LT3015B - 4,13-dioksabiciklo£8.2.1|tridekanono dariniai, ju gavimo budas, tarpiniai produktai jiems gauti ir juos turincios farmacines kompozicijos - Google Patents

4,13-dioksabiciklo£8.2.1|tridekanono dariniai, ju gavimo budas, tarpiniai produktai jiems gauti ir juos turincios farmacines kompozicijos Download PDF

Info

Publication number
LT3015B
LT3015B LTIP187A LTIP187A LT3015B LT 3015 B LT3015 B LT 3015B LT IP187 A LTIP187 A LT IP187A LT IP187 A LTIP187 A LT IP187A LT 3015 B LT3015 B LT 3015B
Authority
LT
Lithuania
Prior art keywords
formula
methyl
dioxabicyclo
derivatives
compounds
Prior art date
Application number
LTIP187A
Other languages
English (en)
Lithuanian (lt)
Inventor
Dagmar Hoeltje
Ulf Preuschoff
Christian Eeckhout
Original Assignee
Kali Chemie Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kali Chemie Pharma Gmbh filed Critical Kali Chemie Pharma Gmbh
Publication of LTIP187A publication Critical patent/LTIP187A/lt
Publication of LT3015B publication Critical patent/LT3015B/lt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08Hetero rings containing eight or more ring members, e.g. erythromycins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
LTIP187A 1992-01-07 1992-12-22 4,13-dioksabiciklo£8.2.1|tridekanono dariniai, ju gavimo budas, tarpiniai produktai jiems gauti ir juos turincios farmacines kompozicijos LT3015B (lt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4200145A DE4200145A1 (de) 1992-01-07 1992-01-07 7,10-epoxy-oxacyclododecan-derivate, verfahren und zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Publications (2)

Publication Number Publication Date
LTIP187A LTIP187A (lt) 1994-03-25
LT3015B true LT3015B (lt) 1994-08-25

Family

ID=6449136

Family Applications (1)

Application Number Title Priority Date Filing Date
LTIP187A LT3015B (lt) 1992-01-07 1992-12-22 4,13-dioksabiciklo£8.2.1|tridekanono dariniai, ju gavimo budas, tarpiniai produktai jiems gauti ir juos turincios farmacines kompozicijos

Country Status (28)

Country Link
US (1) US5418224A (uk)
EP (1) EP0550895B1 (uk)
JP (1) JP3300084B2 (uk)
KR (1) KR100273937B1 (uk)
CN (1) CN1033646C (uk)
AT (1) ATE155478T1 (uk)
AU (1) AU667699B2 (uk)
CA (1) CA2086811C (uk)
CZ (1) CZ281773B6 (uk)
DE (2) DE4200145A1 (uk)
DK (1) DK0550895T3 (uk)
DZ (1) DZ1652A1 (uk)
ES (1) ES2104808T3 (uk)
FI (1) FI106862B (uk)
GR (1) GR3024859T3 (uk)
HK (1) HK1014003A1 (uk)
HU (2) HU212272B (uk)
IL (1) IL104158A (uk)
LT (1) LT3015B (uk)
LV (1) LV10458B (uk)
MX (1) MX9300045A (uk)
NO (1) NO179586C (uk)
PH (1) PH30098A (uk)
RU (1) RU2107070C1 (uk)
SK (1) SK279251B6 (uk)
TW (1) TW238308B (uk)
UA (1) UA29393C2 (uk)
ZA (1) ZA9339B (uk)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3462505B2 (ja) * 1995-10-13 2003-11-05 ノイロサーチ アクティーゼルスカブ 8−アザビシクロ[3.2.1]オクト−2−エン誘導体、それらの製造及び使用
US6077943A (en) * 1996-03-01 2000-06-20 Takeda Chemical Industries, Ltd. Method of producing erythromycin derivative
AU2231097A (en) * 1996-03-01 1997-09-16 Kitasato Institute, The Processes for the preparation of erythromycin derivatives
DE19644195A1 (de) * 1996-10-24 1998-04-30 Solvay Pharm Gmbh 10,13,15-Trioxatricyclo[9.2.1.1.·9·.·6·]-pentadecanon-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
US6165985A (en) * 1998-02-13 2000-12-26 Solvay Pharmaceuticals Gmbh 11-acetyl-12,13-dioxabicyclo[8.2.1]-tridecenone derivatives, processes for their preparation and pharmaceutical compositions comprising them
DE19805822B4 (de) * 1998-02-13 2009-02-05 Solvay Pharmaceuticals Gmbh 11-Acetyl-12,13-dioxabicyclo[8.2.1]tridecenon-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE60027015T2 (de) 2000-08-17 2006-10-05 The Kitasato Institute Pseudoerythromycin-derivate
EP1392679B1 (de) * 2001-05-10 2005-11-02 Solvay Pharmaceuticals GmbH Neue 1-amidomethylcarbonyl-piperidinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US20040067896A1 (en) * 2002-07-25 2004-04-08 The Kitasato Institute Novel pseudoerythromycin derivatives
ES2338789T3 (es) 2003-06-18 2010-05-12 Tranzyme Pharma Inc. Antagonistas macrociclicos del receptor de motilina.
US7582611B2 (en) * 2005-05-24 2009-09-01 Pfizer Inc. Motilide compounds
BRPI0619556A2 (pt) * 2005-12-08 2011-10-04 Pfizer processo para desmetilação de grupo 3' -dimetil amino de compostos eritromicina
CN101528765B (zh) 2006-09-11 2015-04-22 欧塞拉治疗有限公司 用于治疗胃肠动力障碍病症的促胃动素受体的大环拮抗剂
MX2009005977A (es) * 2006-12-05 2009-06-17 Pfizer Polimorfos de motilida.
US20080287371A1 (en) * 2007-05-17 2008-11-20 Tranzyme Pharma Inc. Macrocyclic antagonists of the motilin receptor for modulation of the migrating motor complex
US9682126B2 (en) * 2013-03-25 2017-06-20 Zeria Pharmaceutical Co., Ltd. Postprandial gastrokinetic agent

