chemie Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kali Chemie Pharma Gmbh filed Critical Kali Chemie Pharma Gmbh
Publication of LTIP187A publication Critical patent/LTIP187A/lt
Publication of LT3015B publication Critical patent/LT3015B/lt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
LTIP187A 1992-01-07 1992-12-22 4,13-dioksabiciklo£8.2.1|tridekanono dariniai, ju gavimo budas, tarpiniai produktai jiems gauti ir juos turincios farmacines kompozicijos LT3015B (lt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4200145A DE4200145A1 (de) 1992-01-07 1992-01-07 7,10-epoxy-oxacyclododecan-derivate, verfahren und zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Publications (2)

Publication Number Publication Date
LTIP187A LTIP187A (lt) 1994-03-25
LT3015B true LT3015B (lt) 1994-08-25

Family

ID=6449136

Family Applications (1)

Application Number Title Priority Date Filing Date
LTIP187A LT3015B (lt) 1992-01-07 1992-12-22 4,13-dioksabiciklo£8.2.1|tridekanono dariniai, ju gavimo budas, tarpiniai produktai jiems gauti ir juos turincios farmacines kompozicijos

Country Status (28)

Country Link
US (1) US5418224A (uk)
EP (1) EP0550895B1 (uk)
JP (1) JP3300084B2 (uk)
KR (1) KR100273937B1 (uk)
CN (1) CN1033646C (uk)
AT (1) ATE155478T1 (uk)
AU (1) AU667699B2 (uk)
CA (1) CA2086811C (uk)
CZ (1) CZ281773B6 (uk)
DE (2) DE4200145A1 (uk)
DK (1) DK0550895T3 (uk)
DZ (1) DZ1652A1 (uk)
ES (1) ES2104808T3 (uk)
FI (1) FI106862B (uk)
GR (1) GR3024859T3 (uk)
HK (1) HK1014003A1 (uk)
HU (2) HU212272B (uk)
IL (1) IL104158A (uk)
LT (1) LT3015B (uk)
LV (1) LV10458B (uk)
MX (1) MX9300045A (uk)
NO (1) NO179586C (uk)
PH (1) PH30098A (uk)
RU (1) RU2107070C1 (uk)
SK (1) SK279251B6 (uk)
TW (1) TW238308B (uk)
UA (1) UA29393C2 (uk)
ZA (1) ZA9339B (uk)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TR199800628T2 (xx) * 1995-10-13 1998-07-21 Neurosearch A/S 8-Azabisiklo$3.2.1]okt-2-en t�revleri, bunlar�n haz�rlanmas� ve kullan�m�.
US6077943A (en) * 1996-03-01 2000-06-20 Takeda Chemical Industries, Ltd. Method of producing erythromycin derivative
AU2231097A (en) * 1996-03-01 1997-09-16 Kitasato Institute, The Processes for the preparation of erythromycin derivatives
DE19644195A1 (de) * 1996-10-24 1998-04-30 Solvay Pharm Gmbh 10,13,15-Trioxatricyclo[9.2.1.1.·9·.·6·]-pentadecanon-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
US6165985A (en) * 1998-02-13 2000-12-26 Solvay Pharmaceuticals Gmbh 11-acetyl-12,13-dioxabicyclo[8.2.1]-tridecenone derivatives, processes for their preparation and pharmaceutical compositions comprising them
DE19805822B4 (de) * 1998-02-13 2009-02-05 Solvay Pharmaceuticals Gmbh 11-Acetyl-12,13-dioxabicyclo[8.2.1]tridecenon-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE60027015T2 (de) * 2000-08-17 2006-10-05 The Kitasato Institute Pseudoerythromycin-derivate
EP1392679B1 (de) * 2001-05-10 2005-11-02 Solvay Pharmaceuticals GmbH Neue 1-amidomethylcarbonyl-piperidinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US20040067896A1 (en) * 2002-07-25 2004-04-08 The Kitasato Institute Novel pseudoerythromycin derivatives
JP4928261B2 (ja) 2003-06-18 2012-05-09 トランザイム・ファーマ・インコーポレイテッド モチリン受容体の大環状拮抗薬
US7582611B2 (en) * 2005-05-24 2009-09-01 Pfizer Inc. Motilide compounds
EP1960414A4 (en) * 2005-12-08 2008-12-17 Pfizer METHOD FOR DEMETHYLATING THE 3-DIMETHYLAMINOGRUPPE OF ERYTHROMYCIN COMPOUNDS
EP2431380A3 (en) 2006-09-11 2013-07-03 Tranzyme Pharma, Inc. Macrocyclic antagonist of the motilin receptor for treatment of gastrointestinal dysmotility disorders
CA2670482C (en) * 2006-12-05 2011-10-11 Pfizer Inc. Motilide polymorphs
US20080287371A1 (en) * 2007-05-17 2008-11-20 Tranzyme Pharma Inc. Macrocyclic antagonists of the motilin receptor for modulation of the migrating motor complex
TWI662967B (zh) * 2013-03-25 2019-06-21 日商志瑞亞新藥工業股份有限公司 食後期之胃運動亢進劑