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2154032B2 (de) 1970-11-02 1979-05-10 Abbott Laboratories, Chicago, Ill. (V.St.A.) Verfahren zur Demethylierung des Dimethylaminorestes in Erythromycin-AnÜbiotika
EP0349100A2 (en) 1988-04-18 1990-01-03 Eli Lilly And Company Macrolide compositions for treating gastro-intestinal motility disorders

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5106961A (en) * 1987-05-26 1992-04-21 Eli Lilly And Company Erythromycin ring-contracted derivatives
CA1321581C (en) * 1987-05-26 1993-08-24 Herbert A. Kirst Ring-contracted macrolides

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2154032B2 (de) 1970-11-02 1979-05-10 Abbott Laboratories, Chicago, Ill. (V.St.A.) Verfahren zur Demethylierung des Dimethylaminorestes in Erythromycin-AnÜbiotika
EP0349100A2 (en) 1988-04-18 1990-01-03 Eli Lilly And Company Macrolide compositions for treating gastro-intestinal motility disorders

Also Published As

Publication number Publication date
LV10458A (lv) 1995-02-20
RU2107070C1 (ru) 1998-03-20
US5418224A (en) 1995-05-23
HUT66234A (en) 1994-10-28
NO179586B (no) 1996-07-29
HU210216A9 (en) 1995-02-28
HU9204076D0 (en) 1993-04-28
ATE155478T1 (de) 1997-08-15
AU3103693A (en) 1993-07-08
HU212272B (en) 1996-04-29
DE4200145A1 (de) 1993-07-08
UA29393C2 (uk) 2000-11-15
FI930051A (fi) 1993-07-08
JPH07247299A (ja) 1995-09-26
SK341492A3 (en) 1995-05-10
AU667699B2 (en) 1996-04-04
PH30098A (en) 1996-12-27
CN1075320A (zh) 1993-08-18
FI930051A0 (fi) 1993-01-07
MX9300045A (es) 1993-12-01
CN1033646C (zh) 1996-12-25
EP0550895B1 (de) 1997-07-16
CA2086811C (en) 2003-12-09
KR100273937B1 (ko) 2000-12-15
KR930016436A (ko) 1993-08-26
SK279251B6 (sk) 1998-08-05
DK0550895T3 (da) 1997-08-25
CZ281773B6 (cs) 1997-01-15
IL104158A0 (en) 1993-05-13
NO930029L (no) 1993-07-08
NO930029D0 (no) 1993-01-06
TW238308B (uk) 1995-01-11
LV10458B (en) 1996-02-20
LTIP187A (lt) 1994-03-25
JP3300084B2 (ja) 2002-07-08
FI106862B (fi) 2001-04-30
DZ1652A1 (fr) 2002-02-17
HK1014003A1 (en) 1999-09-17
CZ341492A3 (en) 1993-07-14
GR3024859T3 (en) 1998-01-30
NO179586C (no) 1996-11-06
EP0550895A1 (de) 1993-07-14
ZA9339B (en) 1993-08-05
IL104158A (en) 1997-07-13
ES2104808T3 (es) 1997-10-16
DE59208710D1 (de) 1997-08-21
CA2086811A1 (en) 1993-07-08

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Legal Events

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PD9A Change of patent owner

Free format text: SOLVAY PHARMACEUTICALS GMBH,HANS-BOECKLER-ALLEE 20, D-30173 HANNOVER,DE,19970725

MM9A Lapsed patents

Effective date: 20081222