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2154032B2 (de) 1970-11-02 1979-05-10 Abbott Laboratories, Chicago, Ill. (V.St.A.) Verfahren zur Demethylierung des Dimethylaminorestes in Erythromycin-AnÜbiotika
EP0349100A2 (en) 1988-04-18 1990-01-03 Eli Lilly And Company Macrolide compositions for treating gastro-intestinal motility disorders

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1321581C (en) * 1987-05-26 1993-08-24 Herbert A. Kirst Ring-contracted macrolides
US5106961A (en) * 1987-05-26 1992-04-21 Eli Lilly And Company Erythromycin ring-contracted derivatives

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2154032B2 (de) 1970-11-02 1979-05-10 Abbott Laboratories, Chicago, Ill. (V.St.A.) Verfahren zur Demethylierung des Dimethylaminorestes in Erythromycin-AnÜbiotika
EP0349100A2 (en) 1988-04-18 1990-01-03 Eli Lilly And Company Macrolide compositions for treating gastro-intestinal motility disorders

Also Published As

Publication number Publication date
ES2104808T3 (es) 1997-10-16
LV10458B (en) 1996-02-20
HUT66234A (en) 1994-10-28
PH30098A (en) 1996-12-27
GR3024859T3 (en) 1998-01-30
LV10458A (lv) 1995-02-20
DE4200145A1 (de) 1993-07-08
CN1033646C (zh) 1996-12-25
SK341492A3 (en) 1995-05-10
KR930016436A (ko) 1993-08-26
ZA9339B (en) 1993-08-05
IL104158A (en) 1997-07-13
FI930051A (fi) 1993-07-08
HU212272B (en) 1996-04-29
IL104158A0 (en) 1993-05-13
DE59208710D1 (de) 1997-08-21
CA2086811C (en) 2003-12-09
HK1014003A1 (en) 1999-09-17
CZ281773B6 (cs) 1997-01-15
ATE155478T1 (de) 1997-08-15
SK279251B6 (sk) 1998-08-05
NO930029D0 (no) 1993-01-06
FI106862B (fi) 2001-04-30
RU2107070C1 (ru) 1998-03-20
FI930051A0 (fi) 1993-01-07
CZ341492A3 (en) 1993-07-14
TW238308B (uk) 1995-01-11
EP0550895A1 (de) 1993-07-14
LTIP187A (lt) 1994-03-25
HU9204076D0 (en) 1993-04-28
EP0550895B1 (de) 1997-07-16
AU667699B2 (en) 1996-04-04
AU3103693A (en) 1993-07-08
MX9300045A (es) 1993-12-01
JPH07247299A (ja) 1995-09-26
NO930029L (no) 1993-07-08
DZ1652A1 (fr) 2002-02-17
HU210216A9 (en) 1995-02-28
CA2086811A1 (en) 1993-07-08
CN1075320A (zh) 1993-08-18
KR100273937B1 (ko) 2000-12-15
UA29393C2 (uk) 2000-11-15
JP3300084B2 (ja) 2002-07-08
NO179586B (no) 1996-07-29
US5418224A (en) 1995-05-23
DK0550895T3 (da) 1997-08-25
NO179586C (no) 1996-11-06

Similar Documents

Publication Publication Date Title
LT3015B (lt) 4,13-dioksabiciklo£8.2.1|tridekanono dariniai, ju gavimo budas, tarpiniai produktai jiems gauti ir juos turincios farmacines kompozicijos
RU2181727C2 (ru) Производные 10,13,15-триоксатрицикло (9.2.1.1.9.6)-пентадеканона, способ их получения и содержащие эти соединения лекарственные средства
US6165985A (en) 11-acetyl-12,13-dioxabicyclo[8.2.1]-tridecenone derivatives, processes for their preparation and pharmaceutical compositions comprising them
MXPA97007974A (en) Derivatives of 10, 13, 15-trioxatriciclo [9.2.1.1 9.6] -pentadecanona, procedures for its preparation and medicines that contain these compounds
KR100584017B1 (ko) 11-아세틸-12,13-디옥사바이시클로〔8.2.1〕-트리데케논 유도체,이의 제조방법 및 이 화합물을 포함하는 약제
MXPA99001491A (en) Derivatives of 11-acetyl-12,13 dioxabiciclo [8.2.1] tridecenone, procedure for its preparation, and medications containing these compounds

Legal Events

Date Code Title Description
PD9A Change of patent owner

Free format text: SOLVAY PHARMACEUTICALS GMBH,HANS-BOECKLER-ALLEE 20, D-30173 HANNOVER,DE,19970725

MM9A Lapsed patents

Effective date: 20081222